Jason W. Upton

8.2k total citations · 4 hit papers
38 papers, 5.7k citations indexed

About

Jason W. Upton is a scholar working on Immunology, Molecular Biology and Epidemiology. According to data from OpenAlex, Jason W. Upton has authored 38 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Immunology, 21 papers in Molecular Biology and 16 papers in Epidemiology. Recurrent topics in Jason W. Upton's work include interferon and immune responses (16 papers), Cytomegalovirus and herpesvirus research (14 papers) and Cell death mechanisms and regulation (13 papers). Jason W. Upton is often cited by papers focused on interferon and immune responses (16 papers), Cytomegalovirus and herpesvirus research (14 papers) and Cell death mechanisms and regulation (13 papers). Jason W. Upton collaborates with scholars based in United States, United Kingdom and Denmark. Jason W. Upton's co-authors include William J. Kaiser, Edward S. Mocarski, Haripriya Sridharan, Devon Livingston‐Rosanoff, Lisa P. Daley‐Bauer, Alyssa B. Long, Tamara Caspary, Razqallah Hakem, Katherine B. Ragan and Robert W. Marquis and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Jason W. Upton

38 papers receiving 5.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

2011 836 citations William J. Kaiser, Jason W. Upton et al. Nature profile →
Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

2013 747 citations William J. Kaiser, Haripriya Sridharan et al. Journal of Biological Chemistry profile →
DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA

2012 606 citations Jason W. Upton, William J. Kaiser et al. Cell Host & Microbe profile →
Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

2020 370 citations Ting Zhang, Chaoran Yin et al. Cell profile →

Peers

Jason W. Upton

IMMUN

EPIDE

ONCOL

Pingwei Li United States

Patricia Fitzgerald‐Bocarsly United States

Stanley F. Wolf United States

Julián Pardo Spain

Hui Zheng China

Lei Jin China

Ivan K. H. Poon Australia

G. Eric Blair United Kingdom

Ulrike Schleicher Germany

Jie Wang China

Pingwei Li United States

Jason W. Upton

3.7k ×1.0

4.2k ×1.4

IMMUN

940 ×0.7

EPIDE

1.2k ×2.0

ONCOL

1.3k ×2.5

Citations per year, relative to Jason W. Upton Jason W. Upton (= 1×) peers Pingwei Li

Countries citing papers authored by Jason W. Upton

Since Specialization

Citations

This map shows the geographic impact of Jason W. Upton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jason W. Upton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jason W. Upton more than expected).

Fields of papers citing papers by Jason W. Upton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jason W. Upton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jason W. Upton. The network helps show where Jason W. Upton may publish in the future.

Co-authorship network of co-authors of Jason W. Upton

This figure shows the co-authorship network connecting the top 25 collaborators of Jason W. Upton. A scholar is included among the top collaborators of Jason W. Upton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jason W. Upton. Jason W. Upton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Yadav, Santosh K., et al.. (2023). Differential effects of CMV infection on the viability of cardiac cells. Cell Death Discovery. 9(1). 111–111. 4 indexed citations

Koehler, Heather, Ting Zhang, Siddharth Balachandran, et al.. (2021). Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis. Cell Host & Microbe. 29(8). 1266–1276.e5. 103 indexed citations

Lane, Rebecca, Hongyan Guo, Amanda Fisher, et al.. (2020). Necroptosis-based CRISPR knockout screen reveals Neuropilin-1 as a critical host factor for early stages of murine cytomegalovirus infection. Proceedings of the National Academy of Sciences. 117(33). 20109–20116. 25 indexed citations

Zhang, Ting, Chaoran Yin, David F. Boyd, et al.. (2020). Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis. Cell. 180(6). 1115–1129.e13. 370 indexed citations breakdown →

Knowlton, Jonathan J., et al.. (2018). Murine cytomegalovirus M72 promotes acute virus replication in vivo and is a substrate of the TRiC/CCT complex. Virology. 522. 92–105. 8 indexed citations

Guo, Hongyan, Ryan P. Gilley, Amanda Fisher, et al.. (2018). Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1. Cell Death and Disease. 9(8). 816–816. 98 indexed citations

Maelfait, Jonathan, Layal Liverpool, Anne Bridgeman, et al.. (2017). Sensing of viral and endogenous RNA by ZBP 1/ DAI induces necroptosis. The EMBO Journal. 36(17). 2529–2543. 187 indexed citations

Upton, Jason W. & William J. Kaiser. (2017). DAI Another Way: Necroptotic Control of Viral Infection. Cell Host & Microbe. 21(3). 290–293. 19 indexed citations

Sridharan, Haripriya, Katherine B. Ragan, Hongyan Guo, et al.. (2017). Murine cytomegalovirus IE 3‐dependent transcription is required for DAI / ZBP 1‐mediated necroptosis. EMBO Reports. 18(8). 1429–1441. 75 indexed citations

10.

Thapa, Roshan J., Justin P. Ingram, Katherine B. Ragan, et al.. (2016). DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death. Cell Host & Microbe. 20(5). 674–681. 323 indexed citations

11.

Sun, Chenglong, Stefan Schattgen, Prapaporn Pisitkun, et al.. (2015). Evasion of Innate Cytosolic DNA Sensing by a Gammaherpesvirus Facilitates Establishment of Latent Infection. The Journal of Immunology. 194(4). 1819–1831. 80 indexed citations

12.

Upton, Jason W. & Francis Ka-Ming Chan. (2014). Staying Alive: Cell Death in Antiviral Immunity. Molecular Cell. 54(2). 273–280. 129 indexed citations

13.

Sridharan, Haripriya & Jason W. Upton. (2014). Programmed necrosis in microbial pathogenesis. Trends in Microbiology. 22(4). 199–207. 79 indexed citations

14.

Kaiser, William J., Jason W. Upton, & Edward S. Mocarski. (2013). Viral modulation of programmed necrosis. Current Opinion in Virology. 3(3). 296–306. 118 indexed citations

15.

Mocarski, Edward S., Jason W. Upton, & William J. Kaiser. (2011). Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways. Nature reviews. Immunology. 12(2). 79–88. 248 indexed citations

16.

Kaiser, William J., Jason W. Upton, Alyssa B. Long, et al.. (2011). RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature. 471(7338). 368–372. 836 indexed citations breakdown →

17.

Upton, Jason W., William J. Kaiser, & Edward S. Mocarski. (2010). Virus Inhibition of RIP3-Dependent Necrosis. Cell Host & Microbe. 7(4). 302–313. 457 indexed citations

18.

Hendrickson, Jeanne E., Natia Saakadze, Chantel M. Cadwell, et al.. (2009). The spleen plays a central role in primary humoral alloimmunization to transfused mHEL red blood cells. Transfusion. 49(8). 1678–1684. 30 indexed citations

19.

Upton, Jason W., William J. Kaiser, & Edward S. Mocarski. (2008). Cytomegalovirus M45 Cell Death Suppression Requires Receptor-interacting Protein (RIP) Homotypic Interaction Motif (RHIM)-dependent Interaction with RIP1. Journal of Biological Chemistry. 283(25). 16966–16970. 158 indexed citations

20.

Upton, Jason W., Linda F. van Dyk, & Samuel H. Speck. (2005). Characterization of murine gammaherpesvirus 68 v-cyclin interactions with cellular cdks. Virology. 341(2). 271–283. 29 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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