Mark T. Miedel

806 citations

26 papers · 541 indexed · h-index 11

Co-authors: Ora A. Weisz Kelly M. Weixel Albert Gough Kirill Kiselyov Lawrence A. Vernetti Richard DeBiasio Ryan M. Reddinger Cliff J. Luke
Topics: Genetics, Aging, and Longevity in Model Organisms (7 papers)Endoplasmic Reticulum Stress and Disease (5 papers)Liver Disease Diagnosis and Treatment (4 papers)
Cited by: Aging Physiology Sensory Systems
Journals: Journal of Biological Chemistry The Journal of Experimental Medicine The Journal of Cell Biology
Partner nations: United States China Poland

In The Last Decade

Mark T. Miedel

26 papers receiving 532 citations

Peers

Countries citing papers authored by Mark T. Miedel

Since Specialization

Citations

This map shows the geographic impact of Mark T. Miedel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark T. Miedel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark T. Miedel more than expected).

Fields of papers citing papers by Mark T. Miedel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark T. Miedel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark T. Miedel. The network helps show where Mark T. Miedel may publish in the future.

Co-authorship network of co-authors of Mark T. Miedel

This figure shows the co-authorship network connecting the top 25 collaborators of Mark T. Miedel. A scholar is included among the top collaborators of Mark T. Miedel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark T. Miedel. Mark T. Miedel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Validation of microphysiological systems for interpreting patient heterogeneity requires robust reproducibility analytics and experimental metadata 2025 ·Cell Reports Methods ·Mark T. Miedel,(unknown),(unknown),(unknown),(unknown),(unknown),Jaideep Behari,Alejandro Soto–Gutiérrez,Albert Gough,D. Lansing Taylor,Mark E. Schurdak	2
2	Integrated Patient Digital and Biomimetic Twins for Precision Medicine: A Perspective 2025 ·Seminars in Liver Disease ·Mark T. Miedel,Mark E. Schurdak,Andrew M. Stern,Alejandro Soto–Gutiérrez,(unknown),Jaideep Behari,D. Lansing Taylor	2
3	Comparison of wild-type and high-risk PNPLA3 variants in a human biomimetic liver microphysiology system for metabolic dysfunction-associated steatotic liver disease precision therapy 2024 ·Frontiers in Cell and Developmental Biology ·(unknown),(unknown),(unknown),(unknown),Richard DeBiasio,(unknown),(unknown),Rodrigo M. Florentino,(unknown),Jacquelyn A. Brown,Lawrence A. Vernetti,Mark E. Schurdak,Andrew M. Stern,Albert Gough,Jaideep Behari,Alejandro Soto–Gutiérrez,D. Lansing Taylor,Mark T. Miedel	7
4	A metabolic dysfunction-associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system 2024 ·Communications Biology ·Julio Aleman,K. Ravikumar,(unknown),Mark E. Schurdak,Lawrence A. Vernetti,(unknown),(unknown),Richard DeBiasio,(unknown),(unknown),Albert Gough,Alejandro Soto–Gutiérrez,Jaideep Behari,Vijay Yechoor,Mark T. Miedel,Andrew M. Stern,Ipsita Banerjee,D. Lansing Taylor	5
5	Evaluation of Human Hepatocyte Drug Metabolism Carrying High-Risk or Protection-Associated Liver Disease Genetic Variants 2023 ·International Journal of Molecular Sciences ·(unknown),(unknown),(unknown),(unknown),(unknown),Zhiping Hu,Takeshi Kurihara,Edgar N. Tafaleng,Rodrigo M. Florentino,Zi Wang,Mengying Xia,Mark T. Miedel,D. Lansing Taylor,Jaideep Behari,Alina Ostrowska,Robert Constantine,Albert P. Li,Alejandro Soto–Gutiérrez	8
6	The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury 2023 ·International Journal of Molecular Sciences ·James J. Beaudoin,(unknown),Mark T. Miedel,Albert Gough,(unknown),(unknown),Kari E. Wong,Rangaprasad Sarangarajan,(unknown),Lisl K.M. Shoda,Scott Q. Siler,D. Lansing Taylor,Brett A. Howell,Lawrence A. Vernetti,Kyunghee Yang	6
7	A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate® 2021 ·Toxicology ·Kristin M. Bircsak,Richard DeBiasio,Mark T. Miedel,(unknown),Ryan M. Reddinger,Anthony D. Saleh,Tongying Shun,Lawrence A. Vernetti,Albert Gough	140
