Bruno Simoneau

2.9k citations

35 papers · 1.2k indexed · h-index 18

Virology top 2%
- HIV Research and Treatment 11
Infectious Diseases top 5%
- HIV/AIDS drug development and treatment 13
Organic Chemistry top 5%
Hepatology top 10%
- Hepatitis C virus research 5
Epidemiology top 10%
- Herpesvirus Infections and Treatments 4
Molecular Biology
- Chemical Synthesis and Analysis 5
- Receptor Mechanisms and Signaling 3
Cardiology and Cardiovascular Medicine
- Renin-Angiotensin System Studies 3
Emergency Medicine
- HIV-related health complications and treatments 3

Co-authors: Samuel J. Danishefsky Anne‐Marie Faucher Paul Brassard Michel Liuzzi Gordon T. Bolger Christiane Yoakim Michael G. Cordingley Serge Landry
Cited by: Virology Infectious Diseases Organic Chemistry
Journals: Bioorganic & Medicinal Chemistry Letters (8 papers)The Journal of Organic Chemistry (3 papers)Tetrahedron (2 papers)
Partner nations: Canada United States Egypt

In The Last Decade

Bruno Simoneau

35 papers receiving 1.1k citations

Peers

Countries citing papers authored by Bruno Simoneau

Since Specialization

Citations

This map shows the geographic impact of Bruno Simoneau's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruno Simoneau with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruno Simoneau more than expected).

