Andrew P. McMahon

98.8k citations

366 papers · 76.4k indexed · 43 hit papers · h-index 152

Molecular Biology top 0.01%
Genetics top 0.01%
Surgery top 0.1%
Pulmonary and Respiratory Medicine top 0.1%
Cellular and Molecular Neuroscience top 0.1%

Co-authors: Jill A. McMahon Philip W. Ingham Benoit St‐Jacques Allan Bradley Shigemi Hayashi Mark Joseph Bitgood David H. Rowitch Brian A. Parr
Topics: Hedgehog Signaling Pathway Studies (125 papers)Renal and related cancers (103 papers)Developmental Biology and Gene Regulation (93 papers)
Cited by: Developmental Neuroscience Molecular Biology Developmental Biology
Journals: Nature Science New England Journal of Medicine
Partner nations: United States United Kingdom Japan

In The Last Decade

Andrew P. McMahon

362 papers receiving 75.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Hedgehog signaling in animal development: paradigms and principles

2001 2.5k citations Andrew P. McMahon et al. profile →
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 1.8k citations Andrew P. McMahon et al. profile →
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

1999 1.4k citations Andrew P. McMahon et al. profile →
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1990 1.3k citations Andrew P. McMahon et al. profile →
Canonical Wnt Signaling in Differentiated Osteoblasts Controls Osteoclast Differentiation

2005 1.2k citations Fanxin Long, Andrew P. McMahon et al. Developmental Cell profile →
HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

1995 1.1k citations Andrew P. McMahon et al. profile →
Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis

2000 1.1k citations Andrew P. McMahon et al. Development profile →
Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

2009 1.1k citations Shuei‐Liong Lin, Akio Kobayashi et al. profile →
Efficient Recombination in Diverse Tissues by a Tamoxifen-Inducible Form of Cre: A Tool for Temporally Regulated Gene Activation/Inactivation in the Mouse

2002 1.1k citations Andrew P. McMahon et al. profile →
Female development in mammals is regulated by Wnt-4 signalling

1999 972 citations Andrew P. McMahon et al. profile →
Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

2001 943 citations Mākoto Ishibashi, Andrew P. McMahon et al. Development profile →
Fate of the mammalian cardiac neural crest

2000 926 citations Andrew P. McMahon et al. Development profile →
Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

2003 855 citations Albrecht M. Clement, Minh Dang Nguyen et al. Science profile →
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

1994 852 citations Andrew P. McMahon et al. profile →
Distinct roles for Hedgehog and canonical Wnt signaling in specification,differentiation and maintenance of osteoblast progenitors

2006 821 citations Stephen J. Rodda, Andrew P. McMahon Development profile →
Evidence for an Expansion-Based Temporal Shh Gradient in Specifying Vertebrate Digit Identities

2004 805 citations Brian D. Harfe, Paul Scherz et al. profile →
A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo

1999 781 citations Andrew P. McMahon et al. Development profile →
Derivation of Embryonic Stem-Cell Lines from Human Blastocysts

2004 733 citations Jill A. McMahon, Andrew P. McMahon et al. profile →
1 Developmental roles and clinical significance of Hedgehog signaling

2003 731 citations Andrew P. McMahon, Clifford J. Tabin et al. profile →
Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds

1993 711 citations Andrew P. McMahon et al. Development profile →
Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development

2008 710 citations Akio Kobayashi, M. Todd Valerius et al. profile →
Sonic Hedgehog–Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System

2000 699 citations Andrew P. McMahon et al. profile →
Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite

1998 687 citations Jill A. McMahon, Andrew P. McMahon et al. profile →
Wnt9b Plays a Central Role in the Regulation of Mesenchymal to Epithelial Transitions Underlying Organogenesis of the Mammalian Urogenital System

2005 673 citations Thomas J. Carroll, Andrew P. McMahon et al. Developmental Cell profile →
Noggin, Cartilage Morphogenesis, and Joint Formation in the Mammalian Skeleton

1998 660 citations Jill A. McMahon, Andrew P. McMahon et al. Science profile →
Intrinsic Epithelial Cells Repair the Kidney after Injury

2008 654 citations M. Todd Valerius, Akio Kobayashi et al. profile →
Hedgehog signals regulate multiple aspects of gastrointestinal development

2000 652 citations Andrew P. McMahon et al. Development profile →
Sonic hedgehog regulates growth and morphogenesis of the tooth

2000 650 citations Andrew P. McMahon et al. Development profile →
Sonic hedgehog signaling is essential for hair development

1998 642 citations Jill A. McMahon, Andrew P. McMahon et al. profile →
Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

1999 617 citations Andrew P. McMahon et al. profile →
Dorsalizing signal Wnt-7a required for normal polarity of D–V and A–P axes of mouse limb

