Jason R. Spence

22.4k total citations · 8 hit papers
143 papers, 12.4k citations indexed

About

Jason R. Spence is a scholar working on Molecular Biology, Surgery and Genetics. According to data from OpenAlex, Jason R. Spence has authored 143 papers receiving a total of 12.4k indexed citations (citations by other indexed papers that have themselves been cited), including 84 papers in Molecular Biology, 57 papers in Surgery and 39 papers in Genetics. Recurrent topics in Jason R. Spence's work include Renal and related cancers (34 papers), Cancer Cells and Metastasis (29 papers) and Neonatal Respiratory Health Research (28 papers). Jason R. Spence is often cited by papers focused on Renal and related cancers (34 papers), Cancer Cells and Metastasis (29 papers) and Neonatal Respiratory Health Research (28 papers). Jason R. Spence collaborates with scholars based in United States, United Kingdom and Germany. Jason R. Spence's co-authors include James M. Wells, Christopher N. Mayhew, David R. Hill, Noah F. Shroyer, Alyssa J. Miller, Sha Huang, Melinda Nagy, Aaron M. Zorn, Jefferson E. Vallance and Briana R. Dye and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Jason R. Spence

141 papers receiving 12.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

2010 1.4k citations Jason R. Spence, Aaron M. Zorn et al. profile →
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids

2014 718 citations Yu-Hwai Tsai, Jason R. Spence et al. profile →
In vitro generation of human pluripotent stem cell derived lung organoids

2015 612 citations David R. Hill, Yu-Hwai Tsai et al. profile →
Synthetic hydrogels for human intestinal organoid generation and colonic wound repair

2017 430 citations Miguel Quirós, Priya H. Dedhia et al. profile →
An in vivo model of human small intestine using pluripotent stem cells

2014 422 citations Maxime M. Mahé, Nambirajan Sundaram et al. profile →
Generation of lung organoids from human pluripotent stem cells in vitro

2019 297 citations Alyssa J. Miller, Daysha Ferrer-Torres et al. profile →
Human distal lung maps and lineage hierarchies reveal a bipotent progenitor

2022 165 citations Ansley S. Conchola, Jason R. Spence et al. profile →
A human liver organoid screening platform for DILI risk prediction

2023 108 citations Charles J. Zhang, Sha Huang et al. profile →

Peers

Countries citing papers authored by Jason R. Spence

Since Specialization

Citations

This map shows the geographic impact of Jason R. Spence's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jason R. Spence with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jason R. Spence more than expected).

Fields of papers citing papers by Jason R. Spence

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jason R. Spence. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jason R. Spence. The network helps show where Jason R. Spence may publish in the future.

