Alessandro Sette

121.5k total citations · 35 hit papers
858 papers, 72.2k citations indexed

About

Alessandro Sette is a scholar working on Immunology, Molecular Biology and Infectious Diseases. According to data from OpenAlex, Alessandro Sette has authored 858 papers receiving a total of 72.2k indexed citations (citations by other indexed papers that have themselves been cited), including 545 papers in Immunology, 332 papers in Molecular Biology and 188 papers in Infectious Diseases. Recurrent topics in Alessandro Sette's work include Immunotherapy and Immune Responses (344 papers), vaccines and immunoinformatics approaches (293 papers) and T-cell and B-cell Immunology (234 papers). Alessandro Sette is often cited by papers focused on Immunotherapy and Immune Responses (344 papers), vaccines and immunoinformatics approaches (293 papers) and T-cell and B-cell Immunology (234 papers). Alessandro Sette collaborates with scholars based in United States, Italy and Australia. Alessandro Sette's co-authors include John Sidney, Bjoern Peters, Scott Southwood, Howard M. Grey, Shane Crotty, Daniela Weiskopf, Søren Buus, Jason Greenbaum, Huynh‐Hoa Bui and Ettore Appella and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Alessandro Sette

840 papers receiving 71.0k citations

Hit Papers

Targets of ... 1987 2026 2000 2013 2020 2018 2008 2021 2014 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
    2020 2.2k citations Alba Grifoni, Daniela Weiskopf et al. profile →
  2. The Immune Epitope Database (IEDB): 2018 update
    2018 1.3k citations Alessandro Sette, Bjoern Peters et al. profile →
  3. ElliPro: a new structure-based tool for the prediction of antibody epitopes
    2008 1.2k citations Alessandro Sette, Bjoern Peters et al. profile →
  4. Adaptive immunity to SARS-CoV-2 and COVID-19
    2021 1.1k citations Alessandro Sette, Shane Crotty profile →
  5. The immune epitope database (IEDB) 3.0
    2014 803 citations Jason Greenbaum, Alessandro Sette et al. profile →
  6. The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.
    1994 724 citations Alessandro Sette, Carla Oseroff et al. The Journal of Immunology profile →
  7. A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach
    2008 659 citations John Sidney, Alessandro Sette et al. profile →
  8. A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2
    2020 652 citations Alba Grifoni, John Sidney et al. Cell Host & Microbe profile →
  9. Predicting population coverage of T-cell epitope-based diagnostics and vaccines
    2006 639 citations John Sidney, Scott Southwood et al. profile →
  10. Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses
    2013 625 citations Colin Havenar‐Daughton, Cecilia S. Lindestam Arlehamn et al. profile →
  11. Properties of MHC Class I Presented Peptides That Enhance Immunogenicity
    2013 623 citations Jason Greenbaum, Daniela Weiskopf et al. profile →
  12. The Relation Between Major Histocompatibility Complex (MHC) Restriction and the Capacity of Ia to Bind Immunogenic Peptides
    1987 597 citations Alessandro Sette, Howard M. Grey et al. Science profile →
  13. Identifying specificity groups in the T cell receptor repertoire
    2017 595 citations Cecilia S. Lindestam Arlehamn, Alessandro Sette et al. profile →
  14. Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndrome
    2020 587 citations Daniela Weiskopf, Alba Grifoni et al. profile →
  15. Peptides Presented to the Immune System by the Murine Class II Major Histocompatibility Complex Molecule I-A d
    1992 566 citations Ettore Appella, Howard M. Grey et al. Science profile →
  16. Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia
    2000 565 citations Alessandro Sette et al. profile →
  17. Several Common HLA-DR Types Share Largely Overlapping Peptide Binding Repertoires
    1998 556 citations Scott Southwood, John Sidney et al. The Journal of Immunology profile →
  18. NetMHCpan, a method for MHC class I binding prediction beyond humans
    2008 546 citations Bjoern Peters, John Sidney et al. profile →
  19. Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules
