William E. Mitch

51.9k total citations · 17 hit papers
312 papers, 37.4k citations indexed

About

William E. Mitch is a scholar working on Molecular Biology, Cell Biology and Physiology. According to data from OpenAlex, William E. Mitch has authored 312 papers receiving a total of 37.4k indexed citations (citations by other indexed papers that have themselves been cited), including 107 papers in Molecular Biology, 102 papers in Cell Biology and 102 papers in Physiology. Recurrent topics in William E. Mitch's work include Muscle metabolism and nutrition (93 papers), Dialysis and Renal Disease Management (63 papers) and Metabolism and Genetic Disorders (58 papers). William E. Mitch is often cited by papers focused on Muscle metabolism and nutrition (93 papers), Dialysis and Renal Disease Management (63 papers) and Metabolism and Genetic Disorders (58 papers). William E. Mitch collaborates with scholars based in United States, China and Italy. William E. Mitch's co-authors include S. Russ Price, Alfred L. Goldberg, Giuseppe Remuzzi, Barry M. Brenner, Shahnaz Shahinfar, Dick de Zeeuw, William F. Keane, Mark E. Cooper, Hans‐Henrik Parving and Stewart H. Lecker and has published in prestigious journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

William E. Mitch

308 papers receiving 36.0k citations

Hit Papers

Effects of Losartan on Re... 1976 2026 1992 2009 2001 1999 2007 2004 2003 1000 2.0k 3.0k 4.0k 5.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy
    2001 5.4k citations Barry M. Brenner, Mark E. Cooper et al. profile →
  2. Diabetes and Cardiovascular Disease
    1999 2.1k citations Scott M. Grundy, Ivor J. Benjamin et al. Circulation profile →
  3. A proposed nomenclature and diagnostic criteria for protein–energy wasting in acute and chronic kidney disease
    2007 1.4k citations Joel D. Kopple, George A. Kaysen et al. Kidney International profile →
  4. Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
    2004 1.3k citations James L. Bailey, S. Russ Price et al. profile →
  5. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
    2003 1.2k citations Ulf Landmesser, Sergey Dikalov et al. Journal of Clinical Investigation profile →
  6. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
    2003 1.2k citations Ulf Landmesser, Sergey Dikalov et al. Journal of Clinical Investigation profile →
  7. AHA Dietary Guidelines
    2000 1.2k citations Robert H. Eckel, Barbara V. Howard et al. Circulation profile →
  8. Protein Degradation by the Ubiquitin–Proteasome Pathway in Normal and Disease States
    2006 959 citations William E. Mitch et al. Journal of the American Society of Nephrology profile →
  9. Mechanisms of Muscle Wasting — The Role of the Ubiquitin–Proteasome Pathway
    1996 917 citations William E. Mitch et al. profile →
  10. Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: Lessons from RENAAL
    2004 731 citations Dick de Zeeuw, Giuseppe Remuzzi et al. Kidney International profile →
  11. A method for estimating nitrogen intake of patients with chronic renal failure
    1985 633 citations William E. Mitch et al. Kidney International profile →
  12. Etiology of the Protein-Energy Wasting Syndrome in Chronic Kidney Disease: A Consensus Statement From the International Society of Renal Nutrition and Metabolism (ISRNM)
    2013 629 citations George A. Kaysen, William E. Mitch et al. profile →
  13. Muscle Protein Breakdown and the Critical Role of the Ubiquitin-Proteasome Pathway in Normal and Disease States
    1999 592 citations William E. Mitch et al. profile →
  14. Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions
    2004 575 citations Jie Du, Xiaonan Wang et al. Journal of Clinical Investigation profile →
  15. Albuminuria, a Therapeutic Target for Cardiovascular Protection in Type 2 Diabetic Patients With Nephropathy
    2004 567 citations Dick de Zeeuw, Giuseppe Remuzzi et al. Circulation profile →
  16. Mechanisms of muscle wasting in chronic kidney disease
    2014 447 citations William E. Mitch et al. profile →
  17. A SIMPLE METHOD OF ESTIMATING PROGRESSION OF CHRONIC RENAL FAILURE
    1976 356 citations William E. Mitch et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
William E. Mitch 11.4k 11.1k 11.0k 7.9k 6.0k 312 37.4k
Christoph Wanner 14.1k 1.2× 9.5k 0.9× 10.2k 0.9× 8.4k 1.1× 17.9k 3.0× 716 46.4k
Barry M. Brenner 15.1k 1.3× 7.8k 0.7× 5.2k 0.5× 13.0k 1.6× 8.6k 1.4× 296 39.7k
Ann Marie Schmidt 3.4k 0.3× 13.3k 1.2× 9.7k 0.9× 3.6k 0.5× 11.7k 1.9× 395 49.7k
Mark E. Cooper 13.2k 1.2× 11.6k 1.0× 5.4k 0.5× 12.7k 1.6× 17.9k 3.0× 514 48.8k
Nosratola D. Vaziri 8.1k 0.7× 9.8k 0.9× 6.4k 0.6× 3.8k 0.5× 4.0k 0.7× 465 31.4k
Peter Stenvinkel 19.6k 1.7× 5.3k 0.5× 9.2k 0.8× 3.7k 0.5× 3.6k 0.6× 648 38.2k
Jesús Egido 7.1k 0.6× 10.6k 1.0× 2.9k 0.3× 5.6k 0.7× 3.0k 0.5× 621 31.6k
James R. Sowers 3.3k 0.3× 10.0k 0.9× 8.7k 0.8× 15.6k 2.0× 14.8k 2.4× 689 42.7k
Alberto Ortíz 9.8k 0.9× 8.7k 0.8× 4.3k 0.4× 3.0k 0.4× 2.4k 0.4× 847 28.9k
Joseph V. Bonventre 21.1k 1.9× 21.0k 1.9× 4.6k 0.4× 3.3k 0.4× 1.8k 0.3× 516 55.9k

Countries citing papers authored by William E. Mitch

Since Specialization
Citations

This map shows the geographic impact of William E. Mitch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William E. Mitch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William E. Mitch more than expected).

