Jay L. Zweíer

52.2k total citations · 17 hit papers
554 papers, 42.5k citations indexed

About

Jay L. Zweíer is a scholar working on Biophysics, Physiology and Molecular Biology. According to data from OpenAlex, Jay L. Zweíer has authored 554 papers receiving a total of 42.5k indexed citations (citations by other indexed papers that have themselves been cited), including 286 papers in Biophysics, 179 papers in Physiology and 145 papers in Molecular Biology. Recurrent topics in Jay L. Zweíer's work include Electron Spin Resonance Studies (286 papers), Nitric Oxide and Endothelin Effects (164 papers) and Lanthanide and Transition Metal Complexes (90 papers). Jay L. Zweíer is often cited by papers focused on Electron Spin Resonance Studies (286 papers), Nitric Oxide and Endothelin Effects (164 papers) and Lanthanide and Transition Metal Complexes (90 papers). Jay L. Zweíer collaborates with scholars based in United States, China and Japan. Jay L. Zweíer's co-authors include Periannan Kuppusamy, Yong Xia, Alexandre Samouilov, Penghai Wang, Yeong-Renn Chen, John T. Flaherty, Myron L. Weisfeldt, Frederick A. Villamena, Kenneth W. Kinzler and Kornélia Polyák and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Jay L. Zweíer

547 papers receiving 41.6k citations

Hit Papers

A model for p53-induced apoptosis 1978 2026 1994 2010 1997 1997 2000 1987 1995 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A model for p53-induced apoptosis
    1997 2.1k citations Jay L. Zweíer et al. profile →
  2. Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts
    1997 1.3k citations Jay L. Zweíer et al. profile →
  3. Reactive Oxygen Species (Ros-Induced) Ros Release
    2000 1.2k citations Jay L. Zweíer et al. profile →
  4. Direct measurement of free radical generation following reperfusion of ischemic myocardium.
    1987 977 citations Jay L. Zweíer et al. profile →
  5. Enzyme-independent formation of nitric oxide in biological tissues
    1995 630 citations Jay L. Zweíer, Alexandre Samouilov et al. profile →
  6. Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels.
    2002 625 citations Periannan Kuppusamy, Arturo J. Cardounel et al. PubMed profile →
  7. Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury.
    1996 618 citations Jay L. Zweíer et al. profile →
  8. Superoxide Generation from Endothelial Nitric-oxide Synthase
    1998 578 citations Jay L. Zweíer et al. Journal of Biological Chemistry profile →
  9. Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages
    1997 570 citations Jay L. Zweíer et al. profile →
  10. The role of oxidants and free radicals in reperfusion injury
    2006 568 citations Jay L. Zweíer et al. profile →
  11. The natural polyamine spermine functions directly as a free radical scavenger
    1998 563 citations Periannan Kuppusamy, Jay L. Zweíer et al. profile →
  12. MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2
    2009 552 citations Craig Hemann, Jay L. Zweíer et al. profile →
  13. Measurement of superoxide-derived free radicals in the reperfused heart. Evidence for a free radical mechanism of reperfusion injury.
    1988 542 citations Jay L. Zweíer Journal of Biological Chemistry profile →
  14. Measurement of endothelial cell free radical generation: evidence for a central mechanism of free radical injury in postischemic tissues.
    1988 514 citations Jay L. Zweíer, Periannan Kuppusamy et al. profile →
  15. Cardiac Mitochondria and Reactive Oxygen Species Generation
    2014 490 citations Jay L. Zweíer et al. profile →
  16. Stoichiometric and site characteristics of the binding of iron to human transferrin.
    1978 486 citations Jay L. Zweíer et al. Journal of Biological Chemistry profile →
  17. Hearts From Rodents Exposed to Intermittent Hypoxia or Erythropoietin Are Protected Against Ischemia-Reperfusion Injury
    2003 468 citations Jay L. Zweíer et al. Circulation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jay L. Zweíer United States 98 15.3k 12.0k 7.9k 6.1k 5.6k 554 42.5k
Balaraman Kalyanaraman United States 89 13.4k 0.9× 7.3k 0.6× 2.7k 0.3× 1.6k 0.3× 2.7k 0.5× 349 30.8k
Joseph S. Beckman United States 80 13.1k 0.9× 20.0k 1.7× 2.9k 0.4× 3.7k 0.6× 3.0k 0.5× 184 42.7k
Michael J. Davies Australia 95 14.3k 0.9× 6.7k 0.6× 2.2k 0.3× 1.8k 0.3× 2.2k 0.4× 677 40.9k
Irwin Fridovich United States 116 33.8k 2.2× 9.7k 0.8× 2.7k 0.3× 3.5k 0.6× 1.5k 0.3× 420 88.8k
David A. Wink United States 101 10.1k 0.7× 14.2k 1.2× 2.5k 0.3× 1.8k 0.3× 2.4k 0.4× 355 35.8k
Ronald P. Mason United States 97 12.4k 0.8× 5.6k 0.5× 4.7k 0.6× 2.0k 0.3× 1.6k 0.3× 659 33.3k
Helmut Sies Germany 132 30.1k 2.0× 10.6k 0.9× 1.6k 0.2× 4.0k 0.7× 1.7k 0.3× 657 81.4k
Bruce Α. Freeman United States 100 15.9k 1.0× 19.4k 1.6× 2.7k 0.3× 3.9k 0.6× 4.9k 0.9× 297 46.5k
Rafael Radí Uruguay 97 14.9k 1.0× 14.3k 1.2× 2.8k 0.4× 2.1k 0.3× 1.6k 0.3× 339 36.9k
Michael P. Murphy United Kingdom 121 33.6k 2.2× 12.0k 1.0× 1.3k 0.2× 3.7k 0.6× 2.3k 0.4× 535 56.2k

