Araz Jakalian
About
Araz Jakalian is a scholar working on Infectious Diseases, Hepatology and Molecular Biology.
According to data from OpenAlex, Araz Jakalian has authored 27 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Infectious Diseases, 11 papers in Hepatology and 8 papers in Molecular Biology. Recurrent topics in Araz Jakalian's work include HIV/AIDS drug development and treatment (13 papers), Hepatitis C virus research (11 papers) and Computational Drug Discovery Methods (6 papers). Araz Jakalian is often cited by papers focused on HIV/AIDS drug development and treatment (13 papers), Hepatitis C virus research (11 papers) and Computational Drug Discovery Methods (6 papers). Araz Jakalian collaborates with scholars based in Canada, Germany and United States. Araz Jakalian's co-authors include Christopher I. Bayly, D. B. Jack, Bruce L. Bush, Steven R. LaPlante, Oliver Hucke, Paul Edwards, Lee D. Fader, Kathryn N. Rankin, Enrico O. Purisima and Sathesh Bhat and has published in prestigious journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and The Journal of Chemical Physics.
In The Last Decade
Araz Jakalian
27 papers receiving 5.7k citations
Hit Papers
Peers
Araz Jakalian
James M. Briggs United States
Lillian T. Chong United States
Shuanghong Huo United States
Daniel R. Roe United States
Matthew Clark United States
Lauren Wickstrom United States
Wolfgang Damm United States
Jason Swails United States
Lingle Wang United States
John C. Shelley United States
Citations per year, relative to Araz Jakalian Araz Jakalian (= 1×)
peers
James M. Briggs
Countries citing papers authored by Araz Jakalian
Since
Specialization
Citations
This map shows the geographic impact of Araz Jakalian's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Araz Jakalian with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Araz Jakalian more than expected).
Fields of papers citing papers by Araz Jakalian
Since
Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences
This network shows the impact of papers produced by Araz Jakalian. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Araz Jakalian. The network helps show where Araz Jakalian may publish in the future.
Co-authorship network of co-authors of Araz Jakalian
This figure shows the co-authorship network connecting the top 25 collaborators of Araz Jakalian. A scholar is included among the top collaborators of Araz Jakalian based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Araz Jakalian. Araz Jakalian is excluded from the visualization to improve readability, since they are connected to all nodes in the network.
All Works
1.
Fader, Lee D., Rebekah Carson, Sébastien Morin, et al.. (2014). Minimizing the Contribution of Enterohepatic Recirculation to Clearance in Rat for the NCINI Class of Inhibitors of HIV. ACS Medicinal Chemistry Letters. 5(6). 711–716.
2.
Stammers, Timothy A., René Coulombe, Martin Duplessis, et al.. (2013). Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay. Bioorganic & Medicinal Chemistry Letters. 23(24). 6879–6885.
3.
Stammers, Timothy A., René Coulombe, Jean Rancourt, et al.. (2013). Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors. Bioorganic & Medicinal Chemistry Letters. 23(9). 2585–2589.
4.
Beaulieu, Pierre L., René Coulombe, Jianmin Duan, et al.. (2013). Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype. Bioorganic & Medicinal Chemistry Letters. 23(14). 4132–4140.
5.
LaPlante, Steven R., Michael Bös, Christian Brochu, et al.. (2013). Conformation-Based Restrictions and Scaffold Replacements in the Design of Hepatitis C Virus Polymerase Inhibitors: Discovery of Deleobuvir (BI 207127). Journal of Medicinal Chemistry. 57(5). 1845–1854.
6.
LaPlante, Steven R., Herbert Nar, Christopher T. Lemke, et al.. (2013). Ligand Bioactive Conformation Plays a Critical Role in the Design of Drugs That Target the Hepatitis C Virus NS3 Protease. Journal of Medicinal Chemistry. 57(5). 1777–1789.
7.
