Simone Detre

5.9k citations

63 papers · 4.2k indexed · 1 hit paper · h-index 30

Impact in

Cancer Research top 0.5%
- Breast Cancer Treatment Studies
- Cancer Genomics and Diagnostics
Oncology top 1%
- HER2/EGFR in Cancer Research
- Cancer Cells and Metastasis
- Cancer-related Molecular Pathways

Papers in ⓘ

Oncology 42
- HER2/EGFR in Cancer Research 27
- Cancer-related Molecular Pathways 7
- Cancer Cells and Metastasis 6
Genetics 32
- Estrogen and related hormone effects 30

Co-authors: Mitch Dowsett (48 shared papers)Janine Salter (23 shared papers)Ian E. Smith (17 shared papers)Margaret Hills (17 shared papers)Roger A’Hern (15 shared papers)Anthony Skene (8 shared papers)Geraldine Walsh (5 shared papers)Stephen Johnston (14 shared papers)
Journals: Clinical Cancer Research (8 papers)Breast Cancer Research (7 papers)Journal of Clinical Pathology (5 papers)Journal of Clinical Oncology (5 papers)Cancer Research (5 papers)
Partner nations: United Kingdom United States Switzerland

In The Last Decade

Simone Detre

61 papers receiving 4.1k citations

Hit Papers

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A "quickscore" method for immunohistochemical semiquantitation: validation for oestrogen receptor in breast carcinomas. 1995 · 693 citations

Peers

Countries citing papers authored by Simone Detre

Since Specialization

Citations

This map shows the geographic impact of Simone Detre's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simone Detre with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simone Detre more than expected).

Fields of papers citing papers by Simone Detre

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simone Detre. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simone Detre. The network helps show where Simone Detre may publish in the future.

