Vito Nacci

2.3k citations

48 papers · 1.6k indexed · h-index 27

Impact in

Virology top 5%
- HIV Research and Treatment
Organic Chemistry top 2%
- Synthesis and Biological Evaluation
- Synthesis and biological activity
- Synthesis and pharmacology of benzodiazepine derivatives

Papers in ⓘ

Virology 5
- HIV Research and Treatment 5
Organic Chemistry 29
- Synthesis and pharmacology of benzodiazepine derivatives 17
- Synthesis and Reactivity of Heterocycles 6

Co-authors: Giuseppe Campiani (47 shared papers)Ettore Novellino (21 shared papers)Caterina Fattorusso (17 shared papers)Isabella Fiorini (21 shared papers)Anna Ramunno (12 shared papers)Stefania Butini (15 shared papers)Daniela M. Zisterer (11 shared papers)Bruno Catalanotti (11 shared papers)
Journals: Journal of Medicinal Chemistry (24 papers)Tetrahedron (5 papers)Journal of Pharmacology and Experimental Therapeutics (2 papers)Journal of Biological Chemistry (2 papers)Current Pharmaceutical Design (2 papers)
Partner nations: Italy Ireland United States

In The Last Decade

Vito Nacci

47 papers receiving 1.6k citations

Peers

Countries citing papers authored by Vito Nacci

Since Specialization

Citations

This map shows the geographic impact of Vito Nacci's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Vito Nacci with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Vito Nacci more than expected).

Fields of papers citing papers by Vito Nacci

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Vito Nacci. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Vito Nacci. The network helps show where Vito Nacci may publish in the future.

