Cliff J. Luke

3.8k total citations · 1 hit paper
53 papers, 2.9k citations indexed

About

Cliff J. Luke is a scholar working on Molecular Biology, Aging and Cancer Research. According to data from OpenAlex, Cliff J. Luke has authored 53 papers receiving a total of 2.9k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 18 papers in Aging and 16 papers in Cancer Research. Recurrent topics in Cliff J. Luke's work include Genetics, Aging, and Longevity in Model Organisms (18 papers), Protease and Inhibitor Mechanisms (16 papers) and Peptidase Inhibition and Analysis (5 papers). Cliff J. Luke is often cited by papers focused on Genetics, Aging, and Longevity in Model Organisms (18 papers), Protease and Inhibitor Mechanisms (16 papers) and Peptidase Inhibition and Analysis (5 papers). Cliff J. Luke collaborates with scholars based in United States, Australia and United Kingdom. Cliff J. Luke's co-authors include Gary A. Silverman, Stephen C. Pak, James C. Whisstock, Phillip I. Bird, James A. Irving, Paul Coughlin, Eileen Remold‐O’Donnell, Richard W. Moyer, Peter G.W. Gettins and Guy S. Salvesen and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Cliff J. Luke

52 papers receiving 2.9k citations

Hit Papers

The Serpins Are an Expanding Superfamily of Structurally ... 2001 2026 2009 2017 2001 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins
    2001 1.0k citations Gary A. Silverman, Phillip I. Bird et al. Journal of Biological Chemistry profile →

Peers

Cliff J. Luke
Jun Yasuda Japan
Gary A. Silverman United States
Beverly A. Mock United States
Masaaki Oyama Japan
Susana González Spain
Hiroko Kozuka‐Hata Japan
Esther Caparrós Spain
Kaoru Tominaga Japan
Mariola J. Edelmann United States
Tommy Alain Canada
Jun Yasuda Japan
Cliff J. Luke
Citations per year, relative to Cliff J. Luke Cliff J. Luke (= 1×) peers Jun Yasuda

Countries citing papers authored by Cliff J. Luke

Since Specialization
Citations

This map shows the geographic impact of Cliff J. Luke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cliff J. Luke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cliff J. Luke more than expected).

Fields of papers citing papers by Cliff J. Luke

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cliff J. Luke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cliff J. Luke. The network helps show where Cliff J. Luke may publish in the future.

Co-authorship network of co-authors of Cliff J. Luke

This figure shows the co-authorship network connecting the top 25 collaborators of Cliff J. Luke. A scholar is included among the top collaborators of Cliff J. Luke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Cliff J. Luke. Cliff J. Luke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Luke, Cliff J., Lila S. Nolan, Qingqing Gong, et al.. (2023). Microfluidic device facilitates in vitro modeling of human neonatal necrotizing enterocolitis–on-a-chip. JCI Insight. 8(8). 21 indexed citations
2.
Yang, Fan, M Wong, R.W. Johnson, et al.. (2023). Staphylococcus aureus α-toxin impairs early neutrophil localization via electrogenic disruption of store-operated calcium entry. Cell Reports. 42(11). 113394–113394. 7 indexed citations
3.
Wang, Songyan, Cliff J. Luke, Stephen C. Pak, et al.. (2022). SERPINB3 (SCCA1) inhibits cathepsin L and lysoptosis, protecting cervical cancer cells from chemoradiation. Communications Biology. 5(1). 46–46. 18 indexed citations
4.
Mihi, Belgacem, Qingqing Gong, Lila S. Nolan, et al.. (2021). Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration. Cell Reports Medicine. 2(6). 100320–100320. 40 indexed citations
5.
Wambach, Jennifer, Ping Yang, Daniel Wegner, et al.. (2020). Functional Genomics of ABCA3 Variants. American Journal of Respiratory Cell and Molecular Biology. 63(4). 436–443. 17 indexed citations
6.
Moreno-Ibarra, Marco, Huiyan Huang, Hyori Kim, et al.. (2019). CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans. PLoS ONE. 14(3). e0214257–e0214257. 12 indexed citations
7.
Markovina, Stephanie, Songyan Wang, Lauren E. Henke, et al.. (2017). Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer. British Journal of Cancer. 118(1). 72–78. 55 indexed citations
8.
Shi, Shujie, Cliff J. Luke, Mark T. Miedel, Gary A. Silverman, & Thomas R. Kleyman. (2016). Activation of the Caenorhabditis elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit. Journal of Biological Chemistry. 291(27). 14012–14022. 15 indexed citations
9.
Cummings, Erin E., Linda P. O’Reilly, Mark T. Miedel, et al.. (2015). The Aggregation-Prone Intracellular Serpin SRP-2 Fails to Transit the ER inCaenorhabditis elegans. Genetics. 200(1). 207–219. 1 indexed citations
10.
Miedel, Mark T., Xuemei Zeng, Nathan A. Yates, Gary A. Silverman, & Cliff J. Luke. (2014). Isolation of serpin-interacting proteins in C. elegans using protein affinity purification. Methods. 68(3). 536–541. 3 indexed citations
11.
Long, Olivia S., Joon Hyeok Kwak, Cliff J. Luke, et al.. (2014). A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover. Human Molecular Genetics. 23(19). 5109–5122. 24 indexed citations
12.
Silverman, Gary A., et al.. (2013). A Small Conductance Calcium-Activated K+ Channel in C. elegans, KCNL-2, Plays a Role in the Regulation of the Rate of Egg-Laying. PLoS ONE. 8(9). e75869–e75869. 7 indexed citations
13.
O’Reilly, Linda P., Cliff J. Luke, David H. Perlmutter, Gary A. Silverman, & Stephen C. Pak. (2013). C. elegans in high-throughput drug discovery. Advanced Drug Delivery Reviews. 69-70. 247–253. 192 indexed citations
14.
Miedel, Mark T., et al.. (2011). Using C. elegans to Identify the Protease Targets of Serpins In Vivo. Methods in enzymology on CD-ROM/Methods in enzymology. 499. 283–299. 6 indexed citations
15.
Silverman, Gary A., James C. Whisstock, Stephen Bottomley, et al.. (2010). Serpins Flex Their Muscle. Journal of Biological Chemistry. 285(32). 24299–24305. 126 indexed citations
16.
Askew, David J., Sule Çataltepe, Vasantha Kumar, et al.. (2007). SERPINB11 Is a New Noninhibitory Intracellular Serpin. Journal of Biological Chemistry. 282(34). 24948–24960. 27 indexed citations
17.
Silverman, Gary A., James C. Whisstock, David J. Askew, et al.. (2004). Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cellular and Molecular Life Sciences. 61(3). 301–325. 150 indexed citations
18.
Pak, Stephen C., Vasantha Kumar, Christopher Tsu, et al.. (2004). SRP-2 Is a Cross-class Inhibitor That Participates in Postembryonic Development of the Nematode Caenorhabditis elegans. Journal of Biological Chemistry. 279(15). 15448–15459. 35 indexed citations
19.
Askew, Yuko S., Stephen C. Pak, Cliff J. Luke, et al.. (2001). SERPINB12 Is a Novel Member of the Human ov-serpin Family That Is Widely Expressed and Inhibits Trypsin-like Serine Proteinases. Journal of Biological Chemistry. 276(52). 49320–49330. 43 indexed citations
20.
Uemura, Yoshiki, Stephen C. Pak, Cliff J. Luke, et al.. (2000). Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells. International Journal of Cancer. 89(4). 368–377. 63 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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