Timothy P. Burkholder

945 citations

23 papers · 506 indexed · h-index 13

Co-authors: P. L. Fuchs Gary A. Flynn Elizabeth M. Kudlacz Edward W. Huber Michèle C. Smith Sandaruwan Geeganage Philippe Bey Kenneth D. Roth
Topics: Chemical Synthesis and Analysis (8 papers)Neuropeptides and Animal Physiology (6 papers)Pharmacological Receptor Mechanisms and Effects (3 papers)
Cited by: Geriatrics and Gerontology Physiology Organic Chemistry
Journals: Journal of the American Chemical Society Journal of Biological Chemistry Blood
Partner nations: United States Austria Canada

In The Last Decade

Timothy P. Burkholder

23 papers receiving 471 citations

Peers

Countries citing papers authored by Timothy P. Burkholder

Since Specialization

Citations

This map shows the geographic impact of Timothy P. Burkholder's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy P. Burkholder with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy P. Burkholder more than expected).

Fields of papers citing papers by Timothy P. Burkholder

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy P. Burkholder. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy P. Burkholder. The network helps show where Timothy P. Burkholder may publish in the future.

Co-authorship network of co-authors of Timothy P. Burkholder

This figure shows the co-authorship network connecting the top 25 collaborators of Timothy P. Burkholder. A scholar is included among the top collaborators of Timothy P. Burkholder based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Timothy P. Burkholder. Timothy P. Burkholder is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Discovery of chiral dihydropyridopyrimidinones as potent, selective and orally bioavailable inhibitors of AKT 2018 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Kenneth J. Henry,(unknown),(unknown),(unknown),(unknown),Óscar de Frutos,Pablo D. García,Carlos Mateos,(unknown),Yong Wang,(unknown),Bradley Condon,(unknown),(unknown),William J. Ehlhardt,(unknown),Mei Lai,Sandaruwan Geeganage,Timothy P. Burkholder	9
2	Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists 2015 ·Bioorganic & Medicinal Chemistry Letters ·Timothy P. Burkholder,(unknown),(unknown),Peter A. Lander,Matthew L. Brown,(unknown),Gregory L. Durst,Chahrzad Montrose‐Rafizadeh,Constance King,Harold E. Osborne,(unknown),Richard W. Zink,Lawrence E. Stramm,Thomas P. Burris,Guemalli R. Cardona,Debra L. Konkol,Charles A. Reidy,Michael E. Christe,Michaël Génin	8
3	Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells 2012 ·Journal of Biological Chemistry ·Bo Tan,Debra A. Young,(unknown),Tao Wang,Timothy I. Meier,Robert L. Shepard,Kenneth D. Roth,Yan Zhai,Karen Huss,Ming‐Shang Kuo,James R. Gillig,Saravanan Parthasarathy,Timothy P. Burkholder,Michèle C. Smith,Sandaruwan Geeganage,Genshi Zhao	135
4	Discovery of LY2457546: a multi-targeted anti-angiogenic kinase inhibitor with a novel spectrum of activity and exquisite potency in the acute myelogenous leukemia-Flt-3-internal tandem duplication mutant human tumor xenograft model 2011 ·Investigational New Drugs ·Timothy P. Burkholder,(unknown),(unknown),James R. Henry,(unknown),David Mendel,(unknown),(unknown),David A. Barda,Eileen L. Considine,Mark Uhlik,Yuefeng Chen,Liandong Ma,Laura J. Bloem,Jacqueline K. Akunda,Denis McCann,Manuel Sánchez-Félix,David K. Clawson,Michael Lahn,James J. Starling	16
5	Development and a Practical Synthesis of the JAK2 Inhibitor LY2784544 2011 ·Organic Process Research & Development ·David Mitchell,Kevin P. Cole,(unknown),(unknown),Timothy P. Burkholder,(unknown)	36
6	Abstract 2820: LY2784544, a small molecule JAK2 inhibitor, induces apoptosis in inflammatory breast cancer spheres through targeting IL-6-JAK-STAT3 pathway 2011 ·Cancer Research ·Liandong Ma,Baohui Zhao,Richard A. Walgren,(unknown),Timothy P. Burkholder	2
