Clair Crewe

3.0k citations

28 papers · 1.7k indexed · 2 hit papers · h-index 17

Impact in

Physiology top 5%
- Adipose Tissue and Metabolism
Cancer Research top 5%
- MicroRNA in disease regulation

Papers in ⓘ

Molecular Biology 21
- Extracellular vesicles in disease 10
- Mitochondrial Function and Pathology 5
Physiology 12
- Adipose Tissue and Metabolism 11

Co-authors: Philipp E. Scherer (16 shared papers)Yu An (4 shared papers)Ruth Gordillo (10 shared papers)Nolwenn Joffin (7 shared papers)Fang Zhang (2 shared papers)Joseph M. Rutkowski (2 shared papers)Dwight A. Towler (1 shared paper)Min Kim (1 shared paper)
Journals: Nature Metabolism (3 papers)Cell Metabolism (2 papers)Diabetes (2 papers)JCI Insight (2 papers)Comprehensive physiology (2 papers)
Partner nations: United States Sweden China

In The Last Decade

Clair Crewe

28 papers receiving 1.7k citations

Hit Papers

align trajectories log scale

Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes 2021 · 277 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Cell Metabolism
2017 Journal of Clinical Investigation

Peers

Countries citing papers authored by Clair Crewe

Since Specialization

Citations

This map shows the geographic impact of Clair Crewe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Clair Crewe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Clair Crewe more than expected).

Fields of papers citing papers by Clair Crewe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Clair Crewe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Clair Crewe. The network helps show where Clair Crewe may publish in the future.

