D. D. Breimer

11.6k total citations · 1 hit paper
267 papers, 9.4k citations indexed

About

D. D. Breimer is a scholar working on Molecular Biology, Oncology and Pediatrics, Perinatology and Child Health. According to data from OpenAlex, D. D. Breimer has authored 267 papers receiving a total of 9.4k indexed citations (citations by other indexed papers that have themselves been cited), including 62 papers in Molecular Biology, 58 papers in Oncology and 51 papers in Pediatrics, Perinatology and Child Health. Recurrent topics in D. D. Breimer's work include Drug Transport and Resistance Mechanisms (57 papers), Pharmacological Effects and Toxicity Studies (36 papers) and Pharmacogenetics and Drug Metabolism (33 papers). D. D. Breimer is often cited by papers focused on Drug Transport and Resistance Mechanisms (57 papers), Pharmacological Effects and Toxicity Studies (36 papers) and Pharmacogenetics and Drug Metabolism (33 papers). D. D. Breimer collaborates with scholars based in Netherlands, United Kingdom and China. D. D. Breimer's co-authors include Albertus G. de Boer, Meindert Danhof, Elizabeth C. M. de Lange, Johan Kuiper, Helga E. de Vries, Margret C.M. Blom-Roosemalen, Adam F. Cohen, A.G. de Boer, P. van Brummelen and A.J. Baars and has published in prestigious journals such as Nature, Science and Journal of Clinical Investigation.

In The Last Decade

D. D. Breimer

263 papers receiving 8.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The influence of cytokines on the integrity of the blood-brain barrier in vitro

1996 553 citations Helga E. de Vries, Margret C.M. Blom-Roosemalen et al. Journal of Neuroimmunology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
D. D. Breimer Netherlands	53	2.2k	2.1k	1.7k	1.7k	1.0k	267	9.4k
Yasufumi Sawada Japan	46	1.8k 0.8×	2.9k 1.4×	1.7k 1.0×	2.1k 1.3×	965 0.9×	362	7.7k
Jürgen Drewe Switzerland	65	3.0k 1.4×	2.6k 1.2×	1.5k 0.9×	989 0.6×	1.1k 1.1×	306	15.3k
Andrew A. Somogyi Australia	50	1.3k 0.6×	1.2k 0.6×	1.7k 1.0×	2.1k 1.3×	2.1k 2.0×	253	9.1k
Akira Tsuji Japan	50	2.7k 1.2×	5.3k 2.5×	2.5k 1.4×	1.1k 0.6×	1.3k 1.2×	182	9.5k
Gary M. Pollack United States	42	958 0.4×	2.3k 1.1×	1.7k 1.0×	818 0.5×	469 0.5×	138	5.3k
Elizabeth C. M. de Lange Netherlands	42	1.6k 0.7×	2.1k 1.0×	1.5k 0.9×	419 0.3×	743 0.7×	155	6.2k
Gérard Siest France	61	4.1k 1.8×	1.7k 0.8×	1.2k 0.7×	2.5k 1.5×	808 0.8×	519	14.5k
R.C. Heel United States	67	2.1k 0.9×	808 0.4×	688 0.4×	732 0.4×	1.7k 1.6×	111	10.9k
Kay Brune Germany	65	3.0k 1.3×	955 0.5×	965 0.6×	1.9k 1.1×	5.2k 5.0×	345	14.5k
Heyo K. Kroemer Germany	57	2.4k 1.1×	4.2k 2.0×	2.1k 1.2×	1.5k 0.9×	619 0.6×	180	9.8k

Countries citing papers authored by D. D. Breimer

Since Specialization

Citations

This map shows the geographic impact of D. D. Breimer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by D. D. Breimer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites D. D. Breimer more than expected).

Fields of papers citing papers by D. D. Breimer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by D. D. Breimer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by D. D. Breimer. The network helps show where D. D. Breimer may publish in the future.

Co-authorship network of co-authors of D. D. Breimer

This figure shows the co-authorship network connecting the top 25 collaborators of D. D. Breimer. A scholar is included among the top collaborators of D. D. Breimer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with D. D. Breimer. D. D. Breimer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sandt, Inez C. J. van der, et al.. (2001). Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood–brain barrier. AIDS. 15(4). 483–491. 97 indexed citations

Sandt, Inez C. J. van der, Margret C.M. Blom-Roosemalen, Albertus G. de Boer, & D. D. Breimer. (2000). Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1:MDR1 and Caco-2 cell lines. European Journal of Pharmaceutical Sciences. 11(3). 207–214. 101 indexed citations

Tanaka, Einosuke & D. D. Breimer. (1997). In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease. Journal of Clinical Pharmacy and Therapeutics. 22(4). 237–249. 36 indexed citations

Tuk, Bert, Janine Oberyé, Monique S. M. Pieters, et al.. (1997). Pharmacodynamics of temazepam in primary insomnia: Assessment of the value of quantitative electroencephalography and saccadic eye movements in predicting improvement of sleep. Clinical Pharmacology & Therapeutics. 62(4). 444–452. 12 indexed citations

