Brian Lord

3.4k citations

65 papers · 2.6k indexed · h-index 31

Impact in

Physiology top 0.5%
- Adenosine and Purinergic Signaling
Biological Psychiatry top 2%
- Tryptophan and brain disorders

Papers in ⓘ

Molecular Biology 33
- Receptor Mechanisms and Signaling 18
- Phenothiazines and Benzothiazines Synthesis and Activities 9
Cellular and Molecular Neuroscience 21
- Neuroscience and Neuropharmacology Research 12

Co-authors: Timothy W. Lovenberg (37 shared papers)Nicholas I. Carruthers (42 shared papers)Pascal Bonaventure (36 shared papers)Leah Aluisio (19 shared papers)Michael A. Letavic (31 shared papers)Christine Dugovic (16 shared papers)Ian Fraser (16 shared papers)Anindya Bhattacharya (15 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (13 papers)ACS Medicinal Chemistry Letters (8 papers)Journal of Pharmacology and Experimental Therapeutics (7 papers)Journal of Medicinal Chemistry (7 papers)European Journal of Pharmacology (6 papers)
Partner nations: United States Belgium Netherlands

In The Last Decade

Brian Lord

64 papers receiving 2.5k citations

Peers

Countries citing papers authored by Brian Lord

Since Specialization

Citations

This map shows the geographic impact of Brian Lord's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian Lord with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian Lord more than expected).

Fields of papers citing papers by Brian Lord

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian Lord. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian Lord. The network helps show where Brian Lord may publish in the future.

