Tohru Funahashi

73.4k total citations · 31 hit papers
337 papers, 55.5k citations indexed

About

Tohru Funahashi is a scholar working on Epidemiology, Physiology and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Tohru Funahashi has authored 337 papers receiving a total of 55.5k indexed citations (citations by other indexed papers that have themselves been cited), including 213 papers in Epidemiology, 128 papers in Physiology and 111 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Tohru Funahashi's work include Adipokines, Inflammation, and Metabolic Diseases (208 papers), Adipose Tissue and Metabolism (102 papers) and Cardiovascular Disease and Adiposity (61 papers). Tohru Funahashi is often cited by papers focused on Adipokines, Inflammation, and Metabolic Diseases (208 papers), Adipose Tissue and Metabolism (102 papers) and Cardiovascular Disease and Adiposity (61 papers). Tohru Funahashi collaborates with scholars based in Japan, United States and Belgium. Tohru Funahashi's co-authors include Yūji Matsuzawa, Shinji Kihara, Iichiro Shimomura, Noriyuki Ouchi, Tadashi Nakamura, Kikuko Hotta, Yukio Arita, Norikazu Maeda, Sachiyo Tanaka and Hiroshi Kuriyama and has published in prestigious journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

Tohru Funahashi

335 papers receiving 53.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity

1999 4.1k citations Shinji Kihara, Noriyuki Ouchi et al. Biochemical and Biophysical Research Communications profile →
Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia

2001 2.9k citations Tohru Funahashi, Sachiyo Tanaka et al. The Journal of Clinical Endocrinology & Metabolism profile →
Novel Modulator for Endothelial Adhesion Molecules

1999 1.8k citations Noriyuki Ouchi, Shinji Kihara et al. profile →
cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 (AdiposeMost Abundant Gene Transcript 1)

1996 1.7k citations Iichiro Shimomura, Tohru Funahashi et al. Biochemical and Biophysical Research Communications profile →
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

2002 1.7k citations Norikazu Maeda, Iichiro Shimomura et al. profile →
Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-κB Signaling Through a cAMP-Dependent Pathway

2000 1.5k citations Noriyuki Ouchi, Shinji Kihara et al. profile →
PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

2001 1.4k citations Norikazu Maeda, Masahiko Takahashi et al. profile →
Association of Hypoadiponectinemia With Coronary Artery Disease in Men

2003 1.2k citations Shinji Kihara, Noriyuki Ouchi et al. profile →
Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

2000 1.1k citations Takafumi Yokota, Kenji Oritani et al. profile →
Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages

2001 1.1k citations Noriyuki Ouchi, Shinji Kihara et al. profile →
Adiponectin and Metabolic Syndrome

2003 975 citations Yūji Matsuzawa, Tohru Funahashi et al. profile →
Weight Reduction Increases Plasma Levels of an Adipose-Derived Anti-Inflammatory Protein, Adiponectin

2001 969 citations Wei‐Shiung Yang, Wen‐Jeng Lee et al. The Journal of Clinical Endocrinology & Metabolism profile →
Adiponectin and development of type 2 diabetes in the Pima Indian population

2002 887 citations Tohru Funahashi, Yūji Matsuzawa et al. profile →
Adiponectin Reduces Atherosclerosis in Apolipoprotein E-Deficient Mice

2002 871 citations Shinji Kihara, Noriyuki Ouchi et al. profile →
Circulating Concentrations of the Adipocyte Protein Adiponectin Are Decreased in Parallel With Reduced Insulin Sensitivity During the Progression to Type 2 Diabetes in Rhesus Monkeys

2001 870 citations Tohru Funahashi, Yūji Matsuzawa et al. profile →
Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms

2005 835 citations Shinji Kihara, Tohru Funahashi et al. profile →
Adiponectin Stimulates Production of Nitric Oxide in Vascular Endothelial Cells

2003 825 citations Tohru Funahashi, Iichiro Shimomura et al. profile →
Androgens Decrease Plasma Adiponectin, an Insulin-Sensitizing Adipocyte-Derived Protein

