Alex MacKenzie

11.5k citations

125 papers · 6.8k indexed · 4 hit papers · h-index 37

Impact in

Genetics top 1%
- Neurogenetic and Muscular Disorders Research
- Genomics and Rare Diseases
Molecular Biology top 1%
- Cell death mechanisms and regulation
- Mitochondrial Function and Pathology
- RNA modifications and cancer
- RNA Interference and Gene Delivery

Papers in

Genetics 39
- Neurogenetic and Muscular Disorders Research 37
Molecular Biology 86
- RNA modifications and cancer 31
- Cell death mechanisms and regulation 19
- Mitochondrial Function and Pathology 15
- RNA Research and Splicing 15

Co-authors: Robert G. Korneluk Stephen Baird Eric C. LaCasse Kym M. Boycott Dennis E. Bulman Megan R. Vanstone Katsuyuki Tamai Charles Lefebvre
Journals: Human Molecular Genetics (5 papers)Genomics (5 papers)Orphanet Journal of Rare Diseases (4 papers)The Science of The Total Environment (4 papers)Neurology (4 papers)
Partner nations: Canada United States Spain

In The Last Decade

Alex MacKenzie

120 papers receiving 6.7k citations

Hit Papers

align trajectories log scale

Rare-disease genetics in the era of next-generation sequencing: discovery to translation 2013 · 496 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2013 Nature Reviews Genetics
1998 Oncogene
1996 Nature
1996 Nature Genetics

Peers

Countries citing papers authored by Alex MacKenzie

Since Specialization

Citations

This map shows the geographic impact of Alex MacKenzie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alex MacKenzie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alex MacKenzie more than expected).

Fields of papers citing papers by Alex MacKenzie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alex MacKenzie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alex MacKenzie. The network helps show where Alex MacKenzie may publish in the future.