Co-authors

The 25 scholars most cited alongside Brian Lord, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Brian Lord Line = papers co-authored together Brian Lord links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 65 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat Journal of Pharmacology and Experimental Therapeutics ·Christine Dugovic, Jonathan Shelton, Leah Aluisio, Ian Fraser, Xiaohui Jiang, Steven W. Sutton, Pascal Bonaventure, Sujin Yun, Xiaorong Li, Brian Lord, Curt A. Dvorak, Nicholas I. Carruthers, Timothy W. Lovenberg	2009	186
2	Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ‐47965567 British Journal of Pharmacology ·Anindya Bhattacharya, Qi Wang, Hong Ao, James R. Shoblock, Brian Lord, Leah Aluisio, Ian Fraser, Diane Nepomuceno, Robert A. Neff, Natalie Welty, Timothy W. Lovenberg, Pascal Bonaventure, Alan D. Wickenden, Michael A. Letavic	2013	159
3	Identification and Biological Evaluation of 4-(3-Trifluoromethylpyridin-2-yl)piperazine-1-carboxylic Acid (5-Trifluoromethylpyridin-2-yl)amide, a High Affinity TRPV1 (VR1) Vanilloid Receptor Antagonist Journal of Medicinal Chemistry ·Devin M. Swanson, Adrienne E. Dubin, Chandra Shah, Nadia Nasser, Leon Chang, Scott L. Dax, Michele C. Jetter, J. Guy Breitenbucher, Changlu Liu, Curt Mazur, Brian Lord, Lisa Gonzales, Kenway Hoey, Michèle Rizzolio, Michael Bogenstaetter, Ellen E. Codd, Doo H. Lee, Sui‐Po Zhang, Sandra R. Chaplan, Nicholas I. Carruthers	2004	144
4	Selective Blockade of 5-Hydroxytryptamine (5-HT)7 Receptors Enhances 5-HT Transmission, Antidepressant-Like Behavior, and Rapid Eye Movement Sleep Suppression Induced by Citalopram in Rodents Journal of Pharmacology and Experimental Therapeutics ·Pascal Bonaventure, Lisa A. Kelly, Leah Aluisio, Jonathan Shelton, Brian Lord, Ruggero Galici, Kirsten L. Miller, John Atack, Timothy W. Lovenberg, Christine Dugovic	2007	139
5	Brain α7 Nicotinic Acetylcholine Receptor Assembly Requires NACHO Neuron ·Shenyan Gu, José A. Matta, Brian Lord, Anthony Harrington, Steven W. Sutton, Weston B. Davini, David S. Bredt	2016	131
6	Acute wake‐promoting actions of JNJ‐5207852, a novel, diamine‐based H₃ antagonist British Journal of Pharmacology ·Ann Barbier, Craig W. Berridge, Christine Dugovic, Aaron D. Laposky, Sandy J. Wilson, Jamin D. Boggs, Leah Aluisio, Brian Lord, Curt Mazur, Cindy M. Pudiak, Xavier Langlois, Wei Xiao, Richard L. Apodaca, Nicholas I. Carruthers, Timothy W. Lovenberg	2004	123
7	Histamine H3 receptor antagonists: From target identification to drug leads Biochemical Pharmacology ·Pascal Bonaventure, Michael A. Letavic, Christine Dugovic, Sandy Wilson, Leah Aluisio, Cindy M. Pudiak, Brian Lord, Curt Mazur, Fredrik Kamme, Seiji Nishino, Nicholas I. Carruthers, Timothy W. Lovenberg	2006	112
8	A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects Journal of Pharmacology and Experimental Therapeutics ·Pascal Bonaventure, Sujin Yun, Philip L. Johnson, Anantha Shekhar, Stephanie D. Fitz, Brock T. Shireman, Terry P. Lebold, Diane Nepomuceno, Brian Lord, Michelle Wennerholm, Jonathan Shelton, Nicholas I. Carruthers, Timothy W. Lovenberg, Christine Dugovic	2015	74
9	Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8 Journal of Pharmacology and Experimental Therapeutics ·Michael P. Maher, Nancy Wu, Surendra K. Ravula, Michael K. Ameriks, Brad M. Savall, C. Liu, Brian Lord, Ryan M. Wyatt, José A. Matta, Christine Dugovic, Sun Ae Yun, Luc Ver Donck, Thomas Steckler, Alan D. Wickenden, Nicholas I. Carruthers, Timothy W. Lovenberg	2016	74
10	Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia Journal of Pharmacology and Experimental Therapeutics ·Pascal Bonaventure, Jonathan Shelton, Sujin Yun, Diane Nepomuceno, Steven W. Sutton, Leah Aluisio, Ian Fraser, Brian Lord, James R. Shoblock, Natalie Welty, Sandra R. Chaplan, Zuleima Aguilar, Robin Halter, Anthony Ndifor, Tatiana Koudriakova, Michèle Rizzolio, Michael A. Letavic, Nicholas I. Carruthers, Timothy W. Lovenberg, Christine Dugovic	2015	71
11	Pharmacology of a Novel Central Nervous System–Penetrant P2X7 Antagonist JNJ-42253432 Journal of Pharmacology and Experimental Therapeutics ·Brian Lord, Leah Aluisio, James R. Shoblock, Robert A. Neff, Elena I. Varlinskaya, Marc Ceusters, Timothy W. Lovenberg, Nicholas I. Carruthers, Pascal Bonaventure, Michael A. Letavic, Terrence Deak, Wilhelmus Drinkenburg, Anindya Bhattacharya	2014	65
