D. D. Breimer

11.6k citations

267 papers · 9.4k indexed · 1 hit paper · h-index 53

Impact in

Pharmacology top 0.05%
- Pharmacogenetics and Drug Metabolism
- Antibiotics Pharmacokinetics and Efficacy
Pharmaceutical Science top 0.2%
- Advanced Drug Delivery Systems

Papers in ⓘ

Molecular Biology 62
Oncology 58
- Drug Transport and Resistance Mechanisms 57

Co-authors: Albertus G. de Boer (65 shared papers)Meindert Danhof (40 shared papers)Elizabeth C. M. de Lange (14 shared papers)Johan Kuiper (9 shared papers)Helga E. de Vries (7 shared papers)Margret C.M. Blom-Roosemalen (9 shared papers)Adam F. Cohen (18 shared papers)A.G. de Boer (17 shared papers)
Journals: Clinical Pharmacology & Therapeutics (22 papers)Pharmaceutical Research (16 papers)Journal of Pharmacology and Experimental Therapeutics (16 papers)Biochemical Pharmacology (16 papers)European Journal of Clinical Pharmacology (13 papers)
Partner nations: Netherlands United Kingdom China

In The Last Decade

D. D. Breimer

263 papers receiving 8.9k citations

Hit Papers

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The influence of cytokines on the integrity of the blood-brain barrier in vitro 1996 · 553 citations

Peers

Countries citing papers authored by D. D. Breimer

Since Specialization

Citations

This map shows the geographic impact of D. D. Breimer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by D. D. Breimer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites D. D. Breimer more than expected).

Fields of papers citing papers by D. D. Breimer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by D. D. Breimer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by D. D. Breimer. The network helps show where D. D. Breimer may publish in the future.

