Xiaohua Shen

12.5k total citations · 8 hit papers
54 papers, 8.6k citations indexed

About

Xiaohua Shen is a scholar working on Molecular Biology, Cancer Research and Cell Biology. According to data from OpenAlex, Xiaohua Shen has authored 54 papers receiving a total of 8.6k indexed citations (citations by other indexed papers that have themselves been cited), including 38 papers in Molecular Biology, 10 papers in Cancer Research and 7 papers in Cell Biology. Recurrent topics in Xiaohua Shen's work include RNA Research and Splicing (17 papers), RNA modifications and cancer (15 papers) and Cancer-related molecular mechanisms research (9 papers). Xiaohua Shen is often cited by papers focused on RNA Research and Splicing (17 papers), RNA modifications and cancer (15 papers) and Cancer-related molecular mechanisms research (9 papers). Xiaohua Shen collaborates with scholars based in China, United States and Japan. Xiaohua Shen's co-authors include Stuart H. Orkin, Randal J. Kaufman, Jianlong Wang, Jianlin Chu, Jonghwan Kim, Kyung‐Ho Lee, Kezhong Zhang, Hiderou Yoshida, Kazutoshi Mori and Kenjiro Sakaki and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Xiaohua Shen

49 papers receiving 8.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

2008 1.1k citations Jonghwan Kim, Jianlin Chu et al. Cell profile →
A protein interaction network for pluripotency of embryonic stem cells

2006 881 citations Jianlong Wang, Jianlin Chu et al. Nature profile →
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

2002 852 citations Kyung‐Ho Lee, Xiaohua Shen et al. profile →
EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency

2008 781 citations Xiaohua Shen, Yuko Fujiwara et al. Molecular Cell profile →
Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response

2006 672 citations Kezhong Zhang, Xiaohua Shen et al. Cell profile →
Complementary Signaling Pathways Regulate the Unfolded Protein Response and Are Required for C. elegans Development

2001 590 citations Xiaohua Shen, Ronald Ellis et al. Cell profile →
The unfolded protein response in nutrient sensing and differentiation

2002 502 citations Randal J. Kaufman, Donalyn Scheuner et al. Nature Reviews Molecular Cell Biology profile →
A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity

2018 352 citations Michelle Percharde, Chih-Jen Lin et al. Cell profile →

Peers

Countries citing papers authored by Xiaohua Shen

Since Specialization

Citations

This map shows the geographic impact of Xiaohua Shen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xiaohua Shen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xiaohua Shen more than expected).

Fields of papers citing papers by Xiaohua Shen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xiaohua Shen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xiaohua Shen. The network helps show where Xiaohua Shen may publish in the future.