2002 689 citations Hitoshi Nishizawa, Iichiro Shimomura et al. profile →
Abdominal Fat: Standardized Technique for Measurement at CT

1999 685 citations Tadashi Nakamura, Tohru Funahashi et al. profile →
Reciprocal Association of C-Reactive Protein With Adiponectin in Blood Stream and Adipose Tissue

2003 679 citations Noriyuki Ouchi, Shinji Kihara et al. profile →
Role of Adiponectin in Preventing Vascular Stenosis

2002 677 citations Iichiro Shimomura, Makoto Nishida et al. profile →
Adiponectin, Metabolic Risk Factors, and Cardiovascular Events among Patients with End-Stage Renal Disease

2002 672 citations Sachiyo Tanaka, Noriyuki Ouchi et al. profile →
Adiponectin Stimulates Angiogenesis by Promoting Cross-talk between AMP-activated Protein Kinase and Akt Signaling in Endothelial Cells

2004 660 citations Noriyuki Ouchi, Shinji Kihara et al. profile →
Induction of Adiponectin, a Fat-Derived Antidiabetic and Antiatherogenic Factor, by Nuclear Receptors

2003 641 citations Norikazu Maeda, Tohru Funahashi et al. profile →
Adiponectin as a Biomarker of the Metabolic Syndrome

2004 636 citations Tadashi Nakamura, Shinji Kihara et al. profile →
Obesity, adiponectin and vascular inflammatory disease

2003 600 citations Noriyuki Ouchi, Shinji Kihara et al. Current Opinion in Lipidology profile →
Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis

2004 593 citations Shinji Kihara, Yūji Matsuzawa et al. Proceedings of the National Academy of Sciences profile →
Adiponectin-mediated modulation of hypertrophic signals in the heart

2004 587 citations Noriyuki Ouchi, Shinji Kihara et al. profile →
Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell

2002 564 citations Shinji Kihara, Noriyuki Ouchi et al. profile →
Selective Suppression of Endothelial Cell Apoptosis by the High Molecular Weight Form of Adiponectin

2004 556 citations Hideki Kobayashi, Noriyuki Ouchi et al. profile →
Hypoadiponectinemia Is an Independent Risk Factor for Hypertension

2004 514 citations Noriyuki Ouchi, Shinji Kihara et al. profile →

Peers

Countries citing papers authored by Tohru Funahashi

Since Specialization

Citations

This map shows the geographic impact of Tohru Funahashi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tohru Funahashi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tohru Funahashi more than expected).

Fields of papers citing papers by Tohru Funahashi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tohru Funahashi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tohru Funahashi. The network helps show where Tohru Funahashi may publish in the future.