8	Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors 2021 ·Experimental Biology and Medicine ·Manush Saydmohammed,Anupma Jha,Vineet Mahajan,(unknown),Tong Ying Shun,Richard DeBiasio,(unknown),Xiang Li,(unknown),Erin E. Kershaw,Vijay Yechoor,Jaideep Behari,Alejandro Soto–Gutiérrez,Lawrence A. Vernetti,Andrew M. Stern,Albert Gough,Mark T. Miedel,D. Lansing Taylor	10
9	Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System 2019 ·Scientific Reports ·Mark T. Miedel,(unknown),(unknown),Albert Gough,D. Lansing Taylor,Andrew M. Stern	17
10	Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes 2018 ·Oncology ·(unknown),Mark T. Miedel,(unknown),(unknown),Ning Chen,Peilu Wang,Amir Bahreini,Zheqi Li,Zhijie Ding,Tong Ying Shun,Daniel M. Zuckerman,D. Lansing Taylor,Shannon L. Puhalla,Adrian V. Lee,Steffi Oesterreich,Andrew M. Stern	14
11	Activation of the Caenorhabditis elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit 2016 ·Journal of Biological Chemistry ·Shujie Shi,Cliff J. Luke,Mark T. Miedel,Gary A. Silverman,Thomas R. Kleyman	15
12	The Aggregation-Prone Intracellular Serpin SRP-2 Fails to Transit the ER inCaenorhabditis elegans 2015 ·Genetics ·(unknown),Erin E. Cummings,Linda P. O’Reilly,Mark T. Miedel,Gary A. Silverman,Cliff J. Luke,David H. Perlmutter,Stephen C. Pak	1
13	Deficient and Null Variants of SERPINA1 Are Proteotoxic in a Caenorhabditis elegans Model of α1-Antitrypsin Deficiency 2015 ·PLoS ONE ·Erin E. Cummings,Linda P. O’Reilly,Dale E. King,(unknown),Mark T. Miedel,Cliff J. Luke,David H. Perlmutter,Gary A. Silverman,Stephen C. Pak	8
14	Isolation of serpin-interacting proteins in C. elegans using protein affinity purification 2014 ·Methods ·Mark T. Miedel,Xuemei Zeng,Nathan A. Yates,Gary A. Silverman,Cliff J. Luke	3
15	A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover 2014 ·Human Molecular Genetics ·Olivia S. Long,(unknown),Joon Hyeok Kwak,Cliff J. Luke,Sager J. Gosai,Linda P. O’Reilly,Yán Wāng,Jie Li,(unknown),Mark T. Miedel,Donna B. Stolz,Simon C. Watkins,Stephan Züchner,David H. Perlmutter,Gary A. Silverman,Stephen C. Pak	24
16	Loss of Lysosomal Ion Channel Transient Receptor Potential Channel Mucolipin-1 (TRPML1) Leads to Cathepsin B-dependent Apoptosis 2012 ·Journal of Biological Chemistry ·(unknown),Mark T. Miedel,James L. Quinn,(unknown),Ora A. Weisz,Kirill Kiselyov	44
17	A Pro-Cathepsin L Mutant Is a Luminal Substrate for Endoplasmic-Reticulum-Associated Degradation in C. elegans 2012 ·PLoS ONE ·Mark T. Miedel,(unknown),(unknown),Olivia S. Long,Stephen C. Pak,David H. Perlmutter,Gary A. Silverman,Cliff J. Luke	36
18	Using C. elegans to Identify the Protease Targets of Serpins In Vivo 2011 ·Methods in enzymology on CD-ROM/Methods in enzymology ·(unknown),Mark T. Miedel,(unknown),(unknown),Brian L. Hood,Thomas P. Conrads,Gary A. Silverman,Cliff J. Luke	6
19	Posttranslational Cleavage and Adaptor Protein Complex-dependent Trafficking of Mucolipin-1 2006 ·Journal of Biological Chemistry ·Mark T. Miedel,Kelly M. Weixel,Jennifer R. Bruns,Linton M. Traub,Ora A. Weisz	54
20	ADP-ribosylation Factor 1-independent Protein Sorting and Export from the trans-Golgi Network 2004 ·Journal of Biological Chemistry ·Mark Ellis,Mark T. Miedel,Christopher J. Guerriero,Ora A. Weisz	7

About Mark T. Miedel

Mark T. Miedel is a scholar working on Aging, Physiology and Cell Biology, having authored 26 papers that have together received 541 indexed citations. Recurring topics across this work include Genetics, Aging, and Longevity in Model Organisms (7 papers), Endoplasmic Reticulum Stress and Disease (5 papers) and Liver Disease Diagnosis and Treatment (4 papers). The work is most often cited by research in Aging (64 citations), Physiology (138 citations) and Sensory Systems (93 citations). Mark T. Miedel has collaborated with scholars based in United States, China and Poland. Frequent co-authors include Ora A. Weisz, Kelly M. Weixel, Albert Gough, Kirill Kiselyov, Lawrence A. Vernetti, Richard DeBiasio, Ryan M. Reddinger, Cliff J. Luke, Gary A. Silverman and Tongying Shun. Their work appears in journals such as Journal of Biological Chemistry, The Journal of Experimental Medicine and The Journal of Cell Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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