Valentine M. Macaulay

6.0k citations

73 papers · 4.5k indexed · 1 hit paper · h-index 35

Endocrinology, Diabetes and Metabolism top 0.5%
- Growth Hormone and Insulin-like Growth Factors 30
Cancer Research top 1%
- Cancer, Hypoxia, and Metabolism 14
Oncology top 2%
- Cancer-related Molecular Pathways 8
- Cancer Cells and Metastasis 4
Molecular Biology top 2%
- Metabolism, Diabetes, and Cancer 13
- PI3K/AKT/mTOR signaling in cancer 9
- DNA Repair Mechanisms 5
Pulmonary and Respiratory Medicine top 5%
- Prostate Cancer Treatment and Research 6

Co-authors: Johann Riedemann Andrew Protheroe J.S.P. Yuen Martin P. Playford Meenali Chitnis Simon Brewster Erin A. Bohula Giles Hellawell
Cited by: Endocrinology, Diabetes and Metabolism Cancer Research Oncology
Journals: Proceedings of the National Academy of Sciences (1 paper)Nucleic Acids Research (1 paper)Journal of Biological Chemistry (1 paper)
Partner nations: United Kingdom United States Austria

In The Last Decade

Valentine M. Macaulay

72 papers receiving 4.5k citations

Hit Papers

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Peers

Countries citing papers authored by Valentine M. Macaulay

Since Specialization

Citations

This map shows the geographic impact of Valentine M. Macaulay's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Valentine M. Macaulay with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Valentine M. Macaulay more than expected).

