Brian L. West

28.6k citations

150 papers · 17.4k indexed · 11 hit papers · h-index 59

Impact in

Neurology top 0.05%
- Neuroinflammation and Neurodegeneration Mechanisms
Immunology top 0.1%
- Immune cells in cancer
- Immune Cell Function and Interaction
- Phagocytosis and Immune Regulation
- Immunotherapy and Immune Responses

Papers in

Neurology 30
- Neuroinflammation and Neurodegeneration Mechanisms 30
Immunology 38
- Immune cells in cancer 29
- Immune Response and Inflammation 13

Co-authors: John D. Baxter Kim N. Green Allison R. Najafi Monica R. P. Elmore James W. Apriletti Robert J. Fletterick Hoa Nguyen Rachel Rice
Journals: Molecular Endocrinology (11 papers)Journal of Biological Chemistry (8 papers)Cancer Research (7 papers)Molecular and Cellular Biology (5 papers)Journal of Neuroinflammation (4 papers)
Partner nations: United States Canada Germany

In The Last Decade

Brian L. West

146 papers receiving 17.1k citations

Hit Papers

11 papers align trajectories log scale

Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology 2016 · 514 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2016 Brain
2016 Nature Communications
2015 Neuro-Oncology
2014 Cancer Research
2014 Neuron
2013 Cancer Research
2012 Cancer Research
2011 Cancer Discovery
2006 Nature Genetics
1995 Nature
1983 DNA

Peers

Countries citing papers authored by Brian L. West

Since Specialization

Citations

This map shows the geographic impact of Brian L. West's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian L. West with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian L. West more than expected).

Fields of papers citing papers by Brian L. West

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian L. West. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian L. West. The network helps show where Brian L. West may publish in the future.

