Lalage M. Wakefield

28.0k total citations · 14 hit papers
150 papers, 23.2k citations indexed

About

Lalage M. Wakefield is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Lalage M. Wakefield has authored 150 papers receiving a total of 23.2k indexed citations (citations by other indexed papers that have themselves been cited), including 110 papers in Molecular Biology, 69 papers in Oncology and 23 papers in Cancer Research. Recurrent topics in Lalage M. Wakefield's work include TGF-β signaling in diseases (78 papers), Cancer Cells and Metastasis (40 papers) and Genetic factors in colorectal cancer (19 papers). Lalage M. Wakefield is often cited by papers focused on TGF-β signaling in diseases (78 papers), Cancer Cells and Metastasis (40 papers) and Genetic factors in colorectal cancer (19 papers). Lalage M. Wakefield collaborates with scholars based in United States, United Kingdom and Japan. Lalage M. Wakefield's co-authors include Michael B. Sporn, Anita B. Roberts, John H. Kehrl, Richard K. Assoian, N S Roche, Kathleen C. Flanders, Sonia B. Jakowlew, Benoît De Crombrugghe, Rik Derynck and Ursula Heine and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Lalage M. Wakefield

148 papers receiving 22.5k citations

Hit Papers

Transforming growth factor type beta: rapid induction of ... 1985 2026 1998 2012 1986 1986 1987 1987 1986 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.
    1986 2.4k citations Lalage M. Wakefield, John H. Kehrl et al. Proceedings of the National Academy of Sciences profile →
  2. Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.
    1986 1.4k citations John H. Kehrl, Lalage M. Wakefield et al. The Journal of Experimental Medicine profile →
  3. Some recent advances in the chemistry and biology of transforming growth factor-beta.
    1987 1.1k citations Lalage M. Wakefield et al. profile →
  4. Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.
    1987 1.1k citations Lalage M. Wakefield et al. Proceedings of the National Academy of Sciences profile →
  5. Transforming Growth Factor-β: Biological Function and Chemical Structure
    1986 1.0k citations Lalage M. Wakefield et al. profile →
  6. Type beta transforming growth factor: a bifunctional regulator of cellular growth.
    1985 972 citations Lalage M. Wakefield et al. Proceedings of the National Academy of Sciences profile →
  7. Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells
    1987 811 citations Lalage M. Wakefield, Kathleen C. Flanders et al. profile →
  8. TGF-β signaling: positive and negative effects on tumorigenesis
    2002 692 citations Lalage M. Wakefield profile →
  9. Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.
    1986 652 citations John H. Kehrl, Lalage M. Wakefield et al. profile →
  10. The two faces of transforming growth factor β in carcinogenesis
    2003 607 citations Lalage M. Wakefield et al. Proceedings of the National Academy of Sciences profile →
  11. Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.
    1995 559 citations Lalage M. Wakefield et al. Proceedings of the National Academy of Sciences profile →
  12. Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells.
    1986 495 citations Lalage M. Wakefield et al. Proceedings of the National Academy of Sciences profile →
  13. Distribution and modulation of the cellular receptor for transforming growth factor-beta.
    1987 488 citations Lalage M. Wakefield et al. profile →
  14. Latent transforming growth factor-beta from human platelets. A high molecular weight complex containing precursor sequences.
    1988 477 citations Lalage M. Wakefield, Kathleen C. Flanders et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Lalage M. Wakefield United States 64 13.6k 6.9k 3.3k 3.3k 2.5k 150 23.2k
James D. Griffin United States 95 12.8k 0.9× 7.4k 1.1× 5.3k 1.6× 1.9k 0.6× 1.5k 0.6× 354 29.7k
Masabumi Shibuya Japan 68 12.6k 0.9× 4.8k 0.7× 2.7k 0.8× 3.8k 1.2× 1.4k 0.6× 215 20.7k
Lawrence F. Brown United States 75 13.7k 1.0× 6.1k 0.9× 2.7k 0.8× 5.2k 1.6× 992 0.4× 111 23.2k
Malcolm A.S. Moore United States 82 13.2k 1.0× 7.6k 1.1× 7.4k 2.3× 3.2k 1.0× 2.7k 1.1× 337 28.5k
Michael Zeisberg Germany 55 10.6k 0.8× 5.6k 0.8× 2.1k 0.7× 3.6k 1.1× 1.4k 0.6× 105 21.1k
Rolf A. Brekken United States 73 9.3k 0.7× 6.4k 0.9× 3.5k 1.1× 4.4k 1.4× 1.3k 0.5× 271 19.5k
Dylan R. Edwards United Kingdom 82 9.5k 0.7× 6.2k 0.9× 2.8k 0.9× 9.1k 2.8× 1.4k 0.6× 233 22.9k
Hans‐Peter Gerber United States 51 12.1k 0.9× 5.7k 0.8× 2.2k 0.7× 4.6k 1.4× 1.2k 0.5× 91 21.1k
William Vainchenker France 91 11.9k 0.9× 3.8k 0.5× 4.9k 1.5× 1.3k 0.4× 2.2k 0.9× 569 29.2k
Gavin Thurston United States 63 13.8k 1.0× 5.5k 0.8× 2.3k 0.7× 4.1k 1.3× 758 0.3× 168 22.1k

Countries citing papers authored by Lalage M. Wakefield

Since Specialization
Citations

This map shows the geographic impact of Lalage M. Wakefield's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lalage M. Wakefield with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lalage M. Wakefield more than expected).

Fields of papers citing papers by Lalage M. Wakefield

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lalage M. Wakefield. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lalage M. Wakefield. The network helps show where Lalage M. Wakefield may publish in the future.

