Eric C. LaCasse

6.4k total citations · 1 hit paper
65 papers, 5.2k citations indexed

About

Eric C. LaCasse is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, Eric C. LaCasse has authored 65 papers receiving a total of 5.2k indexed citations (citations by other indexed papers that have themselves been cited), including 49 papers in Molecular Biology, 23 papers in Immunology and 14 papers in Oncology. Recurrent topics in Eric C. LaCasse's work include Cell death mechanisms and regulation (33 papers), RNA Interference and Gene Delivery (12 papers) and interferon and immune responses (10 papers). Eric C. LaCasse is often cited by papers focused on Cell death mechanisms and regulation (33 papers), RNA Interference and Gene Delivery (12 papers) and interferon and immune responses (10 papers). Eric C. LaCasse collaborates with scholars based in Canada, United States and United Kingdom. Eric C. LaCasse's co-authors include Robert G. Korneluk, Stephen Baird, Alex MacKenzie, Herman H. Cheung, Allison M. Hunter, Douglas J. Mahoney, Stéphanie Plenchette, Yvonne A. Lefebvre, Jon P. Durkin and Shawn T. Beug and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

Eric C. LaCasse

65 papers receiving 5.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1998 837 citations Eric C. LaCasse, Stephen Baird et al. Oncogene profile →

Peers

Countries citing papers authored by Eric C. LaCasse

Since Specialization

Citations

This map shows the geographic impact of Eric C. LaCasse's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric C. LaCasse with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric C. LaCasse more than expected).

Fields of papers citing papers by Eric C. LaCasse

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric C. LaCasse. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric C. LaCasse. The network helps show where Eric C. LaCasse may publish in the future.

