Chao‐Kai Chou

8.2k citations

77 papers · 5.2k indexed · 3 hit papers · h-index 29

Molecular Biology top 2%
Oncology top 2%
Immunology top 2%
Surgery top 10%
Epidemiology top 10%

Co-authors: Mien‐Chie Hung O M Rosen Roberto Gherzi David Russell Hsiao‐Sheng Liu Ping‐Hung Chen Ming‐Shiou Jan Jung-Mao Hsu
Topics: Microfluidic and Capillary Electrophoresis Applications (7 papers)Cancer-related Molecular Pathways (6 papers)Advanced Biosensing Techniques and Applications (6 papers)
Cited by: Oncology Immunology Molecular Biology
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Journal of Clinical Investigation
Partner nations: Taiwan United States China

In The Last Decade

Chao‐Kai Chou

75 papers receiving 5.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression

2017 768 citations Shiping Jiao, Weiya Xia et al. Clinical Cancer Research profile →
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.

1987 560 citations Chao‐Kai Chou et al. profile →
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy

2021 405 citations Meisi Yan, Jung-Mao Hsu et al. Nature Communications profile →

Peers

Countries citing papers authored by Chao‐Kai Chou

Since Specialization

Citations

This map shows the geographic impact of Chao‐Kai Chou's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chao‐Kai Chou with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chao‐Kai Chou more than expected).

Fields of papers citing papers by Chao‐Kai Chou

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chao‐Kai Chou. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chao‐Kai Chou. The network helps show where Chao‐Kai Chou may publish in the future.

