Lorin A. Thompson

3.7k total citations · 1 hit paper
40 papers, 2.4k citations indexed

About

Lorin A. Thompson is a scholar working on Molecular Biology, Organic Chemistry and Physiology. According to data from OpenAlex, Lorin A. Thompson has authored 40 papers receiving a total of 2.4k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 12 papers in Organic Chemistry and 11 papers in Physiology. Recurrent topics in Lorin A. Thompson's work include Chemical Synthesis and Analysis (12 papers), Alzheimer's disease research and treatments (11 papers) and Computational Drug Discovery Methods (9 papers). Lorin A. Thompson is often cited by papers focused on Chemical Synthesis and Analysis (12 papers), Alzheimer's disease research and treatments (11 papers) and Computational Drug Discovery Methods (9 papers). Lorin A. Thompson collaborates with scholars based in United States, United Kingdom and Netherlands. Lorin A. Thompson's co-authors include Jonathan A. Ellman, Constantine G. Boojamra, Jeremy H. Toyn, W. Hunter White, Paul L. Gunyuzlu, Gregory Hollis, Joanne J. Bronson, F. Christopher Zusi, Richard E. Olson and Charles F. Albright and has published in prestigious journals such as Chemical Reviews, Journal of Biological Chemistry and Journal of Neuroscience.

In The Last Decade

Lorin A. Thompson

40 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Synthesis and Applications of Small Molecule Libraries

1996 1.3k citations Lorin A. Thompson et al. profile →

Peers

Lorin A. Thompson

PHARM

CTM

Christopher W. am Ende United States

Andrew P. Combs United States

Pierfausto Seneci Italy

Youhei Sohma Japan

Thierry Besson France

Antonia F. Stepan United States

Henrik H. Jensen Denmark

Hai‐Bing Zhou China

Gregory P. Roth United States

Tohru Fukuyama Japan

Christopher W. am Ende United States

Lorin A. Thompson

1.3k ×0.8

1.7k ×1.1

172 ×0.7

PHARM

155 ×0.8

186 ×1.0

CTM

Citations per year, relative to Lorin A. Thompson Lorin A. Thompson (= 1×) peers Christopher W. am Ende

Countries citing papers authored by Lorin A. Thompson

Since Specialization

Citations

This map shows the geographic impact of Lorin A. Thompson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lorin A. Thompson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lorin A. Thompson more than expected).

Fields of papers citing papers by Lorin A. Thompson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lorin A. Thompson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lorin A. Thompson. The network helps show where Lorin A. Thompson may publish in the future.

Co-authorship network of co-authors of Lorin A. Thompson

This figure shows the co-authorship network connecting the top 25 collaborators of Lorin A. Thompson. A scholar is included among the top collaborators of Lorin A. Thompson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lorin A. Thompson. Lorin A. Thompson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Rojas, Luis Alejandro, Ning Shen, Alan P. Robertson, et al.. (2020). p38α Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy. Journal of Pharmacology and Experimental Therapeutics. 374(3). 489–498. 34 indexed citations

Wu, Yong‐Jin, Brian L. Venables, Ramkumar Rajamani, et al.. (2018). Discovery of morpholine-based aryl sulfonamides as Nav1.7 inhibitors. Bioorganic & Medicinal Chemistry Letters. 28(5). 958–962. 6 indexed citations

Wu, Yong‐Jin, Brian L. Venables, Jie Chen, et al.. (2018). Discovery of new indole-based acylsulfonamide Nav1.7 inhibitors. Bioorganic & Medicinal Chemistry Letters. 29(4). 659–663. 5 indexed citations

Robertson, Alan S., Lawrence G. Iben, Cong Wei, et al.. (2017). Synergistic inhibition of Aβ production by combinations of γ-secretase modulators. European Journal of Pharmacology. 812. 104–112. 3 indexed citations

Wu, Yong‐Jin, Ramkumar Rajamani, Jeremy H. Toyn, et al.. (2016). Discovery of furo[2,3-d][1,3]thiazinamines as beta amyloid cleaving enzyme-1 (BACE1) inhibitors. Bioorganic & Medicinal Chemistry Letters. 26(23). 5729–5731. 14 indexed citations

