James Gillard

1.3k citations

30 papers · 975 indexed · h-index 19

Impact in

Hepatology top 2%
- Hepatitis C virus research
Organic Chemistry top 5%
- Synthesis and biological activity
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis

Papers in

Hepatology 18
- Hepatitis C virus research 18
Infectious Diseases 20
- HIV/AIDS drug development and treatment 20

Co-authors: Pierre L. Beaulieu George Kukolj Yves Bousquet D. Jean Burnell Ginette McKercher Steven R. LaPlante Marc‐André Poupart Jean Gauthier
Journals: Bioorganic & Medicinal Chemistry Letters (9 papers)Journal of Medicinal Chemistry (7 papers)The Journal of Organic Chemistry (4 papers)Canadian Journal of Chemistry (3 papers)Molecular Pharmaceutics (1 paper)
Partner nations: Canada Germany Egypt

In The Last Decade

James Gillard

29 papers receiving 938 citations

Peers

Countries citing papers authored by James Gillard

Since Specialization

Citations

This map shows the geographic impact of James Gillard's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Gillard with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Gillard more than expected).

Fields of papers citing papers by James Gillard

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Gillard. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Gillard. The network helps show where James Gillard may publish in the future.

Co-authorship network

The 25 scholars most cited alongside James Gillard, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James Gillard Line = papers co-authored together James Gillard links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Drug Self-Aggregation into Nano-Entities Has the Potential to Induce Immune Responses Molecular Pharmaceutics ·Sultan Nashir Ibnu, el-Okle Ma, Li Li, James Gillard, Denis Girard, Steven R. LaPlante	2023	3
2	Discovery of BI 207524, an Indole Diamide NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection Journal of Medicinal Chemistry ·Pierre L. Beaulieu, Paul C. Anderson, Richard C. Bethell, Michael Bös, Yves Bousquet, Christian Brochu, Michael G. Cordingley, Gulrez Fazal, Michel Garneau, James Gillard, Stephen H. Kawai, Martin Marquis, Ginette McKercher, Marc‐André Poupart, Timothy A. Stammers, Bounkham Thavonekham, Dominik Wernic, Jianmin Duan, George Kukolj	2014	10
3	N- versus O-alkylation: Utilizing NMR methods to establish reliable primary structure determinations for drug discovery Bioorganic & Medicinal Chemistry Letters ·Steven R. LaPlante, François Bilodeau, Norman Aubry, James Gillard, Jeff A. O’Meara, René Coulombe	2013	16
4	Conformation-Based Restrictions and Scaffold Replacements in the Design of Hepatitis C Virus Polymerase Inhibitors: Discovery of Deleobuvir (BI 207127) Journal of Medicinal Chemistry ·Steven R. LaPlante, Michael Bös, Christian Brochu, Catherine Chabot, René Coulombe, James Gillard, Araz Jakalian, Martin Poirier, Jean Rancourt, Timothy A. Stammers, Bounkham Thavonekham, Pierre L. Beaulieu, George Kukolj, Youla S. Tsantrizos	2013	27
5	Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronically Infected with Genotype 1 Hepatitis C Virus (HCV) Journal of Medicinal Chemistry ·Pierre L. Beaulieu, Michael Bös, Michael G. Cordingley, Catherine Chabot, Gulrez Fazal, Michel Garneau, James Gillard, Sarthak Parikh, Steven R. LaPlante, Ginette McKercher, Martin Poirier, Marc‐André Poupart, Youla S. Tsantrizos, Jianmin Duan, George Kukolj	2012	36
