David H. Spencer

12.2k total citations · 1 hit paper
57 papers, 3.8k citations indexed

About

David H. Spencer is a scholar working on Molecular Biology, Hematology and Cancer Research. According to data from OpenAlex, David H. Spencer has authored 57 papers receiving a total of 3.8k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 20 papers in Hematology and 19 papers in Cancer Research. Recurrent topics in David H. Spencer's work include Acute Myeloid Leukemia Research (19 papers), Cancer Genomics and Diagnostics (15 papers) and Epigenetics and DNA Methylation (11 papers). David H. Spencer is often cited by papers focused on Acute Myeloid Leukemia Research (19 papers), Cancer Genomics and Diagnostics (15 papers) and Epigenetics and DNA Methylation (11 papers). David H. Spencer collaborates with scholars based in United States, Canada and United Kingdom. David H. Spencer's co-authors include Maynard V. Olson, Rajinder Kaul, Christopher K. Raymond, Eric Haugen, Chunrong Liu, Ruth Levy, Michael A. Jacobs, Stephen A. Ernst, Iyarit Thaipisuttikul and Colin Manoil and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and JAMA.

In The Last Decade

David H. Spencer

56 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Comprehensive transposon mutant library of Pseudomonas aeruginosa

2003 932 citations David H. Spencer, Maynard V. Olson et al. profile →

Peers

David H. Spencer

GENET

HEMAT

Shih‐Feng Tsai Taiwan

Adam C. Wilkinson United Kingdom

Simon J. McGowan United Kingdom

Richard J. Meyer United States

Patrick M. Slocombe United Kingdom

Albrecht Bindereif Germany

Sally S. Twining United States

David L. Goode Australia

Geoffrey Yarranton United States

Nicole T. Liberati United States

Shih‐Feng Tsai Taiwan

David H. Spencer

1.9k ×0.7

502 ×0.5

GENET

273 ×0.3

HEMAT

195 ×0.3

747 ×1.4

Citations per year, relative to David H. Spencer David H. Spencer (= 1×) peers Shih‐Feng Tsai

Countries citing papers authored by David H. Spencer

Since Specialization

Citations

This map shows the geographic impact of David H. Spencer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David H. Spencer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David H. Spencer more than expected).

Fields of papers citing papers by David H. Spencer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David H. Spencer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David H. Spencer. The network helps show where David H. Spencer may publish in the future.

Co-authorship network of co-authors of David H. Spencer

This figure shows the co-authorship network connecting the top 25 collaborators of David H. Spencer. A scholar is included among the top collaborators of David H. Spencer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David H. Spencer. David H. Spencer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Polonis, Katarzyna, et al.. (2025). Innovations in Short-Read Sequencing Technologies and Their Applications to Clinical Genomics. Clinical Chemistry. 71(1). 97–108. 5 indexed citations

Valentine, Mark C., Amanda Wong, Ling Chen, et al.. (2025). A fully next-generation sequencing-based method of classifying molecular sub-types of endometrial cancer retains prognostic value and expands biomarker targets. International Journal of Gynecological Cancer. 35(2). 100060–100060.

Ruzinova, Marianna B., Ashutosh Kumar, Ryan B. Day, et al.. (2024). Missense Mutations in Myc Box I Influence Nucleocytoplasmic Transport to Promote Leukemogenesis. Clinical Cancer Research. 30(16). 3622–3639. 2 indexed citations

Abel, Haley, Karolyn A. Oetjen, Christopher A. Miller, et al.. (2023). Genomic landscape of TP53-mutated myeloid malignancies. Blood Advances. 7(16). 4586–4598. 15 indexed citations

Zhang, Christine, Wentao Han, Andrew L. Young, et al.. (2023). KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress. Leukemia. 37(4). 728–740. 9 indexed citations

Hou, Ying‐Chen Claire, Julie Neidich, Eric J. Duncavage, David H. Spencer, & Molly C. Schroeder. (2022). Clinical whole‐genome sequencing in cancer diagnosis. Human Mutation. 43(11). 1519–1530. 13 indexed citations

Miller, Christopher A., Jason Walker, Robert S. Fulton, et al.. (2022). Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence. Journal of Molecular Diagnostics. 24(3). 219–223. 14 indexed citations

Warren, Julia T., Ryan R. Cupo, David H. Spencer, et al.. (2021). Heterozygous variants of CLPB are a cause of severe congenital neutropenia. Blood. 139(5). 779–791. 24 indexed citations

Helton, Nichole, Sharon E. Heath, Robert S. Fulton, et al.. (2021). Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells. Leukemia. 36(4). 935–945. 19 indexed citations

10.

Christopher, Matthew, Margery Gang, Andrew J. Menssen, et al.. (2021). Tumor suppressor function of <I>WT1</I> in acute promyelocytic leukemia. Haematologica. 107(1). 342–346. 6 indexed citations

11.

Ghasemi, Reza, et al.. (2020). Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells. Leukemia. 35(2). 404–416. 18 indexed citations

12.

Spencer, David H., David A. Russler‐Germain, Shamika Ketkar, et al.. (2017). CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression. Cell. 168(5). 801–816.e13. 149 indexed citations

13.

Acevedo‐Garcia, Johanna, David H. Spencer, Hannah Thieron, et al.. (2016). mlo ‐based powdery mildew resistance in hexaploid bread wheat generated by a non‐transgenic TILLING approach. Plant Biotechnology Journal. 15(3). 367–378. 134 indexed citations

14.

Russler‐Germain, David A., David H. Spencer, Margaret A. Young, et al.. (2014). The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers. Cancer Cell. 25(4). 442–454. 316 indexed citations

15.

Klco, Jeffery M., David H. Spencer, Chris Miller, et al.. (2014). Functional Heterogeneity of Genetically Defined Subclones in Acute Myeloid Leukemia. Cancer Cell. 25(3). 379–392. 264 indexed citations

16.

Spencer, David H., Jennifer K. Sehn, Haley Abel, et al.. (2013). Comparison of Clinical Targeted Next-Generation Sequence Data from Formalin-Fixed and Fresh-Frozen Tissue Specimens. Journal of Molecular Diagnostics. 15(5). 623–633. 123 indexed citations

17.

Spencer, David H., Manoj Tyagi, Francesco Vallania, et al.. (2013). Performance of Common Analysis Methods for Detecting Low-Frequency Single Nucleotide Variants in Targeted Next-Generation Sequence Data. Journal of Molecular Diagnostics. 16(1). 75–88. 84 indexed citations

18.

D’Argenio, David A., Manhong Wu, Lucas R. Hoffman, et al.. (2007). Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients. Molecular Microbiology. 64(2). 512–533. 278 indexed citations

19.

Spencer, David H., Kerry L. Bubb, & Maynard V. Olson. (2006). Detecting Disease-Causing Mutations in the Human Genome by Haplotype Matching. The American Journal of Human Genetics. 79(5). 958–964. 3 indexed citations

20.

Spencer, David H. & Starr Roxanne Hiltz. (2002). A field study of use of synchronous computer-mediated communication in asynchronous learning networks. 6(4). 124–9. 6 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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