Alex MacKenzie

11.5k total citations · 4 hit papers
125 papers, 6.8k citations indexed

About

Alex MacKenzie is a scholar working on Molecular Biology, Genetics and Cellular and Molecular Neuroscience. According to data from OpenAlex, Alex MacKenzie has authored 125 papers receiving a total of 6.8k indexed citations (citations by other indexed papers that have themselves been cited), including 86 papers in Molecular Biology, 39 papers in Genetics and 16 papers in Cellular and Molecular Neuroscience. Recurrent topics in Alex MacKenzie's work include Neurogenetic and Muscular Disorders Research (37 papers), RNA modifications and cancer (31 papers) and Cell death mechanisms and regulation (19 papers). Alex MacKenzie is often cited by papers focused on Neurogenetic and Muscular Disorders Research (37 papers), RNA modifications and cancer (31 papers) and Cell death mechanisms and regulation (19 papers). Alex MacKenzie collaborates with scholars based in Canada, United States and Spain. Alex MacKenzie's co-authors include Robert G. Korneluk, Stephen Baird, Eric C. LaCasse, Kym M. Boycott, Dennis E. Bulman, Megan R. Vanstone, Katsuyuki Tamai, Charles Lefebvre, Reza Mastery Farahani and Natalie Roy and has published in prestigious journals such as Nature, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Alex MacKenzie

120 papers receiving 6.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1996 859 citations Stephen Baird, Alex MacKenzie et al. profile →
The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1998 837 citations Eric C. LaCasse, Stephen Baird et al. Oncogene profile →
Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome

1996 593 citations Giuseppe Pilia, Alex MacKenzie et al. Nature Genetics profile →
Rare-disease genetics in the era of next-generation sequencing: discovery to translation

2013 496 citations Kym M. Boycott, Megan R. Vanstone et al. Nature Reviews Genetics profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alex MacKenzie Canada	37	4.6k	1.1k	784	739	735	125	6.8k
Antonia Follenzi Italy	48	4.6k 1.0×	2.0k 1.9×	681 0.9×	762 1.0×	945 1.3×	156	8.9k
Naohiro Terada United States	49	6.5k 1.4×	710 0.7×	578 0.7×	1.3k 1.7×	1.3k 1.8×	158	9.7k
Sheila A. Stewart United States	46	6.6k 1.4×	827 0.8×	359 0.5×	379 0.5×	2.0k 2.7×	84	10.7k
Andrew D. Rouillard United States	12	4.9k 1.1×	743 0.7×	308 0.4×	219 0.3×	1.1k 1.5×	17	8.1k
Rui Zhao China	28	4.5k 1.0×	557 0.5×	292 0.4×	423 0.6×	214 0.3×	100	6.3k
Charles C. Hong United States	42	3.6k 0.8×	540 0.5×	419 0.5×	738 1.0×	540 0.7×	141	6.9k
Ivan Topisirović Canada	52	7.7k 1.7×	512 0.5×	301 0.4×	410 0.6×	1.0k 1.4×	111	9.6k
Maria Sibilia Austria	46	5.8k 1.2×	819 0.8×	647 0.8×	359 0.5×	1.8k 2.4×	117	10.1k
Sylvain Meloche Canada	54	7.3k 1.6×	507 0.5×	460 0.6×	333 0.5×	1.4k 2.0×	151	10.6k
Caroline D. Monteiro United States	6	4.5k 1.0×	713 0.7×	286 0.4×	205 0.3×	1.1k 1.4×	6	7.1k

Countries citing papers authored by Alex MacKenzie

Since Specialization

Citations

This map shows the geographic impact of Alex MacKenzie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alex MacKenzie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alex MacKenzie more than expected).

Fields of papers citing papers by Alex MacKenzie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alex MacKenzie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alex MacKenzie. The network helps show where Alex MacKenzie may publish in the future.

Co-authorship network of co-authors of Alex MacKenzie

This figure shows the co-authorship network connecting the top 25 collaborators of Alex MacKenzie. A scholar is included among the top collaborators of Alex MacKenzie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alex MacKenzie. Alex MacKenzie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Roda, Weston, Hugh J. McMillan, Maryam Oskoui, et al.. (2025). A cost-utility analysis of newborn screening for spinal muscular atrophy in Canada. Orphanet Journal of Rare Diseases. 20(1). 428–428.

Mercier, Élisabeth, Patrick M. D’Aoust, Nada Hegazy, et al.. (2024). Sewer transport conditions and their role in the decay of endogenous SARS-CoV-2 and pepper mild mottle virus from source to collection. International Journal of Hygiene and Environmental Health. 263. 114477–114477.

