Alex U. Singer

3.6k citations

28 papers · 3.0k indexed · 1 hit paper · h-index 18

Impact in

Molecular Biology top 5%
- Protein Structure and Dynamics
- RNA and protein synthesis mechanisms
- Protein Kinase Regulation and GTPase Signaling
Spectroscopy top 2%
- Advanced NMR Techniques and Applications

Papers in

Spectroscopy 6
Cell Biology 5

Co-authors: Julie D. Forman‐Kay Steven M. Pascal Lewis E. Kay Steven E. Shoelson Ranjith Muhandiram Neil A. Farrow Tony Pawson G Gish
Journals: Biochemistry (5 papers)Protein Science (4 papers)Journal of Molecular Biology (3 papers)Structure (2 papers)PLoS Pathogens (2 papers)
Partner nations: Canada United States Germany

In The Last Decade

Alex U. Singer

26 papers receiving 3.0k citations

Hit Papers

align trajectories log scale

Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation 1994 · 1.9k citations

Peers

Countries citing papers authored by Alex U. Singer

Since Specialization

Citations

This map shows the geographic impact of Alex U. Singer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alex U. Singer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alex U. Singer more than expected).

Fields of papers citing papers by Alex U. Singer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alex U. Singer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alex U. Singer. The network helps show where Alex U. Singer may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Alex U. Singer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alex U. Singer Line = papers co-authored together Alex U. Singer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structural and functional validation of a highly specific Smurf2 inhibitor Protein Science ·Tanner M. Tessier, 勝司小野, Frederic E. Fuller, 良之巽, Syeda Mahmuda, Joan Teyra, Nick Jarvik, Jacky Chung, Igor Kurinov, Frank Sicheri, Sachdev S. Sidhu, Alex U. Singer, Wei Zhang	2023	1
2	Engineered SH2 Domains for Targeted Phosphoproteomics ACS Chemical Biology ·Sara Saada, Gianluca Veggiani, Ulrike Kusebauch, Zsófia Paár, Мария Александровна Еловская, Alex U. Singer, Jiefei Tong, Jiaye Zhao, Gerald Gish, Zhi Sun, Igor Kurinov, Frank Sicheri, Michael F. Moran, Robert L. Moritz, Sachdev S. Sidhu	2022	11
3	Comprehensive Assessment of the Relationship Between Site−2 Specificity and Helix α2 in the Erbin PDZ Domain Journal of Molecular Biology ·Joan Teyra, M. A. McLaughlin, Alex U. Singer, Yiao‐Hsien Wang, Andreas Ernst, Frank Sicheri, Sachdev S. Sidhu	2021	0
4	A Panel of Engineered Ubiquitin Variants Targeting the Family of Domains Found in Ubiquitin Specific Proteases (DUSPs) Journal of Molecular Biology ·Rayén Munizaga Jara, Gianluca Veggiani, Alex U. Singer, Joan Teyra, Jacky Chung, Sachdev S. Sidhu	2021	3
5	Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities Protein Science ·Joan Teyra, Andreas Ernst, Alex U. Singer, Frank Sicheri, Sachdev S. Sidhu	2019	8
6	Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15 Structure ·Joan Teyra, Alex U. Singer, Frank W. Schmitges, Patrick Jaynes, Katherine P. Wallerius, Maria J. Polyak, Nassima Fodil, Jonathan R. Krieger, Jiefei Tong, Carsten Schwerdtfeger, Bradley Brasher, Derek F. Ceccarelli, Jason Moffat, Frank Sicheri, Michael F. Moran, Philippe Gros, Pieter J.A. Eichhorn, Martin Lenter, Guido Boehmelt, Sachdev S. Sidhu	2019	43
7	Type III Effector Activation via Nucleotide Binding, Phosphorylation, and Host Target Interaction PLoS Pathogens ·Darrell Desveaux, Alex U. Singer, В.М. Єремеєва, Brian C. McNulty, Laura W. Musselwhite, Zachary L. Nimchuk, John Sondek, Jeffery L. Dangl	2007	76
8	Correction: Type III Effector Activation via Nucleotide Binding, Phosphorylation, and Host Target Interaction PLoS Pathogens ·Darrell Desveaux, Alex U. Singer, В.М. Єремеєва, Brian C. McNulty, 構建設計研究所, Zachary L. Nimchuk, John Sondek, GK Deb	2007	1
