Xia Bu

9.7k total citations · 2 hit papers
27 papers, 5.6k citations indexed

About

Xia Bu is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Xia Bu has authored 27 papers receiving a total of 5.6k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Immunology, 11 papers in Oncology and 8 papers in Molecular Biology. Recurrent topics in Xia Bu's work include Cancer Immunotherapy and Biomarkers (9 papers), Immune Cell Function and Interaction (7 papers) and Immunotherapy and Immune Responses (5 papers). Xia Bu is often cited by papers focused on Cancer Immunotherapy and Biomarkers (9 papers), Immune Cell Function and Interaction (7 papers) and Immunotherapy and Immune Responses (5 papers). Xia Bu collaborates with scholars based in United States, China and Japan. Xia Bu's co-authors include Gordon J. Freeman, Shengqing Gu, Ziyi Li, Avinash Sahu, Jun Liu, X. Shirley Liu, Jingxin Fu, Myles Brown, Deng Pan and Nicole Traugh and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nature Medicine.

In The Last Decade

Xia Bu

25 papers receiving 5.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

2018 3.2k citations Peng Jiang, Shengqing Gu et al. Nature Medicine profile →
Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

2017 736 citations Jinfang Zhang, Xia Bu et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Xia Bu United States	17	2.6k	2.3k	2.2k	1.9k	1.4k	27	5.6k
Nikolai N. Khodarev United States	36	2.6k 1.0×	2.0k 0.9×	1.2k 0.5×	1.8k 0.9×	1.1k 0.8×	82	5.3k
Thomas E. Darga United States	25	3.1k 1.2×	1.6k 0.7×	1.2k 0.5×	2.5k 1.3×	746 0.5×	34	5.4k
Sumit K. Subudhi United States	37	4.0k 1.6×	1.5k 0.6×	1.8k 0.8×	3.6k 1.9×	741 0.5×	108	7.3k
Daniela Bruni France	11	2.7k 1.1×	1.2k 0.5×	944 0.4×	2.2k 1.1×	716 0.5×	13	4.4k
Claudia Palena United States	43	3.5k 1.3×	1.9k 0.8×	968 0.4×	3.1k 1.6×	626 0.4×	94	6.0k
Jeremy Stinson United States	18	1.9k 0.7×	3.1k 1.3×	1.4k 0.7×	835 0.4×	750 0.5×	22	5.2k
Ravindra Uppaluri United States	36	3.0k 1.1×	1.5k 0.6×	785 0.4×	2.5k 1.3×	716 0.5×	100	5.2k
Trevor J. Pugh Canada	34	1.4k 0.5×	2.8k 1.2×	700 0.3×	857 0.4×	1.3k 0.9×	149	5.0k
Jianfei Qian United States	37	1.9k 0.7×	2.0k 0.8×	687 0.3×	2.5k 1.3×	1.2k 0.9×	75	5.0k
Giordano Nicoletti Italy	41	1.7k 0.6×	2.2k 1.0×	1.3k 0.6×	1.5k 0.8×	676 0.5×	140	4.9k

Countries citing papers authored by Xia Bu

Since Specialization

Citations

This map shows the geographic impact of Xia Bu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xia Bu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xia Bu more than expected).

Fields of papers citing papers by Xia Bu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xia Bu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xia Bu. The network helps show where Xia Bu may publish in the future.

Co-authorship network of co-authors of Xia Bu

This figure shows the co-authorship network connecting the top 25 collaborators of Xia Bu. A scholar is included among the top collaborators of Xia Bu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Xia Bu. Xia Bu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Bu, Xia, An Min Wang, Yonghai Li, et al.. (2025). Paneth cells inhibit intestinal stem cell proliferation through the bone morphogenic protein 7 pathway under rotavirus-mediated intestinal injury. World Journal of Gastroenterology. 31(26). 107044–107044.

