Tom H. M. Ottenhoff

37.6k citations

471 papers · 25.8k indexed · 2 hit papers · h-index 86

Impact in

Infectious Diseases top 0.01%
- Tuberculosis Research and Epidemiology
Immunology top 0.05%
- Immune Cell Function and Interaction
- Immunodeficiency and Autoimmune Disorders
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Immune Response and Inflammation

Papers in

Infectious Diseases 316
- Tuberculosis Research and Epidemiology 271
- Leprosy Research and Treatment 55
Immunology 237
- Immune Cell Function and Interaction 77
- Immunodeficiency and Autoimmune Disorders 74
- T-cell and B-cell Immunology 62
- Immunotherapy and Immune Responses 46

Co-authors: Simone A. Joosten Krista E. van Meijgaarden Annemieke Geluk Kees L. M. C. Franken Jaap T. van Dissel Tjitske de Boer Frank A. W. Verreck Stefan H. E. Kaufmann
Journals: Frontiers in Immunology (35 papers)The Journal of Immunology (27 papers)PLoS ONE (26 papers)European Journal of Immunology (23 papers)Infection and Immunity (18 papers)
Partner nations: Netherlands United Kingdom United States

In The Last Decade

Tom H. M. Ottenhoff

464 papers receiving 25.3k citations

Hit Papers

align trajectories log scale

Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria 2004 · 796 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2004 Proceedings of the National Academy of Sciences
1998 Science

Peers

Countries citing papers authored by Tom H. M. Ottenhoff

Since Specialization

Citations

This map shows the geographic impact of Tom H. M. Ottenhoff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tom H. M. Ottenhoff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tom H. M. Ottenhoff more than expected).

Fields of papers citing papers by Tom H. M. Ottenhoff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tom H. M. Ottenhoff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tom H. M. Ottenhoff. The network helps show where Tom H. M. Ottenhoff may publish in the future.