Countries citing papers authored by Jay L. Zweíer

Since Specialization
Citations

This map shows the geographic impact of Jay L. Zweíer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jay L. Zweíer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jay L. Zweíer more than expected).

Fields of papers citing papers by Jay L. Zweíer

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jay L. Zweíer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jay L. Zweíer. The network helps show where Jay L. Zweíer may publish in the future.

Co-authorship network of co-authors of Jay L. Zweíer

This figure shows the co-authorship network connecting the top 25 collaborators of Jay L. Zweíer. A scholar is included among the top collaborators of Jay L. Zweíer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jay L. Zweíer. Jay L. Zweíer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Zweíer, Jay L., et al.. (2024). Nicotine inhalation and metabolism triggers AOX-mediated superoxide generation with oxidative lung injury. Journal of Biological Chemistry. 300(9). 107626–107626. 2 indexed citations
2.
Khaleel, Sahar A., et al.. (2024). Electronic cigarette vape decreases nitric oxide bioavailability in vascular smooth muscle cells via increased cytoglobin-mediated metabolism. Free Radical Biology and Medicine. 228. 339–349. 1 indexed citations
3.
Ghatak, Subhadip, Craig Hemann, James Boslett, et al.. (2023). Bacterial Pyocyanin Inducible Keratin 6A Accelerates Closure of Epithelial Defect under Conditions of Mitochondrial Dysfunction. Journal of Investigative Dermatology. 143(10). 2052–2064.e5. 4 indexed citations
4.
Headley, Colwyn A., Yongbin Han, Jay L. Zweíer, et al.. (2019). Membrane-specific spin trap, 5-dodecylcarbamoyl-5-N-dodecylacetamide-1-pyroline-N-oxide (diC12PO): theoretical, bioorthogonal fluorescence imaging and EPR studies. Organic & Biomolecular Chemistry. 17(33). 7694–7705. 5 indexed citations
5.
Tan, Xiaoli, Yuguang Song, Antal Rockenbauer, et al.. (2017). Thiol-Dependent Reduction of the Triester and Triamide Derivatives of Finland Trityl Radical Triggers O2-Dependent Superoxide Production. Chemical Research in Toxicology. 30(9). 1664–1672. 16 indexed citations
6.
7.
Lee, Daniel, et al.. (2011). Effect of Hyponatremia in Isolated Rat Hearts. The FASEB Journal. 25. 1 indexed citations
8.
Abdelghany, Tamer M., et al.. (2011). Chronic Cigarette Smoke Exposure Impairs Vascular Endothelial Function With Reactive Oxygen Species Formation and Alterations in NO Synthase. The FASEB Journal. 25. 1 indexed citations
9.
Talukder, M.A. Hassan, et al.. (2010). eNOS is required for acute in vivo ischemic preconditioning of the heart: effects of ischemic duration and sex. American Journal of Physiology-Heart and Circulatory Physiology. 299(2). H437–H445. 37 indexed citations
