Chao‐Kai Chou

8.2k total citations · 3 hit papers
77 papers, 5.2k citations indexed

About

Chao‐Kai Chou is a scholar working on Molecular Biology, Oncology and Biomedical Engineering. According to data from OpenAlex, Chao‐Kai Chou has authored 77 papers receiving a total of 5.2k indexed citations (citations by other indexed papers that have themselves been cited), including 36 papers in Molecular Biology, 17 papers in Oncology and 14 papers in Biomedical Engineering. Recurrent topics in Chao‐Kai Chou's work include Microfluidic and Capillary Electrophoresis Applications (7 papers), Cancer-related Molecular Pathways (6 papers) and Advanced Biosensing Techniques and Applications (6 papers). Chao‐Kai Chou is often cited by papers focused on Microfluidic and Capillary Electrophoresis Applications (7 papers), Cancer-related Molecular Pathways (6 papers) and Advanced Biosensing Techniques and Applications (6 papers). Chao‐Kai Chou collaborates with scholars based in Taiwan, United States and China. Chao‐Kai Chou's co-authors include Mien‐Chie Hung, O M Rosen, Roberto Gherzi, David Russell, Hsiao‐Sheng Liu, Ping‐Hung Chen, Ming‐Shiou Jan, Jung-Mao Hsu, Weiya Xia and Jennifer L. Hsu and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Chao‐Kai Chou

75 papers receiving 5.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression

2017 768 citations Shiping Jiao, Weiya Xia et al. Clinical Cancer Research profile →
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.

1987 560 citations Chao‐Kai Chou et al. profile →
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy

2021 405 citations Meisi Yan, Jung-Mao Hsu et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Chao‐Kai Chou Taiwan	29	2.8k	1.5k	937	450	429	77	5.2k
Anskar Y.H. Leung Hong Kong	33	2.9k 1.0×	1.3k 0.8×	1.1k 1.2×	284 0.6×	358 0.8×	112	5.5k
Silvia Bruno Italy	32	2.9k 1.0×	1.1k 0.7×	1.0k 1.1×	349 0.8×	304 0.7×	105	5.2k
Leonard Liebes United States	39	2.5k 0.9×	2.1k 1.4×	1.2k 1.3×	335 0.7×	426 1.0×	129	6.2k
Bharat Joshi United States	42	2.8k 1.0×	1.1k 0.7×	1.6k 1.8×	309 0.7×	481 1.1×	109	5.5k
Richard Vandlen United States	38	3.9k 1.4×	2.3k 1.5×	881 0.9×	407 0.9×	615 1.4×	76	7.4k
Peng Guo China	42	3.3k 1.2×	1.0k 0.7×	1000 1.1×	363 0.8×	355 0.8×	144	5.7k
Shinya Oishi Japan	54	3.5k 1.2×	1.3k 0.8×	999 1.1×	193 0.4×	300 0.7×	292	9.7k
Caius G. Radu United States	44	3.0k 1.1×	1.5k 1.0×	2.0k 2.1×	261 0.6×	315 0.7×	127	6.4k
Kun Cheng United States	36	2.5k 0.9×	872 0.6×	506 0.5×	481 1.1×	395 0.9×	102	4.4k
Lei Yao China	42	3.2k 1.1×	1.6k 1.1×	1.3k 1.4×	367 0.8×	430 1.0×	151	6.5k

Countries citing papers authored by Chao‐Kai Chou

Since Specialization

Citations

This map shows the geographic impact of Chao‐Kai Chou's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chao‐Kai Chou with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chao‐Kai Chou more than expected).

Fields of papers citing papers by Chao‐Kai Chou

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chao‐Kai Chou. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chao‐Kai Chou. The network helps show where Chao‐Kai Chou may publish in the future.

Co-authorship network of co-authors of Chao‐Kai Chou

This figure shows the co-authorship network connecting the top 25 collaborators of Chao‐Kai Chou. A scholar is included among the top collaborators of Chao‐Kai Chou based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Chao‐Kai Chou. Chao‐Kai Chou is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Norris, Alexis L., et al.. (2024). Impact of sunitinib resistance on clear cell renal cell carcinoma therapeutic sensitivity in vitro. Cell Cycle. 23(1). 43–55. 2 indexed citations

Norris, Alexis L., Chao‐Kai Chou, Wells W. Wu, et al.. (2023). Extended Opioid Exposure Modulates the Molecular Metabolism of Clear Cell Renal Cell Carcinoma. Life. 13(5). 1196–1196.

