Brett L. Knolhoff

6.4k total citations · 5 hit papers
27 papers, 4.6k citations indexed

About

Brett L. Knolhoff is a scholar working on Immunology, Oncology and Surgery. According to data from OpenAlex, Brett L. Knolhoff has authored 27 papers receiving a total of 4.6k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Immunology, 14 papers in Oncology and 6 papers in Surgery. Recurrent topics in Brett L. Knolhoff's work include Immune cells in cancer (13 papers), Cancer Immunotherapy and Biomarkers (10 papers) and Pancreatic and Hepatic Oncology Research (8 papers). Brett L. Knolhoff is often cited by papers focused on Immune cells in cancer (13 papers), Cancer Immunotherapy and Biomarkers (10 papers) and Pancreatic and Hepatic Oncology Research (8 papers). Brett L. Knolhoff collaborates with scholars based in United States, Australia and Ireland. Brett L. Knolhoff's co-authors include David G. DeNardo, Yu Zhu, Andrea Wang‐Gillam, Melissa A. Meyer, Timothy M. Nywening, Jingqin Luo, David C. Linehan, Brian L. West, William G. Hawkins and John M. Herndon and has published in prestigious journals such as Nature Medicine, Nature Communications and Immunity.

In The Last Decade

Brett L. Knolhoff

27 papers receiving 4.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models

2014 974 citations Yu Zhu, Brett L. Knolhoff et al. Cancer Research profile →
Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

2012 759 citations Jonathan B. Mitchem, Donal J. Brennan et al. Cancer Research profile →
Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

2016 754 citations Hong Jiang, Samarth Hegde et al. Nature Medicine profile →
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression

2017 585 citations Yu Zhu, John M. Herndon et al. Immunity profile →
Senescence Defines a Distinct Subset of Myofibroblasts That Orchestrates Immunosuppression in Pancreatic Cancer

2024 56 citations Jad I. Belle, John Baer et al. Cancer Discovery profile →

Peers

Countries citing papers authored by Brett L. Knolhoff

Since Specialization

Citations

This map shows the geographic impact of Brett L. Knolhoff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brett L. Knolhoff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brett L. Knolhoff more than expected).

Fields of papers citing papers by Brett L. Knolhoff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brett L. Knolhoff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brett L. Knolhoff. The network helps show where Brett L. Knolhoff may publish in the future.

