Patrick Hwu

33.3k total citations · 10 hit papers
200 papers, 17.4k citations indexed

About

Patrick Hwu is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Patrick Hwu has authored 200 papers receiving a total of 17.4k indexed citations (citations by other indexed papers that have themselves been cited), including 151 papers in Oncology, 80 papers in Immunology and 77 papers in Molecular Biology. Recurrent topics in Patrick Hwu's work include Immunotherapy and Immune Responses (62 papers), CAR-T cell therapy research (62 papers) and Cancer Immunotherapy and Biomarkers (59 papers). Patrick Hwu is often cited by papers focused on Immunotherapy and Immune Responses (62 papers), CAR-T cell therapy research (62 papers) and Cancer Immunotherapy and Biomarkers (59 papers). Patrick Hwu collaborates with scholars based in United States, Australia and Italy. Patrick Hwu's co-authors include Steven A. Rosenberg, Douglas J. Schwartzentruber, Suzanne L. Topalian, James Chih‐Hsin Yang, Richard M. Sherry, Seth M. Steinberg, Leah Haworth, Claudia A. Seipp, Donald E. White and Helen X. Chen and has published in prestigious journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and Journal of Clinical Investigation.

In The Last Decade

Patrick Hwu

195 papers receiving 17.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A Randomized Trial of Bevacizumab, an Anti–Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer

2003 2.1k citations James Chih‐Hsin Yang, Leah Haworth et al. profile →
Chimeric antigen receptor T-cell therapy — assessment and management of toxicities

2017 1.6k citations Patrick Hwu et al. profile →
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

1998 1.5k citations Steven A. Rosenberg, James Chih‐Hsin Yang et al. profile →
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

2003 1.2k citations Giao Q. Phan, James Chih‐Hsin Yang et al. Proceedings of the National Academy of Sciences profile →
A Phase I Study on Adoptive Immunotherapy Using Gene-Modified T Cells for Ovarian Cancer

2006 984 citations Sharon Mavroukakis, James C. Yang et al. Clinical Cancer Research profile →
Randomized Study of High-Dose and Low-Dose Interleukin-2 in Patients With Metastatic Renal Cancer

2003 573 citations James Chih‐Hsin Yang, Richard M. Sherry et al. Journal of Clinical Oncology profile →
Phase I Study of the Intravenous Administration of AttenuatedSalmonella typhimuriumto Patients With Metastatic Melanoma

2002 565 citations John Toso, Vee J. Gill et al. Journal of Clinical Oncology profile →
Regulation of B Cell Differentiation and Plasma Cell Generation by IL-21, a Novel Inducer of Blimp-1 and Bcl-6

2004 534 citations Patrick Hwu et al. profile →
NRAS mutation status is an independent prognostic factor in metastatic melanoma

2011 528 citations Roland L. Bassett, Chaan S. Ng et al. profile →
Challenges and opportunities in cancer immunotherapy: a Society for Immunotherapy of Cancer (SITC) strategic vision

2024 64 citations Leisha A. Emens, Pedro Romero et al. Journal for ImmunoTherapy of Cancer profile →

Peers

Countries citing papers authored by Patrick Hwu

Since Specialization

Citations

This map shows the geographic impact of Patrick Hwu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick Hwu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick Hwu more than expected).

Fields of papers citing papers by Patrick Hwu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick Hwu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick Hwu. The network helps show where Patrick Hwu may publish in the future.

