Darren E. Casteel

2.8k total citations
53 papers, 2.1k citations indexed

About

Darren E. Casteel is a scholar working on Molecular Biology, Physiology and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Darren E. Casteel has authored 53 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 43 papers in Molecular Biology, 20 papers in Physiology and 11 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Darren E. Casteel's work include Nitric Oxide and Endothelin Effects (17 papers), Receptor Mechanisms and Signaling (15 papers) and Protein Kinase Regulation and GTPase Signaling (12 papers). Darren E. Casteel is often cited by papers focused on Nitric Oxide and Endothelin Effects (17 papers), Receptor Mechanisms and Signaling (15 papers) and Protein Kinase Regulation and GTPase Signaling (12 papers). Darren E. Casteel collaborates with scholars based in United States, Germany and Canada. Darren E. Casteel's co-authors include Renate B. Pilz, Gerry R. Boss, Shunhui Zhuang, Tanima Gudi, Choel Kim, Hema Kalyanaraman, Raphaela Schwappacher, Wolfgang Dillmann, Brian T. Scott and Friederike C. von Lintig and has published in prestigious journals such as Journal of Biological Chemistry, Nature Communications and Blood.

In The Last Decade

Darren E. Casteel

52 papers receiving 2.1k citations

Peers

Countries citing papers authored by Darren E. Casteel

Since Specialization

Citations

This map shows the geographic impact of Darren E. Casteel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darren E. Casteel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darren E. Casteel more than expected).

Fields of papers citing papers by Darren E. Casteel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darren E. Casteel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darren E. Casteel. The network helps show where Darren E. Casteel may publish in the future.

