Andrew P. McMahon

98.8k total citations · 43 hit papers
366 papers, 76.4k citations indexed

About

Andrew P. McMahon is a scholar working on Molecular Biology, Genetics and Pulmonary and Respiratory Medicine. According to data from OpenAlex, Andrew P. McMahon has authored 366 papers receiving a total of 76.4k indexed citations (citations by other indexed papers that have themselves been cited), including 325 papers in Molecular Biology, 80 papers in Genetics and 51 papers in Pulmonary and Respiratory Medicine. Recurrent topics in Andrew P. McMahon's work include Hedgehog Signaling Pathway Studies (125 papers), Renal and related cancers (103 papers) and Developmental Biology and Gene Regulation (93 papers). Andrew P. McMahon is often cited by papers focused on Hedgehog Signaling Pathway Studies (125 papers), Renal and related cancers (103 papers) and Developmental Biology and Gene Regulation (93 papers). Andrew P. McMahon collaborates with scholars based in United States, United Kingdom and Japan. Andrew P. McMahon's co-authors include Jill A. McMahon, Philip W. Ingham, Benoit St‐Jacques, Allan Bradley, Shigemi Hayashi, Mark Joseph Bitgood, David H. Rowitch, Brian A. Parr, Thomas J. Carroll and Seppo Vainio and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Andrew P. McMahon