Thakker, Deepak R., Sethu Sankaranarayanan, Marcy R. Weatherspoon, et al.. (2015). Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice. Journal of Neuroscience. 35(17). 6931–6936. 26 indexed citations

Zuev, Dmitry, Li Xu, Kimberley A. Lentz, et al.. (2015). Design and optimization of tricyclic gamma-secretase modulators. Bioorganic & Medicinal Chemistry Letters. 26(5). 1498–1502. 11 indexed citations

Wu, Yong‐Jin, Yunhui Zhang, Weixu Zhai, et al.. (2015). Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE). Bioorganic & Medicinal Chemistry Letters. 25(22). 5040–5047. 13 indexed citations

Kiefer, Susan E., ChiehYing Chang, Mian Gao, et al.. (2014). The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor. Acta Crystallographica Section F Structural Biology Communications. 70(2). 173–181. 20 indexed citations

10.

Toyn, Jeremy H., Jere E. Meredith, Donna M. Barten, et al.. (2011). Monosubstituted γ-lactam and conformationally constrained 1,3-diaminopropan-2-ol transition-state isostere inhibitors of β-secretase (BACE). Bioorganic & Medicinal Chemistry Letters. 21(22). 6916–6924. 16 indexed citations

11.

Wu, Yong‐Jin, Yunhui Zhang, Andrew C. Good, et al.. (2009). Synthesis and SAR of hydroxyethylamine based phenylcarboxyamides as inhibitors of BACE. Bioorganic & Medicinal Chemistry Letters. 19(10). 2654–2660. 11 indexed citations

12.

Yang, Michael G., J. SCOTT WELLS, Brian M. Cochran, et al.. (2007). Design and synthesis of benzoazepinone-derived cyclic malonamides and aminoamides as potent γ-secretase inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(14). 3910–3915. 12 indexed citations

13.

Thompson, Lorin A., Ann Y. Liauw, Stephen E. Mercer, et al.. (2006). Synthesis and evaluation of succinoyl-caprolactam γ-secretase inhibitors. Bioorganic & Medicinal Chemistry Letters. 16(9). 2357–2363. 14 indexed citations

14.

Thompson, Lorin A., Joanne J. Bronson, & F. Christopher Zusi. (2005). Progress in the Discovery of BACE Inhibitors. Current Pharmaceutical Design. 11(26). 3383–3404. 40 indexed citations

15.

Voss, Matthew E., Percy H. Carter, Andrew J. Tebben, et al.. (2003). Both 5-arylidene-2-thioxodihydropyrimidine-4,6(1H,5H)-diones and 3-thioxo-2,3-dihydro-1H-imidazo[1,5-a]indol-1-ones are light-Dependent tumor necrosis factor-α antagonists. Bioorganic & Medicinal Chemistry Letters. 13(3). 533–538. 58 indexed citations

16.

Marcinkeviciene, Jovita, Lisa M. Kopcho, Tao Yang, et al.. (2002). Novel Inhibition of Porcine Pepsin by a Substituted Piperidine. Journal of Biological Chemistry. 277(32). 28677–28682. 9 indexed citations

17.

Blat, Yuval, Jere E. Meredith, Qian Wang, et al.. (2002). Mutations at the P1′ position of Notch1 decrease intracellular domain stability rather than cleavage by γ-secretase. Biochemical and Biophysical Research Communications. 299(4). 569–573. 13 indexed citations

18.

Berechid, Bridget E., Magali Kitzmann, Daniel R. Foltz, et al.. (2002). Identification and Characterization of Presenilin-independent Notch Signaling. Journal of Biological Chemistry. 277(10). 8154–8165. 44 indexed citations

19.

Toyn, Jeremy H., Paul L. Gunyuzlu, W. Hunter White, Lorin A. Thompson, & Gregory Hollis. (2000). A counterselection for the tryptophan pathway in yeast: 5-fluoroanthranilic acid resistance. Yeast. 16(6). 553–560. 101 indexed citations

20.

Toyn, Jeremy H., Paul L. Gunyuzlu, W. Hunter White, Lorin A. Thompson, & Gregory Hollis. (2000). A counterselection for the tryptophan pathway in yeast: 5‐fluoroanthranilic acid resistance. Yeast. 16(6). 553–560. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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