Wuyan Chen

2.1k citations

42 papers · 1.5k indexed · h-index 26

Impact in

Clinical Biochemistry top 5%
- Metabolism and Genetic Disorders
Endocrinology, Diabetes and Metabolism top 5%
- Hormonal and reproductive studies

Papers in ⓘ

Molecular Biology 34
- Sexual Differentiation and Disorders 13
- Protein Structure and Dynamics 3
Genetics 15
- Connective tissue disorders research 6
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities 4

Co-authors: Deborah P. Merke (13 shared papers)Nazli B. McDonnell (10 shared papers)Yechun Xu (15 shared papers)Carol Van Ryzin (5 shared papers)Xu Zhi (8 shared papers)Fady Hannah‐Shmouni (2 shared papers)Gabriela P. Finkielstain (3 shared papers)Rachel Morissette (5 shared papers)
Journals: Journal of Medicinal Chemistry (5 papers)The Journal of Clinical Endocrinology & Metabolism (3 papers)European Journal of Medicinal Chemistry (2 papers)Clinical Chemistry (2 papers)Biochemical and Biophysical Research Communications (2 papers)
Partner nations: China United States Israel

In The Last Decade

Wuyan Chen

42 papers receiving 1.5k citations

Peers

Countries citing papers authored by Wuyan Chen

Since Specialization

Citations

This map shows the geographic impact of Wuyan Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wuyan Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wuyan Chen more than expected).

Fields of papers citing papers by Wuyan Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wuyan Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wuyan Chen. The network helps show where Wuyan Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Wuyan Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Wuyan Chen Line = papers co-authored together Wuyan Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 42 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Comprehensive Genetic Analysis of 182 Unrelated Families with Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency The Journal of Clinical Endocrinology & Metabolism ·Gabriela P. Finkielstain, Wuyan Chen, Sneha P. Mehta, Frank K. Fujimura, Reem Hanna, Carol Van Ryzin, Nazli B. McDonnell, Deborah P. Merke	2010	136
2	Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain Journal of Medicinal Chemistry ·Lele Zhao, Danyan Cao, Tiantian Chen, Ying-Qing Wang, Ze‐Hong Miao, Yechun Xu, Wuyan Chen, Xin Wang, Yanlian Li, Zhiyan Du, Bing Xiong, Jian Li, Chunyan Xu, Naixia Zhang, Jianhua He, Jingkang Shen	2013	97
3	Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations Acta Crystallographica Section D Biological Crystallography ·Yechun Xu, Minjun Li, Harry M. Greenblatt, Wuyan Chen, Aviv Paz, Orly Dym, Yoav Peleg, Tiantian Chen, Xu Shen, Jianhua He, Hualiang Jiang, Israel Silman, Joel L. Sussman	2011	86
4	Revisiting the prevalence of nonclassic congenital adrenal hyperplasia in US Ashkenazi Jews and Caucasians Genetics in Medicine ·Fady Hannah‐Shmouni, Rachel Morissette, Ninet Sinaii, Meredith Elman, Toni R. Prezant, Wuyan Chen, Ann E. Pulver, Deborah P. Merke	2017	82
5	Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells Haematologica ·Dang Wu, Wanyan Wang, Wuyan Chen, Fulin Lian, Lang Li, Ying Huang, Yechun Xu, Naixia Zhang, Yinbin Chen, Mingyao Liu, Ruth Nussinov, Feixiong Cheng, Weiqiang Lü, Jin Huang	2018	68
6	Genetics of Congenital Adrenal Hyperplasia Endocrinology and Metabolism Clinics of North America ·Fady Hannah‐Shmouni, Wuyan Chen, Deborah P. Merke	2017	61
7	Junction Site Analysis of Chimeric CYP21A1P/CYP21A2 Genes in 21-Hydroxylase Deficiency Clinical Chemistry ·Wuyan Chen, Xu Zhi, Anne Sullivan, Gabriela P. Finkielstain, Carol Van Ryzin, Deborah P. Merke, Nazli B. McDonnell	2011	61
8	Association of the carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase gene with schizophrenia in the Chinese Han population Biochemical and Biophysical Research Communications ·Yonglan Zheng, Huafang Li, Wei Qin, Wuyan Chen, Yun Duan, Yue Xiao, Chao Li, Jing Zhang, Xingwang Li, Guoyin Feng, Lin He	2005	57
9	Significant Association Between the Genetic Variations in the 5′ End of the N-Methyl-D-Aspartate Receptor Subunit Gene GRIN1 and Schizophrenia Biological Psychiatry ·Xinzhi Zhao, Hongfei Li, Yongyong Shi, Rongbiao Tang, Wuyan Chen, Jixia Liu, Guoyin Feng, Jianguo Shi, Lijuan Yan, Huijun Liu, Lin He	2006	53
10	Tenascin-X Haploinsufficiency Associated with Ehlers-Danlos Syndrome in Patients with Congenital Adrenal Hyperplasia The Journal of Clinical Endocrinology & Metabolism ·Deborah P. Merke, Wuyan Chen, Rachel Morissette, Xu Zhi, Carol Van Ryzin, Vandana Sachdev, Hwaida Hannoush, Sujata M. Shanbhag, Ana Acevedo, Miki Nishitani, Andrew E. Arai, Nazli B. McDonnell	2013	52
11	Phenotypic profiling of parents with cryptic nonclassic congenital adrenal hyperplasia: findings in 145 unrelated families European Journal of Endocrinology ·R. Nandagopal, Ninet Sinaii, Nilo A. Avila, Carol Van Ryzin, Wuyan Chen, Gabriela P. Finkielstain, Sneha P. Mehta, Nazli B. McDonnell, Deborah P. Merke	2011	51
12	Broadening the Spectrum of Ehlers Danlos Syndrome in Patients With Congenital Adrenal Hyperplasia The Journal of Clinical Endocrinology & Metabolism ·Rachel Morissette, Wuyan Chen, Ashley F. Perritt, Jennifer L. Dreiling, Andrew E. Arai, Vandana Sachdev, Hwaida Hannoush, Ashwini Mallappa, Xu Zhi, Nazli B. McDonnell, Martha Quezado, Deborah P. Merke	2015	47
13	Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent Journal of Medicinal Chemistry ·Xianglei Zhang, Guangyu Dong, Heng Li, Wuyan Chen, Jian Li, Chunlan Feng, Zhanni Gu, Fenghua Zhu, Rui Zhang, Minjun Li, Wei Tang, Hong Liu, Yechun Xu	2019	45
14	No association between the promoter variants of tumor necrosis factor alpha (TNF-α) and schizophrenia in Chinese Han population Neuroscience Letters ·Shiwei Duan, Yifeng Xu, Wuyan Chen, Zhuangjun Liu, Tingwei Guo, Jianjun Gao, Bian Li, Yonglan Zhen, Xiuxia Li, Xiaoju Zhang, Yuxi Pan, Niufan Gu, Guoyin Feng, Lin He	2004	39
15	Cyanobacterial Peptides as a Prototype for the Design of Potent β-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases Journal of Medicinal Chemistry ·Yanxia Liu, Wei Zhang, Li Li, Lilibeth A. Salvador, Tiantian Chen, Wuyan Chen, Kevin M. Felsenstein, Thomas B. Ladd, Ashleigh Price, Todd E. Golde, Jianhua He, Yechun Xu, Yingxia Li, Hendrik Luesch	2012	39
16	A case–control study provides evidence of association for a functional polymorphism −197C/G in XBP1 to schizophrenia and suggests a sex-dependent effect Biochemical and Biophysical Research Communications ·Wuyan Chen, Shiwei Duan, Jian Zhou, Yun Sun, Yonglan Zheng, Niufan Gu, Guoyin Feng, Lin He	2004	38
17	Transforming Growth Factor-β and Inflammation in Vascular (Type IV) Ehlers–Danlos Syndrome Circulation Cardiovascular Genetics ·Rachel Morissette, Florian Schoenhoff, Xu Zhi, David Shilane, Benjamin F. Griswold, Wuyan Chen, Jiandong Yang, Jie Zhu, Justyna Fert‐Bober, Leslie Sloper, Jason Lehman, Natalie Commins, Jennifer E. Van Eyk, Nazli B. McDonnell	2014	37
18	A Dynamic View of ATP-coupled Functioning Cycle of Hsp90 N-terminal Domain Scientific Reports ·Huaqun Zhang, Chen Zhou, Wuyan Chen, Yechun Xu, Yanhong Shi, Yi Wen, Naixia Zhang	2015	35
19	Comprehensive Mutation Analysis of the CYP21A2 Gene Journal of Molecular Diagnostics ·Xu Zhi, Wuyan Chen, Deborah P. Merke, Nazli B. McDonnell	2013	34
20	Design, synthesis and biological evaluation of tasiamide B derivatives as BACE1 inhibitors Bioorganic & Medicinal Chemistry ·Jian Liu, Wuyan Chen, Yechun Xu, Sumei Ren, Wei Zhang, Yingxia Li	2015	32