Co-authors

The 25 scholars most cited alongside Tom H. M. Ottenhoff, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tom H. M. Ottenhoff Line = papers co-authored together Tom H. M. Ottenhoff links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Sera contributing to mycobacterial growth restriction in vitro display enhanced Fc-mediated phagocytosis iScience ·Krista E. van Meijgaarden, Patricia S. Grace, Wenjun Wang, Delia Goletti, Fabrizio Palmieri, Manfred Wuhrer, Tom H. M. Ottenhoff, Simone A. Joosten	2025	0
2	Whole blood RNA signatures in tuberculosis patients receiving H56:IC31 vaccine as adjunctive therapy Frontiers in Immunology ·Noelia Alonso‐Rodríguez, Renata Ramos Pinheiro, Suzanne van Veen, Synne Jenum, Kristian Tonby, Βασιλική Μόσχου, Wen Zhou, Rasmus Mortensen, Tom H. M. Ottenhoff, Anne Ma Dyrhol‐Riise	2024	1
3	Mtb-Specific HLA-E-Restricted T Cells Are Induced during Mtb Infection but Not after BCG Administration in Non-Human Primates and Humans Vaccines ·محمّدحسین رضایی مقدّم, B. A. Askew, Iman Satti, Andrew White, Karin Dijkman, Jianhua Lin, Krista E. van Meijgaarden, Kees L. M. C. Franken, Julia L. Marshall, Tom H. M. Ottenhoff, Thomas J. Scriba, Helen McShane, Sally Sharpe, Frank A. W. Verreck, Simone A. Joosten	2024	2
4	The Human Pathogen Mycobacterium tuberculosis and the Fish Pathogen Mycobacterium marinum Trigger a Core Set of Late Innate Immune Response Genes in Zebrafish Larvae Biology ·Ron P. Dirks, Anita Ordas, Susanne Jong-Raadsen, Sebastiaan A. Brittijn, Mariëlle C. Haks, Christiaan V. Henkel, Katarína Oravcová, Péter Rácz, KANACHIRO KASHIWAGI, Małgorzata Wiweger, Stephen H. Gillespie, Annemarie H. Meijer, Tom H. M. Ottenhoff, Hans J. Jansen, Herman P. Spaink	2024	3
5	Intrinsic immunogenicity of liposomes for tuberculosis vaccines: Effect of cationic lipid and cholesterol European Journal of Pharmaceutical Sciences ·Teresa Wodarczyk, Hwa-Lim Lee, Krista E. van Meijgaarden, Wim Jiskoot, Joke A. Bouwstra, Mariëlle C. Haks, Annemieke Geluk, Tom H. M. Ottenhoff	2024	9
6	Cationic pH-sensitive liposome-based subunit tuberculosis vaccine induces protection in mice challenged with Mycobacterium tuberculosis European Journal of Pharmaceutics and Biopharmaceutics ·Teresa Wodarczyk, Susan J. F. van den Eeden, Krista E. van Meijgaarden, Kees L. M. C. Franken, Suzanne van Veen, Annemieke Geluk, Joke A. Bouwstra, Tom H. M. Ottenhoff	2024	5
7	Cationic pH-sensitive liposomes as tuberculosis subunit vaccine delivery systems: Effect of liposome composition on cellular innate immune responses International Immunopharmacology ·Teresa Wodarczyk, Krista E. van Meijgaarden, Chao Wang, Wim Jiskoot, Joke A. Bouwstra, Mariëlle C. Haks, Annemieke Geluk, Tom H. M. Ottenhoff	2024	2
8	Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis PLoS ONE ·Stuart Meier, James A. Seddon, Elizna Maasdorp, Léanie Kleynhans, Nelita du Plessis, André G. Loxton, Stephanus T. Malherbe, Daniel E. Zak, Ethan Thompson, Fergal J. Duffy, Stefan H. E. Kaufmann, Tom H. M. Ottenhoff, Thomas J. Scriba, Sara Suliman, Jayne S. Sutherland, Jill Winter, Helena Kuivaniemi, Gerhard Walzl, Gerard Tromp	2022	8
9	Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues The Journal of Immunology ·Paula Ruibal, Kees L. M. C. Franken, Krista E. van Meijgaarden, C Robert, Sneha Giri, Mirjam H.M. Heemskerk, Tom H. M. Ottenhoff, Simone A. Joosten	2020	25
10	Systemic and pulmonary C1q as biomarker of progressive disease in experimental non-human primate tuberculosis Scientific Reports ·Karin Dijkman, Rosalie Lubbers, Sheng He, Tom H. M. Ottenhoff, Simone A. Joosten, Leendert A. Trouw, Frank A. W. Verreck	2020	15
11	Bioorthogonal Correlative Light-Electron Microscopy of Mycobacterium tuberculosis in Macrophages Reveals the Effect of Antituberculosis Drugs on Subcellular Bacterial Distribution ACS Central Science ·モティウルラーマン, Iva Bradáčková, Erik Bos, 张崇, Mulliken, Kimberley V. Walburg, Suzanne van Veen, Abha Mittal, Irene Hösli-Krais, Mariëlle C. Haks, Tom H. M. Ottenhoff, Abraham J. Koster, Sander I. van Kasteren	2020	14
12	Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction PLoS Pathogens ·Frank Vrieling, Louis Wilson, Patrick C.N. Rensen, Gerhard Walzl, Tom H. M. Ottenhoff, Simone A. Joosten	2019	38
13	OC 8435 MULTI-BIOMARKER TEST STRIP FOR POINT-OF-CARE SCREENING FOR ACTIVE TUBERCULOSIS: A FIVE-COUNTRY MULTI-CENTRE TEST EVALUATION BMJ Global Health ·Paul L. A. M. Corstjens, Anouk van Hooij, Elisa M. Tjon Kon Fat, Akhmadjon Makhsumkhanov, A. Martens, Azaria Diergaardt, Hygon Mutavhatsindi, Awa Gindeh, Adane Mihret, 津端捷夫, Gunar Günther, Rawleigh Howe, Harriet Mayanja‐Kizza, Jayne S. Sutherland, Novel N. Chegou, Tom H. M. Ottenhoff, Gerhard Walzl, Annemieke Geluk	2019	2
14	Identification of a systemic interferon-γ inducible antimicrobial gene signature in leprosy patients undergoing reversal reaction PLoS neglected tropical diseases ·Rosane M. B. Teles, Jing Lü, park ryeok, Isabela Maria Bernardes Goulart, Sayera Banu, Deanna A. Hagge, Kidist Bobosha, Tom H. M. Ottenhoff, Matteo Pellegrini, Annemieke Geluk, Robert L. Modlin	2019	24
15	Patients with Concurrent Tuberculosis and Diabetes Have a Pro-Atherogenic Plasma Lipid Profile EBioMedicine ·Frank Vrieling, Katharina Ronacher, Léanie Kleynhans, Erik B. van den Akker, Gerhard Walzl, Tom H. M. Ottenhoff, Simone A. Joosten	2018	41
16	NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification JCI Insight ·Emilie Barruet, Blanca M. Morales, Corey J. Cain, A. V. Sangala, Kelly L. Wentworth, Y. Tayama, Bipin Dahal, Mariëlle C. Haks, Tom H. M. Ottenhoff, Judith Hellman, Mary C. Nakamura, Edward C. Hsiao	2018	67
17	Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children Scientific Reports ·Antonio Soler-Jimenez, Synne Jenum, Dhanasekaran Sivakumaran, Aparna Mukherjee, Ragini Macaden, S. K. Kabra, Rakesh Lodha, Tom H. M. Ottenhoff, Mariëlle C. Haks, T. Mark Doherty, Christian Ritz, Harleen M. S. Grewal	2017	29
18	A dose-dependent plasma signature of the safety and immunogenicity of the rVSV-Ebola vaccine in Europe and Africa Science Translational Medicine ·Angela Huttner, Christophe Combescure, Stéphane Grillet, Mariëlle C. Haks, Edwin Quinten, Christine Modoux, Sélidji Todagbé Agnandji, Jessica S. Brosnahan, Julie-Anne Dayer, Ali M. Harandi, Laurent Kaiser, Donata Medaglini, T P Monath, (unknown), Pascale Roux‐Lombard, Peter G. Kremsner, Tom H. M. Ottenhoff, Claire‐Anne Siegrist	2017	43
19	Identification of a human CD8 ⁺ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4 Proceedings of the National Academy of Sciences ·Simone A. Joosten, Krista E. van Meijgaarden, Nigel D. L. Savage, Tjitske de Boer, Frédéric Triebel, Annemieke van der Wal, Emile de Heer, Michèl R. Klein, Annemieke Geluk, Tom H. M. Ottenhoff	2007	157
20	Leprosy bacillus triggers the wrong cells. PubMed ·Tom H. M. Ottenhoff, Michèl R. Klein	2005	2