10.
Druhan, Lawrence J., Xiaoping Liu, & Jay L. Zweíer. (2010). Abstract 21538: Tetrahydrobiopterin Enhances Hydrogen Peroxide Production by Nitric Oxide Synthase While Suppressing Superoxide Generation: Implications for Cardiovascular Disease. Circulation. 1 indexed citations
11.
Nishijima, Yoshinori, Arun Sridhar, Ingrid M. Bonilla, et al.. (2010). Abstract 17079: Tetrahydrobiopterin (NOS Cofactor) Treatment Improves Atrial Electrophysiology in Chronic Heart Failure.. Circulation. 122. 1 indexed citations
12.
Dhimitruka, Ilirian, et al.. (2010). Synthesis, structure, and EPR characterization of deuterated derivatives of Finland trityl radical. Bioorganic & Medicinal Chemistry Letters. 20(13). 3946–3949. 37 indexed citations
13.
Elford, Howard L., Arturo J. Cardounel, Jay L. Zweíer, et al.. (2006). Didox, a unique ribonucleotide reductase inhibitor and free radical scavenger, can protect against doxorubicin caused cardiotoxicity with enhanced antitumor activity. Cancer Research. 66. 502–502. 2 indexed citations
14.
Kutala, Vijay Kumar, Periannan Kuppusamy, J. Scott Ferguson, et al.. (2004). Pulmonary Surfactant Protein A Inhibits Macrophage Reactive Oxygen Intermediate Production in Response to Stimuli by Reducing NADPH Oxidase Activity. The Journal of Immunology. 172(11). 6866–6874. 57 indexed citations
15.
16.
Kuppusamy, Periannan, Mobae Afeworki, Ravi Shankar, et al.. (1998). In vivo electron paramagnetic resonance imaging of tumor heterogeneity and oxygenation in a murine model.. PubMed. 58(7). 1562–8. 138 indexed citations
17.
Sanders, Stephen P., et al.. (1995). Spontaneous Oxygen Radical Production at Sites of Antigen Challenge in Allergic Subjects. American Journal of Respiratory and Critical Care Medicine. 151(6). 1725–1733. 101 indexed citations
18.
Zweíer, Jay L. & Periannan Kuppusamy. (1994). EPR spectroscopy of free radicals in the perfused heart. 18(1). 3 indexed citations
19.
Sanders, Scherer P., Stephen J. Harrison, Periannan Kuppusamy, J. T. Sylvester, & Jay L. Zweíer. (1994). A comparative study of EPR spin trapping and cytochrome c reduction techniques for the measurement of superoxide anions. Free Radical Biology and Medicine. 16(6). 753–761. 46 indexed citations
20.
Sanders, Scherer P., Jay L. Zweíer, Periannan Kuppusamy, et al.. (1993). Hyperoxic sheep pulmonary microvascular endothelial cells generate free radicals via mitochondrial electron transport.. Journal of Clinical Investigation. 91(1). 46–52. 96 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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