About Wuyan Chen

Wuyan Chen is a scholar working on Molecular Biology, Genetics, Computational Theory and Mathematics, Pharmacology and Endocrinology, Diabetes and Metabolism, having authored 42 papers that have together received 1.5k indexed citations. Recurring topics across this work include Sexual Differentiation and Disorders (13 papers), Computational Drug Discovery Methods (8 papers), Connective tissue disorders research (6 papers), Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities (4 papers), Urological Disorders and Treatments (4 papers), Cholinesterase and Neurodegenerative Diseases (4 papers), Alzheimer's disease research and treatments (3 papers) and Protein Structure and Dynamics (3 papers). The work is most often cited by research in Clinical Biochemistry (143 citations), Endocrinology, Diabetes and Metabolism (336 citations), Biological Psychiatry (44 citations), Urology (111 citations) and Molecular Biology (1.1k citations). Wuyan Chen has collaborated with scholars based in China, United States and Israel. Frequent co-authors include Deborah P. Merke, Nazli B. McDonnell, Yechun Xu, Carol Van Ryzin, Xu Zhi, Fady Hannah‐Shmouni, Gabriela P. Finkielstain, Rachel Morissette, Tiantian Chen and Jianhua He. Their work appears in journals such as Journal of Medicinal Chemistry, The Journal of Clinical Endocrinology & Metabolism, European Journal of Medicinal Chemistry, Clinical Chemistry and Biochemical and Biophysical Research Communications.

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