Martin Thoolen

4.0k citations

67 papers · 3.2k indexed · 1 hit paper · h-index 25

Impact in

Biochemistry top 1%
- Lipid metabolism and biosynthesis
Clinical Biochemistry top 2%

Papers in

Cellular and Molecular Neuroscience 18
- Neuroscience and Neuropharmacology Research 12
Biochemistry 7
- Eicosanoids and Hypertension Pharmacology 6

Co-authors: Julio C. Medina Leping Li Kevin D. Lustig Susan W. Schwendner Bei Shan David J. Mangelsdorf Shelley Wang Joshua R. Schultz
Journals: European Journal of Pharmacology (13 papers)Journal of Cardiovascular Pharmacology (7 papers)Bioorganic & Medicinal Chemistry Letters (4 papers)Journal of Medicinal Chemistry (3 papers)Journal of Pharmacy and Pharmacology (3 papers)
Partner nations: United States Netherlands New Zealand

In The Last Decade

Martin Thoolen

67 papers receiving 3.0k citations

Hit Papers

align trajectories log scale

Role of LXRs in control of lipogenesis 2000 · 1.4k citations

Peers

Countries citing papers authored by Martin Thoolen

Since Specialization

Citations

This map shows the geographic impact of Martin Thoolen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Martin Thoolen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Martin Thoolen more than expected).

Fields of papers citing papers by Martin Thoolen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Martin Thoolen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Martin Thoolen. The network helps show where Martin Thoolen may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Martin Thoolen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Martin Thoolen Line = papers co-authored together Martin Thoolen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Effect of Itraconazole, a CYP3A4 Inhibitor, and Rifampin, a CYP3A4 Inducer, on the Pharmacokinetics of Vatiquinone Clinical Pharmacology in Drug Development ·秀一稲村, Martin Thoolen, Jiyuan Ma, Diksha Kaushik, Julia Strand, Ronald Kong	2024	4
2	Absorption, distribution, metabolism and excretion of ¹⁴ C-vatiquinone in rats, dogs, and human subjects Xenobiotica ·Jiyuan Ma, 秀一稲村, Alexander Milenkin, Peter P. Giannousis, Martin Thoolen, Qing Ye, Julia Strand, Matthew B. Klein, Ronald Kong	2023	5
3	Treatment of Leber's hereditary optic neuropathy (LHON): Results using a novel quinone, EPI-743 Investigative Ophthalmology & Visual Science ·Carlos Filipe Chicani, Edward Chu, Fred N. Ross‐Cisneros, Д. В. Калинин, Katsuyuki Murase, Martin Thoolen, Guy Miller, Alfredo A. Sadun	2013	3
4	EPI-743 reverses the progression of the pediatric mitochondrial disease—Genetically defined Leigh Syndrome Molecular Genetics and Metabolism ·Diego Martinelli, Michela Catteruccia, Fiorella Piemonte, Anna Pastore, Giulia Tozzi, Carlo Dionisi‐Vici, Giuseppe Pontrelli, Tiziana Corsetti, Susanna Livadiotti, Viktoria Kheifets, A. Scott Hinman, William D. Shrader, Martin Thoolen, Matthew B. Klein, Enrico Bertini, Guy Miller	2012	149
5	Brain uptake of Tc99m-HMPAO correlates with clinical response to the novel redox modulating agent EPI-743 in patients with mitochondrial disease Molecular Genetics and Metabolism ·Francis G. Blankenberg, Stephen L. Kinsman, Bruce H. Cohen, Michael L. Goris, Kenneth Spicer, Susan Perlman, Elliot J. Krane, Viktoria Kheifets, Martin Thoolen, Guy Miller, Gregory M. Enns	2012	27
6	α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging Bioorganic & Medicinal Chemistry Letters ·William D. Shrader, Akiko Amagata, Marius Lazurca, Gregory M. Enns, A. Scott Hinman, Chi Zhang, Viktoria Kheifets, M. S. Silva Yonara, Edgar Lee, Z. Nordatul Akmar, Katsuyuki Murase, Alfredo A. Sadun, Martin Thoolen, Ünal Bulut, Guy Miller	2011	70
7	Initial experience in the treatment of inherited mitochondrial disease with EPI-743 Molecular Genetics and Metabolism ·Gregory M. Enns, Stephen L. Kinsman, Susan Perlman, Kenneth Spicer, José E. Abdenur, Bruce H. Cohen, Akiko Amagata, Marius Lazurca, Viktoria Kheifets, William D. Shrader, Martin Thoolen, Francis G. Blankenberg, Guy Miller	2011	148
8	Ring constrained analogues of β-alanine-containing GPIIb/IIIa receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Thais M. Sielecki, John Wityak, Yara L. Diniz, Shaker A. Mousa, Martin Thoolen, Ruth R. Wexler, Richard E. Olson	2000	6
9	Role of LXRs in control of lipogenesis Genes & Development ·Joshua R. Schultz, Hua Tu, Sandra VALABREGUE-PERRY, Joyce J. Repa, Julio C. Medina, Leping Li, Susan W. Schwendner, Shelley Wang, Martin Thoolen, David J. Mangelsdorf, Kevin D. Lustig, Bei Shan Hit paper breakdown →	2000	1394
10	Oral Antiplatelet Efficacy and Specificity of a Novel Nonpeptide Platelet GPIIb/IIIa Receptor Antagonist, DMP 802 Journal of Cardiovascular Pharmacology ·Shaker A. Mousa, Richard E. Olson, Jeffrey M. Bozarth, William Lorelli, Mark S. Forsythe, Robert H.A. Tremblay, Zhaoquan Liao, J Jayasudhakar, Jean-Francois Mas, Ram P. Kapil, John Wityak, Thais M. Sielecki, Ruth R. Wexler, Martin Thoolen, Andrew Slee, Thomas M. Reilly, Paul Anderson, Paul A. Friedman	1998	13
11	Novel nonpeptide antiplatelet glycoprotein llb/llla receptor antagonist, DMP754 Coronary Artery Disease ·Shaker A. Mousa, Mark S. Forsythe, William Lorelli, Jeffrey M. Bozarth, Chu‐Biao Xue, John Wityak, Thais M. Sielecki, Violandari Violandari, William F. DeGrado, Ram P. Kapil, Munir Hussain, Ruth R. Wexler, Martin Thoolen, Thomas M. Reilly	1996	41
12	Preservation of Regional and Global Left Ventricular Function by Intracoronary Infusion with Oxygenated Fluorocarbon Emulsion Therox^TMin Dogs Biomaterials Artificial Cells and Immobilization Biotechnology ·Martin Thoolen, R.W. Burklin, Mustafa Badr Hussein, Kamar Soufan, Pieter B.M.W.M. Timmermans	1993	2
13	Antiplatelet Efficacy and Specificity of DMP728, a Novel Platelet GPIIb/llla Receptor Antagonist Cardiology ·Shaker A. Mousa, Grigoriy Sergeev, Mark S. Forsythe, William Lorelli, Martin Thoolen, N. Ramachandran, Sharon Jackson, Fabiana de Pontes Rubira, Thomas M. Reilly	1993	40
14	Evaluation of the effect of azapropazone on neutrophil migration in regional myocardial ischaemia/reperfusion injury in rabbits British Journal of Pharmacology ·Shaker A. Mousa, Nenad Stamenkovic, Martin Thoolen, Ronald D. Smith	1990	4
15	Monoclonal antibodies directed against basic fibroblast growth factor which inhibit its biological activity in vitro and in vivo Biochemical and Biophysical Research Communications ·Thomas M. Reilly, David S. Taylor, William F. Herblin, Martin Thoolen, Andrew T. Chiu, Dennis W. Watson, Pieter B.M.W.M. Timmermans	1989	70
16	Myocardial Cytoprotective Efficacy of Azapropazone in a Canine Heart Model of Regional Ischemia and Reperfusion Journal of Cardiovascular Pharmacology ·Shaker A. Mousa, John Cooney, Martin Thoolen, Pieter B.M.W.M. Timmermans	1989	4
17	Effect of calcium entry blockers on blood pressure and vasoconstrictor responses to alpha-1 adrenoceptor stimulation in conscious spontaneously hypertensive rats Cardiovascular Drugs and Therapy ·Martin Thoolen, Juan Carlos Umpiri Huamani, Andrew T. Chiu, Pieter B.M.W.M. Timmermans	1987	1
18	Effect of azapropazone and allopurinol on myocardial infarct size in rats European Journal of Pharmacology ·S. Nakayama, Martin Thoolen, William M. Mackin, Luis Martínez-González	1987	14
19	Equal potency of nifedipine to inhibit α1-(dobutamine and BDF 6143) and α2-adrenoceptor (B-HT 920) induced pressor responses in pithed rats; lack of effect of phenoxybenzamine European Journal of Pharmacology ·Luis Martínez-González, Martin Thoolen	1987	2
20	Calcium handling in vasoconstriction to stimulation of alpha₁- and alpha₂-adrenoceptors Canadian Journal of Physiology and Pharmacology ·Pieter B.M.W.M. Timmermans, Andrew T. Chiu, Martin Thoolen	1987	24