6	From benzimidazole to indole-5-carboxamide Thumb Pocket I inhibitors of HCV NS5B polymerase. Part 1: Indole C-2 SAR and discovery of diamide derivatives with nanomolar potency in cell-based subgenomic replicons Bioorganic & Medicinal Chemistry Letters ·Pierre L. Beaulieu, James Gillard, Sarthak Parikh, Jianmin Duan, Michel Garneau, George Kukolj, Marc‐André Poupart	2011	18
7	Indole 5-carboxamide Thumb Pocket I inhibitors of HCV NS5B polymerase with nanomolar potency in cell-based subgenomic replicons (part 2): Central amino acid linker and right-hand-side SAR studies Bioorganic & Medicinal Chemistry Letters ·Pierre L. Beaulieu, Catherine Chabot, Jianmin Duan, Michel Garneau, James Gillard, Sarthak Parikh, Martin Poirier, Marc‐André Poupart, Timothy A. Stammers, George Kukolj, Youla S. Tsantrizos	2011	7
8	N-Acetamideindolecarboxylic acid allosteric ‘finger-loop’ inhibitors of the hepatitis C virus NS5B polymerase: discovery and initial optimization studies Bioorganic & Medicinal Chemistry Letters ·Pierre L. Beaulieu, Sarthak Parikh, James Gillard, Christian Brochu, René Coulombe, Nathalie Dansereau, Jianmin Duan, Michel Garneau, Araz Jakalian, Peter Kühn, Lisette Lagacé, Steven R. LaPlante, Ginette McKercher, 直子森本, Martin Poirier, Marc‐André Poupart, Timothy A. Stammers, Louise Thauvette, Bounkham Thavonekham, George Kukolj	2010	12
9	Benzimidazole Thumb Pocket I finger-loop inhibitors of HCV NS5B polymerase: Improved drug-like properties through C-2 SAR in three sub-series Bioorganic & Medicinal Chemistry Letters ·Pierre L. Beaulieu, Nathalie Dansereau, Jianmin Duan, Michel Garneau, James Gillard, Ginette McKercher, Steven R. LaPlante, D.P. Morales, Louise Thauvette, George Kukolj	2010	8
10	Importance of Ligand Bioactive Conformation in the Discovery of Potent Indole-Diamide Inhibitors of the Hepatitis C Virus NS5B Journal of the American Chemical Society ·Steven R. LaPlante, James Gillard, Araz Jakalian, Norman Aubry, René Coulombe, Christian Brochu, Youla S. Tsantrizos, Martin Poirier, George Kukolj, Pierre L. Beaulieu	2010	34
11	Discovery of benzimidazole-diamide finger loop (Thumb Pocket I) allosteric inhibitors of HCV NS5B polymerase: Implementing parallel synthesis for rapid linker optimization Bioorganic & Medicinal Chemistry Letters ·Sylvie Goulet, Marc‐André Poupart, James Gillard, Martin Poirier, George Kukolj, Pierre L. Beaulieu	2009	18
12	Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds Bioorganic & Medicinal Chemistry Letters ·Pierre L. Beaulieu, James Gillard, Esra Eryaman, Christian Brochu, Nathalie Dansereau, Jean‐Simon Duceppe, Bruno Haché, Araz Jakalian, Lisette Lagacé, Steven R. LaPlante, Ginette McKercher, Maya Eka Purwanti, Stéphane Perreault, Timothy A. Stammers, Louise Thauvette, 王其和, George Kukolj	2006	58
13	Synthesis of (1R,2S)-1-Amino-2-vinylcyclopropanecarboxylic Acid Vinyl-ACCA) Derivatives: Key Intermediates for the Preparation of Inhibitors of the Hepatitis C Virus NS3 Protease The Journal of Organic Chemistry ·Pierre L. Beaulieu, James Gillard, Murray D. Bailey, Betül DOĞAN, Jean‐Simon Duceppe, Bruno Simoneau, Qiang Wang, Li Zhang, Karl Grozinger, Ioannis N. Houpis, Vittorio Farina, Hayate Iso, Yong Li, Fátima Monserrate Figueroa Cañarte	2005	65
14	Binding Mode Determination of Benzimidazole Inhibitors of the Hepatitis C Virus RNA Polymerase by a Structure and Dynamics Strategy Angewandte Chemie International Edition ·Steven R. LaPlante, Araz Jakalian, Norman Aubry, Yves Bousquet, Jean‐Marie Ferland, James Gillard, Sylvain Lefèbvre, Martin Poirier, Youla S. Tsantrizos, George Kukolj, Pierre L. Beaulieu	2004	45
