Jack F. Shern

9.6k citations

53 papers · 3.4k indexed · 1 hit paper · h-index 23

Impact in

Oncology top 1%
- CAR-T cell therapy research
Immunology top 5%
- Immune Cell Function and Interaction

Papers in

Neurology 13
- Neuroblastoma Research and Treatments 11
- Neurofibromatosis and Schwannoma Cases 6
Pulmonary and Respiratory Medicine 25
- Sarcoma Diagnosis and Treatment 24

Co-authors: Terry J. Fry Waleed Haso Crystal L. Mackall Rosandra N. Kaplan Meera Murgai Javed Khan Rimas J. Orentas Maria Ingaramo
Journals: Clinical Cancer Research (5 papers)Nature Communications (3 papers)Journal of Biological Chemistry (3 papers)Nature Medicine (2 papers)Cell Reports (2 papers)
Partner nations: United States United Kingdom Canada

In The Last Decade

Jack F. Shern

49 papers receiving 3.4k citations

Hit Papers

align trajectories log scale

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors 2015 · 1.3k citations

Peers

Countries citing papers authored by Jack F. Shern

Since Specialization

Citations

This map shows the geographic impact of Jack F. Shern's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jack F. Shern with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jack F. Shern more than expected).

Fields of papers citing papers by Jack F. Shern

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jack F. Shern. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jack F. Shern. The network helps show where Jack F. Shern may publish in the future.