Co-authors

The 25 scholars most cited alongside D. D. Breimer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with D. D. Breimer Line = papers co-authored together D. D. Breimer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 267 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The influence of cytokines on the integrity of the blood-brain barrier in vitro Journal of Neuroimmunology ·Helga E. de Vries, Margret C.M. Blom-Roosemalen, Marijke van Oosten, Albert G. de Boer, Theo J.C. van Berkel, D. D. Breimer, Johan Kuiper Hit paper breakdown →	1996	553
2	The Blood-Brain Barrier in Neuroinflammatory Diseases Pharmacological Reviews ·Helga E. de Vries, Johan Kuiper, Albertus G. de Boer, Theo J.C. van Berkel, D. D. Breimer	1997	348
3	Penetration of Dexamethasone into Brain Glucocorticoid Targets Is Enhanced in mdr1A P-Glycoprotein Knockout Mice* Endocrinology ·Onno C. Meijer, Elizabeth C. M. de Lange, D. D. Breimer, Albertus G. de Boer, Judith O Workel, E. R. de Kloet	1998	301
4	Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier Journal of Clinical Investigation ·Jan Wijnholds, Elizabeth C. M. de Lange, George L. Scheffer, Dirk‐Jan van den Berg, Carla A.A.M. Mol, Martin van der Valk, Alfred H. Schinkel, Rik J. Scheper, D. D. Breimer, Piet Borst	2000	282
5	Establishment and functional characterization of an in vitro model of the blood–brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes European Journal of Pharmaceutical Sciences ·Pieter J. Gaillard, Levina Helena Voorwinden, Jette Lyngholm Nielsen, Ivanov Aa, Ryo Atsumi, Helena Engman, Carina Ringbom, Albertus G. de Boer, D. D. Breimer	2001	267
6	Lamotrigine, a new anticonvulsant: Pharmacokinetics in normal humans Clinical Pharmacology & Therapeutics ·Adam F. Cohen, G. Land, D. D. Breimer, W. C. Yuen, C Winton, A. W. Peck	1987	241
7	Methodological issues in microdialysis sampling for pharmacokinetic studies Advanced Drug Delivery Reviews ·Elizabeth C. M. de Lange, Albertus G. de Boer, D. D. Breimer	2000	200
8	Rectal Drug Administration Clinical Pharmacokinetics ·Albertus G. de Boer, Frits Moolenaar, Leo G. J. de Leede, D. D. Breimer	1982	190
9	Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite α-hydroxymidazolam in healthy volunteers Clinical Pharmacology & Therapeutics ·Jaap W Mandona, Bert Tuk, Alfred L van Steveninck, D. D. Breimer, Adam F. Cohen, Meindert Danhof	1992	179
10	Variability in nifedipine pharmacokinetics and dynamics: A new oxidation polymorphism in man Biochemical Pharmacology ·C. H. Kleinbloesem, P. van Brummelen, Hette Faber, Meindert Danhof, Nico Vermeulen, D. D. Breimer	1984	156
11	The role of glutathione conjugation in the mutagenicity of 1,2-dibromoethane Biochemical Pharmacology ·Peter J. van Bladeren, D. D. Breimer, G.M.T. Rotteveel-Smijs, R.A.W. De Jong, Wim Buijs, A. VAN DER GEN, G.R. Mohn	1980	138
12	The influence of phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin on glutathione s-transferase activity of rat liver cytosol Biochemical Pharmacology ·A.J. Baars, M. Jansen, D. D. Breimer	1978	133
13	Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs. Journal of Pharmacology and Experimental Therapeutics ·J. B. Bree, A.G. de Boer, Meindert Danhof, L.A. Ginsel, D. D. Breimer	1988	121
14	Studies on the Different Metabolic Pathways of Antipyrine in Rats: Influence of Phenobarbital and 3-Methylcholanthrene Treatment Xenobiotica ·Meindert Danhof, D. P. Krom, D. D. Breimer	1979	116
15	Intestinal drug absorption enhancement: An overview Pharmacology & Therapeutics ·Ewoud J. van Hoogdalem, Albertus G. de Boer, D. D. Breimer	1989	112
16	Interindividual Variations in Drug Disposition Clinical Pharmacokinetics ·D. D. Breimer	1983	108
17	Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1:MDR1 and Caco-2 cell lines European Journal of Pharmaceutical Sciences ·Inez C. J. van der Sandt, Margret C.M. Blom-Roosemalen, Albertus G. de Boer, D. D. Breimer	2000	101
18	A comparison of the sensitivities of adaptive tracking, eye movement analysis, and visual analog lines to the effects of incremental doses of temazepam in healthy volunteers Clinical Pharmacology & Therapeutics ·Alfred L van Steveninck, Rik C. Schoemaker, Monique S. M. Pieters, Ria Kroon, D. D. Breimer, Adam F. Cohen	1991	101
19	Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood–brain barrier AIDS ·Inez C. J. van der Sandt, Catharina M.P. Vos, Lobna Nabulsi, Margret C.M. Blom-Roosemalen, Heleen H. Voorwinden, A.G. de Boer, D. D. Breimer	2001	97
20	Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans Clinical Pharmacology & Therapeutics ·P.A. Soons, Birgit A. P. M. Vogels, M.C.M. Roosemalen, Rik C. Schoemaker, Eiji Uchida, Boo Edgar, Jonas Lundahl, Adam F. Cohen, D. D. Breimer	1991	96

About D. D. Breimer

D. D. Breimer is a scholar working on Molecular Biology, Oncology, Pediatrics, Perinatology and Child Health, Pharmacology and Pharmacology, having authored 267 papers that have together received 9.4k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (57 papers), Pharmacological Effects and Toxicity Studies (36 papers), Pharmacogenetics and Drug Metabolism (33 papers), Epilepsy research and treatment (31 papers), Analytical Methods in Pharmaceuticals (21 papers), Antibiotics Pharmacokinetics and Efficacy (20 papers), Neuroscience and Neuropharmacology Research (19 papers) and Metabolism and Genetic Disorders (19 papers). The work is most often cited by research in Pharmacology (1.7k citations), Pharmaceutical Science (768 citations), Neurology (858 citations), Pediatrics, Perinatology and Child Health (1.7k citations) and Oncology (2.1k citations). D. D. Breimer has collaborated with scholars based in Netherlands, United Kingdom and China. Frequent co-authors include Albertus G. de Boer, Meindert Danhof, Elizabeth C. M. de Lange, Johan Kuiper, Helga E. de Vries, Margret C.M. Blom-Roosemalen, Adam F. Cohen, A.G. de Boer, P. van Brummelen and A.J. Baars. Their work appears in journals such as Clinical Pharmacology & Therapeutics, Pharmaceutical Research, Journal of Pharmacology and Experimental Therapeutics, Biochemical Pharmacology and European Journal of Clinical Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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