Co-authorship network of co-authors of Chao‐Kai Chou

This figure shows the co-authorship network connecting the top 25 collaborators of Chao‐Kai Chou. A scholar is included among the top collaborators of Chao‐Kai Chou based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Chao‐Kai Chou. Chao‐Kai Chou is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Impact of sunitinib resistance on clear cell renal cell carcinoma therapeutic sensitivity in vitro 2024 ·Cell Cycle ·(unknown),(unknown),(unknown),Alexis L. Norris,Chao‐Kai Chou,Wells W. Wu,Rong‐Fong Shen,Carole Sourbier	2
2	Extended Opioid Exposure Modulates the Molecular Metabolism of Clear Cell Renal Cell Carcinoma 2023 ·Life ·(unknown),(unknown),Alexis L. Norris,Chao‐Kai Chou,Wells W. Wu,Rong‐Fong Shen,Jacob Greenberg,L. Spencer Krane,Carole Sourbier	0
3	Immune Control in Repeated Babesia microti Infection in a Patient With B-Cell Deficiency 2023 ·Open Forum Infectious Diseases ·Jessica S Little,Miranda S. Oakley,Anna R. Thorner,(unknown),Victoria Majam,(unknown),Lewis A. Novack,(unknown),(unknown),Chao‐Kai Chou,(unknown),Robert J. Soiffer,Peter J. Krause,Lindsey R. Baden,Sanjai Kumar	3
4	Intranasal delivery of a rationally attenuated SARS-CoV-2 is immunogenic and protective in Syrian hamsters 2022 ·Nature Communications ·Shufeng Liu,Charles B. Stauft,Prabhuanand Selvaraj,Prabha Chandrasekaran,Felice D’Agnillo,Chao‐Kai Chou,Wells W. Wu,Christopher Z. Lien,Clement A. Meseda,(unknown),Matthew F. Starost,Jerry P. Weir,Tony T. Wang	11
5	Assessing metastatic potential of breast cancer cells based on EGFR dynamics 2019 ·Scientific Reports ·Yen‐Liang Liu,Chao‐Kai Chou,(unknown),(unknown),(unknown),(unknown),Cong Liu,Evan P. Perillo,Yu‐An Chen,(unknown),Hannah Horng,(unknown),Trung D. Nguyen,Thomas E. Yankeelov,Mien‐Chie Hung,Andrew K. Dunn,Hsin‐Chih Yeh	47
6	Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy 2019 ·Cancer Cell ·Heng‐Huan Lee,Ying‐Nai Wang,Weiya Xia,Chia‐Hung Chen,Kun-Ming Rau,Leiguang Ye,Yongkun Wei,Chao‐Kai Chou,Shao‐Chun Wang,Meisi Yan,Chih‐Yen Tu,Te‐Chun Hsia,Shu‐Fen Chiang,K. S. Clifford Chao,Ignacio I. Wistuba,Jennifer L. Hsu,Gabriel N. Hortobágyi,Mien‐Chie Hung	282
7	PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppressionbreakdown → 2017 ·Clinical Cancer Research ·Shiping Jiao,Weiya Xia,Hirohito Yamaguchi,Yongkun Wei,Mei‐Kuang Chen,Jung-Mao Hsu,Jennifer L. Hsu,Wen-Hsuan Yu,Yi Du,Heng‐Huan Lee,Chia‐Wei Li,Chao‐Kai Chou,Seung-Oe Lim,Sam S. Chang,Jennifer K. Litton,Banu Arun,Gabriel N. Hortobágyi,Mien‐Chie Hung	768
8	Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination 2015 ·Nature Communications ·Evan P. Perillo,Yen‐Liang Liu,(unknown),Cong Liu,Chao‐Kai Chou,Mien‐Chie Hung,Hsin‐Chih Yeh,Andrew K. Dunn	72
9	mMAPS: A Flow-Proteometric Technique to Analyze Protein-Protein Interactions in Individual Signaling Complexes 2014 ·Science Signaling ·Chao‐Kai Chou,Heng‐Huan Lee,(unknown),Chun‐Te Chen,Jung-Mao Hsu,Hirohito Yamaguchi,Ying‐Nai Wang,(unknown),(unknown),Jennifer L. Hsu,(unknown),Jun Kameoka,Mien‐Chie Hung	7
10	Inhibition of Type I Insulin-Like Growth Factor Receptor Signaling Attenuates the Development of Breast Cancer Brain Metastasis 2013 ·PLoS ONE ·(unknown),Heng‐Huan Lee,Frank J. Lowery,Yekaterina B. Khotskaya,Weiya Xia,Chenyu Zhang,(unknown),Chao‐Kai Chou,Patricia S. Steeg,Dihua Yu,Mien‐Chie Hung	29
11	Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation 2011 ·Nature Cell Biology ·Jung-Mao Hsu,Chun‐Te Chen,Chao‐Kai Chou,Hsu-Ping Kuo,Long‐Yuan Li,Chun-Yi Lin,Hong-Jen Lee,Ying‐Nai Wang,Mo Liu,Hsin-Wei Liao,Bin Shi,Chien‐Chen Lai,Mark T. Bedford,Chang‐Hai Tsai,Mien‐Chie Hung	195
12	Activation of Murine Double Minute 2 by Akt in Mammary Epithelium Delays Mammary Involution and Accelerates Mammary Tumorigenesis 2010 ·Cancer Research ·Xiaoyun Cheng,Weiya Xia,Jer-Yen Yang,Jennifer L. Hsu,Jing-Yu Lang,Chao‐Kai Chou,Yi Du,Hui-Lung Sun,Shannon L. Wyszomierski,Gordon B. Mills,William J. Muller,Dihua Yu,Mien‐Chie Hung	16
13	Measurement of Protein 53 Diffusion Coefficient in Live HeLa Cells Using Raster Image Correlation Spectroscopy (RICS) 2010 ·Journal of Biomaterials and Nanobiotechnology ·Sungmin Hong,Ying‐Nai Wang,Hirohito Yamaguchi,(unknown),Chao‐Kai Chou,(unknown),Mien‐Chie Hung,Jun Kameoka	7
14	High speed digital protein interaction analysis using microfluidic single molecule detection system 2010 ·Lab on a Chip ·Chao‐Kai Chou,Nan Jing,Hirohito Yamaguchi,(unknown),Heng‐Huan Lee,Chun‐Te Chen,Ying‐Nai Wang,Sungmin Hong,C. B. Su,Jun Kameoka,Mien‐Chie Hung	9
15	Bile Acid Exposure Up-regulates Tuberous Sclerosis Complex 1/Mammalian Target of Rapamycin Pathway in Barrett's-Associated Esophageal Adenocarcinoma 2008 ·Cancer Research ·Chia-Jui Yen,Julie Izzo,Dung‐Fang Lee,Sushovan Guha,Yongkun Wei,Tsung‐Teh Wu,Chun‐Te Chen,Hsu-Ping Kuo,Jung-Mao Hsu,Hui-Lung Sun,Chao‐Kai Chou,Navtej Buttar,Kenneth K. Wang,Peng Huang,Jaffer A. Ajani,Mien‐Chie Hung	49
16	Dominant-negative Rac1 suppresses Ras-induced apoptosis possibly through activation of NFκB in Ha-ras oncogene-transformed NIH/3T3 cells 2005 ·Life Sciences ·Chao‐Kai Chou,(unknown),(unknown),Guan-Cheng Huang,(unknown),(unknown),Hsiao‐Sheng Liu	6
17	Impact of stereopsis on quality of life 2004 ·Eye ·(unknown),W-M Hsu,Chao‐Kai Chou,(unknown),Pesus Chou	22
18	Identifying the factors and signal pathways necessary for anchorage-independent growth of Ha-ras oncogene-transformed NIH/3T3 cells 2003 ·Life Sciences ·(unknown),(unknown),Chao‐Kai Chou,Nan-Haw Chow,Tzeng‐Horng Leu,Hsiao‐Sheng Liu	5
19	Expression of class I and class II major histocompatibility antigens on human hepatocellular carcinoma. 1989 ·Journal of Clinical Investigation ·(unknown),Cheng Hu,H C Hsu,Ah Kau Ng,Chao‐Kai Chou,L P Ting,(unknown),S H Han,Chung-Ming Chang	31
20	Selective suppression of insulin-induced proliferation of cultured human hepatoma cells by somatostatin. 1987 ·Journal of Clinical Investigation ·Chao‐Kai Chou,L.‐T. Ho,L P Ting,Cheng Hu,(unknown),Wei-Chun Chang,C S Suen,Ming Huang,Chung-Ming Chang	46

About Chao‐Kai Chou

Chao‐Kai Chou is a scholar working on Biotechnology, Oncology and Immunology, having authored 77 papers that have together received 5.2k indexed citations. Recurring topics across this work include Microfluidic and Capillary Electrophoresis Applications (7 papers), Cancer-related Molecular Pathways (6 papers) and Advanced Biosensing Techniques and Applications (6 papers). The work is most often cited by research in Oncology (1.5k citations), Immunology (937 citations) and Molecular Biology (2.8k citations). Chao‐Kai Chou has collaborated with scholars based in Taiwan, United States and China. Frequent co-authors include Mien‐Chie Hung, O M Rosen, Roberto Gherzi, David Russell, Hsiao‐Sheng Liu, Ping‐Hung Chen, Ming‐Shiou Jan, Jung-Mao Hsu, Weiya Xia and Jennifer L. Hsu. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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