Co-authors

The 25 scholars most cited alongside Simone Detre, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simone Detre Line = papers co-authored together Simone Detre links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 63 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A "quickscore" method for immunohistochemical semiquantitation: validation for oestrogen receptor in breast carcinomas. Journal of Clinical Pathology ·Simone Detre, G Saclani Jotti, Mitch Dowsett Hit paper breakdown →	1995	693
2	Prognostic Value of Ki67 Expression After Short-Term Presurgical Endocrine Therapy for Primary Breast Cancer JNCI Journal of the National Cancer Institute ·Mitch Dowsett, Ian E. Smith, S. Ebbs, J. Michael Dixon, Anthony Skene, Roger A’Hern, Janine Salter, Simone Detre, Margaret Hills, Geraldine Walsh	2007	469
3	Molecular Changes in Tamoxifen-Resistant Breast Cancer: Relationship Between Estrogen Receptor, HER-2, and p38 Mitogen-Activated Protein Kinase Journal of Clinical Oncology ·Maya Gutierrez, Simone Detre, Stephen Johnston, Syed K. Mohsin, Jiang Shou, D. Craig Allred, Rachel Schiff, C. Kent Osborne, Mitch Dowsett	2005	378
4	Short-Term Changes in Ki-67 during Neoadjuvant Treatment of Primary Breast Cancer with Anastrozole or Tamoxifen Alone or Combined Correlate with Recurrence-Free Survival Clinical Cancer Research ·Mitch Dowsett, Ian E. Smith, Steve R. Ebbs, J. Michael Dixon, Anthony Skene, C.D.M. Griffith, Irene Boeddinghaus, Janine Salter, Simone Detre, Margaret Hills, S. Ashley, Stephen Francis, Geraldine Walsh, (unknown)	2005	244
5	Biomarker Changes During Neoadjuvant Anastrozole, Tamoxifen, or the Combination: Influence of Hormonal Status and HER-2 in Breast Cancer—A Study from the IMPACT Trialists Journal of Clinical Oncology ·Mitch Dowsett, Steve R. Ebbs, J. Michael Dixon, Anthony Skene, C.D.M. Griffith, Irene Boeddinghaus, Janine Salter, Simone Detre, Margaret Hills, S. Ashley, Stephen Francis, Geraldine Walsh, Ian E. Smith	2005	229
6	A Phase II Placebo-Controlled Trial of Neoadjuvant Anastrozole Alone or With Gefitinib in Early Breast Cancer Journal of Clinical Oncology ·Ian E. Smith, Geraldine Walsh, Anthony Skene, Antonio Llombart‐Cussac, José Mayordomo, Simone Detre, Janine Salter, Emma Clark, Patrick Magill, Mitch Dowsett	2007	169
7	Reduced apoptosis and proliferation and increased Bcl-2 in residual breast cancer following preoperative chemotherapy Breast Cancer Research and Treatment ·Peter Ellis, Ian E. Smith, Simone Detre, Samantha Burton, Janine Salter, Roger A’Hern, G. Walsh, Stephen Johnston, Mitch Dowsett	1998	112
8	Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer. PubMed ·Stephen Johnston, Julia E. Head, Sunil Pancholi, Simone Detre, Lesley‐Ann Martin, Ian E. Smith, Mitch Dowsett	2003	111
9	Cytotoxicity Acquired by Conjugation of an Anti‐Thy_1.1 Monoclonal Antibody and the Ribosome‐Inactivating Protein, Gelonin European Journal of Biochemistry ·Philip E. Thorpe, Alexander N. F. BROWN, W. C. J. Ross, Alan J. Cumber, Simone Detre, D. C. Edwards, Anthony J.S. Davies, Fiorenzo Stirpe	1981	107
10	Extreme loss of immunoreactive p-Akt and p-Erk1/2 during routine fixation of primary breast cancer Breast Cancer Research ·Isabel Pinhel, Fiona MacNeill, Margaret J. Hills, Janine Salter, Simone Detre, Roger A’Hern, Ashutosh Nerurkar, Peter Osin, Ian E. Smith, Mitch Dowsett	2010	103
11	Influence of neoadjuvant anastrozole (Arimidex) on intratumoral estrogen levels and proliferation markers in patients with locally advanced breast cancer. PubMed ·Jürgen Geisler, Simone Detre, Hildegunn Berntsen, Lars Ottestad, Bernt Lindtjørn, M Dowsett, P Einstein Lønning	2001	100
12	Modification of the carbohydrate in ricin with metaperiodate — cyanoborohydride mixtures European Journal of Biochemistry ·Philip E. Thorpe, Simone Detre, Brian M. J. Foxwell, Alex N. F. Brown, David N. Skilleter, Glynn Wilson, J.A. Forrester, Fiorenzo Stirpe	1985	100
13	Induction of apoptosis by tamoxifen and ICI 182780 in primary breast cancer International Journal of Cancer ·Peter Ellis, Gloria Saccani‐Jotti, Robert B. Clarke, Stephen Johnston, Elizabeth Anderson, Anthony Howell, Roger A’Hern, Janine Salter, Simone Detre, Robert I. Nicholson, J.F.R. Robertson, Ian E. Smith, Mitch Dowsett	1997	98
14	Exon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer. PubMed ·A A Daffada, S R Johnston, I. E. Smith, Simone Detre, Nicholas King, M Dowsett	1995	92
15	Proliferation and Apoptosis as Markers of Benefit in Neoadjuvant Endocrine Therapy of Breast Cancer Clinical Cancer Research ·Mitch Dowsett, Ian E. Smith, Steve R. Ebbs, J. Michael Dixon, Anthony Skene, C.D.M. Griffith, Irene Boeddinghaus, Janine Salter, Simone Detre, Margaret Hills, S. Ashley, Stephen Francis, Geraldine Walsh, Roger A’Hern	2006	91
16	Preclinical antitumor activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer. PubMed ·Lloyd R. Kèlland, Victoria Smith, Melanie Valenti, Lisa Patterson, Paul A. Clarke, Simone Detre, D End, Angela Howes, M Dowsett, Paul Workman, SR Johnston	2001	79
17	Residual proliferative cancer burden to predict long-term outcome following neoadjuvant chemotherapy Annals of Oncology ·Amna Sheri, Ian E. Smith, Stephen Johnston, Roger A’Hern, Ashutosh Nerurkar, Robin L. Jones, Margaret Hills, Simone Detre, Sarah E. Pinder, W. Fraser Symmans, Mitch Dowsett	2014	78
18	Lapatinib Restores Hormone Sensitivity with Differential Effects on Estrogen Receptor Signaling in Cell Models of Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer with Acquired Endocrine Resistance Clinical Cancer Research ·Alexandra Léary, Suzanne Drury, Simone Detre, Sunil Pancholi, Anne E. Lykkesfeldt, Lesley‐Ann Martin, Mitch Dowsett, Stephen Johnston	2010	70
19	Evaluation of Ki-67 proliferation and apoptotic index before, during and after neoadjuvant chemotherapy for primary breast cancer Breast Cancer Research ·Russell Burcombe, George D. Wilson, Mitch Dowsett, Iftekhar Khan, Paul Richman, Frances Daley, Simone Detre, Andreas Makris	2006	68
20	Changes in breast cancer biomarkers in the IGF1R/PI3K pathway in recurrent breast cancer after tamoxifen treatment Endocrine Related Cancer ·Suzanne Drury, Simone Detre, Alexandra Léary, Janine Salter, Jorge S. Reis‐Filho, Violetta Barbashina, Caterina Marchiò, Elena López‐Knowles, Zara Ghazoui, Kai Habben, Susanne Arbogast, Stephen Johnston, M Dowsett	2011	67

About Simone Detre

Simone Detre is a scholar working on Oncology, Genetics, Cancer Research, Molecular Biology and Immunology, having authored 63 papers that have together received 4.2k indexed citations. Recurring topics across this work include Estrogen and related hormone effects (30 papers), HER2/EGFR in Cancer Research (27 papers), Breast Cancer Treatment Studies (22 papers), Cancer-related Molecular Pathways (7 papers), Cancer Cells and Metastasis (6 papers), Advanced Breast Cancer Therapies (5 papers), Immunotherapy and Immune Responses (4 papers) and Toxin Mechanisms and Immunotoxins (4 papers). The work is most often cited by research in Cancer Research (1.7k citations), Oncology (2.2k citations), Genetics (1.3k citations), Biotechnology (209 citations) and Pathology and Forensic Medicine (428 citations). Simone Detre has collaborated with scholars based in United Kingdom, United States and Switzerland. Frequent co-authors include Mitch Dowsett, Janine Salter, Ian E. Smith, Margaret Hills, Roger A’Hern, Anthony Skene, Geraldine Walsh, Stephen Johnston, J. Michael Dixon and M Dowsett. Their work appears in journals such as Clinical Cancer Research, Breast Cancer Research, Journal of Clinical Pathology, Journal of Clinical Oncology and Cancer Research.

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