Xavier Wittebole

10.6k citations

102 papers · 4.5k indexed · 2 hit papers · h-index 37

Impact in

Critical Care and Intensive Care Medicine top 0.5%
- Intensive Care Unit Cognitive Disorders
Applied Microbiology and Biotechnology top 1%

Papers in ⓘ

Epidemiology 46
- Sepsis Diagnosis and Treatment 35
- Pneumonia and Respiratory Infections 7
Pulmonary and Respiratory Medicine 28
- Respiratory Support and Mechanisms 19

Co-authors: Pierre‐François Laterre (42 shared papers)Steven M. Opal (4 shared papers)Jean‐Louis Vincent (17 shared papers)Sophie De Roock (1 shared paper)Thierry Dugernier (15 shared papers)Yasser Sakr (9 shared papers)Daniel De Backer (4 shared papers)Diego Castanares‐Zapatero (14 shared papers)
Journals: Critical Care (11 papers)Critical Care Medicine (7 papers)Journal of Critical Care (7 papers)Intensive Care Medicine (6 papers)Annals of Intensive Care (5 papers)
Partner nations: Belgium France United States

In The Last Decade

Xavier Wittebole

96 papers receiving 4.4k citations

Hit Papers

align trajectories log scale

Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit 2018 · 306 citations

Peers

Countries citing papers authored by Xavier Wittebole

Since Specialization

Citations

This map shows the geographic impact of Xavier Wittebole's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xavier Wittebole with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xavier Wittebole more than expected).

Fields of papers citing papers by Xavier Wittebole

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xavier Wittebole. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xavier Wittebole. The network helps show where Xavier Wittebole may publish in the future.

