Yves Ducharme

1.8k citations

33 papers · 1.2k indexed · h-index 18

Co-authors: James D. Wuest Richard W. Friesen Christine Brideau Zheng Huang Bernard Côté Dwight Macdonald Denis Riendeau Annette Robichaud
Topics: Inflammatory mediators and NSAID effects (7 papers)Phosphodiesterase function and regulation (7 papers)Cholinesterase and Neurodegenerative Diseases (6 papers)
Cited by: Pharmacology Organic Chemistry Virology
Journals: Journal of the American Chemical Society Analytical Chemistry Journal of Medicinal Chemistry
Partner nations: Canada United States

In The Last Decade

Yves Ducharme

32 papers receiving 1.2k citations

Peers

Countries citing papers authored by Yves Ducharme

Since Specialization

Citations

This map shows the geographic impact of Yves Ducharme's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yves Ducharme with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yves Ducharme more than expected).

Fields of papers citing papers by Yves Ducharme

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yves Ducharme. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yves Ducharme. The network helps show where Yves Ducharme may publish in the future.

Co-authorship network of co-authors of Yves Ducharme

This figure shows the co-authorship network connecting the top 25 collaborators of Yves Ducharme. A scholar is included among the top collaborators of Yves Ducharme based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yves Ducharme. Yves Ducharme is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Design and synthesis of potent, isoxazole-containing renin inhibitors 2012 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),(unknown),Elizabeth Cauchon,Austin Chen,Amandine Chefson,Yves Ducharme,Jean‐Pierre Falgueyret,Sébastien Gagné,Erich L. Grimm,Yongxin Han,Robert Houle,(unknown),Jean-François Lévesque,Dwight Macdonald,Bruce Mackay,(unknown),M. David Percival,Yeeman K. Ramtohul,(unknown),Sylvie Toulmond	9
2	Trisubstituted ureas as potent and selective mPGES-1 inhibitors 2011 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Louise Boulet,Christine Brideau,(unknown),David Claveau,Bernard Côté,Diane Ethier,André Giroux,Jocelyne Guay,Sébastien Guiral,Joseph A. Mancini,Frédéric Massé,Nathalie Méthot,Denis Riendeau,Patrick Roy,Joel Rubin,Daigen Xu,(unknown),Yves Ducharme,Richard W. Friesen	22
3	Impact of passive permeability and gut efflux transport on the oral bioavailability of novel series of piperidine-based renin inhibitors in rodents 2011 ·Bioorganic & Medicinal Chemistry Letters ·Jean-François Lévesque,Kelly Bleasby,Amandine Chefson,Austin Chen,Daniel Dubé,Yves Ducharme,(unknown),Sébastien Gagné,Michel Gallant,Erich L. Grimm,Michael J. Hafey,Yongxin Han,Robert Houle,(unknown),(unknown),Dwight Macdonald,Bruce Mackay,Robert Papp,Richard A. Tschirret-Guth	9
4	Renin inhibitors for the treatment of hypertension: Design and optimization of a novel series of spirocyclic piperidines 2011 ·Bioorganic & Medicinal Chemistry Letters ·Austin Chen,Renée Aspiotis,Louis‐Charles Campeau,Elizabeth Cauchon,(unknown),Yves Ducharme,Jean‐Pierre Falgueyret,Sébastien Gagné,Yongxin Han,Robert Houle,(unknown),(unknown),Jean-François Lévesque,(unknown),D. Percival	11
5	Discovery of 4-{1-[({1-[4-(trifluoromethyl)benzyl]-1H-indol-7-yl}carbonyl)amino]cyclopropyl}benzoic acid (MF-766), a highly potent and selective EP4 antagonist for treating inflammatory pain 2010 ·Bioorganic & Medicinal Chemistry Letters ·John Colucci,Michael J. Boyd,Carl Berthelette,(unknown),Zhaoyin Wang,Yves Ducharme,(unknown),Mark Wrona,Jean-François Lévesque,Danielle Denis,Marie‐Claude Mathieu,Rino Stocco,Alex G. Therien,(unknown),Steve Rowland,Daigen Xu,Yongxin Han	29
6	Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1 2010 ·Bioorganic & Medicinal Chemistry Letters ·Tom Wu,Hélène Jûteau,Yves Ducharme,Richard W. Friesen,Sébastien Guiral,(unknown),(unknown),Myriam Salem,Denis Riendeau,Joseph A. Mancini,Christine Brideau	29
7	Naphthalene/quinoline amides and sulfonylureas as potent and selective antagonists of the EP4 receptor 2010 ·Bioorganic & Medicinal Chemistry Letters ·Jason D. Burch,(unknown),John Colucci,Claudio F. Sturino,Yves Ducharme,Richard W. Friesen,Jean-François Lévesque,Sébastien Gagné,Mark Wrona,Alex G. Therien,Marie‐Claude Mathieu,Danielle Denis,Érika Vigneault,Daigen Xu,Patsy Clark,Steve Rowland,Yongxin Han	12
8	MF63 [2-(6-Chloro-1 H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a Selective Microsomal Prostaglandin E Synthase-1 Inhibitor, Relieves Pyresis and Pain in Preclinical Models of Inflammation 2008 ·Journal of Pharmacology and Experimental Therapeutics ·Daigen Xu,(unknown),Patsy Clark,André Giroux,Bernard Côté,Sébastien Guiral,Myriam Salem,Yves Ducharme,Richard W. Friesen,Nathalie Méthot,Joseph A. Mancini,Laurent Audoly,Denis Riendeau	129