Fields of papers citing papers by Valentine M. Macaulay

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Valentine M. Macaulay. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Valentine M. Macaulay. The network helps show where Valentine M. Macaulay may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Valentine M. Macaulay, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Valentine M. Macaulay Line = papers co-authored together Valentine M. Macaulay links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A Phase Ib/II study of IGF-neutralising antibody xentuzumab with enzalutamide in metastatic castration-resistant prostate cancer British Journal of Cancer ·Valentine M. Macaulay,Simon Lord,Syed A. Hussain,Pablo Maroto,Robert H. Jones,Miguel Ángel Climent,Natalie Cook,Chia‐Chi Lin,Shian‐Shiang Wang,Diletta Bianchini,Mark Bailey,Laura Schlieker,Thomas Bogenrieder,Johann S. de Bono	2023	3
2	Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction Cancer Research ·Guillaume Rieunier,Xiaoning Wu,Letitia Harris,Jack V. Mills,Ashwin Nandakumar,Laura Colling,Elena Seraia,Stephanie B. Hatch,Daniel Ebner,Lisa K. Folkes,Ulrike Weyer-Czernilofsky,Thomas Bogenrieder,Anderson J. Ryan,Valentine M. Macaulay	2021	9
3	Bad to the Bone: The Role of the Insulin-Like Growth Factor Axis in Osseous Metastasis Clinical Cancer Research ·Guillaume Rieunier,Xiaoning Wu,Valentine M. Macaulay,Adrian V. Lee,Ulrike Weyer-Czernilofsky,Thomas Bogenrieder	2019	38
4	Radioresistant laryngeal cancers upregulate type 1 IGF receptor and exhibit increased cellular dependence on IGF and EGF signalling Clinical Otolaryngology ·Ali Qureishi,Guillaume Rieunier,Ketan Shah,Tamara Aleksic,Stuart C. Winter,Henrik Møller,Valentine M. Macaulay	2019	5
5	Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage Cancer Research ·Tamara Aleksic,Nicki Gray,Xiaoning Wu,Guillaume Rieunier,Eliot Osher,Jack V. Mills,Clare Verrill,Richard J. Bryant,Cheng Han,Kathryn Hutchinson,Adam Lambert,Rajeev Kumar,Freddie C. Hamdy,Ulrike Weyer-Czernilofsky,Michael P. Sanderson,Thomas Bogenrieder,Stephen Taylor,Valentine M. Macaulay	2018	50
6	TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy British Journal of Cancer ·Giacomo Pirovano,Thomas M. Ashton,Katharine Herbert,Richard J. Bryant,Clare Verrill,Lucia Cerundolo,Francesca M. Buffa,Remko Prevo,Iona Harrap,Anderson J. Ryan,Valentine M. Macaulay,W. Gillies McKenna,Geoff S. Higgins	2017	22
7	Insulin-Like Growth Factor (IGF) Pathway Targeting in Cancer: Role of the IGF Axis and Opportunities for Future Combination Studies Targeted Oncology ·Aaron D. Simpson,Wilfride Petnga,Valentine M. Macaulay,Ulrike Weyer-Czernilofsky,Thomas Bogenrieder	2017	125
8	Durable Response of Spinal Chordoma to Combined Inhibition of IGF-1R and EGFR Frontiers in Oncology ·Tamara Aleksic,Lisa Browning,Martha Woodward,Rachel R. Phillips,Suzanne Page,Shirley Henderson,Nicholas A. Athanasou,Olaf Ansorge,Duncan Whitwell,Sarah Pratap,A. Bassim Hassan,Mark R. Middleton,Valentine M. Macaulay	2016	31
9	Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation Cancer Cell ·Sophia X. Pfister,Enni Markkanen,Yanyan Jiang,Sovan Sarkar,Mick Woodcock,Giulia Orlando,Ioanna Mavrommati,Chen‐Chun Pai,Lykourgos‐Panagiotis Zalmas,Neele Drobnitzky,Grigory L. Dianov,Clare Verrill,Valentine M. Macaulay,Songmin Ying,Nicholas B. La Thangue,Vincenzo D’Angiolella,Anderson J. Ryan,Timothy C. Humphrey	2015	224
10	Accelerated methotrexate, vinblastine, doxorubicin, and cisplatin (AMVAC) as neoadjuvant chemotherapy for patients with muscle‐invasive transitional cell carcinoma of the bladder Cancer ·Christopher Blick,Peter Hall,Thinn Pwint,Faisal Al‐Terkait,Jeremy Crew,Thomas Powles,Valentine M. Macaulay,Nicholas P. Munro,David Douglas,Neviana Kilbey,Andrew Protheroe,John Chester	2012	35
11	Depletion of the type 1 IGF receptor delays repair of radiation-induced DNA double strand breaks Radiotherapy and Oncology ·Benjamin W. Turney,Martin Kerr,Meenali Chitnis,Kunal A. Lodhia,Yong Wang,Johann Riedemann,Mark Rochester,Andrew Protheroe,Simon Brewster,Valentine M. Macaulay	2012	37
12	Type 1 Insulin-like Growth Factor Receptor Translocates to the Nucleus of Human Tumor Cells Cancer Research ·Tamara Aleksic,Meenali Chitnis,Olga V. Perestenko,Shan Gao,Peter H. Thomas,Gareth D. H. Turner,Andrew Protheroe,Mark Howarth,Valentine M. Macaulay	2010	169
13	An adult Xp11.2 translocation renal carcinoma showing response to treatment with sunitinib Urologic Oncology Seminars and Original Investigations ·Thinn Pwint,Valentine M. Macaulay,S. A. Roberts,Mark Sullivan,Andrew Protheroe	2009	13
14	Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer Expert Opinion on Therapeutic Targets ·J.S.P. Yuen,Valentine M. Macaulay	2008	94
15	The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma Oncogene ·J.S.P. Yuen,Matthew E. Cockman,Mark Sullivan,Andrew Protheroe,Gareth D. H. Turner,Ian S. Roberts,Christopher W. Pugh,Haim Werner,Valentine M. Macaulay	2007	75
16	Silencing of the IGF1R gene enhances sensitivity to DNA-damaging agents in both PTEN wild-type and mutant human prostate cancer Cancer Gene Therapy ·Mark Rochester,Johann Riedemann,Giles Hellawell,Simon Brewster,Valentine M. Macaulay	2004	93
17	An in vivo model of intratumoural aromatase using aromatase‐transfected MCF7 human breast cancer cells International Journal of Cancer ·Kathryn Lee,Valentine M. Macaulay,Joanne Nicholls,Simone Detre,Alan Ashworth,M Dowsett	1995	21
18	Biological effects of stable overexpression of aromatase in human hormone-dependent breast cancer cells British Journal of Cancer ·Valentine M. Macaulay,Joanne Nicholls,Judith Gledhill,M.G. Rowlands,Mitch Dowsett,Alan Ashworth	1994	29
19	Insulin-like growth factors and cancerbreakdown → British Journal of Cancer ·Valentine M. Macaulay	1992	513
20	Somatostatin receptors are present in small‐cell but not in non‐small‐cell primary lung carcinomas: Relationship to EGF‐receptors International Journal of Cancer ·J.C. Reubi,Beatrice Waser,Mary N. Sheppard,Valentine M. Macaulay	1990	86

About Valentine M. Macaulay

Valentine M. Macaulay is a scholar working on Endocrinology, Diabetes and Metabolism, Cancer Research and Oncology, having authored 73 papers that have together received 4.5k indexed citations. Recurring topics across this work include Growth Hormone and Insulin-like Growth Factors (30 papers), Cancer, Hypoxia, and Metabolism (14 papers), Metabolism, Diabetes, and Cancer (13 papers), PI3K/AKT/mTOR signaling in cancer (9 papers), Cancer-related Molecular Pathways (8 papers), Prostate Cancer Treatment and Research (6 papers), DNA Repair Mechanisms (5 papers) and Cancer Cells and Metastasis (4 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (1.7k citations), Cancer Research (1.3k citations) and Oncology (1.3k citations). Valentine M. Macaulay has collaborated with scholars based in United Kingdom, United States and Austria. Frequent co-authors include Johann Riedemann, Andrew Protheroe, J.S.P. Yuen, Martin P. Playford, Meenali Chitnis, Simon Brewster, Erin A. Bohula, Giles Hellawell, Gareth D. H. Turner and Tamara Aleksic. Their work appears in journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Journal of Biological Chemistry.

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