Co-authors

The 25 scholars most cited alongside Xavier Wittebole, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Xavier Wittebole Line = papers co-authored together Xavier Wittebole links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 102 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A historical overview of bacteriophage therapy as an alternative to antibiotics for the treatment of bacterial pathogens Virulence ·Xavier Wittebole, Sophie De Roock, Steven M. Opal Hit paper breakdown →	2013	432
2	Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit Open Forum Infectious Diseases ·Yasser Sakr, Ulrich Jaschinski, Xavier Wittebole, Tamás Szakmány, Jeffrey Lipman, Silvio A. Ñamendys‐Silva, Ignacio Martín‐Loeches, Marc Léone, Mary‐Nicoleta Lupu, Jean‐Louis Vincent, (unknown) Hit paper breakdown →	2018	306
3	Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock Critical Care ·Fabio Silvio Taccone, Pierre‐François Laterre, Thierry Dugernier, Herbert Spapen, Isabelle Delattre, Xavier Wittebole, Daniel De Backer, Brice Layeux, Pierre Wallemacq, Jean‐Louis Vincent, Frédérique Jacobs	2010	285
4	The Surviving Sepsis Campaign bundles and outcome: results from the International Multicentre Prevalence Study on Sepsis (the IMPreSS study) Intensive Care Medicine ·Andrew Rhodes, Gary Phillips, Richard Beale, Maurizio Cecconi, Jean‐Daniel Chiche, Daniel De Backer, Jigeeshu Vasishtha Divatia, Bin Du, Laura Evans, Ricard Ferrer, Massimo Girardis, Despoina Koulenti, Flávia Ribeiro Machado, Steven Q. Simpson, Cheng Cheng Tan, Xavier Wittebole, Mitchell M. Levy	2015	242
5	A PILOT-CONTROLLED STUDY OF A POLYMYXIN B-IMMOBILIZED HEMOPERFUSION CARTRIDGE IN PATIENTS WITH SEVERE SEPSIS SECONDARY TO INTRA-ABDOMINAL INFECTION Shock ·Jean‐Louis Vincent, Pierre-Fran ois Laterre, Jonathan Cohen, H. Burchardi, Hajo A. Bruining, Francisco Álvarez-Lerma, Xavier Wittebole, Daniel De Backer, Stephen J. Brett, Dolores Marzo, Haruji Nakamura, Stephanie John	2005	230
6	Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock Critical Care ·Fabio Silvio Taccone, Pierre‐François Laterre, Herbert Spapen, Thierry Dugernier, Isabelle Delattre, Brice Layeux, Daniel De Backer, Xavier Wittebole, Pierre Wallemacq, Jean‐Louis Vincent, Frédérique Jacobs	2010	150
7	Compartmentalization of the Inflammatory Response during Acute Pancreatitis American Journal of Respiratory and Critical Care Medicine ·Thierry Dugernier, Pierre‐François Laterre, Xavier Wittebole, Jean Roeseler, Dominique Latinne, Marc Reynaert, Jérôme Pugin	2003	130
8	Toll-like Receptor 4 Modulation as a Strategy to Treat Sepsis Mediators of Inflammation ·Xavier Wittebole, Diego Castanares‐Zapatero, Pierre‐François Laterre	2010	115
9	Expression and Role of Myeloid-related Protein-14 in Clinical and Experimental Sepsis American Journal of Respiratory and Critical Care Medicine ·Marieke A. D. van Zoelen, Thomas Vogl, Dirk Foell, Suzanne Q. van Veen, J. W. Olivier van Till, Sandrine Florquin, Michael W.T. Tanck, Xavier Wittebole, Pierre‐François Laterre, Marja A. Boermeester, Johannes Roth, Tom van der Poll	2009	112
10	Being Overweight Is Associated With Greater Survival in ICU Patients Critical Care Medicine ·Yasser Sakr, Ilmi Alhussami, Rahul Nanchal, Richard G. Wunderink, Tommaso Pellis, Xavier Wittebole, Ignacio Martín‐Loeches, Bruno François, Marc Léone, Jean‐Louis Vincent	2015	112
11	Recombinant human platelet-activating factor acetylhydrolase for treatment of severe sepsis: Results of a phase III, multicenter, randomized, double-blind, placebo-controlled, clinical trial* Critical Care Medicine ·Steven M. Opal, Pierre‐François Laterre, Edward Abraham, Bruno François, Xavier Wittebole, S. C. Lowry, Jean-François Dhainaut, Brian Warren, Thierry Dugernier, Ángel Crespo López, Miguel Sánchez, Ignace Demeyer, Luis Jáuregui, José A. Lorente, William T. McGee, Konrad Reinhart, S. Kljucar, Sonia Souza, John P. Pribble	2004	103
12	Soluble ST2 plasma concentrations predict mortality in severe sepsis Intensive Care Medicine ·Jacobien J. Hoogerwerf, Michael W.T. Tanck, Marieke A. D. van Zoelen, Xavier Wittebole, Pierre‐François Laterre, Tom van der Poll	2010	100
13	Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP) Intensive Care Medicine ·(unknown), Jean‐Louis Vincent, (unknown), Jean‐Yves Lefrant, Katarzyna Kotfis, Rahul Nanchal, Ignacio Martín‐Loeches, Xavier Wittebole, Samir G. Sakka, Peter Pickkers, Rui P. Moreno, Yasser Sakr	2018	96
14	A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from The Intensive Care Over Nations audit Critical Care ·Esther Peters, Massimo Antonelli, Xavier Wittebole, Rahul Nanchal, Bruno François, Yasser Sakr, Jean‐Louis Vincent, Peter Pickkers	2018	89
15	Lipopolysaccharide‐Binding Protein Serum Levels in Patients with Severe Sepsis Due to Gram‐Positive and Fungal Infections The Journal of Infectious Diseases ·Laurent Blairon, Xavier Wittebole, Pierre‐François Laterre	2003	83
16	Systemic and local high mobility group box 1 concentrations during severe infection Critical Care Medicine ·Marieke A. D. van Zoelen, Pierre‐François Laterre, Suzanne Q. van Veen, J. W. Olivier van Till, Xavier Wittebole, Paul Bresser, Michael W.T. Tanck, Thierry Dugernier, Akitoshi Ishizaka, Marja A. Boermeester, Tom van der Poll	2007	77
17	Recombinant Tissue Factor Pathway Inhibitor in Severe Community-acquired Pneumonia: A Randomized Trial American Journal of Respiratory and Critical Care Medicine ·Richard G. Wunderink, Pierre-François Laterre, Bruno François, D. Perrotin, Antonio Artigas, Luis Otero Vidal, Suzana M Lobo, Jorge San Juan, Sung Chul Hwang, Thierry Dugernier, Steven P. LaRosa, Xavier Wittebole, Jean-François Dhainaut, Christopher J. Doig, Meryl H. Mendelson, Christian Zwingelstein, Guoqin Su, Steven M. Opal	2011	76
18	Worldwide audit of blood transfusion practice in critically ill patients Critical Care ·(unknown), Jean‐Louis Vincent, Ulrich Jaschinski, Xavier Wittebole, Jean‐Yves Lefrant, Stephan M. Jakob, Ghaleb A. Almekhlafi, Tommaso Pellis, Swagata Tripathy, Paolo N. Rubatto Birri, Yasser Sakr	2018	70
19	Nicotine exposure altersin vivohuman responses to endotoxin Clinical & Experimental Immunology ·Xavier Wittebole, Sae J. Hahm, S M Coyle, Ashwini Kumar, Steven E. Calvano, S. F. Lowry	2006	68
20	Temocillin (6 g daily) in critically ill patients: continuous infusion versus three times daily administration Journal of Antimicrobial Chemotherapy ·Pierre-François Laterre, Xavier Wittebole, Sébastien Van de Velde, Anouk E. Muller, Johan W. Mouton, Stéphane Carryn, Paul M. Tulkens, Thierry Dugernier	2014	66

About Xavier Wittebole

Xavier Wittebole is a scholar working on Epidemiology, Pulmonary and Respiratory Medicine, Critical Care and Intensive Care Medicine, Surgery and Emergency Medicine, having authored 102 papers that have together received 4.5k indexed citations. Recurring topics across this work include Sepsis Diagnosis and Treatment (35 papers), Respiratory Support and Mechanisms (19 papers), Intensive Care Unit Cognitive Disorders (15 papers), Nosocomial Infections in ICU (12 papers), Antibiotics Pharmacokinetics and Efficacy (9 papers), Immune Response and Inflammation (8 papers), Pneumonia and Respiratory Infections (7 papers) and Poisoning and overdose treatments (7 papers). The work is most often cited by research in Critical Care and Intensive Care Medicine (768 citations), Applied Microbiology and Biotechnology (207 citations), Molecular Medicine (293 citations), Epidemiology (1.8k citations) and Emergency Medicine (476 citations). Xavier Wittebole has collaborated with scholars based in Belgium, France and United States. Frequent co-authors include Pierre‐François Laterre, Steven M. Opal, Jean‐Louis Vincent, Sophie De Roock, Thierry Dugernier, Yasser Sakr, Daniel De Backer, Diego Castanares‐Zapatero, Philippe Hantson and Ignacio Martín‐Loeches. Their work appears in journals such as Critical Care, Critical Care Medicine, Journal of Critical Care, Intensive Care Medicine and Annals of Intensive Care.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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