Co-authors

The 25 scholars most cited alongside Alex MacKenzie, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alex MacKenzie Line = papers co-authored together Alex MacKenzie links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A cost-utility analysis of newborn screening for spinal muscular atrophy in Canada Orphanet Journal of Rare Diseases ·Cunbo Ma, Weston Roda, Dong Lu-di, Hugh J. McMillan, Maryam Oskoui, Alex MacKenzie, Pranesh Chakraborty, Jeff Round	2025	0
2	Sewer transport conditions and their role in the decay of endogenous SARS-CoV-2 and pepper mild mottle virus from source to collection International Journal of Hygiene and Environmental Health ·Élisabeth Mercier, Patrick M. D’Aoust, Carlos Blanco, Nada Hegazy, S.P. Saravanan, Shen Wan, Lakshmi Pisharody, Elizabeth Renouf, Trinil Olivia, Tyson E. Graber, Alex MacKenzie, Robert Delatolla	2024	0
3	Urban wastewater contains a functional human antibody repertoire of mucosal origin Water Research ·Trinil Olivia, Carlos Blanco, Tristan K. Jongert, Élisabeth Mercier, Patrick M. D’Aoust, Md Pervez Kabir, Stefan Baral, Yun Jong Min, Claire Oswald, Sharon E. Straus, Alex MacKenzie, Robert Delatolla, Tyson E. Graber	2024	2
4	Impact of coagulation on SARS-CoV-2 and PMMoV viral signal in wastewater solids Environmental Science and Pollution Research ·Nada Hegazy, Xin Tian, Patrick M. D’Aoust, Lakshmi Pisharody, Syeda Tasneem Towhid, Élisabeth Mercier, Zhihao Zhang, Shen Wan, Ocean Thakali, Md Pervez Kabir, Alejandro Gronskis, 汪建来, F. H. Hilliard, Alex MacKenzie, Tyson E. Graber, 誠鈴木, Robert Delatolla	2023	1
5	Vorinostat Improves Myotonic Dystrophy Type 1 Splicing Abnormalities in DM1 Muscle Cell Lines and Skeletal Muscle from a DM1 Mouse Model International Journal of Molecular Sciences ·Nafisa Neault, Aymeric Ravel‐Chapuis, Stephen Baird, John A. Lunde, Kazunori Moriki, A. Dec, Julio Plaza‐Díaz, Gerardo Medina, Francisco Abadía‐Molina, Bernard J. Jasmin, Alex MacKenzie	2023	5
6	A Review of the Current Impact of Inhibitors of Apoptosis Proteins and Their Repression in Cancer Cancers ·Inti Macdalene Anto, Julio Plaza‐Díaz, Alex MacKenzie, Francisco Abadía‐Molina	2022	76
7	Separating the Wheat from the Chaff: The Use of Upstream Regulator Analysis to Identify True Differential Expression of Single Genes within Transcriptomic Datasets International Journal of Molecular Sciences ·伍雯璨, Sarah Schock, William F. Craft, Alex MacKenzie, Julio Plaza‐Díaz	2021	1
8	Autosomal dominant cutis laxa with progeroid features due to a novel, de novo mutation in ALDH18A1 Journal of Human Genetics ·Puja T. Pape, Taila Hartley, Eric Bareke, Kym M. Boycott, Alex MacKenzie, Jacek Majewski, Michael Brudno, Dennis E. Bulman, David A. Dyment, Sarah M. Nikkel	2017	11
9	The Canadian Neuromuscular Disease Registry: Connecting patients to national and international research opportunities Paediatrics & Child Health ·Ky Yong Choi, Anna McCormick, Alex MacKenzie, Erin O’Ferrall, Shannon L. Venance, Jean K. Mah, Kathryn Selby, Hugh J. McMillan, Chen Ruiyan, Maryam Oskoui, Luis Alonso Rondón Gómez, Laura McAdam, A. R. Haziiev, Victoria Hodgkinson, Tang Jiao, Lawrence Korngut, Craig Campbell	2017	11
10	Mouse lysine catabolism to aminoadipate occurs primarily through the saccharopine pathway; implications for pyridoxine dependent epilepsy (PDE) Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Izabella A. Pena, Lygia Azevedo Marques, Angelo B. A. Laranjeira, José Andrés Yunes, Marcos N. Eberlin, Alex MacKenzie, Paulo Arruda	2016	47
11	Sodium Channel Inhibitors Reduce DMPK mRNA and Protein Clinical and Translational Science ·Luke Witherspoon, W. C. Muller, 伍雯璨, В С Приходько, Alex MacKenzie, William F. Craft	2015	11
12	The study of drugs for rare disorders: harnessing research contributions by Canadian academic institutions. PubMed ·Stuart MacLeod, Paul Lasko, Alex MacKenzie	2014	2
13	Rare-disease genetics in the era of next-generation sequencing: discovery to translation Nature Reviews Genetics ·Kym M. Boycott, Megan R. Vanstone, Dennis E. Bulman, Alex MacKenzie Hit paper breakdown →	2013	496
14	Functional human NAIP promoter transcription regulatory elements for the NAIP and ΨNAIP genes Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·Ming Xu, Takeya Okada, Harumi Sakai, G. Vidyadharani, Yoshiko Yanagisawa, Alex MacKenzie, Shinji Hadano, Joh-E Ikeda	2002	12
15	The Neuronal Apoptosis Inhibitory Protein (Naip) Is Expressed in Macrophages and Is Modulated After Phagocytosis and During Intracellular Infection with Legionella pneumophila The Journal of Immunology ·Eduardo Diez, Zahra Yaraghi, Alex MacKenzie, Philippe Gros	2000	59
16	A small interstitial deletion in the GPC3 gene causes Simpson-Golabi-Behmel syndrome in a Dutch-Canadian family Journal of Medical Genetics ·Jian Ying Xuan, W. H. Thomin, Alex MacKenzie	1999	43
17	The inhibitors of apoptosis (IAPs) and their emerging role in cancer Oncogene ·Eric C. LaCasse, Stephen Baird, Robert G. Korneluk, Alex MacKenzie Hit paper breakdown →	1998	837
18	Life and death decisions: the role of the IAPs in modulating programmed cell death APOPTOSIS ·Peter Liston, S. S. Y. Young, Alex MacKenzie, Robert G. Korneluk	1997	50
19	Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome Nature Genetics ·Giuseppe Pilia, M. Bolt, Alex MacKenzie, Primo Baybayan, Ellson Y. Chen, Reid Huber, Giovanni Neri, Antonio Cao, Antonino Forabosco, David Schlessinger Hit paper breakdown →	1996	593
20	DNA Polymorphism and Linkage Disequilibrium within the Apolipoprotein CII Locus on Human Chromosome 19 Human Heredity ·Alex MacKenzie, Agnieszka Olechnicka, S. Leblond, AR Korabik, Guilherme de Castro Rezende, Robert G. Korneluk	1991	2

About Alex MacKenzie

Alex MacKenzie is a scholar working on Genetics, Molecular Biology, Clinical Biochemistry, Cellular and Molecular Neuroscience and Biochemistry, having authored 125 papers that have together received 6.8k indexed citations. Recurring topics across this work include Neurogenetic and Muscular Disorders Research (37 papers), RNA modifications and cancer (31 papers), Cell death mechanisms and regulation (19 papers), Mitochondrial Function and Pathology (15 papers), RNA Research and Splicing (15 papers), Congenital Anomalies and Fetal Surgery (13 papers), Genetic Neurodegenerative Diseases (11 papers) and SARS-CoV-2 detection and testing (10 papers). The work is most often cited by research in Genetics (739 citations), Molecular Biology (4.6k citations), Cellular and Molecular Neuroscience (784 citations), Cancer Research (588 citations) and Genetics (1.1k citations). Alex MacKenzie has collaborated with scholars based in Canada, United States and Spain. Frequent co-authors include Robert G. Korneluk, Stephen Baird, Eric C. LaCasse, Kym M. Boycott, Dennis E. Bulman, Megan R. Vanstone, Katsuyuki Tamai, Charles Lefebvre, Reza Mastery Farahani and Natalie Roy. Their work appears in journals such as Human Molecular Genetics, Genomics, Orphanet Journal of Rare Diseases, The Science of The Total Environment and Neurology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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