David H. Perlmutter

9.1k total citations · 1 hit paper
54 papers, 3.8k citations indexed

About

David H. Perlmutter is a scholar working on Cell Biology, Molecular Biology and Cancer Research. According to data from OpenAlex, David H. Perlmutter has authored 54 papers receiving a total of 3.8k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Cell Biology, 19 papers in Molecular Biology and 14 papers in Cancer Research. Recurrent topics in David H. Perlmutter's work include Endoplasmic Reticulum Stress and Disease (15 papers), Protease and Inhibitor Mechanisms (14 papers) and Autophagy in Disease and Therapy (11 papers). David H. Perlmutter is often cited by papers focused on Endoplasmic Reticulum Stress and Disease (15 papers), Protease and Inhibitor Mechanisms (14 papers) and Autophagy in Disease and Therapy (11 papers). David H. Perlmutter collaborates with scholars based in United States, France and Japan. David H. Perlmutter's co-authors include Lauren K. Willis, Tunda Hidvegi, Michael Ewing, Ross W. Shepherd, Pamela Hale, N.M. Maurice, Christine Dippold, Amitava Mukherjee, Carolyn Kemp and Stephen C. Pak and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

David H. Perlmutter

54 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Functions of autophagy in normal and diseased liver

2013 373 citations Mark J. Czaja, Wen-Xing Ding et al. Autophagy profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David H. Perlmutter United States	30	1.4k	1.2k	1.0k	694	647	54	3.8k
Jeffrey Teckman United States	38	1.7k 1.2×	1.2k 1.0×	1.2k 1.2×	1.4k 2.0×	1.1k 1.7×	113	4.3k
Kasper M.A. Rouschop Netherlands	32	1.9k 1.4×	1.5k 1.3×	862 0.8×	918 1.3×	373 0.6×	67	4.1k
Maria Vittoria Barone Italy	39	2.3k 1.6×	678 0.6×	545 0.5×	392 0.6×	919 1.4×	120	4.8k
Priscilla N. Kelly Australia	19	2.5k 1.8×	662 0.6×	915 0.9×	534 0.8×	1.3k 2.0×	92	4.4k
Deborah Stroka Switzerland	38	2.2k 1.5×	734 0.6×	335 0.3×	1.2k 1.8×	563 0.9×	105	4.7k
Frédéric Luciano France	31	2.8k 2.0×	859 0.7×	492 0.5×	357 0.5×	596 0.9×	56	4.3k
Ewa M. Michalak Australia	27	3.7k 2.6×	798 0.7×	951 0.9×	640 0.9×	1.6k 2.6×	37	5.2k
Mario P. Tschan Switzerland	38	2.2k 1.6×	1.1k 1.0×	320 0.3×	753 1.1×	767 1.2×	116	3.6k
Thomas Grewal Australia	43	3.1k 2.2×	482 0.4×	740 0.7×	1.1k 1.5×	517 0.8×	119	4.8k
Gregory J. Brunn United States	26	2.6k 1.8×	406 0.3×	585 0.6×	296 0.4×	536 0.8×	37	4.3k

Countries citing papers authored by David H. Perlmutter

Since Specialization

Citations

This map shows the geographic impact of David H. Perlmutter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David H. Perlmutter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David H. Perlmutter more than expected).

Fields of papers citing papers by David H. Perlmutter

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David H. Perlmutter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David H. Perlmutter. The network helps show where David H. Perlmutter may publish in the future.

Co-authorship network of co-authors of David H. Perlmutter

This figure shows the co-authorship network connecting the top 25 collaborators of David H. Perlmutter. A scholar is included among the top collaborators of David H. Perlmutter based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David H. Perlmutter. David H. Perlmutter is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Lee, Seong Won, Young Mi Oh, Matheus B. Victor, et al.. (2023). Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1–TFEB pathway to Huntington’s disease neurodegeneration. Nature Aging. 4(1). 95–109. 10 indexed citations

Hidvegi, Tunda, Donna B. Stolz, John F. Alcorn, et al.. (2015). Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy. Journal of Biological Chemistry. 290(50). 29742–29757. 24 indexed citations