15	Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency Bioorganic & Medicinal Chemistry Letters ·Pierre L. Beaulieu, Michael Bös, Yves Bousquet, Patrick DeRoy, Gulrez Fazal, Jean Gauthier, James Gillard, Sylvie Goulet, Ginette McKercher, Marc‐André Poupart, Arina Nur. Ngaini, George Kukolj	2004	74
16	Binding Mode Determination of Benzimidazole Inhibitors of the Hepatitis C Virus RNA Polymerase by a Structure and Dynamics Strategy Angewandte Chemie ·Steven R. LaPlante, Araz Jakalian, Norman Aubry, Yves Bousquet, Jean‐Marie Ferland, James Gillard, Sylvain Lefèbvre, Martin Poirier, Youla S. Tsantrizos, George Kukolj, Pierre L. Beaulieu	2004	4
17	Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives Bioorganic & Medicinal Chemistry Letters ·Pierre L. Beaulieu, Michael Bös, Yves Bousquet, Gulrez Fazal, Jean Gauthier, James Gillard, Sylvie Goulet, Steven R. LaPlante, Marc‐André Poupart, Sylvain Lefèbvre, Ginette McKercher, Charles Pellerin, Volkhard Austel, George Kukolj	2003	82
18	Practical Synthesis of BILA 2157 BS, a Potent and Orally Active Renin Inhibitor: Use of an Enzyme-Catalyzed Hydrolysis for the Preparation of Homochiral Succinic Acid Derivatives The Journal of Organic Chemistry ·Pierre L. Beaulieu, James Gillard, Murray D. Bailey, Christian Beaulieu, Jean‐Simon Duceppe, Pierre Lavallée, Dominik Wernic	1999	25
19	ChemInform Abstract: Practical, Stereoselective Synthesis of Palinavir, a Potent HIV Protease Inhibitor. ChemInform ·宮川治雄, Pierre Lavallée, Annamma Abraham, Paul C. Anderson, 眞良新谷, Streatfield Kim, Jean‐Simon Duceppe, James Gillard, Vida Gorys, Chantal Grand‐Maître, Louis Grenier, Yvan Guindon, Ingrid Guse, Louis Plamondon, Наталья Николаевна Кривоногова, Arina Nur. Ngaini, Dominik Wernic, Christiane Yoakim	1997	1
20	π-Facial stereoselectivity in the Diels–Alder reactions of benzene oxides Canadian Journal of Chemistry ·James Gillard, M. J. Newlands, John N. Bridson, D. Jean Burnell	1991	41

About James Gillard

James Gillard is a scholar working on Hepatology, Infectious Diseases, Virology, Organic Chemistry and Radiology, Nuclear Medicine and Imaging, having authored 30 papers that have together received 975 indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (20 papers), Hepatitis C virus research (18 papers), Hepatitis B Virus Studies (7 papers), Monoclonal and Polyclonal Antibodies Research (6 papers), Asymmetric Synthesis and Catalysis (5 papers), Biochemical and Molecular Research (5 papers), Chemical Synthesis and Analysis (3 papers) and HIV Research and Treatment (3 papers). The work is most often cited by research in Hepatology (330 citations), Organic Chemistry (469 citations), Infectious Diseases (273 citations), Virology (29 citations) and Epidemiology (177 citations). James Gillard has collaborated with scholars based in Canada, Germany and Egypt. Frequent co-authors include Pierre L. Beaulieu, George Kukolj, Yves Bousquet, D. Jean Burnell, Ginette McKercher, Steven R. LaPlante, Marc‐André Poupart, Jean Gauthier, René Coulombe and Norman Aubry. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, The Journal of Organic Chemistry, Canadian Journal of Chemistry and Molecular Pharmaceutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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