Co-authorship network of co-authors of Darren E. Casteel

This figure shows the co-authorship network connecting the top 25 collaborators of Darren E. Casteel. A scholar is included among the top collaborators of Darren E. Casteel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Darren E. Casteel. Darren E. Casteel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Crosstalk between androgen receptor and protein kinase G signaling in bone: implications for osteoporosis therapy 2025 ·Trends in Pharmacological Sciences ·Hema Kalyanaraman, Shyamsundar Pal China, Darren E. Casteel, Renate B. Pilz	1
2	A plasma membrane–associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells 2024 ·Science Signaling ·Hema Kalyanaraman, Darren E. Casteel, Shyamsundar Pal China, Shunhui Zhuang, Gerry R. Boss, Renate B. Pilz	4
3	PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells 2022 ·Journal of Biological Chemistry ·(unknown), Tingfei Hu, Renate B. Pilz, Darren E. Casteel	0
4	Bladder Cancer Invasion Is Mediated by Mammalian Target of Rapamycin Complex 2–Driven Regulation of Nitric Oxide and Invadopodia Formation 2021 ·American Journal Of Pathology ·Divya Sahu, Jianya Huan, Huawei Wang, Debashis Sahoo, Darren E. Casteel, Richard Klemke, Gerry R. Boss, Donna E. Hansel	10
5	A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP 2020 ·Journal of Biological Chemistry ·(unknown), (unknown), Tingfei Hu, (unknown), Sheng Li, Choel Kim, Renate B. Pilz, Darren E. Casteel	9
6	Phosphorylation of protein kinase A (PKA) regulatory subunit RIα by protein kinase G (PKG) primes PKA for catalytic activity in cells 2018 ·Journal of Biological Chemistry ·Kristofer J. Haushalter, Darren E. Casteel, (unknown), Eduard Stefan, Hemal H. Patel, Susan S. Taylor	24
7	Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase–Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase 2016 ·American Journal Of Pathology ·Divya Sahu, Sounak Gupta, Andrew M. Hau, Kazufumi Nakashima, (unknown), Stephen Searles, Paul Elson, John S. Bomalaski, Darren E. Casteel, Gerry R. Boss, Donna E. Hansel	25
8	Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation 2016 ·Structure ·Jeong Joo Kim, Robin Lorenz, Stefan T. Arold, Albert S. Reger, Banumathi Sankaran, Darren E. Casteel, Friedrich W. Herberg, Choel Kim	32
9	Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions 2014 ·Journal of Biological Chemistry ·Albert S. Reger, (unknown), (unknown), (unknown), Shrenik Mehta, Keizo Yuasa, Alan Z. Liu, Darren E. Casteel, Choel Kim	17
10	Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections 2013 ·The American Journal of Human Genetics ·Dongchuan Guo, Ellen S. Regalado, Darren E. Casteel, Regie Lyn P. Santos‐Cortez, Limin Gong, Jeong Joo Kim, Sarah Dyack, (unknown), Guijuan Chang, Guillaume Jondeau, Cathérine Boileau, Joseph S. Coselli, Zhenyu Li, Suzanne M. Leal, Jay Shendure, Mark J. Rieder, Michael J. Bamshad, Deborah A. Nickerson, Choel Kim, Dianna M. Milewicz	162
11	Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I 2013 ·Structure ·Gilbert Y. Huang, Jeong Joo Kim, Albert S. Reger, Robin Lorenz, (unknown), Chi Zhao, Darren E. Casteel, Daniela Bertinetti, Bryan VanSchouwen, Rajeevan Selvaratnam, J. W. Pflugrath, Banumathi Sankaran, Giuseppe Melacini, Friedrich W. Herberg, Choel Kim	53
12	Rho Isoform-specific Interaction with IQGAP1 Promotes Breast Cancer Cell Proliferation and Migration 2012 ·Journal of Biological Chemistry ·Darren E. Casteel, Stephanie Turner, Raphaela Schwappacher, Hema Rangaswami, (unknown), Shunhui Zhuang, Gerry R. Boss, Renate B. Pilz	56
13	Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication 2011 ·Structure ·Brent W. Osborne, Jian Wu, (unknown), Christian K. Nickl, Banumathi Sankaran, Darren E. Casteel, Virgil L. Woods, Alexandr P. Kornev, Susan S. Taylor, Wolfgang R. Dostmann	50
14	A DNA Polymerase-α·Primase Cofactor with Homology to Replication Protein A-32 Regulates DNA Replication in Mammalian Cells 2009 ·Journal of Biological Chemistry ·Darren E. Casteel, Shunhui Zhuang, Ying Zeng, Fred W. Perrino, Gerry R. Boss, Mehran Goulian, Renate B. Pilz	124
15	cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity 2008 ·Cellular Signalling ·Darren E. Casteel, Tong Zhang, Shunhui Zhuang, Renate B. Pilz	33
16	Nitric Oxide Inhibits Mammalian Methylmalonyl-CoA Mutase 2005 ·Journal of Biological Chemistry ·(unknown), Vijay S. Sharma, Darren E. Casteel, Virgil L. Woods, Renate B. Pilz, Gerry R. Boss	29
17	Identification of the Interface between cGMP-dependent Protein Kinase Iβ and Its Interaction Partners TFII-I and IRAG Reveals a Common Interaction Motif 2005 ·Journal of Biological Chemistry ·Darren E. Casteel, Gerry R. Boss, Renate B. Pilz	28
18	Synergism between Calcium and Cyclic GMP in Cyclic AMP Response Element-Dependent Transcriptional Regulation Requires Cooperation between CREB and C/EBP-β 2003 ·Molecular and Cellular Biology ·Yongchang Chen, Shunhui Zhuang, (unknown), Darren E. Casteel, Tanima Gudi, Gerry R. Boss, Renate B. Pilz	48
19	cGMP-dependent Protein Kinase Iβ Physically and Functionally Interacts with the Transcriptional Regulator TFII-I 2002 ·Journal of Biological Chemistry ·Darren E. Casteel, Shunhui Zhuang, Tanima Gudi, Julian W. Tang, (unknown), Stephen Desiderio, Renate B. Pilz	54
20	cGMP-dependent Protein Kinase Inhibits Serum-response Element-dependent Transcription by Inhibiting Rho Activation and Functions 2002 ·Journal of Biological Chemistry ·Tanima Gudi, Jeffrey C. Chen, Darren E. Casteel, Tammy M. Seasholtz, Gerry R. Boss, Renate B. Pilz	72

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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