Darren E. Casteel

2.8k total citations
53 papers, 2.1k citations indexed

About

Darren E. Casteel is a scholar working on Molecular Biology, Physiology and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Darren E. Casteel has authored 53 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 43 papers in Molecular Biology, 20 papers in Physiology and 11 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Darren E. Casteel's work include Nitric Oxide and Endothelin Effects (17 papers), Receptor Mechanisms and Signaling (15 papers) and Protein Kinase Regulation and GTPase Signaling (12 papers). Darren E. Casteel is often cited by papers focused on Nitric Oxide and Endothelin Effects (17 papers), Receptor Mechanisms and Signaling (15 papers) and Protein Kinase Regulation and GTPase Signaling (12 papers). Darren E. Casteel collaborates with scholars based in United States, Germany and Canada. Darren E. Casteel's co-authors include Renate B. Pilz, Gerry R. Boss, Shunhui Zhuang, Tanima Gudi, Choel Kim, Hema Kalyanaraman, Raphaela Schwappacher, Brian T. Scott, Anna D. Dreilinger and Nissi Varki and has published in prestigious journals such as Journal of Biological Chemistry, Nature Communications and Blood.

In The Last Decade

Darren E. Casteel

52 papers receiving 2.1k citations

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Darren E. Casteel 1.4k 589 273 245 245 53 2.1k
Amee J. George 1.2k 0.9× 377 0.6× 214 0.8× 308 1.3× 127 0.5× 22 1.9k
Nobuo Kamada 1.2k 0.8× 429 0.7× 245 0.9× 419 1.7× 408 1.7× 38 2.2k
Xiaojun Zhu 1.9k 1.3× 246 0.4× 258 0.9× 204 0.8× 292 1.2× 58 2.5k
Kay Barnes 1.0k 0.7× 602 1.0× 186 0.7× 259 1.1× 99 0.4× 36 2.0k
Kenneth P. Chepenik 917 0.6× 427 0.7× 205 0.8× 232 0.9× 252 1.0× 36 1.9k
Cristina Murga 2.5k 1.8× 439 0.7× 285 1.0× 389 1.6× 116 0.5× 52 3.2k
Eric Boursier 1.6k 1.1× 342 0.6× 171 0.6× 234 1.0× 131 0.5× 2 2.4k
Leonard P. Adam 1.2k 0.9× 435 0.7× 444 1.6× 98 0.4× 86 0.4× 52 2.0k
Lisa M. Ooms 1.6k 1.1× 304 0.5× 95 0.3× 250 1.0× 199 0.8× 47 2.4k
Richard T. Waldron 2.0k 1.4× 258 0.4× 164 0.6× 599 2.4× 192 0.8× 63 3.2k

Countries citing papers authored by Darren E. Casteel

Since Specialization
Citations

This map shows the geographic impact of Darren E. Casteel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darren E. Casteel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darren E. Casteel more than expected).

Fields of papers citing papers by Darren E. Casteel

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darren E. Casteel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darren E. Casteel. The network helps show where Darren E. Casteel may publish in the future.