Co-authors

The 25 scholars most cited alongside Vito Nacci, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Vito Nacci Line = papers co-authored together Vito Nacci links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 48 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Non-Nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors: Past, Present, and Future Perspectives Current Pharmaceutical Design ·Giuseppe Campiani, Anna Ramunno, Giovanni Maga, Vito Nacci, Caterina Fattorusso, Bruno Catalanotti, Elena Morelli, Ettore Novellino	2002	101
2	Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT₃ Receptor Agonists: Synthesis, Further Structure−Activity Relationships, and Biological Studies Journal of Medicinal Chemistry ·Giuseppe Campiani, Elena Morelli, Sandra Gemma, Vito Nacci, Stefania Butini, M. Hamon, Ettore Novellino, Giovanni Greco, Alfredo Cagnotto, Mara Goegan, Luigi Cervo, Fabio Dalla Valle, Claudia Fracasso, Silvio Caccia, Tiziana Mennini	1999	96
3	Caspase‐3 is not essential for DNA fragmentation in MCF‐7 cells during apoptosis induced by the pyrrolo‐1,5‐benzoxazepine, PBOX‐6 FEBS Letters ·Margaret M. Mc Gee, Edel M. Hyland, Giuseppe Campiani, Anna Ramunno, Vito Nacci, Daniela M. Zisterer	2002	95
4	Synthesis and Pharmacological Evaluation of Potent and Highly Selective D₃ Receptor Ligands: Inhibition of Cocaine-Seeking Behavior and the Role of Dopamine D₃/D₂ Receptors Journal of Medicinal Chemistry ·Giuseppe Campiani, Stefania Butini, Francesco Trotta, Caterina Fattorusso, Bruno Catalanotti, Francesca Aiello, Sandra Gemma, Vito Nacci, Ettore Novellino, Jennifer A. Stark, Alfredo Cagnotto, Elena Fumagalli, Francesco Carnovali, Luigi Cervo, Tiziana Mennini	2003	80
5	Synthesis, Biological Activity, and SARs of Pyrrolobenzoxazepine Derivatives, a New Class of Specific “Peripheral-Type” Benzodiazepine Receptor Ligands Journal of Medicinal Chemistry ·Giuseppe Campiani, Vito Nacci, Isabella Fiorini, Maria P. De Filippis, Antonio Garofalo, Silvia M. Ciani, Giovanni Greco, Ettore Novellino, D. Clive Williams, Daniela M. Zisterer, Margaret J. Woods, Camelia Mihai, Cristina Manzoni, Tiziana Mennini	1996	77
6	Thiazolothiazepine Inhibitors of HIV-1 Integrase Journal of Medicinal Chemistry ·Nouri Neamati, Jim A. Turpin, Heather E. Winslow, John L. Christensen, Karen Williamson, Ann Orr, William G. Rice, Yves Pommier, Antonio Garofalo, Antonella Brizzi, Giuseppe Campiani, Isabella Fiorini, Vito Nacci	1999	77
7	Design, Synthesis, and Structure–Activity Relationship Studies of 4-Quinolinyl- and 9-Acrydinylhydrazones as Potent Antimalarial Agents Journal of Medicinal Chemistry ·Caterina Fattorusso, Giuseppe Campiani, Gagan Kukreja, Marco Persico, Stefania Butini, Maria Pia Romano, Maria Altarelli, Sindu Ros, Margherita Brindisi, Luisa Savini, Ettore Novellino, Vito Nacci, Ernesto Fattorusso, Silvia Parapini, Nicoletta Basilico, Donatella Taramelli, Vanessa Yardley, Simon L. Croft, Marianna Borriello, Sandra Gemma	2008	67
8	Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663 Biochemistry ·Giovanni Maga, Sandra Gemma, Caterina Fattorusso, Giada A. Locatelli, Stefania Butini, Marco Persico, Gagan Kukreja, Maria Pia Romano, Luisa Chiasserini, Luisa Savini, Ettore Novellino, Vito Nacci, Silvio Spadari, Giuseppe Campiani	2005	67
9	Novel and Highly Potent 5-HT₃ Receptor Agonists Based on a Pyrroloquinoxaline Structure Journal of Medicinal Chemistry ·Giuseppe Campiani, Andrea Cappelli, Vito Nacci, Maurizio Anzini, Salvatore Vomero, M. Hamon, Alfredo Cagnotto, Claudia Fracasso, Maria Chiara Uboldi, Silvio Caccia, S. Consolo, Tiziana Mennini	1997	63
10	Development of Molecular Probes for the Identification of Extra Interaction Sites in the Mid-Gorge and Peripheral Sites of Butyrylcholinesterase (BuChE). Rational Design of Novel, Selective, and Highly Potent BuChE Inhibitors Journal of Medicinal Chemistry ·Giuseppe Campiani, Caterina Fattorusso, Stefania Butini, Alessandra Gaeta, Marianna Agnusdei, Sandra Gemma, Marco Persico, Bruno Catalanotti, Luisa Savini, Vito Nacci, Ettore Novellino, Harold W. Holloway, Nigel H. Greig, Tatyana Belinskaya, James M. Fedorko, Ashima Saxena	2004	58
11	Exploiting Protein Fluctuations at the Active-Site Gorge of Human Cholinesterases: Further Optimization of the Design Strategy to Develop Extremely Potent Inhibitors Journal of Medicinal Chemistry ·Stefania Butini, Giuseppe Campiani, Marianna Borriello, Sandra Gemma, Alessandro Panico, Marco Persico, Bruno Catalanotti, Sindu Ros, Margherita Brindisi, Marianna Agnusdei, Isabella Fiorini, Vito Nacci, Ettore Novellino, Tatyana Belinskaya, Ashima Saxena, Caterina Fattorusso	2008	50
12	A Rational Approach to the Design of Selective Substrates and Potent Nontransportable Inhibitors of the Excitatory Amino Acid Transporter EAAC1 (EAAT3). New Glutamate and Aspartate Analogues as Potential Neuroprotective Agents Journal of Medicinal Chemistry ·Giuseppe Campiani, Meri De Angelis, Silvia Armaroli, Caterina Fattorusso, Bruno Catalanotti, Anna Ramunno, Vito Nacci, Ettore Novellino, Christof Grewer, Diana Beşliu-Ionescu, Thomas Rauen, Roger Griffiths, Colin Sinclair, Elena Fumagalli, Tiziana Mennini	2001	48
13	Pyrrolo[1,5]benzoxa(thia)zepines as a New Class of Potent Apoptotic Agents. Biological Studies and Identification of an Intracellular Location of Their Drug Target Journal of Medicinal Chemistry ·Margaret M. Mc Gee, Sandra Gemma, Stefania Butini, Anna Ramunno, Daniela M. Zisterer, Caterina Fattorusso, Bruno Catalanotti, Gagan Kukreja, Isabella Fiorini, Claudio Pisano, C Cucco, Ettore Novellino, Vito Nacci, D. Clive Williams, Giuseppe Campiani	2005	48
14	Discovery of Huperzine A−Tacrine Hybrids as Potent Inhibitors of Human Cholinesterases Targeting Their Midgorge Recognition Sites Journal of Medicinal Chemistry ·Sandra Gemma, Emanuele Gabellieri, Paul B. Huleatt, Caterina Fattorusso, Marianna Borriello, Bruno Catalanotti, Stefania Butini, Meri De Angelis, Ettore Novellino, Vito Nacci, Tatyana Belinskaya, Ashima Saxena, Giuseppe Campiani	2006	42
15	New Antipsychotic Agents with Serotonin and Dopamine Antagonist Properties Based on a Pyrrolo[2,1-b][1,3]benzothiazepine Structure Journal of Medicinal Chemistry ·Giuseppe Campiani, Vito Nacci, Susanna Bechelli, Silvia M. Ciani, Antonio Garofalo, Isabella Fiorini, Håkan Wikström, Peter de Boer, Yi Liao, Pieter G. Tepper, Alfredo Cagnotto, Tiziana Mennini	1998	41
16	Pyrrolobenzothiazepinones and Pyrrolobenzoxazepinones: Novel and Specific Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors with Antiviral Activity Journal of Medicinal Chemistry ·Giuseppe Campiani, Vito Nacci, Isabella Fiorini, Maria P. De Filippis, Antonio Garofalo, Giovanni Greco, Ettore Novellino, Sergio Altamura, Laura Di Renzo	1996	39
17	Neuronal High-Affinity Sodium-Dependent Glutamate Transporters (EAATs): Targets for the Development of Novel Therapeutics Against Neurodegenerative Diseases Current Pharmaceutical Design ·Giuseppe Campiani, Caterina Fattorusso, Meri De Angelis, Bruno Catalanotti, Stefania Butini, Roberto Fattorusso, Isabella Fiorini, Vito Nacci, Ettore Novellino	2003	37
18	Activation of the c-Jun N-terminal Kinase (JNK) Signaling Pathway Is Essential during PBOX-6-induced Apoptosis in Chronic Myelogenous Leukemia (CML) Cells Journal of Biological Chemistry ·Margaret M. Mc Gee, Giuseppe Campiani, Anna Ramunno, Vito Nacci, Mark Lawler, D. Clive Williams, Daniela M. Zisterer	2002	37
19	Diltiazem-like Calcium Entry Blockers: A Hypothesis of the Receptor-Binding Site Based on a Comparative Molecular Field Analysis Model Journal of Medicinal Chemistry ·Federico Corelli, Fabrizio Manetti, Andrea Tafi, Giuseppe Campiani, Vito Nacci, Maurizio Botta	1997	35
20	Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore Journal of Medicinal Chemistry ·Sandra Gemma, Giuseppe Campiani, Stefania Butini, Gagan Kukreja, Bhupendra P. Joshi, Marco Persico, Bruno Catalanotti, Ettore Novellino, Ernesto Fattorusso, Vito Nacci, Luisa Savini, Donatella Taramelli, Nicoletta Basilico, Giulia Morace, Vanessa Yardley, Caterina Fattorusso	2007	35

