Standout Papers

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel elec... 1975 2026 1992 2009 5.3k
  1. Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. (1977)
    Don W. Cleveland, S G Fischer et al. Journal of Biological Chemistry
  2. Dynamic instability of microtubule growth (1984)
    Tim Mitchison, Marc W. Kirschner Nature
  3. A protein factor essential for microtubule assembly. (1975)
    Arthur H. Lockwood, S Y Hwo et al. Proceedings of the National Academy of Sciences
  4. Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells (2015)
    Allon M. Klein, Linas Mažutis et al. Cell
  5. Cyclin is degraded by the ubiquitin pathway (1991)
    Michael Glotzer, Andrew W. Murray et al. Nature
  6. Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes (1980)
    Don W. Cleveland, Margaret A. Lopata et al. Cell
  7. A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage (1982)
    John W. Newport, Marc W. Kirschner Cell
  8. Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS (2003)
    Scott A. Gerber, A. John Rush et al. Proceedings of the National Academy of Sciences
  9. The Interaction between N-WASP and the Arp2/3 Complex Links Cdc42-Dependent Signals to Actin Assembly (1999)
    Rajat Rohatgi, Le Ma et al. Cell
  10. How Proteolysis Drives the Cell Cycle (1996)
    Randall W. King, Raymond J. Deshaies et al. Science
  11. Beyond self-assembly: From microtubules to morphogenesis (1986)
    Marc W. Kirschner Cell
  12. Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation (2012)
    Mohit Jain, Roland Nilsson et al. Science
  13. Cyclin synthesis drives the early embryonic cell cycle (1989)
    Andrew W. Murray, Marc W. Kirschner Nature
  14. Caspase-3-Generated Fragment of Gelsolin: Effector of Morphological Change in Apoptosis (1997)
    Srinivas Kothakota, Toshifumi Azuma et al. Science
  15. Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos (1991)
    Enrique Amaya, Thomas J. Musci et al. Cell
  16. The role of cyclin synthesis and degradation in the control of maturation promoting factor activity (1989)
    Andrew W. Murray, Mark J. Solomon et al. Nature
  17. A major developmental transition in early xenopus embryos: II. control of the onset of transcription (1982)
    John W. Newport, Marc W. Kirschner Cell
  18. A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B (1995)
    Randall W. King, Jan‐Michael Peters et al. Cell
  19. Evolvability (1998)
    Marc W. Kirschner, John C. Gerhart Proceedings of the National Academy of Sciences
  20. Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early xenopus embryo (1987)
    David Kimelman, Marc W. Kirschner Cell
  21. Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. (1992)
    David Drechsel, Anthony A. Hyman et al. Molecular Biology of the Cell
  22. cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2 (1991)
    Jean Gautier, Robert N. Booher et al. Cell
  23. Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin (1977)
    Don W. Cleveland, S Y Hwo et al. Journal of Molecular Biology
  24. Geminin, an Inhibitor of DNA Replication, Is Degraded during Mitosis (1998)
    Thomas J. McGarry, Marc W. Kirschner Cell
  25. Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins (1986)
    Frank McKeon, Marc W. Kirschner et al. Nature
  26. Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly (1977)
    Don W. Cleveland, S Y Hwo et al. Journal of Molecular Biology
  27. Cytoskeletal dynamics and nerve growth (1988)
    Tim Mitchison, Marc W. Kirschner Neuron
  28. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner (2012)
    Huai-Xiang Hao, Yang Xie et al. Nature
  29. Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. (1996)
    Orna Cohen‐Fix, Jan‐Michael Peters et al. Genes & Development
  30. Identification of a Vertebrate Sister-Chromatid Separation Inhibitor Involved in Transformation and Tumorigenesis (1999)
    Hui Zou, Thomas J. McGarry et al. Science
  31. Sequence-Specific and Phosphorylation-Dependent Proline Isomerization: A Potential Mitotic Regulatory Mechanism (1997)
    Michael B. Yaffe, Mike Schutkowski et al. Science
  32. Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck (2002)
    Sharon Eden, Rajat Rohatgi et al. Nature
  33. Microtubule assembly nucleated by isolated centrosomes (1984)
    Tim Mitchison, Marc W. Kirschner Nature
  34. Mitosis in transition (1994)
    Randall W. King, Peter K. Jackson et al. Cell
  35. Cyclin activation of p34cdc2 (1990)
    Michael Glotzer, Tina H. Lee et al. Cell
  36. Tau protein function in living cells. (1986)
    David G. Drubin, Marc W. Kirschner The Journal of Cell Biology
  37. Dominoes and Clocks: the Union of Two Views of the Cell Cycle (1989)
    Andrew W. Murray, Marc W. Kirschner Science
  38. The Primary Structure and Heterogeneity of Tau Protein from Mouse Brain (1988)
    Gloria Lee, Nicholas J. Cowan et al. Science
  39. mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2 (1991)
    Karen Lundgren, Nancy C. Walworth et al. Cell
  40. The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1 (2000)
    Cathie M. Pfleger, Marc W. Kirschner Genes & Development
  41. Filament organization revealed in platinum replicas of freeze-dried cytoskeletons. (1980)
    John E. Heuser, Marc W. Kirschner The Journal of Cell Biology
  42. The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway (2003)
    Ethan Lee, Adrian Salic et al. PLoS Biology
  43. Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs. (1984)
    John C. Gerhart, Michelle Wu et al. The Journal of Cell Biology
  44. γ-Tubulin is a highly conserved component of the centrosome (1991)
    Tim Stearns, Louise Evans et al. Cell
  45. Mechanism of N-Wasp Activation by Cdc42 and Phosphatidylinositol 4,5-Bisphosphate (2000)
    Rajat Rohatgi, Hsin‐Yi Henry Ho et al. The Journal of Cell Biology
  46. The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation (1998)
    Guowei Fang, Hongtao Yu et al. Genes & Development
  47. Rescuing US biomedical research from its systemic flaws (2014)
    Bruce Alberts, Marc W. Kirschner et al. Proceedings of the National Academy of Sciences
  48. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex (2004)
    Wenyi Wei, Nagi G. Ayad et al. Nature
  49. The dynamics of gene expression in vertebrate embryogenesis at single-cell resolution (2018)
    James Briggs, Caleb Weinreb et al. Science

Immediate Impact

154 by Nobel laureates 89 from Science/Nature 191 standout
Sub-graph 1 of 15

Citing Papers

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
30 intermediate papers

Works of Marc W. Kirschner being referenced

Tau Consists of a Set of Proteins with Repeated C-Terminal Microtubule-Binding Domains and Variable N-Terminal Domains
1989
Dynamic instability of microtubule growth
1984 StandoutNature
and 30 more

Author Peers

Author Last Decade Papers Cites
Marc W. Kirschner 65149 37465 10447 394 88.4k
John R. Yates 77427 17203 7151 987 107.2k
Philip Cohen 67060 13461 9697 488 88.5k
Tony Hunter 77156 17369 23136 502 103.0k
Steven P. Gygi 87120 17827 12298 689 119.3k
Kai Simons 57517 28458 3141 413 81.5k
Ruedi Aebersold 85496 9708 8964 776 115.8k
David M. Sabatini 70566 13245 9434 253 98.9k
Paul Tempst 61550 8629 8205 320 79.9k
Randy J. Read 61595 7817 6818 196 85.8k
Tony Pawson 49380 13014 10872 446 67.8k

All Works

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