André Guillouzo

12.6k citations

192 papers · 10.0k indexed · 2 hit papers · h-index 56

Impact in

Pharmacology top 0.02%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
Hepatology top 0.2%
- Liver physiology and pathology

Papers in

Pharmacology 85
- Pharmacogenetics and Drug Metabolism 68
- Drug-Induced Hepatotoxicity and Protection 46
Hepatology 30
- Liver physiology and pathology 26

Co-authors: Christiane Guguen‐Guillouzo Fabrice Morel Olivier Fardel Denise Glaise Caroline Aninat Sophie Langouët Christophe Chesné Valérie Lecureur
Journals: Hepatology (14 papers)Biochemical and Biophysical Research Communications (14 papers)Biochemical Pharmacology (14 papers)FEBS Letters (11 papers)Toxicology in Vitro (10 papers)
Partner nations: France United States Germany

In The Last Decade

André Guillouzo

192 papers receiving 9.7k citations

Hit Papers

align trajectories log scale

Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies 2007 · 530 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2007 Drug Metabolism Reviews
2005 Drug Metabolism and Disposition

Peers

Countries citing papers authored by André Guillouzo

Since Specialization

Citations

This map shows the geographic impact of André Guillouzo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by André Guillouzo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites André Guillouzo more than expected).

Fields of papers citing papers by André Guillouzo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by André Guillouzo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by André Guillouzo. The network helps show where André Guillouzo may publish in the future.