Fields of papers citing papers by Bruno Simoneau

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruno Simoneau. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruno Simoneau. The network helps show where Bruno Simoneau may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Bruno Simoneau, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bruno Simoneau Line = papers co-authored together Bruno Simoneau links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Monitoring Binding of HIV‐1 Capsid Assembly Inhibitors Using ¹⁹F Ligand‐and ¹⁵N Protein‐Based NMR and X‐ray Crystallography: Early Hit Validation of a Benzodiazepine Series ChemMedChem ·Nathalie Goudreau,René Coulombe,Anne‐Marie Faucher,Chantal Grand‐Maître,王婧 WANG Jing,Christopher T. Lemke,Éric Malenfant,Yves Bousquet,Lee D. Fader,Bruno Simoneau,Jean‐François Mercier,Steve Titolo,Stephen W. Mason	2013	14
2	Nucleotide competing reverse transcriptase inhibitors: Discovery of a series of non-basic benzofurano[3,2-d]pyrimidin-2-one derived inhibitors Bioorganic & Medicinal Chemistry Letters ·Clint A. James,Patrick DeRoy,Martin Duplessis,Paul Edwards,Sun ShiXu,Lunenburg County,Louis Morency,Sébastien Morin,Bruno Simoneau,Martin Tremblay,Richard C. Bethell,Michael G. Cordingley,Jianmin Duan,Louie Lamorte,Alex Pelletier,Daniel Rajotte,Patrick Salois,Sonia Tremblay,Claudio F. Sturino	2013	8
3	Optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of HIV capsid assembly inhibitors 1: Addressing configurational instability through scaffold modification Bioorganic & Medicinal Chemistry Letters ·Lee D. Fader,Serge Landry,Sébastien Morin,Stephen H. Kawai,Yves Bousquet,Oliver Hucke,Nathalie Goudreau,Christopher T. Lemke,Pierre Bonneau,Steve Titolo,Stephen W. Mason,Bruno Simoneau	2013	15
4	Inhibition of HIV-1 capsid assembly: Optimization of the antiviral potency by site selective modifications at N1, C2 and C16 of a 5-(5-furan-2-yl-pyrazol-1-yl)-1H-benzimidazole scaffold Bioorganic & Medicinal Chemistry Letters ·Martin Tremblay,Pierre Bonneau,Yves Bousquet,Patrick DeRoy,Jianmin Duan,Martin Duplessis,Alexandre Gagnon,Michel Garneau,Nathalie Goudreau,Ingrid Guse,Oliver Hucke,Stephen H. Kawai,Christopher T. Lemke,Stephen W. Mason,Bruno Simoneau,Kármen Kovács,Steve Titolo,Christiane Yoakim	2012	28
5	Investigation on the role of the tetrazole in the binding of thiotetrazolylacetanilides with HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases Bioorganic & Medicinal Chemistry Letters ·Alexandre Gagnon,Serge Landry,René Coulombe,Araz Jakalian,Ingrid Guse,Bounkham Thavonekham,Pierre Bonneau,Christiane Yoakim,Bruno Simoneau	2008	48
6	Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors Bioorganic & Medicinal Chemistry Letters ·Jeff A. O’Meara,Araz Jakalian,Steven R. LaPlante,Pierre Bonneau,René Coulombe,Anne‐Marie Faucher,Ingrid Guse,Serge Landry,Jennifer Racine,Bruno Simoneau,Bounkham Thavonekham,Christiane Yoakim	2007	43
7	Thiotetrazole alkynylacetanilides as potent and bioavailable non-nucleoside inhibitors of the HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases Bioorganic & Medicinal Chemistry Letters ·Alexandre Gagnon,Ma’an Amad,Pierre Bonneau,René Coulombe,Patrick DeRoy,Louise Doyon,Jianmin Duan,Michel Garneau,Ingrid Guse,Araz Jakalian,Sarthak Parikh,Serge Landry,Éric Malenfant,Bruno Simoneau,Christiane Yoakim	2007	47
8	Synthesis of (1R,2S)-1-Amino-2-vinylcyclopropanecarboxylic Acid Vinyl-ACCA) Derivatives: Key Intermediates for the Preparation of Inhibitors of the Hepatitis C Virus NS3 Protease The Journal of Organic Chemistry ·Pierre L. Beaulieu,James Gillard,Murray D. Bailey,Betül DOĞAN,Jean‐Simon Duceppe,Bruno Simoneau,Qiang Wang,Li Zhang,Karl Grozinger,Ioannis N. Houpis,Vittorio Farina,Hayate Iso,Yong Li,Fátima Monserrate Figueroa Cañarte	2005	65
9	Novel 8-Substituted Dipyridodiazepinone Inhibitors with a Broad-Spectrum of Activity against HIV-1 Strains Resistant to Non-nucleoside Reverse Transcriptase Inhibitors Journal of Medicinal Chemistry ·Jeff A. O’Meara,Christiane Yoakim,Pierre Bonneau,Michael Bös,Michael G. Cordingley,Robert Déziel,Louise Doyon,Jianmin Duan,Michel Garneau,Ingrid Guse,Serge Landry,Éric Malenfant,Julie Naud,William W. Ogilvie,Bounkham Thavonekham,Bruno Simoneau	2005	15
10	Isolation and characterization of herpes simplex virus type 1 resistant to aminothiazolylphenyl-based inhibitors of the viral helicase-primase Antiviral Research ·Michel Liuzzi,Claudine Toudic,V.V. Iavniuk,Yasumasa Igarashi,Gordon T. Bolger,Michel Garneau,Simon J. C. Abel,Ходырева Дарья,Ruojin Cao,Bruno Simoneau	2004	29