    1993 542 citations John Sidney, Esteban Celis et al. profile →
  20. HLA class I supertypes: a revised and updated classification
    2008 542 citations John Sidney, Bjoern Peters et al. profile →
  21. Cutting Edge: The Conversion of Arginine to Citrulline Allows for a High-Affinity Peptide Interaction with the Rheumatoid Arthritis-Associated HLA-DRB1*0401 MHC Class II Molecule
    2003 541 citations Scott Southwood, Alessandro Sette et al. The Journal of Immunology profile →
  22. Improved methods for predicting peptide binding affinity to MHC class II molecules
    2018 530 citations Jason Greenbaum, Alessandro Sette et al. Immunology profile →
  23. The Immune Epitope Database 2.0
    2009 527 citations Jason Greenbaum, Alessandro Sette et al. profile →
  24. Peptide binding predictions for HLA DR, DP and DQ molecules
    2010 526 citations John Sidney, Alessandro Sette et al. profile →
  25. Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism
    1999 520 citations Alessandro Sette, John Sidney profile →
  26. SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron
    2022 484 citations Jennifer M. Dan, Elizabeth J. Phillips et al. profile →
  27. Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8 + T cells
    2013 454 citations Daniela Weiskopf, John Sidney et al. Proceedings of the National Academy of Sciences profile →
  28. The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design
    2017 360 citations Bjoern Peters, Alessandro Sette et al. profile →
  29. Humoral and cellular immune memory to four COVID-19 vaccines
    2022 331 citations Jennifer M. Dan, Alba Grifoni et al. profile →
  30. The Outcome of Hepatitis C Virus Infection Is Predicted by Escape Mutations in Epitopes Targeted by Cytotoxic T Lymphocytes
    2001 321 citations John Sidney, Alessandro Sette et al. profile →
  31. IEDB-AR: immune epitope database—analysis resource in 2019
    2019 264 citations Jason Greenbaum, Alessandro Sette et al. profile →
  32. SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19
    2021 204 citations Alba Grifoni, John Sidney et al. Cell Host & Microbe profile →
  33. Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer
    2021 197 citations Christiane S. Eberhardt, John Sidney et al. profile →
  34. Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines
    2022 152 citations Alessandro Sette, Shane Crotty profile →
  35. T Cell Responses to SARS-CoV-2
    2023 83 citations Alessandro Sette, John Sidney et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Alessandro Sette United States 142 40.0k 29.6k 17.2k 14.2k 11.5k 858 72.2k
Rafi Ahmed United States 137 55.3k 1.4× 12.3k 0.4× 10.0k 0.6× 15.0k 1.1× 2.4k 0.2× 469 76.0k
Antonio Lanzavecchia Switzerland 129 57.5k 1.4× 13.1k 0.4× 8.2k 0.5× 9.6k 0.7× 5.3k 0.5× 349 77.0k
John Sidney United States 101 19.4k 0.5× 14.7k 0.5× 6.6k 0.4× 7.1k 0.5× 5.3k 0.5× 387 33.1k
Joseph Sodroski United States 118 27.5k 0.7× 15.8k 0.5× 19.0k 1.1× 9.9k 0.7× 8.4k 0.7× 446 56.3k
Michel C. Nussenzweig United States 136 39.4k 1.0× 20.1k 0.7× 6.9k 0.4× 5.0k 0.4× 7.8k 0.7× 379 61.3k
Robert C. Gallo United States 128 35.1k 0.9× 18.7k 0.6× 18.5k 1.1× 13.3k 0.9× 3.7k 0.3× 700 76.9k
Dennis R. Burton United States 127 19.8k 0.5× 21.9k 0.7× 12.9k 0.7× 11.1k 0.8× 18.4k 1.6× 481 54.4k
Andrew J. McMichael United Kingdom 109 33.7k 0.8× 8.9k 0.3× 8.4k 0.5× 11.9k 0.8× 2.8k 0.2× 471 49.5k
Charles M. Rice United States 140 13.1k 0.3× 16.8k 0.6× 16.0k 0.9× 27.4k 1.9× 6.0k 0.5× 476 67.0k
Ralph M. Steinman United States 150 73.0k 1.8× 20.9k 0.7× 4.8k 0.3× 7.3k 0.5× 4.1k 0.4× 377 89.6k

Countries citing papers authored by Alessandro Sette

Since Specialization
Citations

This map shows the geographic impact of Alessandro Sette's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alessandro Sette with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alessandro Sette more than expected).

Fields of papers citing papers by Alessandro Sette

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alessandro Sette. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alessandro Sette. The network helps show where Alessandro Sette may publish in the future.