1995 584 citations Andrew P. McMahon et al. profile →
A mitogen gradient of dorsal midline Wnts organizes growth in the CNS

2002 579 citations Andrew P. McMahon et al. Development profile →
Wnt signalling required for expansion of neural crest and CNS progenitors

1997 576 citations Andrew P. McMahon et al. profile →
SOX2, a Persistent Marker for Multipotential Neural Stem Cells Derived from Embryonic Stem Cells, the Embryo or the Adult

2004 571 citations Andrew P. McMahon et al. profile →
Sonic Hedgehog Is Required for Progenitor Cell Maintenance in Telencephalic Stem Cell Niches

2003 565 citations Andrew P. McMahon et al. profile →
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

2008 552 citations Andrew P. McMahon et al. Development profile →
Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation

2001 545 citations Fanxin Long, Andrew P. McMahon et al. Development profile →
The Morphogen Sonic Hedgehog Is an Axonal Chemoattractant that Collaborates with Netrin-1 in Midline Axon Guidance

2003 527 citations Juhee Jeong, Andrew P. McMahon et al. profile →
Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

1987 525 citations Andrew P. McMahon et al. profile →
A local Wnt-3a signal is required for development of the mammalian hippocampus

2000 518 citations Andrew P. McMahon et al. Development profile →
Sertoli cell signaling by Desert hedgehog regulates the male germline

1996 514 citations Andrew P. McMahon et al. profile →
Sonic hedgehog regulates branching morphogenesis in the mammalian lung

1998 505 citations Andrew P. McMahon et al. profile →
The midbrain-hindbrain phenotype of Wnt-1−Wnt-1− mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum

1992 502 citations Andrew P. McMahon, Jill A. McMahon et al. profile →

Peers

Countries citing papers authored by Andrew P. McMahon

Since Specialization

Citations

This map shows the geographic impact of Andrew P. McMahon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew P. McMahon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew P. McMahon more than expected).

Fields of papers citing papers by Andrew P. McMahon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew P. McMahon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew P. McMahon. The network helps show where Andrew P. McMahon may publish in the future.

