Yves Ducharme

1.8k total citations
33 papers, 1.2k citations indexed

About

Yves Ducharme is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, Yves Ducharme has authored 33 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 13 papers in Organic Chemistry and 13 papers in Pharmacology. Recurrent topics in Yves Ducharme's work include Inflammatory mediators and NSAID effects (7 papers), Phosphodiesterase function and regulation (7 papers) and Cholinesterase and Neurodegenerative Diseases (6 papers). Yves Ducharme is often cited by papers focused on Inflammatory mediators and NSAID effects (7 papers), Phosphodiesterase function and regulation (7 papers) and Cholinesterase and Neurodegenerative Diseases (6 papers). Yves Ducharme collaborates with scholars based in Canada and United States. Yves Ducharme's co-authors include James D. Wuest, Richard W. Friesen, Christine Brideau, Zheng Huang, Bernard Côté, Dwight Macdonald, Denis Riendeau, Annette Robichaud, Daigen Xu and Joseph A. Mancini and has published in prestigious journals such as Journal of the American Chemical Society, Analytical Chemistry and Journal of Medicinal Chemistry.

In The Last Decade

Yves Ducharme

32 papers receiving 1.2k citations

Peers

Yves Ducharme
Elizabeth A. Lunney United States
Yvan Guindon Canada
Jay Wrobel United States
Mario Cardozo United States
Johannes C. Hermann United States
Jay R. Luly United States
Junmin Quan China
Christine Luong United States
Soo S. Ko United States
Alexandra Hamacher Germany
Elizabeth A. Lunney United States
Yves Ducharme
Citations per year, relative to Yves Ducharme Yves Ducharme (= 1×) peers Elizabeth A. Lunney

Countries citing papers authored by Yves Ducharme

Since Specialization
Citations

This map shows the geographic impact of Yves Ducharme's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yves Ducharme with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yves Ducharme more than expected).

Fields of papers citing papers by Yves Ducharme

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yves Ducharme. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yves Ducharme. The network helps show where Yves Ducharme may publish in the future.

Co-authorship network of co-authors of Yves Ducharme

This figure shows the co-authorship network connecting the top 25 collaborators of Yves Ducharme. A scholar is included among the top collaborators of Yves Ducharme based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yves Ducharme. Yves Ducharme is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Cauchon, Elizabeth, Austin Chen, Amandine Chefson, et al.. (2012). Design and synthesis of potent, isoxazole-containing renin inhibitors. Bioorganic & Medicinal Chemistry Letters. 22(8). 2670–2674. 9 indexed citations
2.
Boulet, Louise, Christine Brideau, David Claveau, et al.. (2011). Trisubstituted ureas as potent and selective mPGES-1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 21(5). 1488–1492. 22 indexed citations
3.
Lévesque, Jean-François, Kelly Bleasby, Amandine Chefson, et al.. (2011). Impact of passive permeability and gut efflux transport on the oral bioavailability of novel series of piperidine-based renin inhibitors in rodents. Bioorganic & Medicinal Chemistry Letters. 21(18). 5547–5551. 9 indexed citations
4.
Chen, Austin, Renée Aspiotis, Louis‐Charles Campeau, et al.. (2011). Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of spirocyclic piperidines. Bioorganic & Medicinal Chemistry Letters. 21(24). 7399–7404. 11 indexed citations
5.
Colucci, John, Michael J. Boyd, Carl Berthelette, et al.. (2010). Discovery of 4-{1-[({1-[4-(trifluoromethyl)benzyl]-1H-indol-7-yl}carbonyl)amino]cyclopropyl}benzoic acid (MF-766), a highly potent and selective EP4 antagonist for treating inflammatory pain. Bioorganic & Medicinal Chemistry Letters. 20(12). 3760–3763. 29 indexed citations
6.
Wu, Tom, Hélène Jûteau, Yves Ducharme, et al.. (2010). Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1. Bioorganic & Medicinal Chemistry Letters. 20(23). 6978–6982. 29 indexed citations
7.
Burch, Jason D., John Colucci, Claudio F. Sturino, et al.. (2010). Naphthalene/quinoline amides and sulfonylureas as potent and selective antagonists of the EP4 receptor. Bioorganic & Medicinal Chemistry Letters. 21(3). 1041–1046. 12 indexed citations
8.
Xu, Daigen, Patsy Clark, André Giroux, et al.. (2008). MF63 [2-(6-Chloro-1 H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a Selective Microsomal Prostaglandin E Synthase-1 Inhibitor, Relieves Pyresis and Pain in Preclinical Models of Inflammation. Journal of Pharmacology and Experimental Therapeutics. 326(3). 754–763. 129 indexed citations
9.
Côté, Bernard, Louise Boulet, Christine Brideau, et al.. (2007). Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(24). 6816–6820. 116 indexed citations
10.
Clark, Patsy, Robert J. Gordon, Jocelyne Guay, et al.. (2007). Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic, [3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone], in multiple preclinical species. European Journal of Pharmacology. 560(2-3). 216–224. 12 indexed citations
11.
Grimm, Erich L., Christine Brideau, Nathalie Chauret, et al.. (2006). Substituted coumarins as potent 5-lipoxygenase inhibitors. Bioorganic & Medicinal Chemistry Letters. 16(9). 2528–2531. 44 indexed citations
12.
Mathieu, Marie‐Claude, Nicole Sawyer, Gillian Greig, et al.. (2005). The C3a receptor antagonist SB 290157 has agonist activity. Immunology Letters. 100(2). 139–145. 72 indexed citations
13.
Côté, Bernard, Richard Frenette, Marc Blouin, et al.. (2003). Substituted aminopyridines as potent and selective phosphodiesterase-4 inhibitors. Bioorganic & Medicinal Chemistry Letters. 13(4). 741–744. 7 indexed citations
14.
Ducharme, Yves, Richard W. Friesen, Marc Blouin, et al.. (2003). Substituted 2-Pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors. Bioorganic & Medicinal Chemistry Letters. 13(11). 1923–1926. 12 indexed citations
15.
Chauret, Nathalie, Daniel Guay, Chun Li, et al.. (2002). Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding. Bioorganic & Medicinal Chemistry Letters. 12(16). 2149–2152. 54 indexed citations
16.
Frenette, Richard, Marc Blouin, Christine Brideau, et al.. (2002). Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters. Bioorganic & Medicinal Chemistry Letters. 12(20). 3009–3013. 20 indexed citations
17.
Guay, Daniel, Pierre Hamel, Marc Blouin, et al.. (2002). Discovery of L-791,943: A potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor. Bioorganic & Medicinal Chemistry Letters. 12(11). 1457–1461. 45 indexed citations
18.
Huang, Zheng, Yves Ducharme, Dwight Macdonald, & Annette Robichaud. (2001). The next generation of PDE4 inhibitors. Current Opinion in Chemical Biology. 5(4). 432–438. 100 indexed citations
19.
Chun, Li, Nathalie Chauret, Yves Ducharme, et al.. (1995). Integrated Application of Capillary HPLC/Continuous-Flow Liquid Secondary Ion Mass Spectrometry to Discovery Stage Metabolism Studies. Analytical Chemistry. 67(17). 2931–2936. 9 indexed citations
20.
Ducharme, Yves, Christine Brideau, Daniel Dubé, et al.. (1994). Naphthalenic Lignan Lactones as Selective, Nonredox 5-Lipoxygenase Inhibitors. Synthesis and Biological Activity of (Methoxyalkyl)thiazole and Methoxytetrahydropyran Hybrids. Journal of Medicinal Chemistry. 37(4). 512–518. 31 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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