9	Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors 2007 ·Bioorganic & Medicinal Chemistry Letters ·Bernard Côté,Louise Boulet,Christine Brideau,David Claveau,Diane Ethier,Richard Frenette,Marc Gagnon,André Giroux,Jocelyne Guay,Sébastien Guiral,Joseph A. Mancini,(unknown),Frédéric Massé,Nathalie Méthot,Denis Riendeau,Joel Rubin,Daigen Xu,(unknown),Yves Ducharme,Richard W. Friesen	116
10	Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic, [3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone], in multiple preclinical species 2007 ·European Journal of Pharmacology ·(unknown),Patsy Clark,Robert J. Gordon,(unknown),Jocelyne Guay,(unknown),Christine Brideau,Bernard Côté,Yves Ducharme,Joseph A. Mancini,Chi‐Chung Chan,Laurent Audoly,Daigen Xu	12
11	Substituted coumarins as potent 5-lipoxygenase inhibitors 2006 ·Bioorganic & Medicinal Chemistry Letters ·Erich L. Grimm,Christine Brideau,Nathalie Chauret,Chi‐Chung Chan,Daniel Delorme,Yves Ducharme,Diane Ethier,Jean‐Pierre Falgueyret,Richard W. Friesen,Jocelyne Guay,Pierre Hamel,Denis Riendeau,Chantal Soucy‐Breau,Philip Tagari,Yves Girard	44
12	The C3a receptor antagonist SB 290157 has agonist activity 2005 ·Immunology Letters ·Marie‐Claude Mathieu,Nicole Sawyer,Gillian Greig,Martine Hamel,Stacia Kargman,Yves Ducharme,Cheuk K. Lau,Richard W. Friesen,Gary P. O’Neill,François G. Gervais,Alex G. Therien	72
13	Substituted aminopyridines as potent and selective phosphodiesterase-4 inhibitors 2003 ·Bioorganic & Medicinal Chemistry Letters ·Bernard Côté,Richard Frenette,(unknown),Marc Blouin,Christine Brideau,Yves Ducharme,Richard W. Friesen,France Laliberté,P. Masson,Angela Styhler,Yves Girard	7
14	Substituted 2-Pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors 2003 ·Bioorganic & Medicinal Chemistry Letters ·Yves Ducharme,Richard W. Friesen,Marc Blouin,Bernard Côté,Daniel Dubé,Diane Ethier,Richard Frenette,France Laliberté,Joseph A. Mancini,P. Masson,Angela Styhler,Robert N. Young,Yves Girard	12
15	Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding 2002 ·Bioorganic & Medicinal Chemistry Letters ·Nathalie Chauret,Daniel Guay,Chun Li,Stephen H. Day,José Silva,Marc Blouin,Yves Ducharme,James A. Yergey,Deborah A. Nicoll‐Griffith	54
16	Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters 2002 ·Bioorganic & Medicinal Chemistry Letters ·Richard Frenette,Marc Blouin,Christine Brideau,Nathalie Chauret,Yves Ducharme,Richard W. Friesen,Pierre Hamel,Tom R. Jones,France Laliberté,Chun Li,P. Masson,M. McAuliffe,Yves Girard	20
17	Discovery of L-791,943: A potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor 2002 ·Bioorganic & Medicinal Chemistry Letters ·Daniel Guay,Pierre Hamel,Marc Blouin,Christine Brideau,Chi Chung Chan,Nathalie Chauret,Yves Ducharme,Zheng Huang,(unknown),Tom R. Jones,France Laliberté,P. Masson,M. McAuliffe,H. Piechuta,José Silva,Robert N. Young,Yves Girard	45
18	The next generation of PDE4 inhibitors 2001 ·Current Opinion in Chemical Biology ·Zheng Huang,Yves Ducharme,Dwight Macdonald,Annette Robichaud	100
19	Integrated Application of Capillary HPLC/Continuous-Flow Liquid Secondary Ion Mass Spectrometry to Discovery Stage Metabolism Studies 1995 ·Analytical Chemistry ·Li Chun,Nathalie Chauret,Yves Ducharme,Laird A. Trimble,Deborah A. Nicoll‐Griffith,James A. Yergey	9
20	Naphthalenic Lignan Lactones as Selective, Nonredox 5-Lipoxygenase Inhibitors. Synthesis and Biological Activity of (Methoxyalkyl)thiazole and Methoxytetrahydropyran Hybrids 1994 ·Journal of Medicinal Chemistry ·Yves Ducharme,Christine Brideau,Daniel Dubé,Chi Chung Chan,Jean‐Pierre Falgueyret,John W. Gillard,Jocelyne Guay,John H. Hutchinson,C. S. McFarlane	31

About Yves Ducharme

Yves Ducharme is a scholar working on Pharmacology, Organic Chemistry and Biochemistry, having authored 33 papers that have together received 1.2k indexed citations. Recurring topics across this work include Inflammatory mediators and NSAID effects (7 papers), Phosphodiesterase function and regulation (7 papers) and Cholinesterase and Neurodegenerative Diseases (6 papers). The work is most often cited by research in Pharmacology (445 citations), Organic Chemistry (541 citations) and Virology (79 citations). Yves Ducharme has collaborated with scholars based in Canada and United States. Frequent co-authors include James D. Wuest, Richard W. Friesen, Christine Brideau, Zheng Huang, Bernard Côté, Dwight Macdonald, Denis Riendeau, Annette Robichaud, Daigen Xu and Joseph A. Mancini. Their work appears in journals such as Journal of the American Chemical Society, Analytical Chemistry and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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