Co-authorship network of co-authors of Lalage M. Wakefield

This figure shows the co-authorship network connecting the top 25 collaborators of Lalage M. Wakefield. A scholar is included among the top collaborators of Lalage M. Wakefield based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lalage M. Wakefield. Lalage M. Wakefield is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Jiang, Peng, Yu Zhang, Beibei Ru, et al.. (2021). Systematic investigation of cytokine signaling activity at the tissue and single-cell levels. Nature Methods. 18(10). 1181–1191. 115 indexed citations
2.
Domínguez, Humberto de Jesús Ochoa, Binwu Tang, Howard H. Yang, et al.. (2020). Peptidylarginine Deiminase IV Regulates Breast Cancer Stem Cells via a Novel Tumor Cell–Autonomous Suppressor Role. Cancer Research. 80(11). 2125–2137. 20 indexed citations
3.
Yang, Yu-an, Howard H. Yang, Binwu Tang, et al.. (2019). The Outcome of TGFβ Antagonism in Metastatic Breast Cancer Models In Vivo Reflects a Complex Balance between Tumor-Suppressive and Proprogression Activities of TGFβ. Clinical Cancer Research. 26(3). 643–656. 20 indexed citations
4.
He, Chenxia, Jeanne M. Danes, Peter C. Hart, et al.. (2019). SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer. Proceedings of the National Academy of Sciences. 116(47). 23534–23541. 54 indexed citations
5.
Jones, Matthew F., Megha Subramanian, Svetlana A. Shabalina, et al.. (2015). Growth differentiation factor-15 encodes a novel microRNA 3189 that functions as a potent regulator of cell death. Cell Death and Differentiation. 22(10). 1641–1653. 27 indexed citations
6.
Bae, Eunjin, Misako Sato, Ran‐Ju Kim, et al.. (2014). Definition of Smad3 Phosphorylation Events That Affect Malignant and Metastatic Behaviors in Breast Cancer Cells. Cancer Research. 74(21). 6139–6149. 29 indexed citations
7.
Kohn, Ethan A., Yu-an Yang, Zhijun Du, et al.. (2012). Biological Responses to TGF-β in the Mammary Epithelium Show a Complex Dependency on Smad3 Gene Dosage with Important Implications for Tumor Progression. Molecular Cancer Research. 10(10). 1389–1399. 20 indexed citations
8.
Bian, Yansong, Anita Terse, Juan Du, et al.. (2009). Progressive Tumor Formation in Mice with Conditional Deletion of TGF-β Signaling in Head and Neck Epithelia Is Associated with Activation of the PI3K/Akt Pathway. Cancer Research. 69(14). 5918–5926. 75 indexed citations
9.
Kadota, Mitsutaka, Misako Sato, Akira Ooshima, et al.. (2009). Identification of Novel Gene Amplifications in Breast Cancer and Coexistence of Gene Amplification with an Activating Mutation of PIK3CA. Cancer Research. 69(18). 7357–7365. 97 indexed citations
10.
Nam, Jeong‐Seok, Masaki Terabe, Mizuko Mamura, et al.. (2008). An Anti–Transforming Growth Factor β Antibody Suppresses Metastasis via Cooperative Effects on Multiple Cell Compartments. Cancer Research. 68(10). 3835–3843. 187 indexed citations
11.
Nam, Jeong‐Seok, Masaki Terabe, Mi‐Jin Kang, et al.. (2008). Transforming Growth Factor β Subverts the Immune System into Directly Promoting Tumor Growth through Interleukin-17. Cancer Research. 68(10). 3915–3923. 198 indexed citations
12.
13.
Nam, Jeong‐Seok, Mi‐Jin Kang, Christina H. Stuelten, et al.. (2006). Bone Sialoprotein Mediates the Tumor Cell–Targeted Prometastatic Activity of Transforming Growth Factor β in a Mouse Model of Breast Cancer. Cancer Research. 66(12). 6327–6335. 72 indexed citations
14.
Nam, Jeong‐Seok, Mi‐Jin Kang, Takeshi Shimamura, et al.. (2006). Chemokine (C-C Motif) Ligand 2 Mediates the Prometastatic Effect of Dysadherin in Human Breast Cancer Cells. Cancer Research. 66(14). 7176–7184. 89 indexed citations
15.
Nam, Jeong‐Seok, et al.. (2004). Significance of dysadherin expression in breast cancer metastasis. Cancer Research. 64. 1163–1163.
16.
Ewan, Kenneth, G. Shyamala, Shraddha A. Ravani, et al.. (2002). Latent TGF-Beta activation in mammary gland: Regulation by ovarian hormones affects ductal and alveolar proliferation. The Journal of Pathology and Bacteriology. 160(6). 10 indexed citations
17.
Yang, Yu-an, Oksana I. Dukhanina, Binwu Tang, et al.. (2002). Lifetime exposure to a soluble TGF-β antagonist protects mice against metastasis without adverse side effects. Journal of Clinical Investigation. 109(12). 1607–1615. 278 indexed citations
18.
Ramakrishna, Gayatri, Bhalchandra A. Diwan, Yih‐Horng Shiao, et al.. (2001). Heterozygous inactivation of TGF-β1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras. Toxicology Letters. 123(2-3). 151–158. 7 indexed citations
19.
Kehrl, John H., Lalage M. Wakefield, Anita B. Roberts, et al.. (1986). Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.. The Journal of Experimental Medicine. 163(5). 1037–1050. 1378 indexed citations breakdown →
20.
Wakefield, Lalage M., et al.. (1971). Several factors affecting college coeds' food preferences, habits, and intake.. Journal of home economics. 63. 45–47. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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