Marc Therrien

7.9k total citations · 2 hit papers
55 papers, 5.7k citations indexed

About

Marc Therrien is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Oncology. According to data from OpenAlex, Marc Therrien has authored 55 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 48 papers in Molecular Biology, 11 papers in Cellular and Molecular Neuroscience and 6 papers in Oncology. Recurrent topics in Marc Therrien's work include Protein Kinase Regulation and GTPase Signaling (22 papers), Melanoma and MAPK Pathways (21 papers) and Neurobiology and Insect Physiology Research (10 papers). Marc Therrien is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (22 papers), Melanoma and MAPK Pathways (21 papers) and Neurobiology and Insect Physiology Research (10 papers). Marc Therrien collaborates with scholars based in Canada, United States and France. Marc Therrien's co-authors include Hugo Lavoie, Gerald M. Rubin, Jessica K. Gagnon, Jacques Drouin, David A. Wassarman, Frank Sicheri, Malha Sahmi, Felix Karim, Deborah K. Morrison and Henry C. Chang and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Marc Therrien

55 papers receiving 5.6k citations

Hit Papers

ERK signalling: a master regulator of cell beha... 2015 2026 2018 2022 2020 2015 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. ERK signalling: a master regulator of cell behaviour, life and fate
    2020 709 citations Hugo Lavoie, Marc Therrien et al. Nature Reviews Molecular Cell Biology profile →
  2. Regulation of RAF protein kinases in ERK signalling
    2015 480 citations Hugo Lavoie, Marc Therrien Nature Reviews Molecular Cell Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Marc Therrien Canada 34 4.7k 884 752 643 508 55 5.7k
Hilary McLauchlan United Kingdom 13 3.2k 0.7× 821 0.9× 775 1.0× 537 0.8× 324 0.6× 16 4.6k
Morten Frödin Denmark 28 3.9k 0.8× 533 0.6× 632 0.8× 428 0.7× 222 0.4× 42 4.8k
Jens Peter von Kries Germany 32 5.0k 1.1× 552 0.6× 878 1.2× 315 0.5× 388 0.8× 86 6.2k
Piero Crespo Spain 38 5.6k 1.2× 1.4k 1.6× 1.3k 1.7× 736 1.1× 317 0.6× 97 7.2k
Neil Q. McDonald United Kingdom 47 4.2k 0.9× 1.0k 1.1× 903 1.2× 1.1k 1.7× 194 0.4× 100 6.6k
Peter Cron Switzerland 22 5.5k 1.2× 991 1.1× 704 0.9× 421 0.7× 392 0.8× 24 6.5k
Alastair D. Reith United Kingdom 35 4.6k 1.0× 1.2k 1.4× 657 0.9× 936 1.5× 210 0.4× 52 7.1k
Tiliang Deng United States 16 3.9k 0.8× 579 0.7× 987 1.3× 485 0.8× 245 0.5× 20 5.0k
Hugh Paterson United Kingdom 29 5.3k 1.1× 1.8k 2.0× 1.4k 1.8× 519 0.8× 258 0.5× 52 6.7k
Kendall Blumer United States 47 6.7k 1.4× 1.5k 1.7× 522 0.7× 1.3k 2.1× 192 0.4× 107 8.1k

Countries citing papers authored by Marc Therrien

Since Specialization
Citations

This map shows the geographic impact of Marc Therrien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marc Therrien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marc Therrien more than expected).

Fields of papers citing papers by Marc Therrien

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marc Therrien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marc Therrien. The network helps show where Marc Therrien may publish in the future.