Co-authorship network of co-authors of Andrew P. McMahon

This figure shows the co-authorship network connecting the top 25 collaborators of Andrew P. McMahon. A scholar is included among the top collaborators of Andrew P. McMahon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andrew P. McMahon. Andrew P. McMahon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development 2024 ·Developmental Cell ·Sung‐Hyun Kim,Kari Koppitch,Riana K. Parvez,Jinjin Guo,(unknown),(unknown),Nils O. Lindström,Andrew P. McMahon	13
2	Developmental and Cell Fate Analyses Support a Postnatal Origin for the Cortical Collecting System in the Mouse Kidney 2024 ·Journal of the American Society of Nephrology ·Riana K. Parvez,(unknown),Jing Liu,(unknown),Elisabeth A. Rutledge,Jinjin Guo,(unknown),Andrew P. McMahon	2
3	User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium 2023 ·APL Bioengineering ·(unknown),(unknown),Cheng Song,Yibu Chen,(unknown),(unknown),(unknown),Andrew P. McMahon,Megan L. McCain	2
4	A genetic model for in vivo proximity labelling of the mammalian secretome 2022 ·Open Biology ·Rui Yang,(unknown),Ilia A. Droujinine,Namrata D. Udeshi,Yanhui Hu,Jinjin Guo,Jill A. McMahon,(unknown),(unknown),(unknown),Jihui Sha,Shishang Qin,(unknown),James Wohlschlegel,Alice Y. Ting,Steven A. Carr,Norbert Perrimon,Andrew P. McMahon	17
5	Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning 2018 ·Journal of the American Society of Nephrology ·Nils O. Lindström,Tracy Tran,Jinjin Guo,Elisabeth A. Rutledge,Riana K. Parvez,Matthew E. Thornton,Brendan H. Grubbs,Jill A. McMahon,Andrew P. McMahon	100
6	Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney 2018 ·Journal of the American Society of Nephrology ·Nils O. Lindström,Jinjin Guo,Albert D. Kim,Tracy Tran,Qiuyu Guo,Guilherme De Sena Brandine,Andrew Ransick,Riana K. Parvez,Matthew E. Thornton,(unknown),Brendan H. Grubbs,Jill A. McMahon,Andrew D. Smith,Andrew P. McMahon	139
7	Conserved and Divergent Features of Human and Mouse Kidney Organogenesis 2018 ·Journal of the American Society of Nephrology ·Nils O. Lindström,Jill A. McMahon,Jinjin Guo,Tracy Tran,Qiuyu Guo,Elisabeth A. Rutledge,Riana K. Parvez,(unknown),Robert Schuler,(unknown),Albert D. Kim,Ahmed Abdelhalim,Seth Ruffins,Matthew E. Thornton,(unknown),Brendan H. Grubbs,Carl Kesselman,Andrew P. McMahon	149
8	Macrophage Wnt7b is critical for kidney repair and regeneration 2010 ·Proceedings of the National Academy of Sciences ·Shuei‐Liong Lin,Bing Li,Sujata Rao,Eun-Jin Yeo,Thomas E. Hudson,Brian T. Nowlin,Huaying Pei,Lijun Chen,Jie Zheng,Thomas J. Carroll,Jeffrey W. Pollard,Andrew P. McMahon,Richard A. Lang,Jeremy S. Duffield	348
9	Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning 2008 ·Development ·Chester E. Chamberlain,Juhee Jeong,Chaoshe Guo,Benjamin L. Allen,Andrew P. McMahon	183
10	Canonical Wnt Signaling Regulates Organ-Specific Assembly and Differentiation of CNS Vasculature 2008 ·Science ·Jan M. Stenman,Jayaraj Rajagopal,Thomas J. Carroll,Mākoto Ishibashi,Jill A. McMahon,Andrew P. McMahon	497
11	Dicer-dependent pathways regulate chondrocyte proliferation and differentiation 2008 ·Proceedings of the National Academy of Sciences ·Tatsuya Kobayashi,Jun Lü,Bradley S. Cobb,Stephen J. Rodda,Andrew P. McMahon,Ernestina Schipani,Matthias Merkenschlager,Henry M. Kronenberg	287
12	Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning 2007 ·Development ·Steven A. Vokes,Hongkai Ji,Scott McCuine,Toyoaki Tenzen,(unknown),Sheng Zhong,William J.R. Longabaugh,Eric H. Davidson,Wing Hung Wong,Andrew P. McMahon	226
13	Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron 2007 ·Development ·Hui‐Teng Cheng,Mijin Kim,M. Todd Valerius,Kameswaran Surendran,Karin Schuster-Gossler,Achim Gossler,Andrew P. McMahon,Raphael Kopan	262
14	BMP signaling stimulates cellular differentiation at multiple steps during cartilage development 2005 ·Proceedings of the National Academy of Sciences ·Tatsuya Kobayashi,Karen M. Lyons,Andrew P. McMahon,Henry M. Kronenberg	140
15	Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development 2005 ·Development ·Akio Kobayashi,Kin Ming Kwan,Thomas J. Carroll,Andrew P. McMahon,Cathy Mendelsohn,Richard R. Behringer	281
16	Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1 2004 ·Development ·Juhee Jeong,Andrew P. McMahon	184
17	Hedgehog signaling is essential for endothelial tube formation during vasculogenesis 2004 ·Development ·Steven A. Vokes,Tatiana A. Yatskievych,Ronald L. Heimark,Jill A. McMahon,Andrew P. McMahon,Parker B. Antin,Paul A. Krieg	160
18	Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton 2004 ·Development ·Fanxin Long,Ung‐il Chung,Shinsuke Ohba,Jill A. McMahon,Henry M. Kronenberg,Andrew P. McMahon	341
19	The Limb Bud Shh-Fgf Feedback Loop Is Terminated by Expansion of Former ZPA Cells 2004 ·Science ·Paul Scherz,Brian D. Harfe,Andrew P. McMahon,Clifford J. Tabin	129
20	Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Micebreakdown → 2003 ·Science ·Albrecht M. Clement,Minh Dang Nguyen,Elizabeth A. Roberts,Michael L. Garcia,Séverine Boillée,(unknown),Andrew P. McMahon,Wilder T. Doucette,Donald Siwek,Robert J. Ferrante,Robert H. Brown,Jean‐Pierre Julien,Lawrence S.B. Goldstein,Don W. Cleveland	855

About Andrew P. McMahon

Andrew P. McMahon is a scholar working on Developmental Biology, Molecular Biology and Urology, having authored 366 papers that have together received 76.4k indexed citations. Recurring topics across this work include Hedgehog Signaling Pathway Studies (125 papers), Renal and related cancers (103 papers) and Developmental Biology and Gene Regulation (93 papers). The work is most often cited by research in Developmental Neuroscience (5.0k citations), Molecular Biology (63.0k citations) and Developmental Biology (1.7k citations). Andrew P. McMahon has collaborated with scholars based in United States, United Kingdom and Japan. Frequent co-authors include Jill A. McMahon, Philip W. Ingham, Benoit St‐Jacques, Allan Bradley, Shigemi Hayashi, Mark Joseph Bitgood, David H. Rowitch, Brian A. Parr, Thomas J. Carroll and Seppo Vainio. Their work appears in journals such as Nature, Science and New England Journal of Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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