362 papers receiving 75.2k citations

Hit Papers

Hedgehog signaling in ani... 1987 2026 2000 2013 2001 1993 1999 1990 2005 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Hedgehog signaling in animal development: paradigms and principles
    2001 2.5k citations Andrew P. McMahon et al. Genes & Development profile →
  2. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
    1993 1.8k citations Andrew P. McMahon et al. profile →
  3. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
    1999 1.4k citations Andrew P. McMahon et al. Genes & Development profile →
  4. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain
    1990 1.3k citations Andrew P. McMahon et al. profile →
  5. Canonical Wnt Signaling in Differentiated Osteoblasts Controls Osteoclast Differentiation
    2005 1.2k citations Fanxin Long, Andrew P. McMahon et al. Developmental Cell profile →
  6. HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo
    1995 1.1k citations Andrew P. McMahon et al. profile →
  7. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis
    2000 1.1k citations David H. Rowitch, Andrew P. McMahon et al. Development profile →
  8. Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis
    2009 1.1k citations Shuei‐Liong Lin, Akio Kobayashi et al. profile →
  9. Efficient Recombination in Diverse Tissues by a Tamoxifen-Inducible Form of Cre: A Tool for Temporally Regulated Gene Activation/Inactivation in the Mouse
    2002 1.1k citations Andrew P. McMahon et al. profile →
  10. Female development in mammals is regulated by Wnt-4 signalling
    1999 972 citations Andrew P. McMahon et al. profile →
  11. Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
    2001 943 citations David H. Rowitch, Andrew P. McMahon et al. Development profile →
  12. Fate of the mammalian cardiac neural crest
    2000 926 citations David H. Rowitch, Andrew P. McMahon et al. Development profile →
  13. Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice
    2003 855 citations Andrew P. McMahon et al. Science profile →
  14. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
    1994 852 citations Andrew P. McMahon et al. profile →
  15. Distinct roles for Hedgehog and canonical Wnt signaling in specification,differentiation and maintenance of osteoblast progenitors
    2006 821 citations Stephen J. Rodda, Andrew P. McMahon Development profile →
  16. Evidence for an Expansion-Based Temporal Shh Gradient in Specifying Vertebrate Digit Identities
    2004 805 citations Brian D. Harfe, Paul Scherz et al. profile →
  17. A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo
    1999 781 citations Andrew P. McMahon et al. Development profile →
  18. Derivation of Embryonic Stem-Cell Lines from Human Blastocysts
    2004 733 citations Jill A. McMahon, Andrew P. McMahon et al. profile →
  19. 1 Developmental roles and clinical significance of Hedgehog signaling
    2003 731 citations Andrew P. McMahon, Clifford J. Tabin et al. profile →
  20. Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds
    1993 711 citations Andrew P. McMahon et al. Development profile →
  21. Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development
    2008 710 citations Akio Kobayashi, M. Todd Valerius et al. profile →
  22. Sonic Hedgehog–Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System
    2000 699 citations Q. Richard Lu, John A. Alberta et al. Neuron profile →
  23. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite
    1998 687 citations Jill A. McMahon, Andrew P. McMahon et al. Genes & Development profile →
  24. Wnt9b Plays a Central Role in the Regulation of Mesenchymal to Epithelial Transitions Underlying Organogenesis of the Mammalian Urogenital System
    2005 673 citations Thomas J. Carroll, Andrew P. McMahon et al. Developmental Cell profile →
  25. Noggin, Cartilage Morphogenesis, and Joint Formation in the Mammalian Skeleton
    1998 660 citations Jill A. McMahon, Andrew P. McMahon et al. Science profile →
  26. Intrinsic Epithelial Cells Repair the Kidney after Injury
    2008 654 citations M. Todd Valerius, Akio Kobayashi et al. profile →
  27. Hedgehog signals regulate multiple aspects of gastrointestinal development
    2000 652 citations Andrew P. McMahon et al. Development profile →
  28. Sonic hedgehog regulates growth and morphogenesis of the tooth
    2000 650 citations Andrew P. McMahon et al. Development profile →
  29. Sonic hedgehog signaling is essential for hair development
    1998 642 citations Jill A. McMahon, Andrew P. McMahon et al. profile →
  30. Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein
    1999 617 citations Andrew P. McMahon et al. profile →
  31. Dorsalizing signal Wnt-7a required for normal polarity of D–V and A–P axes of mouse limb
    1995 584 citations Andrew P. McMahon et al. profile →
  32. A mitogen gradient of dorsal midline Wnts organizes growth in the CNS
    2002 579 citations Andrew P. McMahon et al. Development profile →
  33. Wnt signalling required for expansion of neural crest and CNS progenitors
    1997 576 citations Andrew P. McMahon et al. profile →
  34. SOX2, a Persistent Marker for Multipotential Neural Stem Cells Derived from Embryonic Stem Cells, the Embryo or the Adult
    2004 571 citations Andrew P. McMahon et al. profile →
  35. Sonic Hedgehog Is Required for Progenitor Cell Maintenance in Telencephalic Stem Cell Niches
    2003 565 citations Andrew P. McMahon et al. Neuron profile →
  36. Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network
    2008 552 citations Andrew P. McMahon et al. Development profile →
  37. Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation
    2001 545 citations Fanxin Long, Andrew P. McMahon et al. Development profile →
  38. The Morphogen Sonic Hedgehog Is an Axonal Chemoattractant that Collaborates with Netrin-1 in Midline Axon Guidance
    2003 527 citations Juhee Jeong, Andrew P. McMahon et al. profile →
  39. Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo
    1987 525 citations Andrew P. McMahon et al. profile →
  40. A local Wnt-3a signal is required for development of the mammalian hippocampus
    2000 518 citations Andrew P. McMahon et al. Development profile →
  41. Sertoli cell signaling by Desert hedgehog regulates the male germline
    1996 514 citations Andrew P. McMahon et al. profile →
  42. Sonic hedgehog regulates branching morphogenesis in the mammalian lung
    1998 505 citations Andrew P. McMahon et al. profile →
  43. The midbrain-hindbrain phenotype of Wnt-1−Wnt-1− mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum
    1992 502 citations Andrew P. McMahon, Jill A. McMahon et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Andrew P. McMahon United States 152 63.0k 17.5k 7.0k 6.7k 5.5k 366 76.4k
Janet Rossant Canada 130 49.6k 0.8× 11.9k 0.7× 5.4k 0.8× 2.8k 0.4× 3.7k 0.7× 397 61.8k
Roderick T. Bronson United States 139 46.0k 0.7× 8.4k 0.5× 4.6k 0.7× 5.7k 0.9× 4.4k 0.8× 544 77.8k
Neal G. Copeland United States 135 42.7k 0.7× 12.3k 0.7× 2.8k 0.4× 2.3k 0.3× 8.7k 1.6× 622 73.1k
Roel Nusse United States 99 43.6k 0.7× 8.1k 0.5× 4.1k 0.6× 2.3k 0.3× 4.7k 0.8× 208 55.1k
Shinya Yamanaka Japan 99 61.9k 1.0× 7.6k 0.4× 13.7k 2.0× 1.5k 0.2× 7.7k 1.4× 278 75.4k
Eric N. Olson United States 199 109.1k 1.7× 15.5k 0.9× 13.4k 1.9× 5.0k 0.7× 9.3k 1.7× 761 135.3k
Christer Betsholtz Sweden 100 28.8k 0.5× 3.3k 0.2× 5.8k 0.8× 4.8k 0.7× 5.3k 1.0× 327 52.3k
András Nagy Canada 90 30.1k 0.5× 7.2k 0.4× 4.1k 0.6× 2.0k 0.3× 3.2k 0.6× 396 42.2k
Nancy A. Jenkins United States 120 35.3k 0.6× 10.1k 0.6× 2.4k 0.3× 1.7k 0.3× 7.7k 1.4× 508 60.6k
Carl‐Henrik Heldin Sweden 132 41.7k 0.7× 4.7k 0.3× 4.5k 0.7× 5.7k 0.9× 2.5k 0.4× 494 62.7k

Countries citing papers authored by Andrew P. McMahon

Since Specialization
Citations

This map shows the geographic impact of Andrew P. McMahon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew P. McMahon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew P. McMahon more than expected).