Fields of papers citing papers by William E. Mitch

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William E. Mitch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William E. Mitch. The network helps show where William E. Mitch may publish in the future.

Co-authorship network of co-authors of William E. Mitch

This figure shows the co-authorship network connecting the top 25 collaborators of William E. Mitch. A scholar is included among the top collaborators of William E. Mitch based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William E. Mitch. William E. Mitch is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Lee, Tae Hoon, Eric K. Peden, Qingtian Li, et al.. (2025). Interplay between Skeletal Muscle Catabolism and Remodeling of Arteriovenous Fistula by Yes-Associated Protein 1 (YAP1) Signaling. Journal of the American Society of Nephrology. 36(5). 845–858. 1 indexed citations
2.
Song, Jia, José Alberto Navarro‐García, Jiao Wu, et al.. (2023). Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation. Journal of Clinical Investigation. 133(19). 38 indexed citations
3.
Zhang, Ping, et al.. (2020). Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40. American Journal of Physiology-Endocrinology and Metabolism. 318(5). E625–E635. 33 indexed citations
4.
Vangala, Chandan, Jingbo Niu, Colin R. Lenihan, et al.. (2018). Proton Pump Inhibitors, Histamine-2 Receptor Antagonists, and Hip Fracture Risk among Patients on Hemodialysis. Clinical Journal of the American Society of Nephrology. 13(10). 1534–1541. 14 indexed citations
5.
Wang, Yuguo, Jia Li, Zhaoyong Hu, et al.. (2017). AMP-activated protein kinase/myocardin-related transcription factor-A signaling regulates fibroblast activation and renal fibrosis. Kidney International. 93(1). 81–94. 36 indexed citations
6.
Thomas, Sandhya S., Yanjun Dong, Liping Zhang, & William E. Mitch. (2013). Signal regulatory protein-α interacts with the insulin receptor contributing to muscle wasting in chronic kidney disease. Kidney International. 84(2). 308–316. 54 indexed citations
7.
Workeneh, Biruh, Helbert Rondon‐Berrios, Ping Zhang, et al.. (2006). Development of a Diagnostic Method for Detecting Increased Muscle Protein Degradation in Patients with Catabolic Conditions. Journal of the American Society of Nephrology. 17(11). 3233–3239. 96 indexed citations
8.
Du, Jie, Xiaonan Wang, James L. Bailey, et al.. (2004). Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions. Journal of Clinical Investigation. 113(1). 115–123. 575 indexed citations breakdown →
9.
Du, Jie, Xiaonan Wang, James L. Bailey, et al.. (2004). Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions. Journal of Clinical Investigation. 113(1). 115–123. 45 indexed citations
10.
Zeeuw, Dick de, Giuseppe Remuzzi, Hans‐Henrik Parving, et al.. (2004). Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: Lessons from RENAAL. Kidney International. 65(6). 2309–2320. 731 indexed citations breakdown →
11.
Landmesser, Ulf, Sergey Dikalov, S. Russ Price, et al.. (2003). Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. Journal of Clinical Investigation. 111(8). 1201–1209. 1176 indexed citations breakdown →
12.
Landmesser, Ulf, Sergey Dikalov, S. Russ Price, et al.. (2003). Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. Journal of Clinical Investigation. 111(8). 1201–1209. 1224 indexed citations breakdown →
13.
Kaysen, George A., Joel A. Dubin, Hans‐Georg Müller, et al.. (2003). Impact of albumin synthesis rate and the acute phase response in the dual regulation of fibrinogen levels in hemodialysis patients11See Editorial by Goodship, p. 379.. Kidney International. 63(1). 315–322. 27 indexed citations
14.
Mitch, William E.. (2002). Malnutrition: a frequent misdiagnosis for hemodialysis patients. Journal of Clinical Investigation. 110(4). 437–439. 6 indexed citations
15.
Mitch, William E.. (2002). Malnutrition: a frequent misdiagnosis for hemodialysis patients. Journal of Clinical Investigation. 110(4). 437–439. 83 indexed citations
16.
Grundy, Scott M., Ivor J. Benjamin, Gregory L. Burke, et al.. (1999). Diabetes and Cardiovascular Disease. Circulation. 100(10). 1134–1146. 2118 indexed citations breakdown →
17.
Myers, Bryan D., Robert G. Nelson, George W. Williams, et al.. (1991). Glomerular function in Pima Indians with noninsulin-dependent diabetes mellitus of recent onset.. Journal of Clinical Investigation. 88(2). 524–530. 101 indexed citations
18.
Mitch, William E.. (1986). The Progressive nature of renal disease. Churchill Livingstone eBooks. 102 indexed citations
19.
Kelly, Ralph A. & William E. Mitch. (1983). Creatinine, Uric Acid, and Other Nitrogenous Waste Products: Clinical Implication of the Imbalance Between Their Production and Elimination in Uremia. Seminars in Nephrology. 3(4). 286–294. 5 indexed citations
20.
Mitch, William E. & Marion Walser. (1977). Nitrogen balance of uremic patients receiving branched-chain ketoacids and the hydroxy-analogue of methionine as substitutes for the respective amino acids.. PubMed. 8(2). 341–4. 31 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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