David Le

2.2k total citations · 1 hit paper
11 papers, 770 citations indexed

About

David Le is a scholar working on Neurology, Physiology and Immunology. According to data from OpenAlex, David Le has authored 11 papers receiving a total of 770 indexed citations (citations by other indexed papers that have themselves been cited), including 7 papers in Neurology, 4 papers in Physiology and 3 papers in Immunology. Recurrent topics in David Le's work include Neuroinflammation and Neurodegeneration Mechanisms (7 papers), Alzheimer's disease research and treatments (4 papers) and Neurological Disease Mechanisms and Treatments (3 papers). David Le is often cited by papers focused on Neuroinflammation and Neurodegeneration Mechanisms (7 papers), Alzheimer's disease research and treatments (4 papers) and Neurological Disease Mechanisms and Treatments (3 papers). David Le collaborates with scholars based in United States, Australia and Paraguay. David Le's co-authors include Li Gan, Yaqiao Li, Yungui Zhou, Lihong Zhan, Lay Kodama, Faten A. Sayed, Maria A. Telpoukhovskaia, Sakura Minami, Birgit Schilling and Tara E. Tracy and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Clinical Investigation and Nature Communications.

In The Last Decade

David Le

11 papers receiving 765 citations

Hit Papers

Microglial NF-κB drives tau spreading and toxicity in a m... 2022 2026 2023 2024 2022 50 100 150
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
    2022 186 citations Li Fan, Rabia R. Khawaja et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
David Le United States 10 456 360 197 176 132 11 770
Fading Chen United States 7 361 0.8× 348 1.0× 278 1.4× 105 0.6× 131 1.0× 10 796
Jennifer Rodriguez-Rivera United States 8 455 1.0× 490 1.4× 376 1.9× 133 0.8× 226 1.7× 8 1.0k
Marcel Maier United States 15 490 1.1× 561 1.6× 267 1.4× 136 0.8× 170 1.3× 19 976
Angelos Skodras Germany 13 550 1.2× 327 0.9× 253 1.3× 246 1.4× 143 1.1× 18 916
Lihong Zhan United States 15 552 1.2× 295 0.8× 338 1.7× 240 1.4× 136 1.0× 15 1.1k
Michael R. Strickland United States 12 324 0.7× 304 0.8× 225 1.1× 127 0.7× 85 0.6× 16 713
Xianyuan Xiang Germany 10 588 1.3× 286 0.8× 160 0.8× 355 2.0× 76 0.6× 16 822
Michael Hernandez United States 9 528 1.2× 251 0.7× 183 0.9× 256 1.5× 112 0.8× 12 785
Faten A. Sayed United States 8 582 1.3× 331 0.9× 168 0.9× 240 1.4× 104 0.8× 9 866
John A. Tzaferis United States 5 577 1.3× 543 1.5× 184 0.9× 255 1.4× 144 1.1× 5 917

Countries citing papers authored by David Le

Since Specialization
Citations

This map shows the geographic impact of David Le's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Le with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Le more than expected).

Fields of papers citing papers by David Le

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Le. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Le. The network helps show where David Le may publish in the future.

Co-authorship network of co-authors of David Le

This figure shows the co-authorship network connecting the top 25 collaborators of David Le. A scholar is included among the top collaborators of David Le based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Le. David Le is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

11 of 11 papers shown
1.
Kauwe, Grant, Lei Yao, Ivy Tsz-Lo Wong, et al.. (2024). KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss. Journal of Clinical Investigation. 134(3). 12 indexed citations
2.
Fan, Li, Rabia R. Khawaja, Lihong Zhan, et al.. (2022). Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy. Nature Communications. 13(1). 1969–1969. 186 indexed citations breakdown →
3.
Rege, Sanket, David Le, Rebecca D. Ray, et al.. (2022). Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice. Brain and Behavior. 12(9). e2736–e2736. 6 indexed citations
4.
Telpoukhovskaia, Maria A., Kai Liu, Faten A. Sayed, et al.. (2020). Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia. Scientific Reports. 10(1). 13688–13688. 17 indexed citations
5.
Zhan, Lihong, Grietje Krabbe, Fei Du, et al.. (2019). Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain. PLoS Biology. 17(2). e3000134–e3000134. 109 indexed citations
6.
Kodama, Lay, Elmer Guzman, Jon Iker Etchegaray, et al.. (2019). Microglial microRNAs mediate sex-specific responses to tau pathology. Nature Neuroscience. 23(2). 167–171. 79 indexed citations
7.
Sayed, Faten A., Maria A. Telpoukhovskaia, Lay Kodama, et al.. (2018). Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy. Proceedings of the National Academy of Sciences. 115(40). 10172–10177. 126 indexed citations
8.
Tracy, Tara E., Peter Sohn, Sakura Minami, et al.. (2016). Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss. Neuron. 90(2). 245–260. 200 indexed citations
9.
Minami, Sakura, David Le, Grietje Krabbe, et al.. (2015). Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists. Biochemical Pharmacology. 97(4). 454–462. 13 indexed citations
10.
11.
Le, David, et al.. (2005). Differential effects of hyperosmotic challenge on interleukin-1-activated pathways in bovine articular cartilage. Archives of Biochemistry and Biophysics. 445(1). 1–8. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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