Bu, Xia, Jun Li, & Hong Zhu. (2025). Glycyrrhizin mediates autophagy through the STAT3/survivin pathway to inhibit proliferation and angiogenesis in hepatoma cells. Cytotechnology. 77(4). 149–149. 1 indexed citations

Hacken, Elisa ten, Johan E. Gustafsson, Kayla Cruz, et al.. (2024). Polyfunctional Effector PD-1+ CD8+ T Cells and M1 Macrophages Promote Immune Checkpoint Blockade Response in Richter Syndrome Mouse Models. Blood. 144(Supplement 1). 761–761. 1 indexed citations

Chaudhri, Apoorvi, Xia Bu, Yunfei Wang, et al.. (2023). The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy. Frontiers in Immunology. 14. 16 indexed citations

Ikegawa, Shuntaro, Haesook T. Kim, Gordon J. Freeman, et al.. (2022). Low Dose IL-2 Therapy in Patients with Chronic Gvhd Induces PD-1+treg That Are Highly Activated, Immune Suppressive, and Proapoptotic. Transplantation and Cellular Therapy. 28(3). S59–S60. 1 indexed citations

Bu, Xia, Vikram R. Juneja, Carol Reynolds, et al.. (2021). Monitoring PD-1 Phosphorylation to Evaluate PD-1 Signaling during Antitumor Immune Responses. Cancer Immunology Research. 9(12). 1465–1475. 11 indexed citations

Dai, Xiaoming, Xia Bu, Yang Gao, et al.. (2021). Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade. Molecular Cell. 81(11). 2317–2331.e6. 160 indexed citations

Rashidian, Mohammad, Martin W. LaFleur, Anushka Dongre, et al.. (2019). Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade. Proceedings of the National Academy of Sciences. 116(34). 16971–16980. 87 indexed citations

Mahoney, Kathleen M., Sachet A. Shukla, Nikolaos Patsoukis, et al.. (2018). A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression. Cancer Immunology Immunotherapy. 68(3). 421–432. 112 indexed citations

10.

Jiang, Peng, Shengqing Gu, Deng Pan, et al.. (2018). Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response. Nature Medicine. 24(10). 1550–1558. 3242 indexed citations breakdown →

11.

Bu, Xia, et al.. (2017). Immune Checkpoint Blockade in Breast Cancer Therapy. Advances in experimental medicine and biology. 1026. 383–402. 27 indexed citations

12.

Zhang, Jinfang, Xia Bu, Haizhen Wang, et al.. (2017). Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance. Nature. 553(7686). 91–95. 736 indexed citations breakdown →

13.

Li, Xiaoyü & Xia Bu. (2017). Progress in Vaccine Therapies for Breast Cancer. Advances in experimental medicine and biology. 1026. 315–330. 14 indexed citations

14.

Jemielity, Stephanie, Ying Chan, Asim A. Ahmed, et al.. (2013). TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine. PLoS Pathogens. 9(3). e1003232–e1003232. 272 indexed citations

15.

Yang, Guang, et al.. (2011). Cell-type-specific regulation of raft-associated Akt signaling. Cell Death and Disease. 2(4). e145–e145. 19 indexed citations

16.

Jiang, Shuxian, Hava Avraham, Shin‐Young Park, et al.. (2005). Process elongation of oligodendrocytes is promoted by the Kelch‐related actin‐binding protein Mayven. Journal of Neurochemistry. 92(5). 1191–1203. 31 indexed citations

17.

Ferland, Russell J., Xiaoyu Li, Janet E. Buhlmann, et al.. (2005). Characterization of Rho-GDIγ and Rho-GDIα mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIγ. Brain Research. 1054(1). 9–21. 9 indexed citations

18.

Bu, Xia, Hava Avraham, Xiaoyu Li, et al.. (2005). Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells. Oncogene. 24(14). 2398–2409. 17 indexed citations

19.

Zhang, Jianmin, Jinping Zhu, Xia Bu, et al.. (2004). Cdc42 and RhoB Activation Are Required for Mannose Receptor-mediated Phagocytosis by Human Alveolar Macrophages. Molecular Biology of the Cell. 16(2). 824–834. 70 indexed citations

20.

Li, Xiaoyu, Xia Bu, Binfeng Lu, et al.. (2002). The Hematopoiesis-Specific GTP-Binding Protein RhoH Is GTPase Deficient and Modulates Activities of Other Rho GTPases by an Inhibitory Function. Molecular and Cellular Biology. 22(4). 1158–1171. 116 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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