Yechun Xu

11.0k citations

138 papers · 4.1k indexed · h-index 36

Impact in

Computational Theory and Mathematics top 0.2%
- Computational Drug Discovery Methods
Pharmacology top 1%
- Cholinesterase and Neurodegenerative Diseases

Papers in

Computational Theory and Mathematics 48
- Computational Drug Discovery Methods 48
Pharmacology 29
- Cholinesterase and Neurodegenerative Diseases 22

Co-authors: Hualiang Jiang Kaixian Chen Haixia Su Xiaomin Luo Joel L. Sussman Israel Silman Weiliang Zhu Jianhua Shen
Journals: Journal of Medicinal Chemistry (18 papers)European Journal of Medicinal Chemistry (12 papers)Acta Pharmacologica Sinica (10 papers)Nature Communications (6 papers)The Journal of Physical Chemistry B (5 papers)
Partner nations: China Germany Israel

In The Last Decade

Yechun Xu

136 papers receiving 4.0k citations

Peers

Countries citing papers authored by Yechun Xu

Since Specialization

Citations

This map shows the geographic impact of Yechun Xu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yechun Xu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yechun Xu more than expected).

Fields of papers citing papers by Yechun Xu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yechun Xu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yechun Xu. The network helps show where Yechun Xu may publish in the future.