Fields of papers citing papers by Andrew P. McMahon

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew P. McMahon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew P. McMahon. The network helps show where Andrew P. McMahon may publish in the future.

Co-authorship network of co-authors of Andrew P. McMahon

This figure shows the co-authorship network connecting the top 25 collaborators of Andrew P. McMahon. A scholar is included among the top collaborators of Andrew P. McMahon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andrew P. McMahon. Andrew P. McMahon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Kim, Sung‐Hyun, Kari Koppitch, Riana K. Parvez, et al.. (2024). Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development. Developmental Cell. 59(21). 2912–2930.e7. 13 indexed citations
2.
Polonsky, Michal, Louisa M.S. Gerhardt, Jina Yun, et al.. (2024). Spatial transcriptomics defines injury specific microenvironments and cellular interactions in kidney regeneration and disease. Nature Communications. 15(1). 7010–7010. 25 indexed citations
3.
4.
Cornelius, Ryan J., Xiao‐Tong Su, Jill A. McMahon, et al.. (2020). A novel distal convoluted tubule-specific Cre-recombinase driven by the NaCl cotransporter gene. American Journal of Physiology-Renal Physiology. 319(3). F423–F435. 12 indexed citations
5.
O’Brien, Lori L., Alexander N. Combes, Kieran M. Short, et al.. (2018). Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. eLife. 7. 45 indexed citations
6.
Lindström, Nils O., Jinjin Guo, Albert D. Kim, et al.. (2018). Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. Journal of the American Society of Nephrology. 29(3). 806–824. 139 indexed citations
7.
Lindström, Nils O., Jill A. McMahon, Jinjin Guo, et al.. (2018). Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. Journal of the American Society of Nephrology. 29(3). 785–805. 149 indexed citations
8.
Lin, Shuei‐Liong, Bing Li, Sujata Rao, et al.. (2010). Macrophage Wnt7b is critical for kidney repair and regeneration. Proceedings of the National Academy of Sciences. 107(9). 4194–4199. 348 indexed citations
9.
Vokes, Steven A., Hongkai Ji, Wing Hung Wong, & Andrew P. McMahon. (2008). A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb. Genes & Development. 22(19). 2651–2663. 231 indexed citations
10.
Kobayashi, Tatsuya, Jun Lü, Bradley S. Cobb, et al.. (2008). Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proceedings of the National Academy of Sciences. 105(6). 1949–1954. 287 indexed citations
11.
Cheng, Hui‐Teng, Mijin Kim, M. Todd Valerius, et al.. (2007). Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development. 134(4). 801–811. 262 indexed citations
12.
Abzhanov, Arhat, Stephen J. Rodda, Andrew P. McMahon, & Clifford J. Tabin. (2007). Regulation of skeletogenic differentiation in cranial dermal bone. Development. 134(17). 3133–3144. 168 indexed citations
13.
Mao, Junhao, Keith L. Ligon, Elena Y. Rakhlin, et al.. (2006). A Novel Somatic Mouse Model to Survey Tumorigenic Potential Applied to the Hedgehog Pathway. Cancer Research. 66(20). 10171–10178. 211 indexed citations
14.
Kobayashi, Akio, Kin Ming Kwan, Thomas J. Carroll, et al.. (2005). Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development. Development. 132(12). 2809–2823. 281 indexed citations
15.
16.
Vokes, Steven A., Tatiana A. Yatskievych, Ronald L. Heimark, et al.. (2004). Hedgehog signaling is essential for endothelial tube formation during vasculogenesis. Development. 131(17). 4371–4380. 160 indexed citations
17.
Long, Fanxin, Ung‐il Chung, Shinsuke Ohba, et al.. (2004). Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development. 131(6). 1309–1318. 341 indexed citations
18.
Scherz, Paul, Brian D. Harfe, Andrew P. McMahon, & Clifford J. Tabin. (2004). The Limb Bud Shh-Fgf Feedback Loop Is Terminated by Expansion of Former ZPA Cells. Science. 305(5682). 396–399. 129 indexed citations
19.
Bonifas, Jeannette M., Ervin H. Epstein, Sally D. Pennypacker, et al.. (2001). Activation of Expression of Hedgehog Target Genes in Basal Cell Carcinomas. Journal of Investigative Dermatology. 116(5). 739–742. 128 indexed citations
20.
Lu, Q. Richard, John A. Alberta, Zhimin Zhu, et al.. (2000). Sonic Hedgehog–Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System. Neuron. 25(2). 317–329. 699 indexed citations breakdown →

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