Co-authorship network of co-authors of Tohru Funahashi

This figure shows the co-authorship network connecting the top 25 collaborators of Tohru Funahashi. A scholar is included among the top collaborators of Tohru Funahashi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tohru Funahashi. Tohru Funahashi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Autoimmune Severe Hypertriglyceridemia Induced by Anti-Apolipoprotein C-II Antibody 2014 ·The Journal of Clinical Endocrinology & Metabolism ·Hiroyasu Yamamoto, Minoru Tanaka, (unknown), Tohru Funahashi, Iichiro Shimomura, Shinji Kihara	16
2	Gene expression levels of S100 protein family in blood cells are associated with insulin resistance and inflammation (Peripheral blood S100 mRNAs and metabolic syndrome) 2013 ·Biochemical and Biophysical Research Communications ·Masaya Yamaoka, Norikazu Maeda, Seiji Nakamura, Takuya Mori, Kana Inoue, Keisuke Matsuda, Ryohei Sekimoto, Susumu Kashine, Yasuhiko Nakagawa, Yu Tsushima, Yuya Fujishima, Noriyuki Komura, Ayumu Hirata, Hitoshi Nishizawa, Yūji Matsuzawa, Kenichi Matsubara, Tohru Funahashi, Iichiro Shimomura	37
3	Weight reduction is associated with improvement of glycemic control in Japanese men, whose hemoglobin A1C is 5.6–6.4%, with visceral fat accumulation, but not without visceral fat accumulation 2013 ·Journal of Diabetes Investigation ·Yukiyoshi Okauchi, Hiromi Iwahashi, Kohei Okita, Tohru Funahashi, Ken Kishida, Midori Noguchi, Tetsuya Ohira, Tadashi Nakamura, Akihisa Imagawa, Iichiro Shimomura	6
4	Involvement of Endothelial Apoptosis Underlying Chronic Obstructive Pulmonary Disease–like Phenotype in Adiponectin-null Mice: Implications for Therapy 2011 ·American Journal of Respiratory and Critical Care Medicine ·Kaori Nakanishi, Yoshito Takeda, Satoshi Tetsumoto, Takeo Iwasaki, Kazuyuki Tsujino, Hanako Kuhara, Yingji Jin, Izumi Nagatomo, Hiroshi Kida, (unknown), Takashi Kijima, Norikazu Maeda, Tohru Funahashi, Iichiro Shimomura, Isao Tachibana, Ichiro Kawase	57
5	Liraglutide is effective in type 2 diabetic patients with sustained endogenous insulin‐secreting capacity 2011 ·Journal of Diabetes Investigation ·Junji Kozawa, Kana Inoue, (unknown), (unknown), Yukiyoshi Okauchi, Susumu Kashine, Tetsuhiro Kitamura, Norikazu Maeda, Kohei Okita, Hiromi Iwahashi, Tohru Funahashi, Akihisa Imagawa, Iichiro Shimomura	39
6	Adiponectin deficiency enhanced the severity of cerulein-induced chronic pancreatitis in mice 2010 ·Journal of Gastroenterology ·Takuya Yamada, (unknown), Kenji Watabe, Yoshihiro Kamada, Shinichi Kiso, Hideharu Ogiyama, (unknown), Shinji Kihara, Tohru Funahashi, Iichiro Shimomura, Shusaku Tsutsui, Norio Hayashi	24
7	Natriuretic Peptides Enhance the Production of Adiponectin in Human Adipocytes and in Patients With Chronic Heart Failure 2009 ·Journal of the American College of Cardiology ·Osamu Tsukamoto, Masashi Fujita, Mahoto Kato, Satoru Yamazaki, Yoshihiro Asano, Akiko Ogai, Hidetoshi Okazaki, Mitsutoshi Asai, Y. Nagamachi, Norikazu Maeda, Yasunori Shintani, Tetsuo Minamino, Masanori Asakura, Ichiro Kishimoto, Tohru Funahashi, Hitonobu Tomoike, Masafumi Kitakaze	218
8	Nocturnal reduction in circulating adiponectin concentrations related to hypoxic stress in severe obstructive sleep apnea-hypopnea syndrome 2008 ·American Journal of Physiology-Endocrinology and Metabolism ·Yasuhiko Nakagawa, Ken Kishida, Shinji Kihara, Mina Sonoda, Ayumu Hirata, Atsutaka Yasui, Hitoshi Nishizawa, Tadashi Nakamura, Ryoko Yoshida, Iichiro Shimomura, Tohru Funahashi	55