Co-authorship network

The 25 scholars most cited alongside André Guillouzo, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with André Guillouzo Line = papers co-authored together André Guillouzo links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A Dynamic Mathematical Model of Bile Acid Clearance in HepaRG Cells Toxicological Sciences ·Daniel Kaschek, Ahmad Sharanek, André Guillouzo, Jens Timmer, Richard Weaver	2017	6
2	Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes Toxicological Sciences ·Guan-Chao Zhao, Ahmad Sharanek, Audrey Burban, Ruoya Li, Rémy Le Guével, Ziad Abdel‐Razzak, Bruno Stieger, Christiane Guguen‐Guillouzo, André Guillouzo	2015	60
3	Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure Toxicology in Vitro ·Muslim, C. Parmentier, L. Blottière, Rozenn Jossé, Eliane Alexandre, MM Kielbowicz, Philip Hewitt, Stefan O. Mueller, André Guillouzo, Lysiane Richert, J.C.H. van Eijkeren, Joop L. M. Hermens, Bas J. Blaauboer	2014	22
4	Differential toxic effects of azathioprine, 6-mercaptopurine and 6-thioguanine on human hepatocytes Toxicology in Vitro ·Ashleigh Bullot, Sophie Langouët, Sophie Mills, Dhaneswara, André Guillouzo, Fabrice Morel	2007	65
5	Gene and Protein Characterization of the Human Glutathione S-Transferase Kappa and Evidence for a Peroxisomal Localization Journal of Biological Chemistry ·Fabrice Morel, Claudine Rauch, Ashleigh Bullot, Amélie Piton, Nathalie Théret, Brian Coles, André Guillouzo	2004	125
6	Blockage of Multidrug Resistance-Associated Proteins Potentiates the Inhibitory Effects of Arsenic Trioxide on CYP1A1 Induction by Polycyclic Aromatic Hydrocarbons Journal of Pharmacology and Experimental Therapeutics ·Laurent Vernhet, Nathalie Allain, Marc Le Vée, Fabrice Morel, André Guillouzo, Olivier Fardel	2003	32
7	Expression of cytochromes P450 3A in mouse lung: effects of dexamethasone and pregnenolone 16α-carbonitrile Archives of Toxicology ·Jesús Alberto Pérez Mesa, Alain Fautrel, André Guillouzo, Nelly Frossard, Françoise Pons	2002	12
8	Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2 Mutation research. Fundamental and molecular mechanisms of mutagenesis ·Robert J. Turesky, F. Peter Guengerich, André Guillouzo, Sophie Langouët	2002	69
9	Unaltered expression of multidrug resistance transporters in polycyclic aromatic hydrocarbon-resistant rat liver cells Toxicology ·Léa Payen, Arnaud Courtois, Sophie Langouët, André Guillouzo, Olivier Fardel	2001	14
10	Characterization and inhibition by a wide range of xenobiotics of organic anion excretion by primary human hepatocytes Biochemical Pharmacology ·Léa Payen, Arnaud Courtois, Jean‐Pierre Campion, André Guillouzo, Olivier Fardel	2000	63
11	Inhibition of multidrug resistance-associated protein (MRP) activity by rifampicin in human multidrug-resistant lung tumor cells Cancer Letters ·Arnaud Courtois, Léa Payen, Laurent Vernhet, Elisabeth G.E. de Vries, André Guillouzo, Olivier Fardel	1999	24
12	Endotoxin Suppresses the Oltipraz–Mediated Induction of Major Hepatic Glutathione Transferases and Cytochromes P450 in the Rat Hepatology ·Karine Mahéo, Fabrice Morel, Jocelyne Antras‐Ferry, Sophie Langouët, Fabienne Desmots, Laurent Corcos, André Guillouzo	1998	25
13	Inhibition by perhexiline of oxidative phosphorylation and the β-oxidation of fatty acids: Possible role in pseudoalcoholic liver lesions Hepatology ·D Deschamps, 昭荒木, C Fisch, Bernard Fromenty, André Guillouzo, Dominique Pessayre	1994	76
14	The antiprogestatin drug RU 486 potentiates doxorubicin cytotoxicity in multidrug resistant cells through inhibition of P‐glycoprotein function FEBS Letters ·Valérie Lecureur, Olivier Fardel, André Guillouzo	1994	48
15	Distribution and origin of the basement membrane component perlecan in rat liver and primary hepatocyte culture. PubMed ·Pierre‐Yves Rescan, Olivier Loréal, John R. Hassell, Yoshihiko Yamada, André Guillouzo, Bruno Clément	1993	52
16	Distribution and cellular origin of collagen VI during development and in cirrhosis Gastroenterology ·Olivier Loréal, Bruno Clément, Detlef Schuppan, Pierre‐Yves Rescan, Maryvonne Rissel, André Guillouzo	1992	41
17	Differential expression of laminin chains in hepatic lipocytes FEBS Letters ·Olivier Loréal, Françoise Levavasseur, Pierre‐Yves Rescan, Yoshihiko Yamada, André Guillouzo, Bruno Clément	1991	20
18	Transforming growth-factor-β (TGF-β) inhibits albumin synthesis in normal human hepatocytes and in hepatoma HepG2 cells Biochemical and Biophysical Research Communications ·Nathalie Busso, Christophe Chesné, Ana María Abril Gallego, Fabrice Morel, André Guillouzo	1990	23
19	Hepatocytes may produce laminin in fibrotic liver and in primary culture Hepatology ·Bruno Clément, Pierre‐Yves Rescan, Georges Baffet, Olivier Loréal, Theresa Cragen Draherp, Jean‐Pierre Campion, André Guillouzo	1988	78
20	Modifications of Phosphoproteins and Protein Kinases Occurring with in vitro Aging of Cultured Human Cells Gerontology ·Axel Kahn, Miguel Sicart, André Guillouzo, Dominique Cottreau, Georges Baffet, 章熙锋, Jean‐Claude Dreyfus	1982	10

About André Guillouzo

André Guillouzo is a scholar working on Pharmacology, Hepatology, Oncology, Cancer Research and Clinical Biochemistry, having authored 192 papers that have together received 10.0k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (73 papers), Pharmacogenetics and Drug Metabolism (68 papers), Drug-Induced Hepatotoxicity and Protection (46 papers), Liver physiology and pathology (26 papers), Liver Disease Diagnosis and Treatment (22 papers), Genomics, phytochemicals, and oxidative stress (20 papers), Carcinogens and Genotoxicity Assessment (15 papers) and Glutathione Transferases and Polymorphisms (15 papers). The work is most often cited by research in Pharmacology (3.3k citations), Hepatology (2.4k citations), Oncology (2.6k citations), Cancer Research (934 citations) and Biochemistry (426 citations). André Guillouzo has collaborated with scholars based in France, United States and Germany. Frequent co-authors include Christiane Guguen‐Guillouzo, Fabrice Morel, Olivier Fardel, Denise Glaise, Caroline Aninat, Sophie Langouët, Christophe Chesné, Valérie Lecureur, Bruno Clément and Anne Corlu. Their work appears in journals such as Hepatology, Biochemical and Biophysical Research Communications, Biochemical Pharmacology, FEBS Letters and Toxicology in Vitro.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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