Lee D. Fader

2.3k total citations · 2 hit papers
19 papers, 1.5k citations indexed

About

Lee D. Fader is a scholar working on Organic Chemistry, Molecular Biology and Infectious Diseases. According to data from OpenAlex, Lee D. Fader has authored 19 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Organic Chemistry, 6 papers in Molecular Biology and 5 papers in Infectious Diseases. Recurrent topics in Lee D. Fader's work include HIV Research and Treatment (5 papers), DNA and Nucleic Acid Chemistry (5 papers) and HIV/AIDS drug development and treatment (5 papers). Lee D. Fader is often cited by papers focused on HIV Research and Treatment (5 papers), DNA and Nucleic Acid Chemistry (5 papers) and HIV/AIDS drug development and treatment (5 papers). Lee D. Fader collaborates with scholars based in Canada, United States and Switzerland. Lee D. Fader's co-authors include Oliver Hucke, Steven R. LaPlante, Paul Edwards, Araz Jakalian, Ray Kemper, Keith R. Fandrick, Daniel R. Fandrick, Stephen Miller, Alexandre Gagnon and Martin Duplessis and has published in prestigious journals such as Journal of Virology, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

In The Last Decade

Lee D. Fader

17 papers receiving 1.5k citations

Hit Papers

Assessing Atropisomer Axial Chirality in Drug Discovery a... 2011 2026 2016 2021 2011 2011 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Assessing Atropisomer Axial Chirality in Drug Discovery and Development
    2011 671 citations Steven R. LaPlante, Lee D. Fader et al. Journal of Medicinal Chemistry profile →
  2. Revealing Atropisomer Axial Chirality in Drug Discovery
    2011 419 citations Steven R. LaPlante, Paul Edwards et al. ChemMedChem profile →

Peers

Lee D. Fader
Oliver Hucke Canada
Wayne J. Thompson United States
Ashit K. Ganguly United States
Willem P. van Hoorn United Kingdom
Siegfried Goldmann Germany
Rama K. Kondru United States
J. V. N. Vara Prasad United States
Susan Sondej Pochapsky United States
Nobuya Katagiri Japan
Douglas J. Minick United States
Oliver Hucke Canada
Lee D. Fader
Citations per year, relative to Lee D. Fader Lee D. Fader (= 1×) peers Oliver Hucke

Countries citing papers authored by Lee D. Fader

Since Specialization
Citations

This map shows the geographic impact of Lee D. Fader's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lee D. Fader with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lee D. Fader more than expected).

Fields of papers citing papers by Lee D. Fader

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lee D. Fader. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lee D. Fader. The network helps show where Lee D. Fader may publish in the future.

Co-authorship network of co-authors of Lee D. Fader

This figure shows the co-authorship network connecting the top 25 collaborators of Lee D. Fader. A scholar is included among the top collaborators of Lee D. Fader based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lee D. Fader. Lee D. Fader is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

19 of 19 papers shown
1.
Cyr, Patrick, Lee D. Fader, Jason D. Burch, et al.. (2024). Discovery of Potent and Orally Bioavailable Pyrimidine Amide cGAS Inhibitors via Structure-Guided Hybridization. ACS Medicinal Chemistry Letters. 15(12). 2201–2209.
2.
Chefson, Amandine, Stéphane Dorich, Jennifer H. Cox, et al.. (2023). Discovery of NXT-10796, an orally active, intestinally restricted EP4 agonist prodrug for the treatment of inflammatory bowel disease. Bioorganic & Medicinal Chemistry Letters. 91. 129351–129351.
3.
Dorich, Stéphane, Jennifer H. Cox, Jason D. Burch, et al.. (2020). Novel pyridone EP4 agonists featuring allylic alcohol ω-chains. Bioorganic & Medicinal Chemistry Letters. 30(10). 127104–127104. 6 indexed citations
4.
Fader, Lee D., Rebekah Carson, Sébastien Morin, et al.. (2014). Minimizing the Contribution of Enterohepatic Recirculation to Clearance in Rat for the NCINI Class of Inhibitors of HIV. ACS Medicinal Chemistry Letters. 5(6). 711–716. 14 indexed citations
5.
Goudreau, Nathalie, René Coulombe, Anne‐Marie Faucher, et al.. (2013). Monitoring Binding of HIV‐1 Capsid Assembly Inhibitors Using 19F Ligand‐and 15N Protein‐Based NMR and X‐ray Crystallography: Early Hit Validation of a Benzodiazepine Series. ChemMedChem. 8(3). 405–414. 14 indexed citations
6.
Fader, Lee D., Serge Landry, Sébastien Morin, et al.. (2013). Optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of HIV capsid assembly inhibitors 1: Addressing configurational instability through scaffold modification. Bioorganic & Medicinal Chemistry Letters. 23(11). 3396–3400. 15 indexed citations
7.
Fader, Lee D., Serge Landry, Sylvie Goulet, et al.. (2013). Optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of HIV capsid assembly inhibitors 2: Structure–activity relationships (SAR) of the C3-phenyl moiety. Bioorganic & Medicinal Chemistry Letters. 23(11). 3401–3405. 16 indexed citations
8.
Kleinbeck, Florian, et al.. (2012). Total Synthesis of Bafilomycin A1. Chemistry - A European Journal. 18(12). 3598–3610. 27 indexed citations
9.
Lemke, Christopher T., Steve Titolo, Uta von Schwedler, et al.. (2012). Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein. Journal of Virology. 86(12). 6643–6655. 102 indexed citations
10.
LaPlante, Steven R., Lee D. Fader, Keith R. Fandrick, et al.. (2011). Assessing Atropisomer Axial Chirality in Drug Discovery and Development. Journal of Medicinal Chemistry. 54(20). 7005–7022. 671 indexed citations breakdown →
11.
LaPlante, Steven R., Paul Edwards, Lee D. Fader, Araz Jakalian, & Oliver Hucke. (2011). Revealing Atropisomer Axial Chirality in Drug Discovery. ChemMedChem. 6(3). 505–513. 419 indexed citations breakdown →
12.
Gagnon, Alexandre, Martin Duplessis, & Lee D. Fader. (2010). Arylcyclopropanes: Properties, Synthesis and Use in Medicinal Chemistry. Organic Preparations and Procedures International. 42(1). 1–69. 106 indexed citations
13.
Forgione, Pat & Lee D. Fader. (2009). ChemInform Abstract: Product Class 3: Propargylic Alcohols. ChemInform. 40(39). 1 indexed citations
14.
Fader, Lee D., Eddie L. Myers, & Youla S. Tsantrizos. (2004). Synthesis of novel analogs of aromatic peptide nucleic acids (APNAs) with modified conformational and electrostatic properties. Tetrahedron. 60(10). 2235–2246. 7 indexed citations
15.
Fader, Lee D. & Erick M. Carreira. (2004). Stereochemically Rich Pentaketides from Bis(isoxazolines):  A General Strategy for Efficient Polyketide Synthesis. Organic Letters. 6(14). 2485–2488. 39 indexed citations
16.
Fader, Lee D. & Youla S. Tsantrizos. (2001). Hybridization Properties of Aromatic Peptide Nucleic Acids:  A Novel Class of Oligonucleotide Analogues. Organic Letters. 4(1). 63–66. 6 indexed citations
17.
Fader, Lee D., Michael J. Boyd, & Youla S. Tsantrizos. (2001). Backbone Modifications of Aromatic Peptide Nucleic Acid (APNA) Monomers and Their Hybridization Properties with DNA and RNA. The Journal of Organic Chemistry. 66(10). 3372–3379. 15 indexed citations
18.
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Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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