Co-authors

The 25 scholars most cited alongside Clair Crewe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Clair Crewe Line = papers co-authored together Clair Crewe links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 28 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis Journal of Clinical Investigation ·Clair Crewe, Yu An, Philipp E. Scherer Hit paper breakdown →	2017	515
2	An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State Cell ·Clair Crewe, Nolwenn Joffin, Joseph M. Rutkowski, Min Kim, Fang Zhang, Dwight A. Towler, Ruth Gordillo, Philipp E. Scherer	2018	309
3	Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes Cell Metabolism ·Clair Crewe, Jan‐Bernd Funcke, Shujuan Li, Nolwenn Joffin, Christy Gliniak, Alexandra L. Ghaben, Yu An, Hesham A. Sadek, Ruth Gordillo, Yucel Akgul, Shiuhwei Chen, Dmitri Samovski, Pamela Fischer‐Posovszky, Christine M. Kusminski, Samuel Klein, Philipp E. Scherer Hit paper breakdown →	2021	277
4	Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations Nature Metabolism ·Nolwenn Joffin, Christy Gliniak, Jan‐Bernd Funcke, Vivian A. Paschoal, Clair Crewe, Shiuhwei Chen, Ruth Gordillo, Christine M. Kusminski, Da Young Oh, Werner J. Geldenhuys, Philipp E. Scherer	2022	58
5	Human endotrophin as a driver of malignant tumor growth JCI Insight ·Dawei Bu, Clair Crewe, Christine M. Kusminski, Ruth Gordillo, Alexandra L. Ghaben, Min Gyu Kim, Jiyoung Park, Hui Deng, Wei Xiong, Xiao‐Zheng Liu, Per Eystein Lønning, Nils Halberg, Adan Rios, Yujun Chang, Anneliese Gonzalez, Ningyan Zhang, Zhiqiang An, Philipp E. Scherer	2019	54
6	SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1 JCI Insight ·Clair Crewe, Yi Zhu, Vivian A. Paschoal, Nolwenn Joffin, Alexandra L. Ghaben, Ruth Gordillo, Da Young Oh, Guosheng Liang, Jay D. Horton, Philipp E. Scherer	2019	51
7	Regulation of Pyruvate Dehydrogenase Kinase 4 in the Heart through Degradation by the Lon Protease in Response to Mitochondrial Substrate Availability Journal of Biological Chemistry ·Clair Crewe, Christopher M. Schafer, Irene Lee, Michael Kinter, Luke I. Szweda	2016	50
8	Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue Cell stem cell ·Nolwenn Joffin, Vivian A. Paschoal, Christy Gliniak, Clair Crewe, Abdallah Elnwasany, Luke I. Szweda, Qianbin Zhang, Chelsea Hepler, Christine M. Kusminski, Ruth Gordillo, Da Young Oh, Rana K. Gupta, Philipp E. Scherer	2021	47
9	Dysregulation of amyloid precursor protein impairs adipose tissue mitochondrial function and promotes obesity Nature Metabolism ·Yu An, Clair Crewe, Ingrid Wernstedt Asterholm, Kai Sun, Shiuhwei Chen, Fang Zhang, Mengle Shao, Jan‐Bernd Funcke, Zhuzhen Zhang, Leon G. Straub, Jun Yoshino, Samuel Klein, Christine M. Kusminski, Philipp E. Scherer	2019	43
10	Intercellular and interorgan crosstalk through adipocyte extracellular vesicles Reviews in Endocrine and Metabolic Disorders ·Clair Crewe, Philipp E. Scherer	2021	43
11	Rapid Inhibition of Pyruvate Dehydrogenase: An Initiating Event in High Dietary Fat-Induced Loss of Metabolic Flexibility in the Heart PLoS ONE ·Clair Crewe, Michael Kinter, Luke I. Szweda	2013	42
12	Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria American Journal of Physiology-Heart and Circulatory Physiology ·Paul M. Rindler, Clair Crewe, Jolyn Fernandes, Michael Kinter, Luke I. Szweda	2013	41
13	A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia Diabetes ·Christine M. Kusminski, Alexandra L. Ghaben, Thomas S. Morley, Ricardo J. Samms, Andrew C. Adams, Yu An, Joshua A. Johnson, Nolwenn Joffin, Toshiharu Onodera, Clair Crewe, William L. Holland, Ruth Gordillo, Philipp E. Scherer	2019	39
14	Hyaluronan in adipose tissue: Beyond dermal filler and therapeutic carrier Science Translational Medicine ·Yi Zhu, Clair Crewe, Philipp E. Scherer	2016	30
15	Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus PLoS Pathogens ·Rong Yang, Eunice E. Lee, Jiwoong Kim, Joon H. Choi, Elysha Kolitz, Yating Chen, Clair Crewe, Nicholas J. H. Salisbury, Philipp E. Scherer, Clay J. Cockerell, Taylor R. Smith, (unknown), Louisa Verlinden, Denise A. Galloway, Christopher B. Buck, Mariet C.W. Feltkamp, Christopher S. Sullivan, Richard C. Wang	2021	28
16	Endogenous self-peptides guard immune privilege of the central nervous system Nature ·Min Woo Kim, Wenqing Gao, Cheryl F. Lichti, Xingxing Gu, Taitea Dykstra, Jay Cao, Igor Smirnov, Pavle Boskovic, Denis Kleverov, Andrea Francesca Salvador, Antoine Drieu, Kyungdeok Kim, Susan Blackburn, Clair Crewe, Maxim N. Artyomov, Emil R. Unanue, Jonathan Kipnis	2024	19
17	A guide to studying mitochondria transfer Nature Cell Biology ·Snigdha Tiash, Jonathan R. Brestoff, Clair Crewe	2023	18
18	Energetic Stress‐Induced Metabolic Regulation by Extracellular Vesicles Comprehensive physiology ·Clair Crewe	2023	13
19	Deficient Caveolin-1 Synthesis in Adipocytes Stimulates Systemic Insulin-Independent Glucose Uptake via Extracellular Vesicles Diabetes ·Clair Crewe, Shiuhwei Chen, Dawei Bu, Christy Gliniak, Ingrid Wernstedt Asterholm, Xin Xin Yu, Nolwenn Joffin, Camila Oliveira de Souza, Jan‐Bernd Funcke, Da Young Oh, Oleg Varlamov, Jacob J. Robino, Ruth Gordillo, Philipp E. Scherer	2022	12
20	Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnlβ (RELMβ) Null Mice American Journal Of Pathology ·Ingrid Wernstedt Asterholm, Ja Young Kim-Muller, Joseph M. Rutkowski, Clair Crewe, Caroline Tao, Philipp E. Scherer	2016	10

About Clair Crewe

Clair Crewe is a scholar working on Molecular Biology, Physiology, Epidemiology, Cancer Research and Cardiology and Cardiovascular Medicine, having authored 28 papers that have together received 1.7k indexed citations. Recurring topics across this work include Adipose Tissue and Metabolism (11 papers), Extracellular vesicles in disease (10 papers), MicroRNA in disease regulation (6 papers), Adipokines, Inflammation, and Metabolic Diseases (6 papers), Mitochondrial Function and Pathology (5 papers), Cardiovascular Disease and Adiposity (4 papers), Autophagy in Disease and Therapy (3 papers) and Pancreatic function and diabetes (2 papers). The work is most often cited by research in Physiology (688 citations), Cancer Research (351 citations), Cardiology and Cardiovascular Medicine (391 citations), Epidemiology (582 citations) and Molecular Biology (865 citations). Clair Crewe has collaborated with scholars based in United States, Sweden and China. Frequent co-authors include Philipp E. Scherer, Yu An, Ruth Gordillo, Nolwenn Joffin, Fang Zhang, Joseph M. Rutkowski, Dwight A. Towler, Min Kim, Luke I. Szweda and Christine M. Kusminski. Their work appears in journals such as Nature Metabolism, Cell Metabolism, Diabetes, JCI Insight and Comprehensive physiology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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