Co-authorship network of co-authors of Patrick Hwu

This figure shows the co-authorship network connecting the top 25 collaborators of Patrick Hwu. A scholar is included among the top collaborators of Patrick Hwu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Patrick Hwu. Patrick Hwu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Preclinical models of melanoma leptomeningeal disease to assess intrathecal checkpoint blockade 2025 ·Scientific Reports ·Renato Guerrieri, Grant M. Fischer, (unknown), Barbara Knighton, (unknown), Courtney W. Hudgens, (unknown), Qianghua Hu, (unknown), Fernando C. L. Carapeto, (unknown), Jason T. Huse, Patrick Hwu, Elizabeth M. Burton, Isabella C. Glitza Oliva, Michael A. Davies, Sherise D. Ferguson	0
2	Integrative Immune Signature of Complementary Circulating and Tumoral Biomarkers Maximizes the Predictive Power of Adjuvant Immunotherapeutic Benefits in High-risk Melanoma 2025 ·Clinical Cancer Research ·Ahmad A. Tarhini, (unknown), Sandra J. Lee, William A. LaFramboise, F. Stephen Hodi, Arivarasan Karunamurthy, (unknown), Dung‐Tsa Chen, Patrick Hwu, Issam El Naqa, Howard Streicher, Vernon K. Sondak, Walter J. Storkus, Lisa H. Butterfield, Timothy I. Shaw, John M. Kirkwood	0
3	Chromatin Remodelers Are Regulators of the Tumor Immune Microenvironment 2024 ·Cancer Research ·Apoorvi Chaudhri, Gregory Lizée, Patrick Hwu, Kunal Rai	7
4	Challenges and opportunities in cancer immunotherapy: a Society for Immunotherapy of Cancer (SITC) strategic vision breakdown → 2024 ·Journal for ImmunoTherapy of Cancer ·Leisha A. Emens, Pedro Romero, Ana C. Anderson, Tullia C. Bruno, Christian M. Capitini, Deborah Collyar, James L. Gulley, Patrick Hwu, Avery D. Posey, Ann W. Silk, Jennifer A. Wargo	64
5	The T Cell Immunoscore as a Reference for Biomarker Development Utilizing Real-World Data from Patients with Advanced Malignancies Treated with Immune Checkpoint Inhibitors 2023 ·Cancers ·(unknown), (unknown), James L. Chen, Aakrosh Ratan, Martin D. McCarter, John D. Carpten, Howard Colman, Alexandra P. Ikeguchi, Igor Puzanov, Susanne M. Arnold, Michelle L. Churchman, Patrick Hwu, José R. Conejo-García, William S. Dalton, George J. Weiner, Issam El Naqa, Ahmad A. Tarhini	5
6	Rethinking the immunotherapy numbers game 2022 ·Journal for ImmunoTherapy of Cancer ·(unknown), Mohammad U. Zahid, Jennifer M. Binning, Bryan Q. Spring, Patrick Hwu, Shari Pilon‐Thomas, Heiko Enderling	12
7	CRISPR-mediated TGFBR2 knockout renders human ovarian cancer tumor-infiltrating lymphocytes resistant to TGF-β signaling 2022 ·Journal for ImmunoTherapy of Cancer ·Samantha M. Fix, Marie‐Andrée Forget, Donastas Sakellariou-Thompson, Yunfei Wang, (unknown), (unknown), Cara Haymaker, Ana Lucía Dominguez, Rafet Başar, (unknown), Sanjay Kumar, Larissa A. Meyer, Patrick Hwu, Chantale Bernatchez, Amir A. Jazaeri	29
8	Perspectives in immunotherapy: meeting report from the immunotherapy bridge (December 2nd–3rd, 2020, Italy) 2021 ·Journal of Translational Medicine ·Paolo A. Ascierto, Carlo Bifulco, Fortunato Ciardiello, Sandra Demaria, Leisha A. Emens, Robert L. Ferris, Silvia C. Formenti, Jérôme Galon, Samir N. Khleif, Tomas Kirchhoff, Jennifer L. McQuade, Kunle Odunsi, Akash Patnaik, Chrystal M. Paulos, Janis M. Taube, John M. Timmerman, Bernard A. Fox, Patrick Hwu, Igor Puzanov	3
9	A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel IL2Rβγ-Biased Cytokine, in Patients with Advanced or Metastatic Solid Tumors 2019 ·Cancer Discovery ·Salah-Eddine Bentebibel, Michael E. Hurwitz, Chantale Bernatchez, Cara Haymaker, Courtney W. Hudgens, Harriet M. Kluger, Michael T. Tetzlaff, Mary Tagliaferri, Jonathan Zalevsky, Ute Hoch, Christie Fanton, Sandra Aung, Patrick Hwu, Brendan D. Curti, Nizar M. Tannir, Mario Sznol, Adi Diab	169
10	Long-term overall survival and prognostic score predicting survival: the IMPACT study in precision medicine 2019 ·Journal of Hematology & Oncology ·Apostolia M. Tsimberidou, David S. Hong, Jennifer J. Wheler, Gerald S. Falchook, Filip Jankú, Aung Naing, Siqing Fu, Sarina A. Piha‐Paul, Carrie Cartwright, Russell R. Broaddus, Graciela M. Nogueras‐González, Patrick Hwu, Razelle Kurzrock	46