12	NACHO Mediates Nicotinic Acetylcholine Receptor Function throughout the Brain Cell Reports ·José A. Matta, Shenyan Gu, Weston B. Davini, Brian Lord, Edward R. Siuda, Anthony Harrington, David S. Bredt	2017	65
13	Neuropsychopharmacology of JNJ-55308942: evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia Neuropsychopharmacology ·Anindya Bhattacharya, Brian Lord, Jan-Sebastian Grigoleit, Yingbo He, Ian Fraser, Shannon Campbell, Natalie Taylor, Leah Aluisio, Jason C. O’Connor, Mariusz Papp, Christa C. Chrovian, Nicholas I. Carruthers, Timothy W. Lovenberg, Michael A. Letavic	2018	61
14	A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate Journal of Medicinal Chemistry ·Christa C. Chrovian, Akinola Soyode-Johnson, Alexander A. Peterson, Christine F. Gelin, Xiaohu Deng, Curt A. Dvorak, Nicholas I. Carruthers, Brian Lord, Ian Fraser, Leah Aluisio, Kevin J. Coe, Brian Scott, Tatiana Koudriakova, Freddy Schoetens, Kia Sepassi, David J. Gallacher, Anindya Bhattacharya, Michael A. Letavic	2017	60
15	Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models PLoS ONE ·Wolfgang B. Fischer, Heike Franke, Ute Krügel, Heiko Müller, Klaus Dinkel, Brian Lord, Michael A. Letavic, David C. Henshall, Tobías Engel	2016	55
16	P2X7 receptor antagonism reduces the severity of spontaneous seizures in a chronic model of temporal lobe epilepsy Neuropharmacology ·Halima Amhaoul, Idrish Ali, Marco Mola, Annemie Van Eetveldt, Krystyna Szewczyk, Stephan Missault, Kenny Bielen, Samir Kumar‐Singh, Jason C. Rech, Brian Lord, Marc Ceusters, Anindya Bhattacharya, Stefanie Dedeurwaerdere	2016	54
17	In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y2 receptor Psychopharmacology ·James R. Shoblock, Natalie Welty, Diane Nepomuceno, Brian Lord, Leah Aluisio, Ian Fraser, S. Timothy Motley, Steve W. Sutton, Kirsten L. Morton, Ruggero Galici, John Atack, Lisa Dvorak, Devin M. Swanson, Nicholas I. Carruthers, Curt A. Dvorak, Timothy W. Lovenberg, Pascal Bonaventure	2009	48
18	A novel radioligand for the ATP-gated ion channel P2X7: [3H] JNJ-54232334 European Journal of Pharmacology ·Brian Lord, Michael K. Ameriks, Qi Wang, Lawrence Fourgeaud, Maarten Vliegen, Willy Verluyten, Pieter Haspeslagh, Nicholas I. Carruthers, Timothy W. Lovenberg, Pascal Bonaventure, Michael A. Letavic, Anindya Bhattacharya	2015	45
19	JNJ-10181457, a selective non-imidazole histamine H3 receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition Neuropharmacology ·Ruggero Galici, Jamin D. Boggs, Leah Aluisio, Ian Fraser, Pascal Bonaventure, Brian Lord, Timothy W. Lovenberg	2009	44
20	Pharmacological Blockade of Serotonin 5-HT7 Receptor Reverses Working Memory Deficits in Rats by Normalizing Cortical Glutamate Neurotransmission PLoS ONE ·Pascal Bonaventure, Leah Aluisio, James R. Shoblock, Jamin D. Boggs, Ian Fraser, Brian Lord, Timothy W. Lovenberg, Ruggero Galici	2011	42

About Brian Lord

Brian Lord is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Physiology, Immunology and Cognitive Neuroscience, having authored 65 papers that have together received 2.6k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (18 papers), Mast cells and histamine (16 papers), Adenosine and Purinergic Signaling (15 papers), Neuroscience and Neuropharmacology Research (12 papers), Sleep and Wakefulness Research (10 papers), Phenothiazines and Benzothiazines Synthesis and Activities (9 papers), Olfactory and Sensory Function Studies (7 papers) and Circadian rhythm and melatonin (7 papers). The work is most often cited by research in Physiology (536 citations), Biological Psychiatry (234 citations), Endocrine and Autonomic Systems (540 citations), Sensory Systems (291 citations) and Cellular and Molecular Neuroscience (612 citations). Brian Lord has collaborated with scholars based in United States, Belgium and Netherlands. Frequent co-authors include Timothy W. Lovenberg, Nicholas I. Carruthers, Pascal Bonaventure, Leah Aluisio, Michael A. Letavic, Christine Dugovic, Ian Fraser, Anindya Bhattacharya, Jamin D. Boggs and Curt Mazur. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, ACS Medicinal Chemistry Letters, Journal of Pharmacology and Experimental Therapeutics, Journal of Medicinal Chemistry and European Journal of Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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