About Tom H. M. Ottenhoff

Tom H. M. Ottenhoff is a scholar working on Infectious Diseases, Immunology, Epidemiology, Molecular Medicine and Surgery, having authored 471 papers that have together received 25.8k indexed citations. Recurring topics across this work include Tuberculosis Research and Epidemiology (271 papers), Mycobacterium research and diagnosis (204 papers), Immune Cell Function and Interaction (77 papers), Immunodeficiency and Autoimmune Disorders (74 papers), T-cell and B-cell Immunology (62 papers), Leprosy Research and Treatment (55 papers), Immunotherapy and Immune Responses (46 papers) and Infectious Diseases and Tuberculosis (45 papers). The work is most often cited by research in Infectious Diseases (13.8k citations), Immunology (12.8k citations), Epidemiology (11.2k citations), Virology (555 citations) and Microbiology (614 citations). Tom H. M. Ottenhoff has collaborated with scholars based in Netherlands, United Kingdom and United States. Frequent co-authors include Simone A. Joosten, Krista E. van Meijgaarden, Annemieke Geluk, Kees L. M. C. Franken, Jaap T. van Dissel, Tjitske de Boer, Frank A. W. Verreck, Stefan H. E. Kaufmann, Marieke A. Hoeve and J.W.M. van der Meer. Their work appears in journals such as Frontiers in Immunology, The Journal of Immunology, PLoS ONE, European Journal of Immunology and Infection and Immunity.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact