Cuifen Hou

729 citations

23 papers · 586 indexed · h-index 13

Impact in

Cellular and Molecular Neuroscience top 10%
- Neuropeptides and Animal Physiology
Molecular Biology
- Receptor Mechanisms and Signaling
- Protein Kinase Regulation and GTPase Signaling
- Ion channel regulation and function
- Chemical Synthesis and Analysis

Papers in ⓘ

Molecular Biology 18
- Chemical Synthesis and Analysis 8
- Receptor Mechanisms and Signaling 4
- Protein Kinase Regulation and GTPase Signaling 3
Oncology 15
- Chemokine receptors and signaling 12
- Drug Transport and Resistance Mechanisms 3

Co-authors: Montserrat Camps (2 shared papers)Peter Gierschik (2 shared papers)Karl H. Jakobs (1 shared paper)Jeffry B. Stock (1 shared paper)Dimitrios N. Sidiropoulos (1 shared paper)Monica Singer (9 shared papers)Druie Cavender (6 shared papers)Dennis Argentieri (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (14 papers)ACS Medicinal Chemistry Letters (2 papers)Journal of Medicinal Chemistry (2 papers)SLAS DISCOVERY (1 paper)Journal of Pharmacology and Experimental Therapeutics (1 paper)
Partner nations: United States Germany

In The Last Decade

Cuifen Hou

23 papers receiving 570 citations

Peers

Countries citing papers authored by Cuifen Hou

Since Specialization

Citations

This map shows the geographic impact of Cuifen Hou's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cuifen Hou with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cuifen Hou more than expected).

Fields of papers citing papers by Cuifen Hou

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cuifen Hou. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cuifen Hou. The network helps show where Cuifen Hou may publish in the future.

Co-authors

The 25 scholars most cited alongside Cuifen Hou, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Cuifen Hou Line = papers co-authored together Cuifen Hou links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 23 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Stimulation of phospholipase C by guanine‐nucleotide‐binding protein βγ subunits European Journal of Biochemistry ·Montserrat Camps, Cuifen Hou, Dimitrios N. Sidiropoulos, Jeffry B. Stock, Karl H. Jakobs, Peter Gierschik	1992	230
2	In Vivo Activity of a Phospholipase C Inhibitor, 1-(6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1 H-pyrrole-2,5-dione (U73122), in Acute and Chronic Inflammatory Reactions Journal of Pharmacology and Experimental Therapeutics ·Cuifen Hou, Thomas Kirchner, Monica Singer, Michele Matheis, Dennis Argentieri, Druie Cavender	2004	56
3	Modeling the G-protein-coupled neuropeptide Y Y1 receptor agonist and antagonist binding sites Protein Engineering Design and Selection ·Ping Du, John Salon, Joseph A. Tamm, Cuifen Hou, Weili Cui, Mary W. Walker, Nika Adham, Dale Dhanoa, Imadul Islam, P J Vaysse, B. Dowling, Yelena Shifman, N. Boyle, H. Rüeger, Tibur Schmidlin, Yuki Yamaguchi, T. A. Branchek, R. L. Weinshank, Charles Gluchowski	1997	48
4	Guanosine 5′-[γ-thio]triphosphate-stimulated hydrolysis of phosphatidylinositol 4,5-bisphosphate in HL-60 granulocytes. Evidence that the guanine nucleotide acts by relieving phospholipase C from an inhibitory constraint Biochemical Journal ·Montserrat Camps, Cuifen Hou, K H Jakobs, Peter Gierschik	1990	34
5	Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma Bioorganic & Medicinal Chemistry Letters ·Bharat Lagu, Chrissy Gerchak, Meng Pan, Cuifen Hou, Monica Singer, Ravi Malaviya, Michele Matheis, Gil Olini, Druie Cavender, Michael P. Wachter	2007	21
6	Synthesis, Structure−Activity Relationship and in Vivo Antiinflammatory Efficacy of Substituted Dipiperidines as CCR2 Antagonists Journal of Medicinal Chemistry ·Mingde Xia, Cuifen Hou, Duane E. DeMong, Scott R. Pollack, Meng Pan, James Brackley, Nareshkumar Jain, Chrissy Gerchak, Monica Singer, Ravi Malaviya, Michele Matheis, Gil Olini, Druie Cavender, Michael P. Wachter	2007	19
7	Overcoming hERG activity in the discovery of a series of 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·Xuqing Zhang, Heather R. Hufnagel, Thomas Markotan, James C. Lanter, Chaozhong Cai, Cuifen Hou, Monica Singer, Evan E. Opas, Sandra McKenney, Carl Crysler, Dana L. Johnson, Zhihua Sui	2011	18
8	A novel series of N-(azetidin-3-yl)-2-(heteroarylamino)acetamide CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·Nalin L. Subasinghe, James C. Lanter, Thomas Markotan, Evan E. Opas, Sandra McKenney, Carl Crysler, Cuifen Hou, John O’Neill, Dana L. Johnson, Zhihua Sui	2012	17
9	Tetrahydroindazole derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists Bioorganic & Medicinal Chemistry Letters ·Jay M. Matthews, James J. McNally, Peter J. Connolly, Mingde Xia, Bin Zhu, Shawn C. Black, Cailin Chen, Cuifen Hou, Yin Liang, Yuting Tang, Mark J. Macielag	2016	15
10	Synthesis and structure–activity relationship of 7-azaindole piperidine derivatives as CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·Mingde Xia, Cuifen Hou, Duane E. DeMong, Scott R. Pollack, Meng Pan, Monica Singer, Michele Matheis, William V. Murray, Druie Cavender, Michael P. Wachter	2008	14
11	Evaluation of anti-diabetic effect and gall bladder function with 2-thio-5-thiomethyl substituted imidazoles as TGR5 receptor agonists Bioorganic & Medicinal Chemistry Letters ·Xuqing Zhang, Zhihua Sui, Jack A. Kauffman, Cuifen Hou, Cailin Chen, Fuyong Du, Thomas Kirchner, Yin Liang, Dana L. Johnson, William V. Murray, Keith T. Demarest	2017	14
12	Discovery of a 4-Azetidinyl-1-thiazoyl-cyclohexane CCR2 Antagonist as a Development Candidate ACS Medicinal Chemistry Letters ·Xuqing Zhang, Cuifen Hou, Heather R. Hufnagel, Monica Singer, Evan E. Opas, Sandra McKenney, Dana L. Johnson, Zhihua Sui	2012	14
13	Substituted dipiperidine alcohols as potent CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·Mingde Xia, Cuifen Hou, Duane E. DeMong, Scott R. Pollack, Meng Pan, James Brackley, Monica Singer, Michele Matheis, Druie Cavender, Michael P. Wachter	2008	12
14	6-Benzhydryl-4-amino-quinolin-2-ones as Potent Cannabinoid Type 1 (CB₁) Receptor Inverse Agonists and Chemical Modifications for Peripheral Selectivity Journal of Medicinal Chemistry ·Zhang Yue-mei, Michael N. Greco, Mark J. Macielag, Christopher A. Teleha, Renée L. DesJarlais, Yuting Tang, George Ho, Cuifen Hou, Cailin Chen, Shuyuan Zhao, Jack A. Kauffman, Raul C. Camacho, Jenson Qi, William V. Murray, Keith T. Demarest, James Leonard	2018	12
15	Monitoring Inositol-Specific Phospholipase C Activity Using a Phospholipid FlashPlate® SLAS DISCOVERY ·Thomas R. Mullinax, Georgette Henrich, Patricia Kasila, David G. Ahern, E A Wenske, Cuifen Hou, Dennis Argentieri, Michael E. Bembenek	1999	9
16	Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes ACS Medicinal Chemistry Letters ·Xuqing Zhang, Mark J. Wall, Zhihua Sui, Jack A. Kauffman, Cuifen Hou, Cailin Chen, Fuyong Du, Thomas Kirchner, Yin Liang, Dana L. Johnson, William V. Murray, Keith T. Demarest	2017	9
17	Design, synthesis and SAR of indazole and benzoisoxazole containing 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·Xuqing Zhang, Heather R. Hufnagel, Cuifen Hou, Evan E. Opas, Sandra McKenney, Carl Crysler, John O’Neill, Dana L. Johnson, Zhihua Sui	2011	8
18	The discovery of novel cyclohexylamide CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·James C. Lanter, Thomas Markotan, Xuqing Zhang, Nalin L. Subasinghe, Fu‐An Kang, Cuifen Hou, Monica Singer, Evan E. Opas, Sandra McKenney, Carl Crysler, Dana L. Johnson, Christopher J. Molloy, Zhihua Sui	2011	8
19	Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·Mingde Xia, Cuifen Hou, Scott R. Pollack, James Brackley, Duane E. DeMong, Meng Pan, Monica Singer, Michele Matheis, Gil Olini, Druie Cavender, Michael P. Wachter	2007	7
20	Novel 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·Chaozhong Cai, Fu‐An Kang, Cuifen Hou, John O’Neill, Evan E. Opas, Sandra McKenney, Dana L. Johnson, Zhihua Sui	2012	6

About Cuifen Hou

Cuifen Hou is a scholar working on Molecular Biology, Oncology, Cellular and Molecular Neuroscience, Pharmacology and Immunology, having authored 23 papers that have together received 586 indexed citations. Recurring topics across this work include Chemokine receptors and signaling (12 papers), Chemical Synthesis and Analysis (8 papers), Neuropeptides and Animal Physiology (5 papers), Receptor Mechanisms and Signaling (4 papers), Cannabis and Cannabinoid Research (3 papers), Protein Kinase Regulation and GTPase Signaling (3 papers), Drug Transport and Resistance Mechanisms (3 papers) and Neuroscience and Neuropharmacology Research (3 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (126 citations), Molecular Biology (400 citations), Cell Biology (80 citations), Immunology (81 citations) and Physiology (17 citations). Cuifen Hou has collaborated with scholars based in United States and Germany. Frequent co-authors include Montserrat Camps, Peter Gierschik, Karl H. Jakobs, Jeffry B. Stock, Dimitrios N. Sidiropoulos, Monica Singer, Druie Cavender, Dennis Argentieri, Dana L. Johnson and Zhihua Sui. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, ACS Medicinal Chemistry Letters, Journal of Medicinal Chemistry, SLAS DISCOVERY and Journal of Pharmacology and Experimental Therapeutics.

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