Co-authors

The 25 scholars most cited alongside Jack F. Shern, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jack F. Shern Line = papers co-authored together Jack F. Shern links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	GPC2-Targeted CAR T Cells Engineered with NFAT-Inducible Membrane-Tethered IL15/IL21 Exhibit Enhanced Activity against Neuroblastoma Cancer Immunology Research ·Reona Okada, Johannes Joppich, Zhong Hui Lim, Taisuke Kondo, Jangsuk Oh, В С Ярочкин, Michael C. Kelly, Septy Indra Santoso, James L. Gulley, Jack F. Shern, Mitchell Ho, Christian S. Hinrichs, Naomi Taylor, Xiyuan Zhang, Rosa Nguyen	2025	1
2	MYCN and KAT2A form a feedforward loop to drive an oncogenic transcriptional program in neuroblastoma Oncogenesis ·Ma Asunción Esteban, 治武伊東, Xiyuan Zhang, Carly M. Sayers, Wendy Fang, Man Xu, Terrence D. Maloney, Aman Dabral, Haiyan Lei, Jenica Yong, Rolf E. Swenson, Jordan L. Meier, Jack F. Shern, Carol J. Thiele	2025	0
3	Daytime SHP2 inhibitor dosing, when immune cell numbers are elevated, shrinks neurofibromas Life Science Alliance ·Niousha Ahmari, Kwangmin Choi, Jianqiang Wu, Tilat A. Rizvi, Ganesh Raj, Whony Rofianto, Mi‐Ok Kim, Xiyuan Zhang, Eva Dombi, Jack F. Shern, David A. Hildeman, Nancy Ratner	2025	0
4	Targeting SWI/SNF ATPases reduces neuroblastoma cell plasticity The EMBO Journal ·Man Xu, 治武伊東, Xiyuan Zhang, Ming Sun, Xingyu Liu, 佳仪黄, B. Angelica Gonzalez-Morales, Wendy Fang, Haiyan Lei, Sung-Hee Sohn, Reona Okada, 曹兴权, Rosa Nguyen, Jack F. Shern, Carol J. Thiele, Ma Asunción Esteban	2024	3
5	Circulating Tumor DNA Is Prognostic in Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group Journal of Clinical Oncology ·Samuel Abbou, Kelly Klega, Junko Tsuji, GaryX Gong, David Hall, Donald A. Barkauskas, Mark Krailo, Carrie Cibulskis, Anwesha Nag, Aaron R. Thorner, George Henry Haydon, Alma Imamović, Jack F. Shern, Steven G. DuBois, Rajkumar Venkatramani, Douglas S. Hawkins, Brian D. Crompton	2023	16
6	Cooperative Armoring of CAR and TCR T Cells by T Cell–Restricted IL15 and IL21 Universally Enhances Solid Tumor Efficacy Clinical Cancer Research ·Rosa Nguyen, Ekaterina Doubrovina, Wan yu Shang, Steeve Laroussi, Reona Okada, Xiyuan Zhang, Arina Clavel, Johannes Joppich, Vadim Dyomin, 于波海, Septy Indra Santoso, 美子小泉, В С Ярочкин, Chao-Ming Hsieh, Mitchell Ho, Jack F. Shern, James L. Gulley, Christian S. Hinrichs	2023	23
7	Childhood cancer data initiative: Status report Pediatric Blood & Cancer ·Subhashini Jagu, Elaine R. Mardis, Mary Frances Wedekind, Brigitte C. Widemann, Abeer M. Alenazy, Balaji Veluswamy, Jack F. Shern, Gregory H. Reaman	2023	2
8	Anti-GD2 Antibodies Conjugated to IL15 and IL21 Mediate Potent Antitumor Cytotoxicity against Neuroblastoma Clinical Cancer Research ·Rosa Nguyen, Xiyuan Zhang, В С Ярочкин, 美子小泉, محمد أردكاني, Michael C. Kelly, Jack F. Shern, Carol J. Thiele	2022	24
9	Defining the Extracellular Matrix of Rhabdomyosarcoma Frontiers in Oncology ·FRANCISCO XAVIER DE ARAÚJO, Zhou Changhal, Narendra Bharathy, Sergei P. Boudko, Elena Pokidysheva, Jack F. Shern, Shinzou IWASAKI, Takako Sasaki, S. Razzaboni, Т С Проказина, Paola Anselmi, Alejandro Gallego, Christopher Hartley, Hans Peter Bächinger, Atiya Mansoor, Sakir H. Gultekin, Noah Berlow, Charles Keller	2021	11
10	Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression Cell stem cell ·Daochun Sun, Xuanhua Xie, Xiyuan Zhang, Zilai Wang, Sameer Farouk Sait, Swathi V. Iyer, Yu-Jung Chen, Shatesh Kumar Sangar, Dan R. Laks, Costa Bonito, Jack F. Shern, Luis F. Parada	2021	24
11	CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG Nature Communications ·Zhihui Liu, Xiyuan Zhang, Haiyan Lei, Norris Lam, Philippe Fauré-Fremiet, Kh. Tahon, 吉田典行, Arnulfo Mendoza, Afnan Mousa Alhawsawi, Jun S. Wei, Javed Khan, Marielle E. Yohe, Jack F. Shern, Carol J. Thiele	2020	36