Co-authorship network of co-authors of Eric C. LaCasse

This figure shows the co-authorship network connecting the top 25 collaborators of Eric C. LaCasse. A scholar is included among the top collaborators of Eric C. LaCasse based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eric C. LaCasse. Eric C. LaCasse is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Cell death in glioblastoma and the central nervous system 2024 ·Cellular Oncology ·(unknown), Eric C. LaCasse, Shawn T. Beug	1
2	IAPs and RIPK1 mediate LPS-induced cytokine production in healthy subjects and Crohn’s disease 2023 ·Clinical & Experimental Immunology ·Jakob Benedict Seidelin, (unknown), Morten Hansen, (unknown), (unknown), Sergey Nejentsev, Eric C. LaCasse, Ole Haagen Nielsen	2
3	Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy 2019 ·Skeletal Muscle ·(unknown), (unknown), (unknown), (unknown), (unknown), Martine St-Jean, Eric C. LaCasse, Robert G. Korneluk	26
4	The transcription factor SP3 drives TNF-α expression in response to Smac mimetics 2019 ·Science Signaling ·Shawn T. Beug, Herman H. Cheung, (unknown), Martine St-Jean, (unknown), Hapsatou Mamady, Stephen Baird, Eric C. LaCasse, Robert G. Korneluk	12
5	Combinatorial cancer immunotherapy strategies with proapoptotic small-molecule IAP antagonists 2015 ·The International Journal of Developmental Biology ·Shawn T. Beug, (unknown), Tommy Alain, Robert G. Korneluk, Eric C. LaCasse	18
6	Inhibitors of apoptosis (IAPs) regulate intestinal immunity and inflammatory bowel disease (IBD) inflammation 2014 ·Trends in Molecular Medicine ·Jannie Pedersen, Eric C. LaCasse, Jakob Benedict Seidelin, Mehmet Coskun, Ole Haagen Nielsen	89
7	Modulation of immune signalling by inhibitors of apoptosis 2012 ·Trends in Immunology ·Shawn T. Beug, Herman H. Cheung, Eric C. LaCasse, Robert G. Korneluk	114
8	SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds 2011 ·Cell Death and Disease ·Herman H. Cheung, (unknown), Shawn T. Beug, (unknown), Eric C. LaCasse, Stephen Baird, David F. Stojdl, Robert A. Screaton, Robert G. Korneluk	24
9	Down-regulation of c-FLIP Enhances Death of Cancer Cells by Smac Mimetic Compound 2009 ·Cancer Research ·Herman H. Cheung, Douglas J. Mahoney, Eric C. LaCasse, Robert G. Korneluk	57
10	Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation 2008 ·Proceedings of the National Academy of Sciences ·Douglas J. Mahoney, Herman H. Cheung, (unknown), Stéphanie Plenchette, Carl Simard, Emeka K. Enwere, Vinay A. Arora, Tak W. Mak, Eric C. LaCasse, Jeffrey F. Waring, Robert G. Korneluk	426
11	X-linked Inhibitor of Apoptosis Regulates T Cell Effector Function 2007 ·The Journal of Immunology ·Simone P. Zehntner, Lyne Bourbonnière, Craig S. Moore, Stephen J. Morris, Danielle Méthot, (unknown), Eric C. LaCasse, Andrea L.O. Hebb, George S. Robertson, Jon P. Durkin, John W. Gillard, Trevor Owens	20
12	Downregulation of XIAP expression in ovarian cancer cells induces cell death in vitro and in vivo 2007 ·International Journal of Cancer ·Tanya J. Shaw, Eric C. LaCasse, Jon P. Durkin, Barbara C. Vanderhyden	48
13	AEG35156, a XIAP antisense oligonucleotide, suppresses XIAP levels in targeted tissues isolated from pre-clinical models and from patients 2006 ·Cancer Research ·Eric C. LaCasse, Stephen Morris, Tim Ward, (unknown), L Robson, (unknown), Danielle Méthot, Lori Jerome, P.D. Winocour, John W. Gillard, Jacques Jolivet, Duncan I. Jodrell, Malcolm Ranson, Jon P. Durkin	3
14	Method validation and preliminary qualification of pharmacodynamic biomarkers employed to evaluate the clinical efficacy of an antisense compound (AEG35156) targeted to the X-linked inhibitor of apoptosis protein XIAP 2006 ·British Journal of Cancer ·Jeffrey L. Cummings, Malcolm Ranson, Eric C. LaCasse, (unknown), Martine St-Jean, Gordon C. Jayson, J. P. Durkin, Caroline Dive	52
15	Spurious splicing within the XIAP 5′ UTR occurs in the Rluc/Fluc but not the βgal/CAT bicistronic reporter system 2005 ·RNA ·Martin Holčı́k, Tyson E. Graber, Stephen M. Lewis, Charles Lefebvre, Eric C. LaCasse, Stephen Baird	57
16	Application of XIAP Antisense to Cancer and Other Proliferative Disorders: Development of AEG35156/ GEM®640 2005 ·Annals of the New York Academy of Sciences ·Eric C. LaCasse, Ekambar R. Kandimalla, P.D. Winocour, Timothy J. Sullivan, Sudhir Agrawal, John W. Gillard, Jon P. Durkin	52
17	Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP 2005 ·British Journal of Cancer ·Jeffrey L. Cummings, Timothy H. Ward, Eric C. LaCasse, Charles Lefebvre, Martine St-Jean, J. P. Durkin, Malcolm Ranson, Caroline Dive	64
18	Marked Induction of the IAP Family Antiapoptotic Proteins Survivin and XIAP by VEGF in Vascular Endothelial Cells 1999 ·Biochemical and Biophysical Research Communications ·Jennifer M. Tran, Janusz Rak, (unknown), Samuel D. Saibil, Eric C. LaCasse, Robert G. Korneluk, Robert S. Kerbel	291
19	Recruitment of Octamer Transcription Factors to DNA by Glucocorticoid Receptor 1998 ·Molecular and Cellular Biology ·Gratien G. Préfontaine, Madeleine E. Lemieux, Ward Giffin, Caroline Schild‐Poulter, L. S. Pope, Eric C. LaCasse, Peter J. Walker, Robert J.G. Haché	80
20	The inhibitors of apoptosis (IAPs) and their emerging role in cancer breakdown → 1998 ·Oncogene ·Eric C. LaCasse, Stephen Baird, Robert G. Korneluk, Alex MacKenzie	837

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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