Little, Jessica S, Miranda S. Oakley, Anna R. Thorner, et al.. (2023). Immune Control in Repeated Babesia microti Infection in a Patient With B-Cell Deficiency. Open Forum Infectious Diseases. 11(1). ofad568–ofad568. 3 indexed citations

Liu, Shufeng, Charles B. Stauft, Prabhuanand Selvaraj, et al.. (2022). Intranasal delivery of a rationally attenuated SARS-CoV-2 is immunogenic and protective in Syrian hamsters. Nature Communications. 13(1). 6792–6792. 11 indexed citations

Liu, Yen‐Liang, Chao‐Kai Chou, Cong Liu, et al.. (2019). Assessing metastatic potential of breast cancer cells based on EGFR dynamics. Scientific Reports. 9(1). 3395–3395. 47 indexed citations

Lee, Heng‐Huan, Ying‐Nai Wang, Weiya Xia, et al.. (2019). Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy. Cancer Cell. 36(2). 168–178.e4. 282 indexed citations

Jiao, Shiping, Weiya Xia, Hirohito Yamaguchi, et al.. (2017). PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression. Clinical Cancer Research. 23(14). 3711–3720. 768 indexed citations breakdown →

Perillo, Evan P., Yen‐Liang Liu, Cong Liu, et al.. (2015). Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination. Nature Communications. 6(1). 7874–7874. 72 indexed citations

Chou, Chao‐Kai, Heng‐Huan Lee, Chun‐Te Chen, et al.. (2014). mMAPS: A Flow-Proteometric Technique to Analyze Protein-Protein Interactions in Individual Signaling Complexes. Science Signaling. 7(315). rs1–rs1. 7 indexed citations

10.

Lee, Heng‐Huan, Frank J. Lowery, Yekaterina B. Khotskaya, et al.. (2013). Inhibition of Type I Insulin-Like Growth Factor Receptor Signaling Attenuates the Development of Breast Cancer Brain Metastasis. PLoS ONE. 8(9). e73406–e73406. 29 indexed citations

11.

Hsu, Jung-Mao, Chun‐Te Chen, Chao‐Kai Chou, et al.. (2011). Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nature Cell Biology. 13(2). 174–181. 195 indexed citations

12.

Cheng, Xiaoyun, Weiya Xia, Jer-Yen Yang, et al.. (2010). Activation of Murine Double Minute 2 by Akt in Mammary Epithelium Delays Mammary Involution and Accelerates Mammary Tumorigenesis. Cancer Research. 70(19). 7684–7689. 16 indexed citations

13.

Hong, Sungmin, Ying‐Nai Wang, Hirohito Yamaguchi, et al.. (2010). Measurement of Protein 53 Diffusion Coefficient in Live HeLa Cells Using Raster Image Correlation Spectroscopy (RICS). Europe PMC (PubMed Central). 1(1). 31–36. 7 indexed citations

14.

Chou, Chao‐Kai, Nan Jing, Hirohito Yamaguchi, et al.. (2010). High speed digital protein interaction analysis using microfluidic single molecule detection system. Lab on a Chip. 10(14). 1793–1793. 9 indexed citations

15.

Yen, Chia-Jui, Julie Izzo, Dung‐Fang Lee, et al.. (2008). Bile Acid Exposure Up-regulates Tuberous Sclerosis Complex 1/Mammalian Target of Rapamycin Pathway in Barrett's-Associated Esophageal Adenocarcinoma. Cancer Research. 68(8). 2632–2640. 49 indexed citations

16.

Chou, Chao‐Kai, et al.. (2005). Dominant-negative Rac1 suppresses Ras-induced apoptosis possibly through activation of NFκB in Ha-ras oncogene-transformed NIH/3T3 cells. Life Sciences. 78(16). 1823–1829. 6 indexed citations

17.

Hsu, W-M, et al.. (2004). Impact of stereopsis on quality of life. Eye. 19(5). 540–545. 22 indexed citations

18.

Chou, Chao‐Kai, et al.. (2003). Identifying the factors and signal pathways necessary for anchorage-independent growth of Ha-ras oncogene-transformed NIH/3T3 cells. Life Sciences. 73(10). 1265–1274. 5 indexed citations

19.

Hu, Cheng, H C Hsu, Ah Kau Ng, et al.. (1989). Expression of class I and class II major histocompatibility antigens on human hepatocellular carcinoma.. Journal of Clinical Investigation. 83(2). 421–429. 31 indexed citations

20.

Chou, Chao‐Kai, L.‐T. Ho, L P Ting, et al.. (1987). Selective suppression of insulin-induced proliferation of cultured human hepatoma cells by somatostatin.. Journal of Clinical Investigation. 79(1). 175–178. 46 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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