11	Induction of NKG2D Ligands on Solid Tumors Requires Tumor-Specific CD8+ T Cells and Histone Acetyltransferases 2017 ·Cancer Immunology Research ·Jiemiao Hu, Chantale Bernatchez, Liangfang Zhang, Xueqing Xia, Eugenie S. Kleinerman, Mien‐Chie Hung, Patrick Hwu, Shulin Li	21
12	Correlation of BRAF Mutation Status in Circulating-Free DNA and Tumor and Association with Clinical Outcome across Four BRAFi and MEKi Clinical Trials 2015 ·Clinical Cancer Research ·Ademi Santiago-Walker, Robert Gagnon, Jolly Mazumdar, Michelle Casey, Georgina V. Long, Dirk Schadendorf, Keith T. Flaherty, Richard Kefford, Axel Hauschild, Patrick Hwu, Patricia Haney, Anne O’Hagan, Jennifer Carver, Vicki Goodman, Jeffrey J. Legos, Anne‐Marie Martin	158
13	Complete Loss of PTEN Protein Expression Correlates with Shorter Time to Brain Metastasis and Survival in Stage IIIB/C Melanoma Patients with BRAF V600 Mutations 2014 ·Clinical Cancer Research ·Amanda D. Bucheit, Guo Chen, Alan Siroy, Michael T. Tetzlaff, Russell R. Broaddus, Denái R. Milton, Patricia S. Fox, Roland L. Bassett, Patrick Hwu, Jeffrey E. Gershenwald, Alexander J. Lazar, Michael A. Davies	109
14	Phase I Study of the Combination of Sorafenib and Temsirolimus in Patients with Metastatic Melanoma 2012 ·Clinical Cancer Research ·Michael A. Davies, Patricia S. Fox, Nicholas E. Papadopoulos, Agop Y. Bedikian, Wen-Jen Hwu, Alexander J. Lazar, Víctor G. Prieto, Kirk S. Culotta, Timothy Madden, Quanyun A. Xu, Sha Huang, Wanleng Deng, Chaan S. Ng, Sanjay Gupta, Wenbin Liu, Janet Dancey, James R. Wright, Roland L. Bassett, Patrick Hwu, Kevin B. Kim	39
15	Phase II Study of the MEK1/MEK2 Inhibitor Trametinib in Patients With Metastatic BRAF -Mutant Cutaneous Melanoma Previously Treated With or Without a BRAF Inhibitor 2012 ·Journal of Clinical Oncology ·Kevin B. Kim, Richard Kefford, Anna C. Pavlick, Jeffrey R. Infante, Antoni Ribas, Jeffrey A. Sosman, Leslie A. Fecher, Michael Millward, Grant A. McArthur, Patrick Hwu, René González, Patrick A. Ott, Georgina V. Long, Olivia Gardner, Danièle Ouellet, Yanmei Xu, Douglas J. DeMarini, Ngocdiep T. Le, Kiran Patel, Karl D. Lewis	356
16	BRAF(V600) Inhibitor GSK2118436 Targeted Inhibition of Mutant BRAF in Cancer Patients Does Not Impair Overall Immune Competency 2012 ·Clinical Cancer Research ·David S. Hong, Luis M. Vence, Gerald S. Falchook, Laszlo Radvanyi, Chengwen Liu, Vicki Goodman, Jeffery J. Legos, (unknown), (unknown), Razelle Kurzrock, Gregory Lizée, Patrick Hwu	82
17	Mast Cells in Tumor Microenvironment Promotes the In Vivo Growth of Pancreatic Ductal Adenocarcinoma 2011 ·Clinical Cancer Research ·David Z. Chang, Ying Ma, Baoan Ji, Huamin Wang, Defeng Deng, Yan Liu, James L. Abbruzzese, Yong‐Jun Liu, Craig D. Logsdon, Patrick Hwu	119
18	Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates 2009 ·Molecular Cancer Therapeutics ·Scott E. Woodman, Jonathan C. Trent, Katherine Stemke‐Hale, Alexander J. Lazar, Sabrina Pricl, Giovanni M. Pavan, Maurizio Fermeglia, Y.N. Vashisht Gopal, Dan Yang, Donald A. Podoloff, Doina Ivan, Kevin B. Kim, Nikolaos G. Papadopoulos, Patrick Hwu, Gordon B. Mills, Michael A. Davies	141
19	Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma breakdown → 2003 ·Proceedings of the National Academy of Sciences ·Giao Q. Phan, James Chih‐Hsin Yang, Richard M. Sherry, Patrick Hwu, Suzanne L. Topalian, Douglas J. Schwartzentruber, Nicholas P. Restifo, Leah Haworth, Claudia A. Seipp, (unknown), Kathleen E. Morton, Sharon Mavroukakis, Paul H. Duray, Seth M. Steinberg, James P. Allison, Thomas A. Davis, Steven A. Rosenberg	1234
20	Phase I Study of the Intravenous Administration of AttenuatedSalmonella typhimuriumto Patients With Metastatic Melanoma breakdown → 2002 ·Journal of Clinical Oncology ·John Toso, Vee J. Gill, Patrick Hwu, Francesco M. Marincola, Nicholas P. Restifo, Douglas J. Schwartzentruber, Richard M. Sherry, Suzanne L. Topalian, James C. Yang, Frida Stock, (unknown), Kathleen E. Morton, Claudia A. Seipp, Leah Haworth, Sharon Mavroukakis, Donald White, Susan MacDonald, John Mao, Mario Sznol, Steven A. Rosenberg	565

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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