9	Biochemical and Structural Characterization of a Novel Family of Cystathionine β-Synthase Domain Proteins Fused to a Zn Ribbon-Like Domain Journal of Molecular Biology ·Michael Proudfoot, Stephen A. Sanders, Alex U. Singer, Rongguang Zhang, Greg Brown, Andrew Binkowski, Adalberto Co Asesor Benavides Mendoza, Jonathan A. Lukin, Alexey G. Murzin, A. Joachimiak, C.H. Arrowsmith, A.M. Edwards, Alexei Savchenko, Alexander F. Yakunin	2007	42
10	Type III effector proteins: doppelgangers of bacterial virulence Current Opinion in Plant Biology ·Darrell Desveaux, Alex U. Singer, Jeffery L. Dangl	2006	45
11	The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation Proceedings of the National Academy of Sciences ·Han‐Suk Kim, Darrell Desveaux, Alex U. Singer, Priyesh Patel, John Sondek, Jeffery L. Dangl	2005	211
12	Structural Comparison of the Unstable drkN SH3 Domain and a Stable Mutant^, Biochemistry ·Irina Bezsonova, Alex U. Singer, Wing‐Yiu Choy, Martin Tollinger, Julie D. Forman‐Kay	2005	39
13	Crystal Structures of the Type III Effector Protein AvrPphF and Its Chaperone Reveal Residues Required for Plant Pathogenesis Structure ·Alex U. Singer, Darrell Desveaux, Laurie Betts, Jeff H. Chang, Zachary L. Nimchuk, Sarah R. Grant, Jeffery L. Dangl, John Sondek	2004	61
14	Structural and Biochemical Characterization of CIB1 Delineates a New Family of EF-hand-containing Proteins Journal of Biological Chemistry ·Farazi Mena, Alex U. Singer, Laurie Betts, Cheng Yang, Joseph D. Ferrara, John Sondek, Leslie V. Parise	2004	97
15	A unique fold of phospholipase C-β mediates dimerization and interaction with Gαq Nature Structural Biology ·Alex U. Singer, Gary L. Waldo, T. Kendall Harden, John Sondek	2001	84
16	pH Titration studies of an SH2 domain‐phosphopeptide complex: Unusual histidine and phosphate pK_a values Protein Science ·Alex U. Singer, Julie D. Forman‐Kay	1997	39
17	NMR structure of neuromedin C, a neurotransmitter with an amino terminal Cu^II‐, Ni^II‐binding (ATCUN) motif Journal of Peptide Research ·Tai-Ren Chen, Alex U. Singer, Julie D. Forman‐Kay, Bibudhendra Sarkar	1997	32
18	Structural and Dynamic Characterization of the Phosphotyrosine Binding Region of an Src Homology 2 Domain-Phosphopeptide Complex by NMR Relaxation, Proton Exchange, and Chemical Shift Approaches Biochemistry ·Steven M. Pascal, Toshio Yamazaki, Alex U. Singer, (unknown), Julie D. Forman‐Kay	1995	53
19	Structural and dynamic characterization of an SH2 domain-phosphopeptide complex by NMR approaches Biochemical Society Transactions ·Steven M. Pascal, Alex U. Singer, Toshio Yamazaki, Lewis E. Kay, Julie D. Forman‐Kay	1995	5
20	Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation Biochemistry ·Neil A. Farrow, Ranjith Muhandiram, Alex U. Singer, Steven M. Pascal, Cyril M. Kay, G Gish, Steven E. Shoelson, Tony Pawson, Julie D. Forman‐Kay, Lewis E. Kay Hit paper breakdown →	1994	1887

About Alex U. Singer

Alex U. Singer is a scholar working on Spectroscopy, Cell Biology, Molecular Biology, Biotechnology and Plant Science, having authored 28 papers that have together received 3.0k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (7 papers), Plant Pathogenic Bacteria Studies (6 papers), Ubiquitin and proteasome pathways (6 papers), Enzyme Structure and Function (5 papers), Plant-Microbe Interactions and Immunity (5 papers), Glycosylation and Glycoproteins Research (3 papers), Protein Kinase Regulation and GTPase Signaling (3 papers) and Legume Nitrogen Fixing Symbiosis (3 papers). The work is most often cited by research in Molecular Biology (2.2k citations), Spectroscopy (366 citations), Cell Biology (358 citations), Biophysics (101 citations) and Immunology and Allergy (70 citations). Alex U. Singer has collaborated with scholars based in Canada, United States and Germany. Frequent co-authors include Julie D. Forman‐Kay, Steven M. Pascal, Lewis E. Kay, Steven E. Shoelson, Ranjith Muhandiram, Neil A. Farrow, Tony Pawson, G Gish, Cyril M. Kay and John Sondek. Their work appears in journals such as Biochemistry, Protein Science, Journal of Molecular Biology, Structure and PLoS Pathogens.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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