About Vito Nacci

Vito Nacci is a scholar working on Virology, Organic Chemistry, Cellular and Molecular Neuroscience, Infectious Diseases and Pharmacology, having authored 48 papers that have together received 1.6k indexed citations. Recurring topics across this work include Synthesis and pharmacology of benzodiazepine derivatives (17 papers), HIV/AIDS drug development and treatment (8 papers), Neuroscience and Neuropharmacology Research (7 papers), Cancer therapeutics and mechanisms (7 papers), Synthesis and Reactivity of Heterocycles (6 papers), Computational Drug Discovery Methods (6 papers), Cholinesterase and Neurodegenerative Diseases (6 papers) and HIV Research and Treatment (5 papers). The work is most often cited by research in Virology (172 citations), Organic Chemistry (814 citations), Infectious Diseases (249 citations), Cellular and Molecular Neuroscience (238 citations) and Pharmacology (216 citations). Vito Nacci has collaborated with scholars based in Italy, Ireland and United States. Frequent co-authors include Giuseppe Campiani, Ettore Novellino, Caterina Fattorusso, Isabella Fiorini, Anna Ramunno, Stefania Butini, Daniela M. Zisterer, Bruno Catalanotti, Tiziana Mennini and Sandra Gemma. Their work appears in journals such as Journal of Medicinal Chemistry, Tetrahedron, Journal of Pharmacology and Experimental Therapeutics, Journal of Biological Chemistry and Current Pharmaceutical Design.

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