Brian Scott

1.2k citations

24 papers · 1.0k indexed · h-index 15

Impact in

Physiology top 5%
- Pain Mechanisms and Treatments
- Adenosine and Purinergic Signaling
Toxicology top 5%

Papers in ⓘ

Toxicology 3
Physiology 3
- Adenosine and Purinergic Signaling 3
- Asthma and respiratory diseases 3

Co-authors: Bin Jiang (1 shared paper)Paul S. Watson (1 shared paper)Sandra R. Chaplan (13 shared papers)J. Guy Breitenbucher (11 shared papers)Michael Webb (9 shared papers)Stephen B. McMahon (1 shared paper)Z. David Luo (1 shared paper)Nigel A. Calcutt (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (11 papers)ACS Medicinal Chemistry Letters (3 papers)Journal of Medicinal Chemistry (3 papers)Journal of Pharmacology and Experimental Therapeutics (1 paper)Anesthesia & Analgesia (1 paper)
Partner nations: United States United Kingdom Australia

In The Last Decade

Brian Scott

24 papers receiving 987 citations

Peers

Countries citing papers authored by Brian Scott

Since Specialization

Citations

This map shows the geographic impact of Brian Scott's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian Scott with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian Scott more than expected).

Fields of papers citing papers by Brian Scott

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian Scott. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian Scott. The network helps show where Brian Scott may publish in the future.