Mercier, Élisabeth, Patrick M. D’Aoust, Md Pervez Kabir, et al.. (2024). Urban wastewater contains a functional human antibody repertoire of mucosal origin. Water Research. 267. 122532–122532. 2 indexed citations

Hegazy, Nada, Xin Tian, Patrick M. D’Aoust, et al.. (2023). Impact of coagulation on SARS-CoV-2 and PMMoV viral signal in wastewater solids. Environmental Science and Pollution Research. 31(4). 5242–5253. 1 indexed citations

Neault, Nafisa, Aymeric Ravel‐Chapuis, Stephen Baird, et al.. (2023). Vorinostat Improves Myotonic Dystrophy Type 1 Splicing Abnormalities in DM1 Muscle Cell Lines and Skeletal Muscle from a DM1 Mouse Model. International Journal of Molecular Sciences. 24(4). 3794–3794. 5 indexed citations

Plaza‐Díaz, Julio, et al.. (2022). A Review of the Current Impact of Inhibitors of Apoptosis Proteins and Their Repression in Cancer. Cancers. 14(7). 1671–1671. 76 indexed citations

Schock, Sarah, et al.. (2021). Separating the Wheat from the Chaff: The Use of Upstream Regulator Analysis to Identify True Differential Expression of Single Genes within Transcriptomic Datasets. International Journal of Molecular Sciences. 22(12). 6295–6295. 1 indexed citations

Hartley, Taila, Eric Bareke, Kym M. Boycott, et al.. (2017). Autosomal dominant cutis laxa with progeroid features due to a novel, de novo mutation in ALDH18A1. Journal of Human Genetics. 62(6). 661–663. 11 indexed citations

McCormick, Anna, Alex MacKenzie, Erin O’Ferrall, et al.. (2017). The Canadian Neuromuscular Disease Registry: Connecting patients to national and international research opportunities. Paediatrics & Child Health. 23(1). 20–26. 11 indexed citations

10.

Pena, Izabella A., Lygia Azevedo Marques, Angelo B. A. Laranjeira, et al.. (2016). Mouse lysine catabolism to aminoadipate occurs primarily through the saccharopine pathway; implications for pyridoxine dependent epilepsy (PDE). Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863(1). 121–128. 47 indexed citations

11.

Witherspoon, Luke, et al.. (2015). Sodium Channel Inhibitors Reduce DMPK mRNA and Protein. Clinical and Translational Science. 8(4). 298–304. 11 indexed citations

12.

MacLeod, Stuart, Paul Lasko, & Alex MacKenzie. (2014). The study of drugs for rare disorders: harnessing research contributions by Canadian academic institutions.. PubMed. 21(1). e47–55. 2 indexed citations

13.

Boycott, Kym M., Megan R. Vanstone, Dennis E. Bulman, & Alex MacKenzie. (2013). Rare-disease genetics in the era of next-generation sequencing: discovery to translation. Nature Reviews Genetics. 14(10). 681–691. 496 indexed citations breakdown →

14.

Xu, Ming, Takeya Okada, Harumi Sakai, et al.. (2002). Functional human NAIP promoter transcription regulatory elements for the NAIP and ΨNAIP genes. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1574(1). 35–50. 12 indexed citations

15.

Diez, Eduardo, Zahra Yaraghi, Alex MacKenzie, & Philippe Gros. (2000). The Neuronal Apoptosis Inhibitory Protein (Naip) Is Expressed in Macrophages and Is Modulated After Phagocytosis and During Intracellular Infection with Legionella pneumophila. The Journal of Immunology. 164(3). 1470–1477. 59 indexed citations

16.

Xuan, Jian Ying, et al.. (1999). A small interstitial deletion in the GPC3 gene causes Simpson-Golabi-Behmel syndrome in a Dutch-Canadian family. Journal of Medical Genetics. 36(1). 57–58. 43 indexed citations

17.

LaCasse, Eric C., Stephen Baird, Robert G. Korneluk, & Alex MacKenzie. (1998). The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene. 17(25). 3247–3259. 837 indexed citations breakdown →

18.

Liston, Peter, S. S. Y. Young, Alex MacKenzie, & Robert G. Korneluk. (1997). Life and death decisions: the role of the IAPs in modulating programmed cell death. APOPTOSIS. 2(5). 423–441. 50 indexed citations

19.

Pilia, Giuseppe, Alex MacKenzie, Primo Baybayan, et al.. (1996). Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nature Genetics. 12(3). 241–247. 593 indexed citations breakdown →

20.

MacKenzie, Alex, et al.. (1991). DNA Polymorphism and Linkage Disequilibrium within the Apolipoprotein CII Locus on Human Chromosome 19. Human Heredity. 41(3). 188–194. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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