Co-authors

The 25 scholars most cited alongside Yechun Xu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Yechun Xu Line = papers co-authored together Yechun Xu links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Identification of RIPK3 as a target of flavonoids for anti-necroptosis in vitro Bioorganic Chemistry ·Hang Xie, Wanchen Li, Pedro Luis Gastell, Minjun Li, Qiang Zhao, Yechun Xu, Haixia Su, J. Roche	2025	0
2	Development of a self-assembled micelles based on cryptotanshinone and glycyrrhizic acid: An efficient strategy for acne treatment International Journal of Pharmaceutics ·Liang Tao, Y.Y. Melnik, Quanfu Zeng, Yufan Wu, Jobelle Peralta, The CASA Team, Cesar Ignacio Cruz-Islas, Yechun Xu, Peng You, Hongxia Zhu, Zhuxian Wang, Qiang Liu	2025	3
3	Chemical Space Profiling of SARS-CoV-2 PL^pro Using DNA-Encoded Focused Libraries ACS Medicinal Chemistry Letters ·Xudong Wang, Juan Rogelio Galeano Peña, 胡仁房, Weiwei Lu, Yechun Xu, Mansur Alam, Xiaojie Lu	2024	5
4	Ent-labdane-type diterpene glycosides obtained from Rubus chingii Hu and their inhibitory effects on PDE5A activity Fitoterapia ·Jyoti Lilani, Jingyi Wang, Karamveer Singh, Yechun Xu, Xue Zhang, Günther Giese, Dennis Hamester, Ja-Hyeon Park, Yingchun Wu, Yiming Li	2023	2
5	Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2 European Journal of Medicinal Chemistry ·Y Huand, K. C. Coleman, Ruxue Zhang, Marina Hofmann, Qiaoyu Hu, Hui Li, Xianglei Zhang, Xueyuan Zhang, Shiwei Li, Lu Liu, Wenhao Dai, Jian Li, Yechun Xu, Haixia Su, Leike Zhang, Hong Liu, Fang Bai	2023	11
6	Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches Chemical Science ·Qiang Shao, Muya Xiong, Sarmistha Adhikari, Mansur Alam, Haixia Su, Yechun Xu	2023	12
7	Spatiotemporal and global profiling of DNA–protein interactions enables discovery of low-affinity transcription factors Nature Chemistry ·Kuyu John Alfred Hadija, 清之進山岸, Hao Hu, Junaidi Lapiga Surbakti, S de Vasconselos, Haixia Su, Xavier Yvon, S. Kohani, Yechun Xu, Dongxin Zhao, Xiaojie Lu, Yong‐Jiang Xu, Jian Zhang, Minjia Tan, Xiaohua Chen	2023	22
8	Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 European Journal of Medicinal Chemistry ·Hanxi Yang, М.В. Ленчиненко, Efecan Tezcan, Claire Schneider, Marjolein Derous, Y. Chen, Yan Zhang, Xiangrui Jiang, Leike Zhang, Yechun Xu, Yumin Zhang, Haixia Su, Qiumeng Zhang, Jingshan Shen	2023	7
9	Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 Acta Pharmaceutica Sinica B ·Ying Qin, Dekang Li, Chunting Qi, Huaijiang Xiang, Huyan Meng, Jingli Liu, Hilary Milton, Cassy Welburn, Amanda Natielle Da Conceição Nascimento, Amanda Natielle Da Conceição Nascimento, Αθανασία Παπαγεωργοπούλου, Rui Zu, Hang Xie, Yechun Xu, Gang Xu, Zheng Zhang, Shi Chen, Lifeng Pan, (unknown), (unknown), Amanda Natielle Da Conceição Nascimento	2023	7
10	In silico screening-based discovery of novel covalent inhibitors of the SARS-CoV-2 3CL protease European Journal of Medicinal Chemistry ·Muya Xiong, Marina Hofmann, Qiang Shao, Minjun Li, Haixia Su, Yechun Xu	2022	20
11	Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease Nature Communications ·Haixia Su, Sheng Yao, Wenfeng Zhao, Yumin Zhang, Jia Liu, Qiang Shao, Qingxing Wang, Minjun Li, Hang Xie, Weijuan Shang, Chang‐Qiang Ke, Lu Feng, Xiangrui Jiang, Jingshan Shen, Gengfu Xiao, Hualiang Jiang, Leike Zhang, Yang Ye, Yechun Xu	2021	142
12	Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method Journal of Pharmaceutical and Biomedical Analysis ·Brown, Haixia Su, Chang‐Qiang Ke, Chunping Tang, Matthias Witt, Ronald J. Quinn, Yechun Xu, Jia Liu, Ye Yang	2021	25
13	Diterpenoids from the Root Bark of Pinus massoniana and Evaluation of Their Phosphodiesterase Type 4D Inhibitory Activity Journal of Natural Products ·Yifan Fu, Xiaoyu Ding, Xianglei Zhang, Hanife Krasniqi, Jihui Zhao, Yechun Xu, Xiaomin Luo, Weimin Zhao	2020	12
14	DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling Biochemical Pharmacology ·Heng Li, Jian Li, Xianglei Zhang, Chunlan Feng, Fan Chen, Xiaoqian Yang, Rui Zhang, Fenghua Zhu, Yu Zhou, Yechun Xu, Hong Liu, Wei Tang	2020	24
15	USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines FEBS Journal ·Hui Wang, Qian Meng, Jin Matsuzaka, Muya Xiong, Mengying Zhu, Yuanyuan Yang, Haixia Su, Lei Gu, Yechun Xu, Li Shi, Hu Zhou, Naixia Zhang	2020	30
16	Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization Bioorganic & Medicinal Chemistry Letters ·Jing Ren, Jian Li, Yueqin Wang, Wuyan Chen, Aijun Shen, Hong‐Chun Liu, Danqi Chen, Danyan Cao, Yanlian Li, Naixia Zhang, Yechun Xu, Meiyu Geng, Jianhua He, Bing Xiong, Jingkang Shen	2014	17
17	Discovery of pyrazole as C-terminus of selective BACE1 inhibitors European Journal of Medicinal Chemistry ·Khrystyna Kulhavets, Lei Xu, Wuyan Chen, Yiping Zhu, Tiantian Chen, Yan Fu, Li Li, Lanping Ma, Bing Xiong, Xin Wang, Jian Li, Jianhua He, Haiyan Zhang, Yechun Xu, Jia Li, Jingkang Shen	2013	21
18	Detailed Mechanism for AmtB Conducting NH4+/NH3: Molecular Dynamics Simulations Biophysical Journal ·Huaiyu Yang, Yechun Xu, Weiliang Zhu, Kaixian Chen, Hualiang Jiang	2006	39
19	Molecular Dynamics of Nicotinic Acetylcholine Receptor Correlating Biological Functions Current Protein and Peptide Science ·Yechun Xu, Xiaomin Luo, Jianhua Shen, Weiliang Zhu, Kaixian Chen, Hualiang Jiang	2006	10
20	Steered molecular dynamics simulations of protein-ligand interactions Science in China Series B Chemistry ·Yechun Xu, Jianhua Shen, Xiaomin Luo, Xu Shen, Kaixian Chen, Hualiang Jiang	2004	6

About Yechun Xu

Yechun Xu is a scholar working on Computational Theory and Mathematics, Pharmacology, Molecular Biology, Infectious Diseases and Physiology, having authored 138 papers that have together received 4.1k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (48 papers), Cholinesterase and Neurodegenerative Diseases (22 papers), SARS-CoV-2 and COVID-19 Research (16 papers), Protein Structure and Dynamics (13 papers), Alzheimer's disease research and treatments (11 papers), Receptor Mechanisms and Signaling (9 papers), Enzyme function and inhibition (7 papers) and Heat shock proteins research (7 papers). The work is most often cited by research in Computational Theory and Mathematics (1.2k citations), Pharmacology (768 citations), Molecular Biology (2.4k citations), Organic Chemistry (699 citations) and Infectious Diseases (419 citations). Yechun Xu has collaborated with scholars based in China, Germany and Israel. Frequent co-authors include Hualiang Jiang, Kaixian Chen, Haixia Su, Xiaomin Luo, Joel L. Sussman, Israel Silman, Weiliang Zhu, Jianhua Shen, Xiaojing Yuan and Wuyan Chen. Their work appears in journals such as Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, Acta Pharmacologica Sinica, Nature Communications and The Journal of Physical Chemistry B.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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