9	Risk Factors of Atherosclerotic Diseases - Executive Summary of Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases for Japanese 2007 ·Journal of Atherosclerosis and Thrombosis ·Tamio Teramoto, Junichi Sasaki, Hirotsugu Ueshima, Genshi Egusa, Makoto Kinoshita, Kazuaki Shimamoto, Hiroyuki Daida, Sadatoshi Biro, Kazuhiko Hirobe, Tohru Funahashi, Koutaro Yokote, Masayuki Yokode	46
10	Pravastatin improved glucose metabolism associated with increasing plasma adiponectin in patients with impaired glucose tolerance and coronary artery disease 2006 ·Atherosclerosis ·Seigo Sugiyama, Hironobu Fukushima, Kiyotaka Kugiyama, Hidetomo Maruyoshi, Sunao Kojima, Tohru Funahashi, Tomohiro Sakamoto, Yoko Horibata, Keisuke Watanabe, Hidenobu Koga, Koichi Sugamura, Fumiyuki Otsuka, (unknown), Hisao Ogawa	72
11	Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase 2005 ·Proceedings of the National Academy of Sciences ·Toshiyuki Hibuse, Norikazu Maeda, Tohru Funahashi, Kaori Yamamoto, Azumi Nagasawa, Wataru Mizunoya, Ken Kishida, Kazuo Inoue, Hiroshi Kuriyama, Tadashi Nakamura, Tohru Fushiki, Shinji Kihara, Iichiro Shimomura	244
12	Adiponectin Stimulates Angiogenesis in Developing Murine Retina 2005 ·Investigative Ophthalmology & Visual Science ·Takeshi Kimura, Hitoshi Takagi, Kiyoshi Suzuma, Daisuke Watanabe, Shinji Kihara, Tohru Funahashi, Hideto Katsuta, Noriko Yoshimura	1
13	Adiponectin and inflammatory markers in peripheral arterial occlusive disease 2005 ·Atherosclerosis ·Yoshio Iwashima, Takeshi Horio, Yoshihiko Suzuki, Shinji Kihara, Hiromi Rakugi, Kenji Kangawa, Tohru Funahashi, Toshio Ogihara, Yuhei Kawano	63
14	Obesity, adiponectin and vascular inflammatory disease breakdown → 2003 ·Current Opinion in Lipidology ·Noriyuki Ouchi, Shinji Kihara, Tohru Funahashi, Yūji Matsuzawa, Kenneth Walsh	600
15	Adiponectin, a Fat Cell Product, Influences the Earliest Lymphocyte Precursors in Bone Marrow Cultures by Activation of the Cyclooxygenase-Prostaglandin Pathway in Stromal Cells 2003 ·The Journal of Immunology ·Takafumi Yokota, C.S. Reddy Meka, Taku Kouro, Kay L. Medina, Hideya Igarashi, Masahiko Takahashi, Kenji Oritani, Tohru Funahashi, Yoshiaki Tomiyama, Yūji Matsuzawa, Paul W. Kincade	111
16	Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins 2002 ·Journal of Clinical Investigation ·Takafumi Yokota, C.S. Reddy Meka, Kay L. Medina, Hideya Igarashi, P C Comp, Masahiko Takahashi, Makoto Nishida, Kenji Oritani, Jun-ichiro Miyagawa, Tohru Funahashi, Yoshiaki Tomiyama, Yūji Matsuzawa, Paul W. Kincade	123
17	Weight Reduction Increases Plasma Levels of an Adipose-Derived Anti-Inflammatory Protein, Adiponectin breakdown → 2001 ·The Journal of Clinical Endocrinology & Metabolism ·Wei‐Shiung Yang, Wen‐Jeng Lee, Tohru Funahashi, Sachiyo Tanaka, Yūji Matsuzawa, (unknown), Chi‐Ling Chen, Tong‐Yuan Tai, Lee‐Ming Chuang	969
18	Importance of intra-abdominal visceral fat accumulation to coronary atherosclerosis in heterozygous familial hypercholesterolaemia 1997 ·International Journal of Obesity ·Tadashi Nakamura, Hideki Kobayashi, (unknown), Tsutomu Nakagawa, M. Nishida, Shinji Kihara, (unknown), Satoshi Nozaki, Tohru Funahashi, Shizuya Yamashita, Kaoru Kameda-Takemura, Yūji Matsuzawa	30
19	Selective removal of anti-double-stranded DNA antibodies by immunoadsorption with dextran sulphate in a patient with systemic lupus erythematosus. 1989 ·Annals of the Rheumatic Diseases ·Makiko Kinoshita, S Aotsuka, Tohru Funahashi, Nobutaka Tani, R Yokohari	21
20	Cells of an Internalization-Defective Familial Hypercholesterolemia Mutant Secrete Low Density Lipoprotein Receptors1 1987 ·The Journal of Biochemistry ·Yasuko Miyake, Tohru Funahashi, Akira Yamamoto	3

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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