Jaeseok Han

5.6k citations

57 papers · 4.4k indexed · 3 hit papers · h-index 28

Impact in

Cell Biology top 0.2%
- Endoplasmic Reticulum Stress and Disease
Aging top 5%

Papers in

Aging 4
- Genetics, Aging, and Longevity in Model Organisms 4
Cell Biology 37
- Endoplasmic Reticulum Stress and Disease 36

Co-authors: Randal J. Kaufman Sung Hoon Back Robert Gildersleeve Shiyu Wang Maureen A. Sartor Maria Hatzoglou Celvie L. Yuan Dawid Krokowski
Journals: International Journal of Molecular Sciences (5 papers)Journal of Biological Chemistry (4 papers)Diabetes (3 papers)Cell Metabolism (2 papers)Cells (2 papers)
Partner nations: South Korea United States Canada

In The Last Decade

Jaeseok Han

56 papers receiving 4.3k citations

Hit Papers

align trajectories log scale

Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus 2021 · 155 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Nature Reviews Endocrinology
2016 Journal of Lipid Research
2013 Nature Cell Biology

Peers

Countries citing papers authored by Jaeseok Han

Since Specialization

Citations

This map shows the geographic impact of Jaeseok Han's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jaeseok Han with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jaeseok Han more than expected).

Fields of papers citing papers by Jaeseok Han

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jaeseok Han. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jaeseok Han. The network helps show where Jaeseok Han may publish in the future.