Co-authors

The 25 scholars most cited alongside Brian Scott, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Brian Scott Line = papers co-authored together Brian Scott links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 24 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A Diastereoselective Synthesis of 2,4-Disubstituted Piperidines: Scaffolds for Drug Discovery Organic Letters ·Paul S. Watson, Bin Jiang, Brian Scott	2000	279
2	Regulation of Expression of the Sensory Neuron-Specific Sodium Channel SNS in Inflammatory and Neuropathic Pain Molecular and Cellular Neuroscience ·Kenji Okuse, Sandra R. Chaplan, Stephen B. McMahon, Z. David Luo, Nigel A. Calcutt, Brian Scott, Armen N. Akopian, John N. Wood	1997	135
3	Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase Bioorganic & Medicinal Chemistry Letters ·John M. Keith, Richard L. Apodaca, Wei Xiao, Mark Seierstad, Kanaka Pattabiraman, Jiejun Wu, Michael Webb, Mark J. Karbarz, Sean M. Brown, Sandy Wilson, Brian Scott, Chui‐Se Tham, Lin Luo, James A. Palmer, Michelle Wennerholm, Sandra R. Chaplan, J. Guy Breitenbucher	2008	76
4	Pharmacology and Antitussive Efficacy of 4-(3-Trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic Acid (5-Trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a Transient Receptor Potential Vanilloid 1 Antagonist in Guinea Pigs Journal of Pharmacology and Experimental Therapeutics ·Anindya Bhattacharya, Brian Scott, Nadia Nasser, Hong Ao, Michael P. Maher, Adrienne E. Dubin, Devin M. Swanson, Nigel P. Shankley, Alan D. Wickenden, Sandra R. Chaplan	2007	62
5	Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase Anesthesia & Analgesia ·Mark J. Karbarz, Lin Luo, Leon Chang, Chui‐Se Tham, James A. Palmer, Sandy J. Wilson, Michelle Wennerholm, Sean M. Brown, Brian Scott, Richard L. Apodaca, John M. Keith, Jiejun Wu, J. Guy Breitenbucher, Sandra R. Chaplan, Michael Webb	2008	61
6	A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate Journal of Medicinal Chemistry ·Christa C. Chrovian, Akinola Soyode-Johnson, Alexander A. Peterson, Christine F. Gelin, Xiaohu Deng, Curt A. Dvorak, Nicholas I. Carruthers, Brian Lord, Ian Fraser, Leah Aluisio, Kevin J. Coe, Brian Scott, Tatiana Koudriakova, Freddy Schoetens, Kia Sepassi, David J. Gallacher, Anindya Bhattacharya, Michael A. Letavic	2017	60
7	Preclinical Characterization of the FAAH Inhibitor JNJ-42165279 ACS Medicinal Chemistry Letters ·John M. Keith, W. M. Jones, Mark S. Tichenor, Jing Liu, Mark Seierstad, James A. Palmer, Michael Webb, Mark J. Karbarz, Brian Scott, Sandy J. Wilson, Lin Luo, Michelle Wennerholm, Leon Chang, Michèle Rizzolio, Raymond Rynberg, Sandra R. Chaplan, J. Guy Breitenbucher	2015	47
8	Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X₇ Antagonists ACS Medicinal Chemistry Letters ·Michael A. Letavic, Brian Lord, François Bischoff, Natalie A. Hawryluk, Serge Pieters, Jason C. Rech, Zachary S. Sales, Adriana I. Velter, Hong Ao, Pascal Bonaventure, Víctor Contreras, Xiaohui Jiang, Kirsten L. Morton, Brian Scott, Qi Wang, Alan D. Wickenden, Nicholas I. Carruthers, Anindya Bhattacharya	2013	39
9	Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate ACS Medicinal Chemistry Letters ·John M. Keith, Richard L. Apodaca, Mark S. Tichenor, Wei Xiao, W. M. Jones, Joan M. Pierce, Mark Seierstad, James A. Palmer, Michael Webb, Mark J. Karbarz, Brian Scott, Sandy Wilson, Lin Luo, Michelle Wennerholm, Leon Chang, Sean M. Brown, Michèle Rizzolio, Raymond Rynberg, Sandra R. Chaplan, J. Guy Breitenbucher	2012	31
10	Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor Journal of Medicinal Chemistry ·Devin M. Swanson, Brad M. Savall, Kevin J. Coe, Freddy Schoetens, Tatiana Koudriakova, Judith Skaptason, Jessica L. Wall, Jason C. Rech, Xiahou Deng, Meri De Angelis, Anita Everson, Brian Lord, Qi Wang, Hong Ao, Brian Scott, Kia Sepassi, Timothy W. Lovenberg, Nicholas I. Carruthers, Anindya Bhattacharya, Michael A. Letavic	2016	30
11	Targeting the Ion Channel Kv1.3 with Scorpion Venom Peptides Engineered for Potency, Selectivity, and Half-life Journal of Biological Chemistry ·Wilson B. Edwards, Wai‐Ping Fung‐Leung, Chichi Huang, Ellen Chi, Nancy Wu, Yi Liu, Michael P. Maher, Rachelle Bonesteel, Judith Connor, Ross Fellows, Elena Alexandra Garcia, Jerry Lee, Lu Lu, Karen Ngo, Brian Scott, Hong Zhou, Ronald V. Swanson, Alan D. Wickenden	2014	26