Co-authorship network of co-authors of Marc Therrien

This figure shows the co-authorship network connecting the top 25 collaborators of Marc Therrien. A scholar is included among the top collaborators of Marc Therrien based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Marc Therrien. Marc Therrien is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Lavoie, Hugo, Ting Jin, Marion Décossas, et al.. (2025). BRAF oncogenic mutants evade autoinhibition through a common mechanism. Science. 388(6750). eadp2742–eadp2742. 2 indexed citations
2.
Tremblay, Michel G., et al.. (2024). Tao and Rap2l ensure proper Misshapen activation and levels during Drosophila border cell migration. Developmental Cell. 60(1). 119–132.e6. 1 indexed citations
3.
Daou, Salima, Haithem Barbour, Louis Masclef, et al.. (2018). Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1. Nature Communications. 9(1). 4385–4385. 41 indexed citations
4.
Lavoie, Hugo, Malha Sahmi, Pierre Maisonneuve, et al.. (2018). MEK drives BRAF activation through allosteric control of KSR proteins. Nature. 554(7693). 549–553. 99 indexed citations
5.
Jin, Ting, et al.. (2017). RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition. Nature Communications. 8(1). 1211–1211. 68 indexed citations
6.
Baril, Caroline, et al.. (2016). Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila. Developmental Biology. 421(1). 16–26. 14 indexed citations
7.
Ashton‐Beaucage, Dariel & Marc Therrien. (2016). How Genetics Has Helped Piece Together the MAPK Signaling Pathway. Methods in molecular biology. 1487. 1–21. 10 indexed citations
8.
Lavoie, Hugo & Marc Therrien. (2015). Regulation of RAF protein kinases in ERK signalling. Nature Reviews Molecular Cell Biology. 16(5). 281–298. 480 indexed citations breakdown →
9.
Lavoie, Hugo, et al.. (2014). Dimerization-induced allostery in protein kinase regulation. Trends in Biochemical Sciences. 39(10). 475–486. 77 indexed citations
10.
Ashton‐Beaucage, Dariel, Christian M. Udell, Hugo Lavoie, et al.. (2010). The Exon Junction Complex Controls the Splicing of mapk and Other Long Intron-Containing Transcripts in Drosophila. Cell. 143(2). 251–262. 100 indexed citations
11.
Caron, Étienne, Samik Ghosh, Yukiko Matsuoka, et al.. (2010). A comprehensive map of the mTOR signaling network. Molecular Systems Biology. 6(1). 453–453. 193 indexed citations
12.
Douziech, Mélanie, Malha Sahmi, Gino Laberge, & Marc Therrien. (2006). A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila. Genes & Development. 20(7). 807–819. 49 indexed citations
13.
Baril, Caroline & Marc Therrien. (2006). Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila. Developmental Biology. 294(1). 232–245. 20 indexed citations
14.
Therrien, Marc, et al.. (2002). MAP Kinase Module: The Ksr Connection. Current Biology. 12(9). R325–R327. 23 indexed citations
15.
Laberge, Gino, et al.. (2002). KSR is a scaffold required for activation of the ERK/MAPK module. Genes & Development. 16(4). 427–438. 182 indexed citations
16.
Karim, Felix, Henry C. Chang, Marc Therrien, et al.. (1996). A Screen for Genes That Function Downstream of Ras1 During Drosophila Eye Development. Genetics. 143(1). 315–329. 207 indexed citations
17.
Therrien, Marc, Neil R. Michaud, Gerald M. Rubin, & Deborah K. Morrison. (1996). KSR modulates signal propagation within the MAPK cascade.. Genes & Development. 10(21). 2684–2695. 212 indexed citations
18.
Chang, Henry C., Felix Karim, Elizabeth O’Neill, et al.. (1994). Ras Signal Transduction Pathway in Drosophila Eye Development. Cold Spring Harbor Symposia on Quantitative Biology. 59(0). 147–153. 17 indexed citations
19.
Therrien, Marc & Jacques Drouin. (1993). Cell-Specific Helix-Loop-Helix Factor Required for Pituitary Expression of the Pro-Opiomelanocortin Gene. Molecular and Cellular Biology. 13(4). 2342–2353. 30 indexed citations
20.
Therrien, Marc & Jacques Drouin. (1993). Molecular Determinants for Cell Specificity and Glucocorticoid Repression of the Proopiomelanocortin Genea. Annals of the New York Academy of Sciences. 680(1). 663–672. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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