Co-authorship network of co-authors of Darren E. Casteel

This figure shows the co-authorship network connecting the top 25 collaborators of Darren E. Casteel. A scholar is included among the top collaborators of Darren E. Casteel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Darren E. Casteel. Darren E. Casteel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kalyanaraman, Hema, Shyamsundar Pal China, Darren E. Casteel, & Renate B. Pilz. (2025). Crosstalk between androgen receptor and protein kinase G signaling in bone: implications for osteoporosis therapy. Trends in Pharmacological Sciences. 46(3). 279–294. 1 indexed citations
2.
Kalyanaraman, Hema, Darren E. Casteel, Shyamsundar Pal China, et al.. (2024). A plasma membrane–associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells. Science Signaling. 17(821). eadi7861–eadi7861. 4 indexed citations
3.
Kalyanaraman, Hema, Darren E. Casteel, John Tat, et al.. (2023). The Antioxidant/Nitric Oxide-Quenching Agent Cobinamide Prevents Aortic Disease in a Mouse Model of Marfan Syndrome. JACC Basic to Translational Science. 9(1). 46–62. 2 indexed citations
4.
Hu, Tingfei, et al.. (2022). PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells. Journal of Biological Chemistry. 298(8). 102175–102175.
5.
Kalyanaraman, Hema, Shyamsundar Pal China, Darren E. Casteel, et al.. (2020). Protein Kinase G2 Is Essential for Skeletal Homeostasis and Adaptation to Mechanical Loading in Male but Not Female Mice. Journal of Bone and Mineral Research. 38(1). 171–185. 7 indexed citations
6.
Hu, Tingfei, et al.. (2020). A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP. Journal of Biological Chemistry. 295(30). 10394–10405. 9 indexed citations
7.
Dhar, Debanjan, Hui Chen, Shunhui Zhuang, et al.. (2020). Metabolic interaction between amino acid deprivation and cisplatin synergistically reduces phosphoribosyl-pyrophosphate and augments cisplatin cytotoxicity. Scientific Reports. 10(1). 19907–19907. 7 indexed citations
8.
Sankaran, Banumathi, et al.. (2018). Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46. Journal of Biological Chemistry. 293(28). 10985–10992. 7 indexed citations
9.
10.
Kim, Jeong Joo, Robin Lorenz, Stefan T. Arold, et al.. (2016). Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation. Structure. 24(5). 710–720. 32 indexed citations
11.
Reger, Albert S., Shrenik Mehta, Keizo Yuasa, et al.. (2014). Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions. Journal of Biological Chemistry. 289(37). 25393–25403. 17 indexed citations
12.
Guo, Dongchuan, Ellen S. Regalado, Darren E. Casteel, et al.. (2013). Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections. The American Journal of Human Genetics. 93(2). 398–404. 162 indexed citations
13.
Osborne, Brent W., Jian Wu, Christian K. Nickl, et al.. (2011). Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication. Structure. 19(9). 1317–1327. 50 indexed citations
14.
Casteel, Darren E., et al.. (2010). A Crystal Structure of the Cyclic GMP-dependent Protein Kinase Iβ Dimerization/Docking Domain Reveals Molecular Details of Isoform-specific Anchoring*. Journal of Biological Chemistry. 285(43). 32684–32688. 26 indexed citations
15.
Casteel, Darren E., Shunhui Zhuang, Ying Zeng, et al.. (2009). A DNA Polymerase-α·Primase Cofactor with Homology to Replication Protein A-32 Regulates DNA Replication in Mammalian Cells. Journal of Biological Chemistry. 284(9). 5807–5818. 124 indexed citations
16.
Casteel, Darren E., Tong Zhang, Shunhui Zhuang, & Renate B. Pilz. (2008). cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity. Cellular Signalling. 20(7). 1392–1399. 33 indexed citations
17.
Zhang, Tong, Shunhui Zhuang, Darren E. Casteel, et al.. (2007). A Cysteine-rich LIM-only Protein Mediates Regulation of Smooth Muscle-specific Gene Expression by cGMP-dependent Protein Kinase. Journal of Biological Chemistry. 282(46). 33367–33380. 28 indexed citations
18.
Chen, Yongchang, Shunhui Zhuang, Darren E. Casteel, et al.. (2003). Synergism between Calcium and Cyclic GMP in Cyclic AMP Response Element-Dependent Transcriptional Regulation Requires Cooperation between CREB and C/EBP-β. Molecular and Cellular Biology. 23(12). 4066–4082. 48 indexed citations
19.
Gudi, Tanima, Jeffrey C. Chen, Darren E. Casteel, et al.. (2002). cGMP-dependent Protein Kinase Inhibits Serum-response Element-dependent Transcription by Inhibiting Rho Activation and Functions. Journal of Biological Chemistry. 277(40). 37382–37393. 72 indexed citations
20.
Casteel, Darren E., Shunhui Zhuang, Tanima Gudi, et al.. (2002). cGMP-dependent Protein Kinase Iβ Physically and Functionally Interacts with the Transcriptional Regulator TFII-I. Journal of Biological Chemistry. 277(35). 32003–32014. 54 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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