Czaja, Mark J., Wen-Xing Ding, Terrence M. Donohue, et al.. (2013). Functions of autophagy in normal and diseased liver. Autophagy. 9(8). 1131–1158. 373 indexed citations breakdown →

Wang, Yan & David H. Perlmutter. (2013). Targeting intracellular degradation pathways for treatment of liver disease caused by α1-antitrypsin deficiency. Pediatric Research. 75(1-2). 133–139. 16 indexed citations

Maurice, N.M. & David H. Perlmutter. (2012). Novel Treatment Strategies for Liver Disease Due to a1‐Antitrypsin Deficiency. Clinical and Translational Science. 5(3). 289–294. 7 indexed citations

Hidvegi, Tunda, Michael Ewing, Pamela Hale, et al.. (2010). An Autophagy-Enhancing Drug Promotes Degradation of Mutant α ₁ -Antitrypsin Z and Reduces Hepatic Fibrosis. Science. 329(5988). 229–232. 463 indexed citations

Gosai, Sager J., Joon Hyeok Kwak, Cliff J. Luke, et al.. (2010). Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z. PLoS ONE. 5(11). e15460–e15460. 135 indexed citations

Kamimoto, Takahiro, Shisako Shoji, Tunda Hidvegi, et al.. (2005). Intracellular Inclusions Containing Mutant α1-Antitrypsin Z Are Propagated in the Absence of Autophagic Activity. Journal of Biological Chemistry. 281(7). 4467–4476. 207 indexed citations

Perlmutter, David H.. (2004). Alpha-1-antitrypsin deficiency: diagnosis and treatment. Clinics in Liver Disease. 8(4). 839–859. 64 indexed citations

10.

Perlmutter, David H.. (2003). α1-Antitrypsin Deficiency: Liver Disease Associated With Retention of a Mutant Secretory Glycoprotein in the Endoplasmic Reticulum. Humana Press eBooks. 232. 39–56. 17 indexed citations

11.

Perlmutter, David H.. (2002). Liver injury in α1-antitrypsin deficiency: an aggregated protein induces mitochondrial injury. Journal of Clinical Investigation. 110(11). 1579–1583. 113 indexed citations

12.

Perlmutter, David H. & Ross W. Shepherd. (2002). Extrahepatic biliary atresia: A disease or a phenotype?. Hepatology. 35(6). 1297–1304. 86 indexed citations

13.

Finegold, Milton J., et al.. (2001). Outcome of Early Hepatic Portoenterostomy for Biliary Atresia. Journal of Pediatric Gastroenterology and Nutrition. 32(3). 265–269. 2 indexed citations

14.

Uemura, Yoshiki, Stephen C. Pak, Cliff J. Luke, et al.. (2000). Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells. International Journal of Cancer. 89(4). 368–377. 63 indexed citations

15.

Perlmutter, David H.. (2000). LIVER INJURY IN ALPHA1-ANTITRYPSIN DEFICIENCY. Clinics in Liver Disease. 4(2). 387–408. 23 indexed citations

16.

Mazziotti, Mark V., Lauren K. Willis, Robert O. Heuckeroth, et al.. (1999). Anomalous development of the hepatobiliary system in the inv mouse. Hepatology. 30(2). 372–378. 94 indexed citations

17.

Goyal, Alka, Jacob C. Langer, Mary M. Zutter, et al.. (1999). Primary Gastric Plasmacytoma: A Rare Cause of Hypertrophic Gastritis in an Adolescent. Journal of Pediatric Gastroenterology and Nutrition. 29(4). 424–430. 8 indexed citations

18.

Haviland, David L., et al.. (1995). N-formylpeptide and complement C5a receptors are expressed in liver cells and mediate hepatic acute phase gene regulation.. The Journal of Experimental Medicine. 182(1). 207–217. 95 indexed citations

19.

Perlmutter, David H.. (1991). The cellular basis for liver injury in α1-antitrypsin deficiency. Hepatology. 13(1). 172–185. 41 indexed citations

20.

Perlmutter, David H., et al.. (1988). Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency.. Journal of Clinical Investigation. 81(6). 1774–1780. 68 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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