Alexei Degterev

16.6k total citations · 4 hit papers
88 papers, 12.2k citations indexed

About

Alexei Degterev is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Alexei Degterev has authored 88 papers receiving a total of 12.2k indexed citations (citations by other indexed papers that have themselves been cited), including 76 papers in Molecular Biology, 28 papers in Immunology and 14 papers in Oncology. Recurrent topics in Alexei Degterev's work include Cell death mechanisms and regulation (54 papers), interferon and immune responses (16 papers) and Immune Response and Inflammation (11 papers). Alexei Degterev is often cited by papers focused on Cell death mechanisms and regulation (54 papers), interferon and immune responses (16 papers) and Immune Response and Inflammation (11 papers). Alexei Degterev collaborates with scholars based in United States, China and United Kingdom. Alexei Degterev's co-authors include Junying Yuan, Michael Boyce, Gregory D. Cuny, Timothy J. Mitchison, Prakash G. Jagtap, Michael A. Moskowitz, Yaqiao Li, Noboru Mizushima, Zhihong Huang and Gerhard Wagner and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Alexei Degterev

88 papers receiving 12.0k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

2005 2.4k citations Alexei Degterev, Gregory D. Cuny et al. profile →
Identification of RIP1 kinase as a specific cellular target of necrostatins

2008 1.6k citations Alexei Degterev, Irene L. Ch’en et al. profile →
A decade of caspases

2003 893 citations Alexei Degterev, Junying Yuan et al. profile →
Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

2008 784 citations Alexei Degterev, Junying Yuan et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alexei Degterev United States	42	9.1k	3.4k	1.9k	1.5k	1.3k	88	12.2k
Sebastian Wesselborg Germany	56	7.2k 0.8×	3.9k 1.2×	2.6k 1.3×	1.6k 1.1×	1.5k 1.1×	136	13.4k
Nathanaël Larochette France	36	8.7k 1.0×	3.0k 0.9×	2.8k 1.4×	2.3k 1.6×	1.1k 0.8×	48	13.9k
Jerry E. Chipuk United States	45	9.1k 1.0×	1.8k 0.5×	1.6k 0.8×	2.6k 1.7×	1.5k 1.1×	89	12.4k
Manzoor Ahmad United States	25	8.4k 0.9×	2.7k 0.8×	1.4k 0.7×	1.7k 1.1×	1.3k 1.0×	57	11.0k
Spencer B. Gibson Canada	53	7.8k 0.9×	2.1k 0.6×	3.0k 1.6×	1.8k 1.2×	2.2k 1.7×	163	13.0k
Patrick Auberger France	52	6.5k 0.7×	1.9k 0.6×	1.6k 0.8×	2.1k 1.4×	2.1k 1.5×	193	10.5k
Atsushi Matsuzawa Japan	51	7.0k 0.8×	2.5k 0.7×	1.4k 0.7×	914 0.6×	1.6k 1.2×	124	11.3k
I. Imawati Budihardjo United States	13	9.4k 1.0×	2.0k 0.6×	1.6k 0.8×	1.8k 1.2×	1.4k 1.0×	14	12.1k
Wei‐Xing Zong United States	43	8.4k 0.9×	2.0k 0.6×	2.1k 1.1×	2.1k 1.4×	2.2k 1.6×	79	12.0k
David M. Hockenbery United States	50	10.5k 1.2×	3.2k 1.0×	1.3k 0.7×	3.6k 2.4×	2.1k 1.6×	124	16.7k

Countries citing papers authored by Alexei Degterev

Since Specialization

Citations

This map shows the geographic impact of Alexei Degterev's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alexei Degterev with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alexei Degterev more than expected).

Fields of papers citing papers by Alexei Degterev

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alexei Degterev. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alexei Degterev. The network helps show where Alexei Degterev may publish in the future.