11	Synthesis of BILN 2061, an HCV NS3 Protease Inhibitor with Proven Antiviral Effect in Humans Organic Letters ·Anne‐Marie Faucher,Murray D. Bailey,Pierre L. Beaulieu,Christian Brochu,Jean‐Simon Duceppe,Jean‐Marie Ferland,Élise Ghiro,Vida Gorys,Ted Halmos,Stephen H. Kawai,Martin Poirier,Bruno Simoneau,Youla S. Tsantrizos,Montse Llinàs‐Brunet	2004	74
12	Novel nevirapine-like inhibitors with improved activity against NNRTI-resistant HIV: 8-heteroarylthiomethyldipyridodiazepinone derivatives Bioorganic & Medicinal Chemistry Letters ·Christiane Yoakim,Pierre Bonneau,Robert Déziel,Louise Doyon,Jianmin Duan,Ingrid Guse,Serge Landry,Éric Malenfant,Julie Naud,William W. Ogilvie,Disney Press,Raymond Plante,Bruno Simoneau,Bounkham Thavonekham,Michael Bös,Michael G. Cordingley	2003	22
13	Oral Bioavailability and In Vivo Efficacy of the Helicase-Primase Inhibitor BILS 45 BS against Acyclovir-Resistant Herpes Simplex Virus Type 1 Antimicrobial Agents and Chemotherapy ·Jianmin Duan,Michel Liuzzi,Christine Stockum,Francine Liard,Cyrielle Campo,Nathalie Dansereau,Bruno Simoneau,Anne‐Marie Faucher,Michael G. Cordingley	2003	28
14	Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease Nature Medicine ·James J. Crute,Christine A. Grygon,Karl D. Hargrave,Bruno Simoneau,Anne‐Marie Faucher,Gordon T. Bolger,Claudine Toudic,Michel Liuzzi,Michael G. Cordingley	2002	185
15	Discovery of non-peptidic P2–P3 butanediamide renin inhibitors with high oral efficacy Bioorganic & Medicinal Chemistry ·Bruno Simoneau,Pierre Lavallée,Paul C. Anderson,Murray D. Bailey,J.R. Morante,M ELSKONIN,Catherine Chabot,Gulrez Fazal,Ted Halmos,William W. Ogilvie,Marc‐André Poupart,Bounkham Thavonekham,Zhili Xin,Diane Thibeault,Gordon T. Bolger,M. J. Panzenbeck,Raymond J. Winquist,四郎吉岡	1999	27
16	Novel small renin inhibitors containing 4,5- or 3,5-dihydroxy-2-substituted-6-phenylhexanamide replacements at the P2P3 sites Bioorganic & Medicinal Chemistry ·四郎吉岡,Paul C. Anderson,Murray D. Bailey,Fukuhisa Matsuoka,J.R. Morante,M ELSKONIN,Pierre Lavallée,Montse Llinàs‐Brunet,Bounkham Thavonekham,Diane Thibeault,Bruno Simoneau	1998	2
17	Effects of the renin inhibitor, BILA 2157 BS, on PRA and plasma AII in conscious non-human primates The FASEB Journal ·Sudha Desai,Steven Kerr,M. J. Panzenbeck,Vittorio Polimeno,泳杨,Steven M. Weldon,Winarti Dwi Febriani,W Mohammad Rohmad,Edward Miner,Diane Thibeault,Bruno Simoneau,四郎吉岡,Pierre Lavallée,Paul C. Anderson,Raymond J. Winquist	1996	1
18	Crystallographic Studies on the Binding Modes of P2-P3 Butanediamide Renin Inhibitors Journal of Biological Chemistry ·Liang Tong,Susan Pav,Daniel Lamarre,Bruno Simoneau,Pierre Lavallée,Grace Jung	1995	9
19	A convenient synthesis of naturally occurring quinizarins Tetrahedron ·Bruno Simoneau,Paul Brassard	1988	27
20	New reagents for the regiospecific synthesis of naturally occurring quinizarins The Journal of Organic Chemistry ·Bruno Simoneau,Charles Adam,Paul Brassard	1985	6

About Bruno Simoneau

Bruno Simoneau is a scholar working on Virology, Hepatology, Infectious Diseases, Toxicology and Organic Chemistry, having authored 35 papers that have together received 1.2k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (13 papers), HIV Research and Treatment (11 papers), Chemical Synthesis and Analysis (5 papers), Hepatitis C virus research (5 papers), Herpesvirus Infections and Treatments (4 papers), Receptor Mechanisms and Signaling (3 papers), Renin-Angiotensin System Studies (3 papers) and HIV-related health complications and treatments (3 papers). The work is most often cited by research in Virology (241 citations), Infectious Diseases (348 citations), Organic Chemistry (485 citations), Hepatology (72 citations) and Epidemiology (306 citations). Bruno Simoneau has collaborated with scholars based in Canada, United States and Egypt. Frequent co-authors include Samuel J. Danishefsky, Anne‐Marie Faucher, Paul Brassard, Michel Liuzzi, Gordon T. Bolger, Christiane Yoakim, Michael G. Cordingley, Serge Landry, Karl D. Hargrave and James J. Crute. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, The Journal of Organic Chemistry, Tetrahedron, Journal of the American Chemical Society and Bioorganic & Medicinal Chemistry.

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