Co-authorship network of co-authors of Jason R. Spence

This figure shows the co-authorship network connecting the top 25 collaborators of Jason R. Spence. A scholar is included among the top collaborators of Jason R. Spence based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jason R. Spence. Jason R. Spence is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function 2024 ·Molecular Cancer Research ·Paramita Ray, Sangeeta Jaiswal, Daysha Ferrer-Torres, (unknown), Derek J. Nancarrow, (unknown), (unknown), (unknown), (unknown), Dafydd G. Thomas, Jason R. Spence, Matthias C. Truttmann, Kiran H. Lagisetty, Theodore S. Lawrence, Thomas D. Wang, David G. Beer, Dipankar Ray	0
2	Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung 2023 ·npj Regenerative Medicine ·Tristan Frum, Peggy P. Hsu, (unknown), Ansley S. Conchola, Charles J. Zhang, (unknown), (unknown), (unknown), (unknown), Ian A. Glass, Jonathan Z. Sexton, Jason R. Spence	6
3	In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice 2023 ·Nature Biotechnology ·Carine Bouffi, Kathryn A. Wikenheiser‐Brokamp, Praneet Chaturvedi, Nambirajan Sundaram, (unknown), Mark Wunderlich, Nicole Brown, Janet F. Staab, Rachel Latanich, Nicholas C. Zachos, Emily M. Holloway, Maxime M. Mahé, Holly M. Poling, (unknown), (unknown), Jason R. Spence, James C. Mulloy, Aaron M. Zorn, James M. Wells, Michael A. Helmrath	76
4	Stable iPSC-derived NKX2-1+ lung bud tip progenitor organoids give rise to airway and alveolar cell types 2022 ·Development ·(unknown), Ansley S. Conchola, (unknown), Zhiwei Xiao, Tristan Frum, (unknown), (unknown), Charlie J. Childs, Yu-Hwai Tsai, Emily M. Holloway, Sha Huang, John E. Mahoney, Idse Heemskerk, Jason R. Spence	22
5	Vertical sleeve gastrectomy induces enteroendocrine cell differentiation of intestinal stem cells through bile acid signaling 2022 ·JCI Insight ·Ki‐Suk Kim, Bailey C. E. Peck, Yu-Han Hung, Kieran Koch‐Laskowski, (unknown), Priya H. Dedhia, Jason R. Spence, Randy J. Seeley, Praveen Sethupathy, Darleen A. Sandoval	12
6	Salmonella enterica Serovar Typhimurium SPI-1 and SPI-2 Shape the Global Transcriptional Landscape in a Human Intestinal Organoid Model System 2021 ·mBio ·(unknown), Basel H. Abuaita, (unknown), David R. Hill, (unknown), (unknown), (unknown), (unknown), Christiane E. Wobus, Jason R. Spence, Vincent B. Young, Mary O’Riordan	21
7	Comparative transcriptional profiling of the early host response to infection by typhoidal and non-typhoidal Salmonella serovars in human intestinal organoids 2021 ·PLoS Pathogens ·Basel H. Abuaita, (unknown), (unknown), David R. Hill, Sha Huang, (unknown), (unknown), (unknown), Christiane E. Wobus, Jason R. Spence, Vincent B. Young, Mary O’Riordan	19
8	Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells 2021 ·Nature Metabolism ·Andrew J. Schwartz, Joshua Goyert, Sumeet Solanki, Samuel A. Kerk, Brandon Chen, (unknown), Peggy P. Hsu, T. Brian, Rashi Singhal, Michael K. Dame, Ho‐Joon Lee, Jason R. Spence, Samira Lakhal‐Littleton, Matthew G. Vander Heiden, Costas A. Lyssiotis, Xiang Xue, Yatrik M. Shah	79
9	Biomarkers for the Prediction and Diagnosis of Fibrostenosing Crohn’s Disease: A Systematic Review 2021 ·Clinical Gastroenterology and Hepatology ·Calen A. Steiner, Jeffrey Berinstein, Jeremy Louissaint, Peter Higgins, Jason R. Spence, Carol Shannon, Cathy Lu, Ryan W. Stidham, Joel G. Fletcher, David H. Bruining, Brian G. Feagan, Vipul Jairath, Mark E. Baker, Dominik Bettenworth, Florian Rieder	40
10	Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model 2020 ·Nucleic Acids Research ·Yu-Han Hung, Sha Huang, Michael K. Dame, Qianhui Yu, Qing Yu, Yi Arial Zeng, J. Gray Camp, Jason R. Spence, Praveen Sethupathy	5
11	RYK-mediated filopodial pathfinding facilitates midgut elongation 2020 ·Development ·Sha Wang, (unknown), (unknown), (unknown), Yu-Hwai Tsai, Lisa Cameron, (unknown), Jason R. Spence, Katherine D. Walton, Steven A. Stacker, Deborah L. Gumucio, Terry Lechler	5
12	The Lumen of Human Intestinal Organoids Poses Greater Stress to Bacteria Compared to the Germ-Free Mouse Intestine: Escherichia coli Deficient in RpoS as a Colonization Probe 2020 ·mSphere ·(unknown), (unknown), David R. Hill, Sha Huang, (unknown), Jason R. Spence, Vincent B. Young	7
13	Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells 2020 ·Frontiers in Cell and Developmental Biology ·Ryan F. Townshend, Yue Shao, Sicong Wang, (unknown), Sajedeh Nasr Esfahani, Jason R. Spence, K. Sue O’Shea, Jianping Fu, Deborah L. Gumucio, K Taniguchi	14
14	The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development 2019 ·Development ·Namit Kumar, Yu-Hwai Tsai, Lei Chen, Anbo Zhou, Kushal K. Banerjee, Madhurima Saxena, Sha Huang, Natalie H. Toke, Jinchuan Xing, Ramesh A. Shivdasani, Jason R. Spence, Michael P. Verzi	45
15	Single-cell RNA sequencing identifies TGF-β as a key regenerative cue following LPS-induced lung injury 2019 ·JCI Insight ·Kent Riemondy, (unknown), Peng Jiang, Elizabeth F. Redente, Austin E. Gillen, Rui Fu, Alyssa J. Miller, Jason R. Spence, Anthony N. Gerber, Jay R. Hesselberth, Rachel L. Zemans	99
16	Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney 2018 ·Development ·Rajasree Menon, Edgar A. Otto, (unknown), Jian Zhou, Zidong Zhang, Euisik Yoon, Yu‐Chih Chen, Olga G. Troyanskaya, Jason R. Spence, Matthias Kretzler, Cristina Cebrián	96
17	Real-time Measurement of Epithelial Barrier Permeability in Human Intestinal Organoids 2017 ·Journal of Visualized Experiments ·David R. Hill, Sha Huang, Yu-Hwai Tsai, Jason R. Spence, Vincent B. Young	35
18	Real-time Measurement of Epithelial Barrier Permeability in Human Intestinal Organoids 2017 ·Journal of Visualized Experiments ·David R. Hill, Sha Huang, Yu-Hwai Tsai, Jason R. Spence, Vincent B. Young	17
19	The Williams syndrome prosociality gene GTF2I mediates oxytocin reactivity and social anxiety in a healthy population 2017 ·Biology Letters ·(unknown), Jason R. Spence, (unknown), Neil V. Watson, Bernard J. Crespi	23
20	Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling 2017 ·Journal of Clinical Investigation ·Miguel Quirós, Hikaru Nishio, Philipp Neumann, Dorothée Siuda, Jennifer Brazil, Verónica Azcutia, Roland Hilgarth, Monique N. O’Leary, Vicky García‐Hernández, Giovanna Leoni, Mingli Feng, (unknown), Holly C. Williams, Priya H. Dedhia, Christian Gerner‐Smidt, Jason R. Spence, Charles A. Parkos, Timothy L. Denning, Asma Nusrat	160

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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