Co-authorship network of co-authors of Xiaohua Shen

This figure shows the co-authorship network connecting the top 25 collaborators of Xiaohua Shen. A scholar is included among the top collaborators of Xiaohua Shen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xiaohua Shen. Xiaohua Shen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Condensation of ZFP207 and U1 snRNP promotes spliceosome assembly 2025 ·Nature Structural & Molecular Biology ·Yuenan Zhou, (unknown), Zuokun Shi, (unknown), Xushen Xiong, Xiaohua Shen, Xiaoyu Li, Yafei Yin	2
2	Mitochondrial homeostasis restoring peptide-drug conjugates with ROS-responsive NO releasing ability for targeted therapy of myocardial infarction 2025 ·Journal of Nanobiotechnology ·Zhao‐Yang Lu, Qing Chai, Wenbin Dai, Bo Yu, Qingbo Lv, Fuyu Qiu, Jing Gao, Juhong Zhang, Xiaohua Shen, Shengyu Chen, Zhida Shen, Min Shang, (unknown), Guosheng Fu, (unknown), (unknown), Fan Jia	3
3	What tool or method do you wish existed? 2024 ·Cell ·Yvonne Y. Chen, Charles L. Evavold, Matthias Mann, Emily Davenport, Margaret McFall‐Ngai, Magda Bienko, Hiroki R. Ueda, Lin Tian, (unknown), (unknown), Junjie Liu, Tara L. Deans, Xiaohua Shen	2
4	Noncoding RNA-chromatin association: Functions and mechanisms 2023 ·Fundamental Research ·Yafei Yin, Xiaohua Shen	9
5	RYBP/YAF2-PRC1 complexes and histone H1-dependent chromatin compaction mediate propagation of H2AK119ub1 during cell division 2020 ·Nature Cell Biology ·Jicheng Zhao, Min Wang, Luyuan Chang, Juan Yu, (unknown), Cuifang Liu, Wenjun Huang, Tiantian Zhang, Xudong Wu, Xiaohua Shen, Bing Zhu, Guohong Li	84
6	U1 snRNP regulates chromatin retention of noncoding RNAs 2020 ·Nature ·Yafei Yin, Jiayun Lu, Xuechun Zhang, Wen Shao, Yanhui Xu, Pan Li, Yantao Hong, Li Cui, Ge Shan, Bin Tian, Qiangfeng Cliff Zhang, Xiaohua Shen	142
7	RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control 2019 ·Molecular Cell ·Xianju Bi, Yanhui Xu, Tong Li, Xinmin Li, Wenzhi Li, Wen Shao, Kaili Wang, Ge Zhan, (unknown), Wei Liu, Jiangbo Lu, Liang Wang, Jicheng Zhao, Jiawei Wu, Jie Na, Guohong Li, Pilong Li, Xiaohua Shen	50
8	A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity breakdown → 2018 ·Cell ·Michelle Percharde, Chih-Jen Lin, Yafei Yin, Juan Guan, (unknown), Aydan Bulut-Karslıoğlu, Steffen Biechele, Bo Huang, Xiaohua Shen, Miguel Ramalho‐Santos	352
9	Histone H2A Ubiquitination Inhibits the Enzymatic Activity of H3 Lysine 36 Methyltransferases 2013 ·Journal of Biological Chemistry ·(unknown), Ben Ma, Yuan Wen, Zhuqiang Zhang, Ping Chen, Xiaojun Ding, Feng Li, Xiaohua Shen, She Chen, Guohong Li, Bing Zhu	56
10	RNA surveillance is required for endoplasmic reticulum homeostasis 2012 ·Proceedings of the National Academy of Sciences ·Kenjiro Sakaki, Sawako Yoshina, Xiaohua Shen, Jaeseok Han, (unknown), (unknown), Shohei Mitani, Randal J. Kaufman	67
11	ロシグリタゾンはERK/MAPK及びNF-κBシグナル経路を経てTNF-αにより誘発された内皮前駆細胞アポトーシスを減弱する 2011 ·Journal of Pharmacological Sciences ·(unknown), Yanbo Zhao, (unknown), Xiaohua Shen, Ding Zhi Fang, (unknown)	1
12	Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncogenic Transformation 2011 ·Cancer Cell ·Boris G. Wilson, Xi Wang, Xiaohua Shen, Elizabeth S. McKenna, Madeleine E. Lemieux, Yoon‐Jae Cho, Edward C. Koellhoffer, Scott L. Pomeroy, Stuart H. Orkin, Charles W.M. Roberts	10
13	Jumonji Modulates Polycomb Activity and Self-Renewal versus Differentiation of Stem Cells 2009 ·Cell ·Xiaohua Shen, Woojin Kim, Yuko Fujiwara, Matthew D. Simon, Yingchun Liu, Matthew R. Mysliwiec, Guo‐Cheng Yuan, Youngsook Lee, Stuart H. Orkin	338
14	An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells breakdown → 2008 ·Cell ·Jonghwan Kim, Jianlin Chu, Xiaohua Shen, Jianlong Wang, Stuart H. Orkin	1053
15	An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells 2008 ·Cell ·Jonghwan Kim, Jianlin Chu, Xiaohua Shen, Jianlong Wang, Stuart H. Orkin	56
16	Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response breakdown → 2006 ·Cell ·Kezhong Zhang, Xiaohua Shen, Jun Wu, Kenjiro Sakaki, Thomas L. Saunders, D. Thomas Rutkowski, Sung Hoon Back, Randal J. Kaufman	672
17	Genetic Interactions Due to Constitutive and Inducible Gene Regulation Mediated by the Unfolded Protein Response in C. elegans 2005 ·PLoS Genetics ·Xiaohua Shen, Ronald Ellis, Kenjiro Sakaki, Randal J. Kaufman	197
18	Influences of the Current Breaking of the Yellow River on the Anomalous Vertical Development and Evolution of the River Course 2003 ·Dizhi lunping ·Xiaohua Shen	3
19	The unfolded protein response in nutrient sensing and differentiation breakdown → 2002 ·Nature Reviews Molecular Cell Biology ·Randal J. Kaufman, Donalyn Scheuner, Martin Schröder, Xiaohua Shen, Kyung‐Ho Lee, Chuan Yin Liu, Stacey Arnold	502
20	Comparative analysis of early and mid-stage nerve decompression and nerve anastomosis for traumatic recurrent laryngeal nerve injuries 1990 ·Zhonghua chuangshang zazhi ·Shicai Chen, (unknown), (unknown), Zhaoji Li, Suqin Zhang, (unknown), Gang Chen, Xiaohua Shen, (unknown), (unknown), (unknown)	0

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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