LaPlante, Steven R., Paul Edwards, Lee D. Fader, Araz Jakalian, & Oliver Hucke. (2011). Revealing Atropisomer Axial Chirality in Drug Discovery. ChemMedChem. 6(3). 505–513.
8.
Beaulieu, Pierre L., James Gillard, Christian Brochu, et al.. (2010). N-Acetamideindolecarboxylic acid allosteric ‘finger-loop’ inhibitors of the hepatitis C virus NS5B polymerase: discovery and initial optimization studies. Bioorganic & Medicinal Chemistry Letters. 20(3). 857–861.
9.
Böcker, Alexander, Pierre Bonneau, Oliver Hucke, Araz Jakalian, & Paul Edwards. (2010). Development of Specific “Drug‐Like Property” Rules for Carboxylate‐Containing Oral Drug Candidates. ChemMedChem. 5(12). 2102–2113.
10.
LaPlante, Steven R., James Gillard, Araz Jakalian, et al.. (2010). Importance of Ligand Bioactive Conformation in the Discovery of Potent Indole-Diamide Inhibitors of the Hepatitis C Virus NS5B. Journal of the American Chemical Society. 132(43). 15204–15212.
11.
Gagnon, Alexandre, Serge Landry, René Coulombe, et al.. (2008). Investigation on the role of the tetrazole in the binding of thiotetrazolylacetanilides with HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases. Bioorganic & Medicinal Chemistry Letters. 19(4). 1199–1205.
12.
Goudreau, Nathalie, Dale R. Cameron, Robert Déziel, et al.. (2007). Optimization and determination of the absolute configuration of a series of potent inhibitors of human papillomavirus type-11 E1–E2 protein–protein interaction: A combined medicinal chemistry, NMR and computational chemistry approach. Bioorganic & Medicinal Chemistry. 15(7). 2690–2700.
13.
O’Meara, Jeff A., Araz Jakalian, Steven R. LaPlante, et al.. (2007). Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(12). 3362–3366.
14.
Muzammil, Salman, Anthony A. Armstrong, Lin‐Woo Kang, et al.. (2007). Unique Thermodynamic Response of Tipranavir to Human Immunodeficiency Virus Type 1 Protease Drug Resistance Mutations. Journal of Virology. 81(10). 5144–5154.
15.
Gagnon, Alexandre, Ma’an Amad, Pierre Bonneau, et al.. (2007). Thiotetrazole alkynylacetanilides as potent and bioavailable non-nucleoside inhibitors of the HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases. Bioorganic & Medicinal Chemistry Letters. 17(16). 4437–4441.
16.
Beaulieu, Pierre L., James Gillard, Christian Brochu, et al.. (2006). Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds. Bioorganic & Medicinal Chemistry Letters. 16(19). 4987–4993.
17.
LaPlante, Steven R., Araz Jakalian, Norman Aubry, et al.. (2004). Binding Mode Determination of Benzimidazole Inhibitors of the Hepatitis C Virus RNA Polymerase by a Structure and Dynamics Strategy. Angewandte Chemie International Edition. 43(33). 4306–4311.
18.
LaPlante, Steven R., Araz Jakalian, Norman Aubry, et al.. (2004). Binding Mode Determination of Benzimidazole Inhibitors of the Hepatitis C Virus RNA Polymerase by a Structure and Dynamics Strategy. Angewandte Chemie. 116(33). 4406–4411.
19.
Jakalian, Araz, D. B. Jack, & Christopher I. Bayly. (2002). Fast, efficient generation of high‐quality atomic charges. AM1‐BCC model: II. Parameterization and validation. Journal of Computational Chemistry. 23(16). 1623–1641.
20.
Jakalian, Araz, Bruce L. Bush, D. B. Jack, & Christopher I. Bayly. (2000). Fast, efficient generation of high-quality atomic charges. AM1-BCC model: I. Method. Journal of Computational Chemistry. 21(2). 132–132.
Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.
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