About Martin Thoolen

Martin Thoolen is a scholar working on Cellular and Molecular Neuroscience, Biochemistry, Clinical Biochemistry, Hematology and Molecular Biology, having authored 67 papers that have together received 3.2k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (24 papers), Neuroscience and Neuropharmacology Research (12 papers), Nitric Oxide and Endothelin Effects (9 papers), Renin-Angiotensin System Studies (7 papers), Eicosanoids and Hypertension Pharmacology (6 papers), Antiplatelet Therapy and Cardiovascular Diseases (6 papers), Mitochondrial Function and Pathology (5 papers) and Heparin-Induced Thrombocytopenia and Thrombosis (5 papers). The work is most often cited by research in Biochemistry (344 citations), Clinical Biochemistry (193 citations), Surgery (1.2k citations), Molecular Biology (1.8k citations) and Cellular and Molecular Neuroscience (419 citations). Martin Thoolen has collaborated with scholars based in United States, Netherlands and New Zealand. Frequent co-authors include Julio C. Medina, Leping Li, Kevin D. Lustig, Susan W. Schwendner, Bei Shan, David J. Mangelsdorf, Shelley Wang, Joshua R. Schultz, Joyce J. Repa and Hua Tu. Their work appears in journals such as European Journal of Pharmacology, Journal of Cardiovascular Pharmacology, Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry and Journal of Pharmacy and Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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