Co-authorship network of co-authors of Brett L. Knolhoff

This figure shows the co-authorship network connecting the top 25 collaborators of Brett L. Knolhoff. A scholar is included among the top collaborators of Brett L. Knolhoff based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brett L. Knolhoff. Brett L. Knolhoff is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Senescence Defines a Distinct Subset of Myofibroblasts That Orchestrates Immunosuppression in Pancreatic Cancer breakdown → 2024 ·Cancer Discovery ·Jad I. Belle, (unknown), John Baer, Xiuting Liu, Varintra E. Lander, Jiayu Ye, (unknown), Brett L. Knolhoff, Faiz Ahmad, Liang‐I Kang, (unknown), Ryan C. Fields, Li Ding, Hyun Kim, Paolo P. Provenzano, Sheila A. Stewart, David G. DeNardo	56
2	Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non–small cell lung cancer 2023 ·Science Translational Medicine ·Brett H. Herzog, John Baer, Nicholas Borcherding, Natalie L. Kingston, Jad I. Belle, Brett L. Knolhoff, Graham D. Hogg, Faiz Ahmad, Liang‐I Kang, (unknown), Chieh‐Yu Lin, Ramaswamy Govindan, David G. DeNardo	44
3	Systemic Alterations in Type-2 Conventional Dendritic Cells Lead to Impaired Tumor Immunity in Pancreatic Cancer 2023 ·Cancer Immunology Research ·(unknown), John Baer, (unknown), (unknown), Brett L. Knolhoff, Graham D. Hogg, Natalie L. Kingston, Liang‐I Kang, Varintra E. Lander, Jingqin Luo, (unknown), Mark A. Watson, Rebecca Aft, Ryan C. Fields, William G. Hawkins, David G. DeNardo	13
4	Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity 2023 ·Cancer Cell ·Xiuting Liu, Graham D. Hogg, Chong Zuo, Nicholas Borcherding, John Baer, Varintra E. Lander, Liang‐I Kang, Brett L. Knolhoff, Faiz Ahmad, Robin Osterhout, Anna Galkin, Jean‐Marie Bruey, Laura Carter, Cedric Mpoy, Kiran Vij, Ryan C. Fields, Julie K. Schwarz, Haeseong Park, Vineet Gupta, David G. DeNardo	53
5	Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC 2023 ·Nature Immunology ·John Baer, Chong Zuo, Liang‐I Kang, (unknown), Nicholas Borcherding, Brett L. Knolhoff, (unknown), Yu Zhu, Liping Yang, (unknown), Mark A. Lewis, Nan Zhang, Ki-Wook Kim, Ryan C. Fields, Wayne M. Yokoyama, Jason C. Mills, Li Ding, Gwendalyn J. Randolph, David G. DeNardo	47
6	IRAK4 Signaling Drives Resistance to Checkpoint Immunotherapy in Pancreatic Ductal Adenocarcinoma 2022 ·Gastroenterology ·(unknown), Daoxiang Zhang, (unknown), Varintra E. Lander, Xiuting Liu, Liang‐I Kang, (unknown), Brett L. Knolhoff, Lin Li, Patrick Grierson, Marianna B. Ruzinova, David G. DeNardo, Kian‐Huat Lim	33
7	Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade 2022 ·Cancer Discovery ·Varintra E. Lander, Jad I. Belle, Natalie L. Kingston, John M. Herndon, Graham D. Hogg, Xiuting Liu, Liang‐I Kang, Brett L. Knolhoff, (unknown), John Baer, Chong Zuo, Nicholas Borcherding, (unknown), Cedric Mpoy, Jalen Scott, Michael C. Zahner, Buck E. Rogers, Julie K. Schwarz, Hyun Kim, David G. DeNardo	66
8	Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer 2020 ·Cancer Cell ·Samarth Hegde, (unknown), Brett H. Herzog, Chong Zuo, Marcus Breden, Brett L. Knolhoff, Graham D. Hogg, Jack Pengfei Tang, John Baer, Cedric Mpoy, Kyung Bae Lee, Katherine A. Alexander, Buck E. Rogers, Kenneth M. Murphy, William G. Hawkins, Ryan C. Fields, Carl J. DeSelm, Julie K. Schwarz, David G. DeNardo	295
9	Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion 2019 ·Gut ·Hong Jiang, Xiuting Liu, Brett L. Knolhoff, Samarth Hegde, Kyung Bae Lee, Hongmei Jiang, Ryan C. Fields, Jonathan A. Pachter, Kian‐Huat Lim, David G. DeNardo	101
10	CD11b hyperactivation improves response to immunotherapy in pancreatic cancer 2018 ·HPB ·Roheena Z. Panni, John M. Herndon, Brett L. Knolhoff, Graham D. Hogg, Vivek Gupta, Ryan C. Fields, (unknown), David G. DeNardo	1
11	SNAIL1 action in tumor cells influences macrophage polarization and metastasis in breast cancer through altered GM-CSF secretion 2018 ·Oncogenesis ·Audrey Brenot, Brett L. Knolhoff, David G. DeNardo, Gregory D. Longmore	44
12	Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance 2018 ·Nature Communications ·Melissa A. Meyer, John Baer, Brett L. Knolhoff, Timothy M. Nywening, Roheena Z. Panni, Xinming Su, Katherine N. Weilbaecher, William G. Hawkins, X. Cynthia, Ryan C. Fields, David C. Linehan, Grant A. Challen, Roberta Faccio, Rebecca Aft, David G. DeNardo	170
13	Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression breakdown → 2017 ·Immunity ·Yu Zhu, John M. Herndon, Dorothy K. Sojka, Ki-Wook Kim, Brett L. Knolhoff, Chong Zuo, Darren R. Cullinan, Jingqin Luo, (unknown), Kory J. Lavine, Wayne M. Yokoyama, William G. Hawkins, Ryan C. Fields, Gwendalyn J. Randolph, David G. DeNardo	585
14	Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma 2016 ·Clinical Cancer Research ·Daoxiang Zhang, Lin Li, Hongmei Jiang, Brett L. Knolhoff, A. Craig Lockhart, Andrea Wang‐Gillam, David G. DeNardo, Marianna B. Ruzinova, Kian‐Huat Lim	60
15	Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis 2016 ·Nature Communications ·Megan K. Ruhland, Andrew J. Loza, Aude-Hélène Capietto, Xianmin Luo, Brett L. Knolhoff, Kevin C. Flanagan, Brian A. Belt, Elise Alspach, K. Leahy, Jingqin Luo, András Schaffer, John R. Edwards, Gregory D. Longmore, Roberta Faccio, David G. DeNardo, Sheila A. Stewart	350
16	Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy breakdown → 2016 ·Nature Medicine ·Hong Jiang, Samarth Hegde, Brett L. Knolhoff, Yu Zhu, John M. Herndon, Melissa A. Meyer, Timothy M. Nywening, William G. Hawkins, Irina M. Shapiro, David T. Weaver, Jonathan A. Pachter, Andrea Wang‐Gillam, David G. DeNardo	754
17	CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models breakdown → 2014 ·Cancer Research ·Yu Zhu, Brett L. Knolhoff, Melissa A. Meyer, Timothy M. Nywening, Brian L. West, Jingqin Luo, Andrea Wang‐Gillam, S. Peter Goedegebuure, David C. Linehan, David G. DeNardo	974
18	BH3-only proteins contribute to steatotic liver ischemia–reperfusion injury 2014 ·Journal of Surgical Research ·Bernard J. DuBray, Kendra D. Conzen, Gundumi A. Upadhya, (unknown), Jianluo Jia, Brett L. Knolhoff, (unknown), William C. Chapman, Christopher D. Anderson	5
19	Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses breakdown → 2012 ·Cancer Research ·Jonathan B. Mitchem, Donal J. Brennan, Brett L. Knolhoff, Brian A. Belt, Yu Zhu, Dominic E. Sanford, Larisa Belaygorod, Danielle Carpenter, Lynne Collins, David Piwnica‐Worms, Stephen M. Hewitt, Girish Mallya Udupi, William M. Gallagher, Craig D. Wegner, Brian L. West, Andrea Wang‐Gillam, Peter S. Goedegebuure, David C. Linehan, David G. DeNardo	759
20	Novel in vitro model for studying hepatic ischemia-reperfusion injury using liver cubes 2012 ·Surgery ·Bernard J. DuBray, Kendra D. Conzen, Gundumi A. Upadhya, (unknown), Jianluo Jia, Brett L. Knolhoff, David Alpers, (unknown), William C. Chapman, Christopher D. Anderson	2

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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