12	Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH) Bioorganic & Medicinal Chemistry Letters ·Amy Timmons, Mark Seierstad, Richard L. Apodaca, Matt Epperson, Dan Pippel, Sean M. Brown, Leon Chang, Brian Scott, Michael Webb, Sandra R. Chaplan, J. Guy Breitenbucher	2008	25
13	Heteroarylureas with spirocyclic diamine cores as inhibitors of fatty acid amide hydrolase Bioorganic & Medicinal Chemistry Letters ·John M. Keith, W. M. Jones, Joan M. Pierce, Mark Seierstad, James A. Palmer, Michael Webb, Mark J. Karbarz, Brian Scott, Sandy J. Wilson, Lin Luo, Michelle Wennerholm, Leon Chang, Sean M. Brown, Michèle Rizzolio, Raymond Rynberg, Sandra R. Chaplan, J. Guy Breitenbucher	2014	24
14	Towards novel biolabels: synthesis of a tagged highly fluorescent Schiff-base aluminium complex Tetrahedron Letters ·M. Briggs, John Fossey, Christopher J. Richards, Brian Scott, John Whateley	2002	21
15	Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists Bioorganic & Medicinal Chemistry Letters ·Alec D. Lebsack, Bryan J. Branstetter, Michael D. Hack, Wei Xiao, Matthew L. Peterson, Nadia Nasser, Michael P. Maher, Hong Ao, Anindya Bhattacharya, Mena Kansagara, Brian Scott, Lin Luo, Raymond Rynberg, Michèle Rizzolio, Sandra R. Chaplan, Alan D. Wickenden, J. Guy Breitenbucher	2008	18
16	Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach Bioorganic & Medicinal Chemistry Letters ·Christoph Steeneck, Christian Gege, Olaf Kinzel, M. Albers, Gerald Kleymann, Thomas Schlüter, Andreas Schulz, Xiaohua Xue, Maxwell D. Cummings, Anne M. Fourie, Kristi Leonard, Brian Scott, James P. Edwards, Thomas K. Hoffmann, Steven D. Goldberg	2020	14
17	The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors Bioorganic & Medicinal Chemistry Letters ·John M. Keith, Mark S. Tichenor, Richard L. Apodaca, Wei Xiao, W. M. Jones, Mark Seierstad, Joan M. Pierce, James A. Palmer, Michael Webb, Mark J. Karbarz, Brian Scott, Sandy J. Wilson, Michelle Wennerholm, Michèle Rizzolio, Raymond Rynberg, Sandra R. Chaplan, J. Guy Breitenbucher	2016	11
18	1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase Bioorganic & Medicinal Chemistry Letters ·John M. Keith, Natalie A. Hawryluk, Richard L. Apodaca, Allison Chambers, Joan M. Pierce, Mark Seierstad, James A. Palmer, Michael Webb, Mark J. Karbarz, Brian Scott, Sandy J. Wilson, Lin Luo, Michelle Wennerholm, Leon Chang, Michèle Rizzolio, Sandra R. Chaplan, J. Guy Breitenbucher	2014	11
19	Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt Bioorganic & Medicinal Chemistry Letters ·Christian Gege, M. Albers, Olaf Kinzel, Gerald Kleymann, Thomas Schlüter, Christoph Steeneck, Thomas K. Hoffmann, Xiaohua Xue, Maxwell D. Cummings, John Spurlino, Cynthia Milligan, Anne M. Fourie, James P. Edwards, Kristi Leonard, Kevin J. Coe, Brian Scott, Dan Pippel, Steven D. Goldberg	2020	10
20	3-Substituted Quinolines as RORγt Inverse Agonists Bioorganic & Medicinal Chemistry Letters ·Virginia M. Tanis, Hariharan Venkatesan, Maxwell D. Cummings, M. Albers, J. Kent Barbay, Krystal Herman, David A. Kummer, Cynthia Milligan, Marina I. Nelen, Rachel T. Nishimura, Thomas Schlueter, Brian Scott, John Spurlino, Ronald Wolin, Craig R. Woods, Xiaohua Xue, James P. Edwards, Anne M. Fourie, Kristi Leonard	2019	9

About Brian Scott

Brian Scott is a scholar working on Toxicology, Physiology, Sensory Systems, Pharmacology and Biological Psychiatry, having authored 24 papers that have together received 1.0k indexed citations. Recurring topics across this work include Cannabis and Cannabinoid Research (9 papers), Alcohol Consumption and Health Effects (5 papers), Adenosine and Purinergic Signaling (3 papers), Asthma and respiratory diseases (3 papers), Neurotransmitter Receptor Influence on Behavior (3 papers), Pharmacological Receptor Mechanisms and Effects (3 papers), Psoriasis: Treatment and Pathogenesis (3 papers) and Ion Channels and Receptors (3 papers). The work is most often cited by research in Physiology (96 citations), Toxicology (57 citations), Pharmacology (244 citations), Organic Chemistry (401 citations) and Sensory Systems (65 citations). Brian Scott has collaborated with scholars based in United States, United Kingdom and Australia. Frequent co-authors include Bin Jiang, Paul S. Watson, Sandra R. Chaplan, J. Guy Breitenbucher, Michael Webb, Stephen B. McMahon, Z. David Luo, Nigel A. Calcutt, Armen N. Akopian and Kenji Okuse. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, ACS Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics and Anesthesia & Analgesia.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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