Co-authorship network of co-authors of Alessandro Sette

This figure shows the co-authorship network connecting the top 25 collaborators of Alessandro Sette. A scholar is included among the top collaborators of Alessandro Sette based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alessandro Sette. Alessandro Sette is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Willemsen, Lisa, et al.. (2025). Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop. Nature Communications. 16(1). 3132–3132. 3 indexed citations
2.
Adamo, Sarah, Yu Gao, Takuya Sekine, et al.. (2023). Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox. Cell Host & Microbe. 31(6). 928–936.e4. 25 indexed citations
3.
Mitsi, Elena, Mariana O. Diniz, Jesús Reiné, et al.. (2023). Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination. Nature Communications. 14(1). 6815–6815. 30 indexed citations
4.
Antunes, Ricardo da Silva, Daniela Weiskopf, John Sidney, et al.. (2023). The MegaPool Approach to Characterize Adaptive CD4+ and CD8+ T Cell Responses. Current Protocols. 3(11). e934–e934. 13 indexed citations
5.
Roy, Payel, John Sidney, Cecilia S. Lindestam Arlehamn, et al.. (2022). Immunodominant MHC-II (Major Histocompatibility Complex II) Restricted Epitopes in Human Apolipoprotein B. Circulation Research. 131(3). 258–276. 12 indexed citations
6.
Kuan, Rebecca, Elizabeth J. Phillips, S. Mallal, et al.. (2022). Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profile. HLA. 101(2). 124–137. 10 indexed citations
7.
Ribeiro, Susan Pereira, Rafael Ribeiro Almeida, Luís Carlos de Souza Ferreira, et al.. (2021). A promiscuous T cell epitope-based HIV vaccine providing redundant population coverage of the HLA class II elicits broad, polyfunctional T cell responses in nonhuman primates. Vaccine. 40(2). 239–246. 3 indexed citations
8.
Lauper, Kim, Gautier Bréville, Rachel Goldstein, et al.. (2021). Robust T-Cell Responses in Anti-CD20-Treated Patients Following COVID-19 Vaccination: A Prospective Cohort Study. Clinical Infectious Diseases. 75(1). e1037–e1045. 73 indexed citations
9.
Koşaloğlu, Zeynep, John Sidney, William D. Chronister, Bjoern Peters, & Alessandro Sette. (2020). Comparison of HLA ligand elution data and binding predictions reveals varying prediction performance for the multiple motifs recognized by HLA‐DQ2.5. Immunology. 162(2). 235–247. 7 indexed citations
10.
Vries, Rory D. de, John Sidney, Paul Rubiro, et al.. (2020). Identification and Characterization of CD4 + T Cell Epitopes after Shingrix Vaccination. Journal of Virology. 94(24). 18 indexed citations
11.
Cheloha, Ross W., Andrew W. Woodham, Djenet Bousbaine, et al.. (2019). Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids. The Journal of Immunology. 203(6). 1619–1628. 10 indexed citations
12.
Dan, Jennifer M., Colin Havenar‐Daughton, Kayla Kendric, et al.. (2019). Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant T FH cells. Science Translational Medicine. 11(478). 84 indexed citations
13.
Sette, Alessandro. (2018). L’Albania nella strategia diplomatica italiana (1871-1915). 102(1). 321–378.
14.
McElroy, Anita K., Rama Akondy, Jessica R. Harmon, et al.. (2017). A Case of Human Lassa Virus Infection With Robust Acute T-Cell Activation and Long-Term Virus-Specific T-Cell Responses. The Journal of Infectious Diseases. 215(12). 1862–1872. 49 indexed citations
15.
Liepe, Juliane, Fabio Marino, John Sidney, et al.. (2016). A large fraction of HLA class I ligands are proteasome-generated spliced peptides. Science. 354(6310). 354–358. 270 indexed citations
16.
Schreiber, Karin, Ainhoa Arina, Boris Engels, et al.. (2012). Spleen Cells from Young but Not Old Immunized Mice Eradicate Large Established Cancers. Clinical Cancer Research. 18(9). 2526–2533. 21 indexed citations
17.
Assarsson, Erika, Jason Greenbaum, Magnus Sundström, et al.. (2008). Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes. Proceedings of the National Academy of Sciences. 105(6). 2140–2145. 144 indexed citations
18.
Lewinsohn, Deborah A., Gwendolyn Swarbrick, Matthew S. Cook, et al.. (2007). Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B. PLoS Pathogens. 3(9). e127–e127. 112 indexed citations
19.
Kawashima, Ichiro, Van Tsai, Scott Southwood, et al.. (1999). Identification of HLA-A3-restricted cytotoxic T lymphocyte epitopes from carcinoembryonic antigen and HER-2/neu by primary in vitro immunization with peptide-pulsed dendritic cells.. PubMed. 59(2). 431–5. 109 indexed citations
20.
Yang, Rongcun, Jehad Charo, Fumiko Ichihara, et al.. (1998). Identification of HER2/neu-derived peptide epitopes recognized by gastric cancer-specific cytotoxic T lymphocytes. International Journal of Cancer. 78(2). 202–208. 78 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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