Co-authorship network of co-authors of Alexei Degterev

This figure shows the co-authorship network connecting the top 25 collaborators of Alexei Degterev. A scholar is included among the top collaborators of Alexei Degterev based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alexei Degterev. Alexei Degterev is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hrdinka, Matouš, Lisa Schlicher, Bing Dai, et al.. (2018). Small molecule inhibitors reveal an indispensable scaffolding role of RIPK 2 in NOD 2 signaling. The EMBO Journal. 37(17). 48 indexed citations

Sriraman, Shravan Kumar, et al.. (2015). Cytotoxicity of PEGylated liposomes co-loaded with novel pro-apoptotic drug NCL-240 and the MEK inhibitor cobimetinib against colon carcinoma in vitro. Journal of Controlled Release. 220(Pt A). 160–168. 18 indexed citations

Suebsuwong, Chalada, Soumya S. Ray, Roshan J. Thapa, et al.. (2015). Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1. Cell Reports. 10(11). 1850–1860. 115 indexed citations

Liu, Q, Jianhua Qiu, Mei‐Chih Liang, et al.. (2014). Akt and mTOR mediate programmed necrosis in neurons. Cell Death and Disease. 5(2). e1084–e1084. 129 indexed citations

Degterev, Alexei, Wen Zhou, Jenny L. Maki, & Junying Yuan. (2014). Assays for Necroptosis and Activity of RIP Kinases. Methods in enzymology on CD-ROM/Methods in enzymology. 545. 1–33. 38 indexed citations

Thapa, Roshan J., Shoko Nogusa, Peirong Chen, et al.. (2013). Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases. Proceedings of the National Academy of Sciences. 110(33). E3109–18. 280 indexed citations

Xie, Tian, Wei Peng, Yexing Liu, et al.. (2013). Structural Basis of RIP1 Inhibition by Necrostatins. Structure. 21(3). 493–499. 185 indexed citations

Osafo-Addo, Awo D., Douglas Barrows, Arminja N. Kettenbach, et al.. (2013). Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis. PLoS ONE. 8(3). e56576–e56576. 62 indexed citations

Maki, Jenny L., et al.. (2013). Expression and purification of active receptor interacting protein 1 kinase using a baculovirus system. Protein Expression and Purification. 89(2). 156–161. 4 indexed citations

10.

Choi, Sung‐Woon, Heather R. Keys, Richard J. Staples, et al.. (2012). Optimization of tricyclic Nec-3 necroptosis inhibitors for in vitro liver microsomal stability. Bioorganic & Medicinal Chemistry Letters. 22(17). 5685–5688. 17 indexed citations

11.

Ofengeim, Dimitry, Peng Shi, Benchun Miao, et al.. (2012). Identification of Small Molecule Inhibitors of Neurite Loss Induced by Aβ peptide using High Content Screening. Journal of Biological Chemistry. 287(12). 8714–8723. 20 indexed citations

12.

Huang, Yue, Xiaobo Zhou, Benchun Miao, et al.. (2010). A computational framework for studying neuron morphology from in vitro high content neuron-based screening. Journal of Neuroscience Methods. 190(2). 299–309. 10 indexed citations

13.

Sánchez‐Olea, Roberto, Mónica R. Calera, & Alexei Degterev. (2009). Molecular pathways involved in cell death after chemically induced DNA damage. Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions. 99. 209–230. 5 indexed citations

14.

Ch’en, Irene L., Daniel R. Beisner, Alexei Degterev, et al.. (2008). Antigen-mediated T cell expansion regulated by parallel pathways of death. Proceedings of the National Academy of Sciences. 105(45). 17463–17468. 117 indexed citations

15.

Degterev, Alexei & Junying Yuan. (2008). Expansion and evolution of cell death programmes. Nature Reviews Molecular Cell Biology. 9(5). 378–390. 423 indexed citations

16.

Moerke, Nathan J., Hüseyin Aktaş, Han Chen, et al.. (2007). Small-Molecule Inhibition of the Interaction between the Translation Initiation Factors eIF4E and eIF4G. Cell. 128(2). 257–267. 441 indexed citations

17.

Zhang, Yong, Xiaobo Zhou, Alexei Degterev, et al.. (2007). Automated neurite extraction using dynamic programming for high-throughput screening of neuron-based assays. NeuroImage. 35(4). 1502–1515. 36 indexed citations

18.

Teng, Xin, Heather R. Keys, Arumugasamy Jeevanandam, et al.. (2007). Structure–activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(24). 6836–6840. 41 indexed citations

19.

Xiong, Guanglei, Xiaobo Zhou, Alexei Degterev, Liang Ji, & Stephen T.C. Wong. (2006). Automated neurite labeling and analysis in fluorescence microscopy images. Cytometry Part A. 69A(6). 494–505. 57 indexed citations

20.

Zhang, Yong, Xiaobo Zhou, Alexei Degterev, et al.. (2006). A novel tracing algorithm for high throughput imaging. Journal of Neuroscience Methods. 160(1). 149–162. 41 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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