Co-authors

The 25 scholars most cited alongside Jaeseok Han, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jaeseok Han Line = papers co-authored together Jaeseok Han links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	GDF15 regulates development and growth of sympathetic neurons to enhance energy expenditure and thermogenesis Experimental & Molecular Medicine ·Jinyoung Kim, Aiping Zhao, S.H. Park, Jaeseok Han, Deok-Hyeon Cheon, Sang Hyeon Ju, Yongwoo Jang, Kon Chu, Hyung Jin Choi, Jiyoon Kim, Myung‐Shik Lee	2025	0
2	The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1) Journal of Biological Chemistry ·Zeenat Farooq, Fedho Kusuma, Phillip C. Burke, Catherine R. Dufour, Duckgue Lee, Negar Tabatabaei, Phoenix Toboz, Ernest Radovani, Jack Greenblatt, Jalees Rehman, Jacob Class, Arkady Khoutorsky, Bruno D. Fonseca, Justin M. Richner, Eloi Mercier, Guillaume Bourque, Vincent Giguère, Arvind R. Subramaniam, Jaeseok Han, Soroush Tahmasebi	2022	9
3	Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus Nature Reviews Endocrinology ·Jing Yong, James D. Johnson, Peter Arvan, Jaeseok Han, Randal J. Kaufman Hit paper breakdown →	2021	155
4	Characterization of Endoplasmic Reticulum (ER) in Human Pluripotent Stem Cells Revealed Increased Susceptibility to Cell Death upon ER Stress Cells ·Tae Won Ha, Ji Hun Jeong, HyeonSeok Shin, Kyu‐hyun Kim, Jeong Suk Im, Byung Hoo Song, Jacob H. Hanna, Jae Sang Oh, Dong‐Hun Woo, Jaeseok Han, Man Ryul Lee	2020	12
5	TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation Nature Communications ·Hyun‐Kyoung Kim, Kashi Raj Bhattarai, Raghu Patil Junjappa, Jin Hee Ahn, Suvarna H. Pagire, Hyun Ju Yoo, Jaeseok Han, Duckgue Lee, Kyung‐Woon Kim, Hyung‐Ryong Kim, Han–Jung Chae	2020	43
6	PERK-mediated induction of microRNA-483 disrupts cellular ATP homeostasis during the unfolded protein response Journal of Biological Chemistry ·Nobuhiko Hiramatsu, Karen Chiang, Cathrine Aivati, Jeffrey J. Rodvold, Ji-Min Lee, Jaeseok Han, Leon Chea, Maurizio Zanetti, Edward H. Koo, Jonathan H. Lin	2019	22
7	Physiological/pathological ramifications of transcription factors in the unfolded protein response Genes & Development ·Jaeseok Han, Randal J. Kaufman	2017	95
8	Coordinating Organismal Metabolism During Protein Misfolding in the ER Through the Unfolded Protein Response Current topics in microbiology and immunology ·Vishwanatha K. Chandrahas, Jaeseok Han, Randal J. Kaufman	2017	8
9	The role of ER stress in lipid metabolism and lipotoxicity Journal of Lipid Research ·Jaeseok Han, Randal J. Kaufman Hit paper breakdown →	2016	486
10	Identification of protein disulfide isomerase 1 as a key isomerase for disulfide bond formation in apolipoprotein B100 Molecular Biology of the Cell ·Shiyu Wang, Shuin Park, Vamsi K. Kodali, Jaeseok Han, Theresa Yip, Zhouji Chen, Nicholas O. Davidson, Randal J. Kaufman	2014	21
11	Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2 PLoS Genetics ·Marzia Scortegagna, Hyungsoo Kim, Jian‐Liang Li, Hang Yao, Laurence M. Brill, Jaeseok Han, Eric Lau, David D.L. Bowtell, Gabriel Haddad, Randal J. Kaufman, Ze’ev A. Ronai	2014	29
12	Measurement of the Unfolded Protein Response to Investigate Its Role in Adipogenesis and Obesity Methods in enzymology on CD-ROM/Methods in enzymology ·Jaeseok Han, Randal J. Kaufman	2014	16
13	ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death Nature Cell Biology ·Jaeseok Han, Sung Hoon Back, Junguk Hur, Yu-Hsuan Lin, Robert Gildersleeve, Jixiu Shan, Celvie L. Yuan, Dawid Krokowski, Shiyu Wang, Maria Hatzoglou, Michael S. Kilberg, Maureen A. Sartor, Randal J. Kaufman Hit paper breakdown →	2013	1315
14	ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice Diabetologia ·Jaeseok Han, Rachana Murthy, Brent M. Wood, Benbo Song, S. Wang, Bingbing Sun, Harmeet Malhi, Randal J. Kaufman	2013	99
15	RNA surveillance is required for endoplasmic reticulum homeostasis Proceedings of the National Academy of Sciences ·Kenjiro Sakaki, Sawako Yoshina, Xiaohua Shen, Jaeseok Han, Melinda R. DeSantis, Mon Xiong, Shohei Mitani, Randal J. Kaufman	2012	67
16	The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β ‐cells Diabetes Obesity and Metabolism ·Randal J. Kaufman, Sung Hoon Back, Benbo Song, Jaeseok Han, Justin Hassler	2010	102
17	Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells Cell Metabolism ·Sung Hoon Back, Donalyn Scheuner, Jaeseok Han, Benbo Song, Mark Ribick, Junying Wang, Robert Gildersleeve, Subramaniam Pennathur, Randal J. Kaufman	2009	292
18	Engineered Enteroendocrine Cells Secrete Insulin in Response to Glucose and Reverse Hyperglycemia in Diabetic Mice Molecular Therapy ·Jaeseok Han, Hyune-Hwan Lee, Hyokjoon Kwon, Seungjin Shin, Ji-Won Yoon, Hee‐Sook Jun	2007	23
19	Gamma Interferon Paradoxically Inhibits the Development of Diabetes in the NOD Mouse Journal of Autoimmunity ·Douglas O. Sobel, Jaeseok Han, Joy Williams, Ji‐Won Yoon, Hee‐Sook Jun, Behrouz Ahvazi	2002	39
20	Selective Transcriptional Regulations in the Human Liver Cell by Hepatitis B Viral X Protein Biochemical and Biophysical Research Communications ·Jaeseok Han, Hae Yong Yoo, Byung Hyune Choi, Hyune Mo Rho	2000	53

About Jaeseok Han

Jaeseok Han is a scholar working on Aging, Cell Biology, Epidemiology, Surgery and Endocrinology, Diabetes and Metabolism, having authored 57 papers that have together received 4.4k indexed citations. Recurring topics across this work include Endoplasmic Reticulum Stress and Disease (36 papers), Pancreatic function and diabetes (22 papers), Autophagy in Disease and Therapy (14 papers), Diabetes and associated disorders (9 papers), RNA regulation and disease (7 papers), CRISPR and Genetic Engineering (5 papers), Genetics, Aging, and Longevity in Model Organisms (4 papers) and Adipose Tissue and Metabolism (4 papers). The work is most often cited by research in Cell Biology (2.2k citations), Aging (83 citations), Epidemiology (1.3k citations), Molecular Biology (2.0k citations) and Biochemistry (197 citations). Jaeseok Han has collaborated with scholars based in South Korea, United States and Canada. Frequent co-authors include Randal J. Kaufman, Sung Hoon Back, Robert Gildersleeve, Shiyu Wang, Maureen A. Sartor, Maria Hatzoglou, Celvie L. Yuan, Dawid Krokowski, Jixiu Shan and Michael S. Kilberg. Their work appears in journals such as International Journal of Molecular Sciences, Journal of Biological Chemistry, Diabetes, Cell Metabolism and Cells.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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