Breimer, D. D. & Meindert Danhof. (1997). Relevance of the Application of Pharmacokinetic-Pharmacodynamic Modelling Concepts in Drug Development. Clinical Pharmacokinetics. 32(4). 259–267. 79 indexed citations

Vries, Helga E. de, Margret C.M. Blom-Roosemalen, Marijke van Oosten, et al.. (1996). The influence of cytokines on the integrity of the blood-brain barrier in vitro. Journal of Neuroimmunology. 64(1). 37–43. 553 indexed citations breakdown →

Lange, Elizabeth C. M. de, M.B. Hesselink, Meindert Danhof, Albertus G. de Boer, & D. D. Breimer. (1995). The Use of Intracerebral Microdialysis to Determine Changes in Blood-Brain Barrier Transport Characteristics. Pharmaceutical Research. 12(1). 129–133. 25 indexed citations

Lange, Elizabeth C. M. de, et al.. (1995). The Use of Intracerebral Microdialysis for the Determination of Pharmacokinetic Profiles of Anticancer Drugs in Tumor-Bearing Rat Brain. Pharmaceutical Research. 12(12). 1924–1931. 33 indexed citations

Mathôt, Ron A. A., E.A. van Schaick, M.W.E. Langemeijer, et al.. (1994). Pharmacokinetic-pharmacodynamic relationship of the cardiovascular effects of adenosine A1 receptor agonist N6-cyclopentyladenosine in the rat.. Journal of Pharmacology and Experimental Therapeutics. 268(2). 616–624. 45 indexed citations

10.

Boer, Anthonius de, et al.. (1991). Influence of Chlorthalidone on the Pharmacokinetics and Pharmacodynamics of Org 10172 (Lomoparan®), A Low Molecular Weight Heparinoid, in Healthy Volunteers. The Journal of Clinical Pharmacology. 31(7). 611–617. 5 indexed citations

11.

Boer, Angela G. E. M. de, et al.. (1991). Interaction Study between Org 10172, a Low Molecular Weight Heparinoid, and Acetylsalicylic Acid in Healthy Male Volunteers. Thrombosis and Haemostasis. 66(2). 202–207. 7 indexed citations

12.

Boer, Angela G. E. M. de, et al.. (1991). Studies of interaction of a low-molecular-weight heparinoid (Org 10172) with cloxacillin and ticarcillin in healthy male volunteers. Antimicrobial Agents and Chemotherapy. 35(10). 2110–2115. 3 indexed citations

13.

Soons, P.A., et al.. (1990). Pharmacokinetics and metabolism of nifedipine and its metabolites in rats : in-vivo oxidative cleavage of a pyridine-carboxylic acid ester metabolite of nifedipine. Journal of Pharmacobio-Dynamics. 13(4). 3 indexed citations

14.

Boer, Albertus G. de, et al.. (1990). Transport of Desglycinamide-Arginine Vasopressin Across the Blood–Brain Barrier in Rats as Evaluated by the Unit Impulse Response Methodology. Pharmaceutical Research. 7(3). 293–298. 13 indexed citations

15.

Hoogdalem, Ewoud J. van, et al.. (1988). Absorption Enhancement of Rectally Infused Cefoxitin Sodium by Medium-Chain Fatty Acids in Conscious Rats: Concentration–Effect Relationship. Pharmaceutical Research. 5(7). 453–456. 24 indexed citations

16.

Richter, E., et al.. (1982). GLUCURONIDE CONJUGATION AS AN ALTERNATIVE BIOTRANSFORMATION PATHWAY OF HEXOBARBITAL AND METHOHEXITAL IN RATS WITH EXPERIMENTAL HEPATITIS AND CHOLESTASIS. Gastroentérologie Clinique et Biologique. 6(10). 825–825. 1 indexed citations

17.

Mukhtar, Hasan, et al.. (1981). Glutathione S-Transferase Activity in Human Fetal and Adult Tissues. Pharmacology. 22(5). 322–329. 29 indexed citations

18.

Bladeren, Peter J. van, et al.. (1981). The metabolic formation of N-acetyl-S-2-hydroxyethyl-L-cysteine from tetradeutero-1, 2-dibromoethane. Relative importance of oxidation and glutathione conjugation in vivo. Biochemical Pharmacology. 30(17). 2499–2502. 58 indexed citations

19.

Breimer, D. D.. (1980). Towards better safety of drugs and pharmaceutical products : proceedings of the 39th International Congress of Pharmaceutical Sciences of F.I.P., held in Brighton, U.K., September 3-7, 1979. Elsevier eBooks. 1 indexed citations

20.

Baars, A.J., J.A. Zijlstra, E. Vogel, & D. D. Breimer. (1977). The occurrence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity in drosophila melanogaster microsomes, and the importance of this metabolizing capacity for the screening of carcinogenic and mutagenic properties of foreign compounds. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 44(2). 257–267. 57 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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