12	Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence Clinical Cancer Research ·Sneha Ramakrishna, Steven L. Highfill, R. R., Sang M. Nguyen, Haiyan Lei, Jack F. Shern, Haiying Qin, Ira L. Kraft, Maryalice Stetler‐Stevenson, Constance M. Yuan, Jennifer Hwang, Yang Feng, Zhongyu Zhu, Dimiter S. Dimitrov, Nirali N. Shah, Terry J. Fry	2019	115
13	Chemical genomics reveals histone deacetylases are required for core regulatory transcription Nature Communications ·Berkley E. Gryder, Lei Wu, Girma M. Woldemichael, Silvia Pomella, Taylor R. Quinn, Paul M.C. Park, Abigail H. Cleveland, Benjamin Z. Stanton, Young Song, Rossella Rota, Olaf Wiest, Marielle E. Yohe, Jack F. Shern, Jun Qi, Javed Khan	2019	98
14	The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma Cancer Cell ·Matthew J. McBride, John L. Pulice, Hannah C. Beird, Davis R. Ingram, (unknown), Jack F. Shern, Gregory W. Charville, Jason L. Hornick, Robert Nakayama, Enrique Garcia-Rivera, Dejka M. Araujo, Wei‐Lien Wang, Jen-Wei Tsai, Michelle Yeagley, Andrew J. Wagner, P. Andrew Futreal, Javed Khan, Alexander J. Lazar, Cigall Kadoch	2018	173
15	Preclinical Development of Bivalent Chimeric Antigen Receptors Targeting Both CD19 and CD22 Molecular Therapy — Oncolytics ·Haiying Qin, Sneha Ramakrishna, Sang M. Nguyen, Thomas J. Fountaine, Eliseeva Op, Maryalice Stetler‐Stevenson, Constance M. Yuan, Waleed Haso, Jack F. Shern, Nirali N. Shah, Terry J. Fry	2018	200
16	Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib Clinical Cancer Research ·Ira L. Kraft, Srivandana Akshintala, David Ronald, Haiyan Lei, J. Senff, Eva Dombi, Seth M. Steinberg, Maya Lodish, Steven G. Waguespack, Oxana B. Kapustina, Elizabeth Fox, Frank M. Balis, Maria J. Merino, Paul S. Meltzer, John Glod, Jack F. Shern, Brigitte C. Widemann	2017	20
17	KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis Nature Medicine ·Meera Murgai, Wei Ju, Matthew G. Eason, Jessica Kline, Daniel W. Beury, Sabina Kaczanowska, Markku Miettinen, Michael J. Kruhlak, Haiyan Lei, Jack F. Shern, Olga A. Cherepanova, Gary K. Owens, Rosandra N. Kaplan	2017	185
18	Clonality and Evolutionary History of Rhabdomyosarcoma PLoS Genetics ·Li Chen, Jack F. Shern, Jun S. Wei, Marielle E. Yohe, Young Song, Laura Hurd, Hongling Liao, Daniel Catchpoole, Stephen X. Skapek, Frederic G. Barr, Douglas S. Hawkins, Javed Khan	2015	47
19	Munc18 Interacting Proteins Journal of Biological Chemistry ·Karen K. Hill, Yawei Li, 刘佳铭, Melissa McKay, Xinjun Zhu, Jack F. Shern, Enrique Torre, James J. Lah, Allan I. Levey, Richard Kahn	2003	71
20	ARL2 and BART Enter Mitochondria and Bind the Adenine Nucleotide Transporter Molecular Biology of the Cell ·J. Daniel Sharer, Jack F. Shern, Doç. Dr. Hasan Hüseyin Köşger, Douglas C. Wallace, Richard Kahn	2002	72

About Jack F. Shern

Jack F. Shern is a scholar working on Neurology, Pulmonary and Respiratory Medicine, Oncology, Cancer Research and Immunology, having authored 53 papers that have together received 3.4k indexed citations. Recurring topics across this work include Sarcoma Diagnosis and Treatment (24 papers), CAR-T cell therapy research (13 papers), Neuroblastoma Research and Treatments (11 papers), Protein Degradation and Inhibitors (11 papers), Immune Cell Function and Interaction (6 papers), Cancer Genomics and Diagnostics (6 papers), Neurofibromatosis and Schwannoma Cases (6 papers) and Cancer-related gene regulation (5 papers). The work is most often cited by research in Oncology (2.1k citations), Immunology (733 citations), Genetics (615 citations), Molecular Biology (1.5k citations) and Cancer Research (256 citations). Jack F. Shern has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Terry J. Fry, Waleed Haso, Crystal L. Mackall, Rosandra N. Kaplan, Meera Murgai, Javed Khan, Rimas J. Orentas, Maria Ingaramo, M. Eric Kohler and Kelsey M. Wanhainen. Their work appears in journals such as Clinical Cancer Research, Nature Communications, Journal of Biological Chemistry, Nature Medicine and Cell Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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