Co-authors

The 25 scholars most cited alongside Brian L. West, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Brian L. West Line = papers co-authored together Brian L. West links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma Antioxidants ·Korrapati V. Sathyasaikumar, Verónica Pérez de la Cruz, Benjamín Pineda, Gustavo Ignacio Vázquez Cervantes, Daniela Ramírez Ortega, David W. Donley, Paul Severson, Brian L. West, Flaviano Giorgini, Jonathan H. Fox, Robert Schwarcz	2022	19
2	Recurrent Mutations in Cyclin D3 Confer Clinical Resistance to FLT3 Inhibitors in Acute Myeloid Leukemia Clinical Cancer Research ·Catherine C. Smith, Aaron D. Viny, Evan Massi, Cyriac Kandoth, Nicholas D. Socci, Franck Rapaport, Matthieu Najm, Juan S. Medina-Martínez, Elli Papaemmanuil, Theodore C. Tarver, Henry H. Hsu, Mai H. Le, Brian L. West, Gideon Bollag, Barry S. Taylor, Ross L. Levine, Neil P. Shah	2021	11
3	Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain PLoS Biology ·Lihong Zhan, Grietje Krabbe, Fei Du, Ian Jones, Meredith C. Reichert, Maria A. Telpoukhovskaia, Lay Kodama, Chao Wang, Seo-Hyun Cho, Faten A. Sayed, Yaqiao Li, David Le, Yungui Zhou, Yin Shen, Brian L. West, Li Gan	2019	109
4	CSF1 Receptor Targeting in Prostate Cancer Reverses Macrophage-Mediated Resistance to Androgen Blockade Therapy Cancer Research ·Jemima Escamilla, Shiruyeh Schokrpur, Connie Liu, Saul J. Priceman, Diana Moughon, Ziyue Karen Jiang, Frédéric Pouliot, Clara E. Magyar, James L. Sung, Jingying Xu, Gang Deng, Brian L. West, Gideon Bollag, Yves Fradet, Louis Lacombe, Michael E. Jung, Jiaoti Huang, Lily Wu	2015	149
5	Therapeutic Peptide Vaccine-Induced CD8 T Cells Strongly Modulate Intratumoral Macrophages Required for Tumor Regression Cancer Immunology Research ·Tetje C. van der Sluis, Marjolein Sluijter, Suzanne van Duikeren, Brian L. West, Cornelis J.M. Melief, Ramon Arens, Sjoerd H. van der Burg, Thorbald van Hall	2015	70
6	Targeting cells of the myeloid lineage attenuates pain and disease progression in a prostate model of bone cancer Pain ·Michelle L. Thompson, Juan Miguel Jiménez‐Andrade, Stephane Chartier, James Tsai, Elizabeth A. Burton, Gaston Habets, Paul Lin, Brian L. West, Patrick W. Mantyh	2015	23
7	Phase 1/2a study of double immune suppression blockade by combining a CSF1R inhibitor (pexidartinib/PLX3397) with an anti PD-1 antibody (pembrolizumab) to treat advanced melanoma and other solid tumors Annals of Oncology ·Siwen Hu‐Lieskovan, Amita Patnaik, Peter D. Eisenberg, Jasgit C. Sachdev, Amy Weise, David R. Kaufman, Ireene Aromin, Brian L. West, Shiyu Tong, Antoni Ribas	2015	4
8	CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models Cancer Research ·Yu Zhu, Brett L. Knolhoff, Melissa A. Meyer, Timothy M. Nywening, Brian L. West, Jingqin Luo, Andrea Wang‐Gillam, S. Peter Goedegebuure, David C. Linehan, David G. DeNardo Hit paper breakdown →	2014	974
9	Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy Cancer Research ·Stephen Mok, Richard C. Koya, Christopher Tsui, Jingying Xu, Lídia Robert, Lily Wu, Thomas G. Graeber, Brian L. West, Gideon Bollag, Antoni Ribas	2013	252
10	CSF1R Signaling Blockade Stanches Tumor-Infiltrating Myeloid Cells and Improves the Efficacy of Radiotherapy in Prostate Cancer Cancer Research ·Jingying Xu, Jemima Escamilla, Stephen Mok, John David, Saul J. Priceman, Brian L. West, Gideon Bollag, William H. McBride, Lily Wu Hit paper breakdown →	2013	467
11	Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses Cancer Research ·Jonathan B. Mitchem, Donal J. Brennan, Brett L. Knolhoff, Brian A. Belt, Yu Zhu, Dominic E. Sanford, Larisa Belaygorod, Danielle Carpenter, Lynne Collins, David Piwnica‐Worms, Stephen M. Hewitt, Girish Mallya Udupi, William M. Gallagher, Craig D. Wegner, Brian L. West, Andrea Wang‐Gillam, Peter S. Goedegebuure, David C. Linehan, David G. DeNardo Hit paper breakdown →	2012	759
12	Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy Cancer Discovery ·David G. DeNardo, Donal J. Brennan, Elton Rexhepaj, Brian Ruffell, Stephen L. Shiao, Stephen F. Madden, William M. Gallagher, Nikhil Wadhwani, Scott D. Keil, Sharfaa A. Junaid, Hope S. Rugo, E. Shelley Hwang, Karin Jirström, Brian L. West, Lisa M. Coussens Hit paper breakdown →	2011	1320
13	Two novel STRA6 mutations in a patient with anophthalmia and diaphragmatic eventration American Journal of Medical Genetics Part A ·Brian L. West, Kevin E. Bove, Anne Slavotinek	2009	20
14	A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases Molecular Cell ·Kam Y. J. Zhang, G.L. Card, Yoshihisa Suzuki, David Artis, Daniel W. Fong, S. Gillette, Davin Hsieh, Joshua Neiman, Brian L. West, Chao Zhang, Michael V. Milburn, Sung‐Hou Kim, Joseph Schlessinger, Gideon Bollag	2004	220
15	An immunogold investigation of the distribution of calmodulin in the apex of cochlear hair cells Hearing Research ·David N. Furness, A. Karkanevatos, Brian L. West, Carole M. Hackney	2002	26
16	The Nuclear Receptor Corepressor (N-CoR) Contains Three Isoleucine Motifs (I/LXXII) That Serve as Receptor Interaction Domains (IDs) Molecular Endocrinology ·Paul Webb, Carol M. Anderson, Cathleen D. Valentine, Phuong Nguyen, Adhirai Marimuthu, Brian L. West, John D. Baxter, Peter J. Kushner	2000	121
17	X-ray crystallographic and functional studies of thyroid hormone receptor The Journal of Steroid Biochemistry and Molecular Biology ·Ralff C.J. Ribeiro, James W. Apriletti, Richard Wagner, Weijun Feng, Peter J. Kushner, Stefan Nilsson, Thomas S. Scanlan, Brian L. West, Robert J. Fletterick, John D. Baxter	1998	59
18	Mutations in the Conserved C-Terminal Sequence in Thyroid Hormone Receptor Dissociate Hormone-Dependent Activation from Interference with AP-1 Activity Molecular and Cellular Biology ·Fahri Saatcioglu, Gabriela N. Lopez, Brian L. West, Ebrahim Zandi, Weijun Feng, Haiping Lu, Ali Esmaili, James W. Apriletti, Peter J. Kushner, John D. Baxter, Michael Karin	1997	39
19	Expression of the Rat α1 Thyroid Hormone Receptor Ligand Binding Domain in Escherichia coli and the Use of a Ligand-Induced Conformation Change as a Method for Its Purification to Homogeneity Protein Expression and Purification ·James W. Apriletti, John D. Baxter, K.‐H. William Lau, Brian L. West	1995	35
20	A Method for Isolation of Intact, Translationally Active Ribonucleic Acid DNA ·Guy Cathala, Jean François Savouret, Bernardita Méndez, Brian L. West, Michael Karin, Joseph Martial, John D. Baxter Hit paper breakdown →	1983	1396

About Brian L. West

Brian L. West is a scholar working on Neurology, Immunology, Endocrinology, Diabetes and Metabolism, Developmental Neuroscience and Biological Psychiatry, having authored 150 papers that have together received 17.4k indexed citations. Recurring topics across this work include Neuroinflammation and Neurodegeneration Mechanisms (30 papers), Immune cells in cancer (29 papers), Estrogen and related hormone effects (24 papers), Growth Hormone and Insulin-like Growth Factors (17 papers), Retinoids in leukemia and cellular processes (14 papers), Immune Response and Inflammation (13 papers), Cancer Immunotherapy and Biomarkers (9 papers) and Thyroid Disorders and Treatments (9 papers). The work is most often cited by research in Neurology (4.4k citations), Immunology (6.6k citations), Biological Psychiatry (585 citations), Developmental Neuroscience (895 citations) and Oncology (4.1k citations). Brian L. West has collaborated with scholars based in United States, Canada and Germany. Frequent co-authors include John D. Baxter, Kim N. Green, Allison R. Najafi, Monica R. P. Elmore, James W. Apriletti, Robert J. Fletterick, Hoa Nguyen, Rachel Rice, Elizabeth E. Spangenberg and David G. DeNardo. Their work appears in journals such as Molecular Endocrinology, Journal of Biological Chemistry, Cancer Research, Molecular and Cellular Biology and Journal of Neuroinflammation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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