7	Developing and applying a gene functional association network for anti-angiogenic kinase inhibitor activity assessment in an angiogenesis co-culture model 2008 ·BMC Genomics ·Yuefeng Chen,Tao Wei,Lei Yan,Frank Lawrence,Hui-Rong Qian,Timothy P. Burkholder,James J. Starling,Jonathan M. Yingling,Jianyong Shou	17
8	The peripheral NK‐1/NK‐2 receptor antagonist MDL 105,172A inhibits tachykinin‐mediated respiratory effects in guinea‐pigs 1997 ·Journal of Autonomic Pharmacology ·Elizabeth M. Kudlacz,(unknown),Scott A. Shatzer,John H. Kehne,Timothy C. McCloskey,Timothy P. Burkholder	5
9	Synthesis and sar of 4-(1H-benzimidazole-2-carbonyl)piperidines with dual histamine H1/tachykinin NK1 receptor antagonist activity 1997 ·Bioorganic & Medicinal Chemistry Letters ·George D. Maynard,(unknown),John M. Kane,Timothy P. Burkholder,(unknown),(unknown),Elizabeth M. Kudlacz,Scott A. Shatzer,(unknown),Amy M. Farrell,(unknown)	12
10	Identification and chemical synthesis of MDL 105,212, a non-peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors 1996 ·Bioorganic & Medicinal Chemistry Letters ·Timothy P. Burkholder,Elizabeth M. Kudlacz,(unknown),(unknown),Scott A. Shatzer,George D. Maynard,(unknown),Stephen W. Horgan	24
11	In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist. 1996 ·Journal of Pharmacology and Experimental Therapeutics ·Elizabeth M. Kudlacz,Scott A. Shatzer,(unknown),(unknown),Marc Poirot,P L van Giersbergen,Timothy P. Burkholder	24
12	ChemInform Abstract: Identification and Chemical Synthesis of MDL 105,212, a Non‐Peptide Tachykinin Antagonist with High Affinity for NK1 and NK2 Receptors. 1996 ·ChemInform ·Timothy P. Burkholder,Elizabeth M. Kudlacz,(unknown),(unknown),Scott A. Shatzer,George D. Maynard,(unknown),Stephen W. Horgan	1
13	Effect of MDL 105,212, a nonpeptide NK-1/NK-2 receptor antagonist in an allergic guinea pig model. 1996 ·Journal of Pharmacology and Experimental Therapeutics ·Elizabeth M. Kudlacz,(unknown),(unknown),Timothy P. Burkholder	26
14	ChemInform Abstract: The Synthesis of 6‐Amino‐5‐oxo‐7‐phenyl‐1,4‐oxazepines as Conformationally Constrained Gauche (‐)‐Dipeptide Mimetics. 1993 ·ChemInform ·Timothy P. Burkholder,Edward W. Huber,Gary A. Flynn	1
15	Synthesis of 6-amino-5-oxo-7-phenyl-1,4-oxazepines as conformationally constrained gauche (−) dipeptide mimetics 1993 ·Bioorganic & Medicinal Chemistry Letters ·Timothy P. Burkholder,Edward W. Huber,Gary A. Flynn	18
16	Acid-catalyzed O-allylation of β-hydroxy-α-amino acids: an entry into conformationally constrained dipeptide surrogates 1992 ·Bioorganic & Medicinal Chemistry Letters ·Timothy P. Burkholder,(unknown),Eugène L. Giroux,Gary A. Flynn	4
17	ChemInform Abstract: An Acyliminium Ion Route to cis‐ and trans‐“anti”‐Phe‐Gly Dipeptide Mimetics. 1992 ·ChemInform ·Gary A. Flynn,Timothy P. Burkholder,Edward W. Huber,Philippe Bey	1
18	An acyliminium ion route to and “Anti” phe-gly dipeptide mimetics 1991 ·Bioorganic & Medicinal Chemistry Letters ·Gary A. Flynn,Timothy P. Burkholder,Edward W. Huber,Philippe Bey	33
19	Synthesis via vinyl sulfones. 38. Total synthesis of the cephalotaxus alkaloids dl-cephalotaxine, dl-11-hydroxycephalotaxine, and dl-drupacine 1990 ·Journal of the American Chemical Society ·Timothy P. Burkholder,(unknown)	59
20	Synthesis via vinyl sulfones. 27. Total synthesis of cephalotaxine. The first example of an intramolecular [4 + 2] cycloaddition where the dienophile has been delivered from the face opposite to the tethering moiety 1988 ·Journal of the American Chemical Society ·Timothy P. Burkholder,P. L. Fuchs	46

About Timothy P. Burkholder

Timothy P. Burkholder is a scholar working on Cellular and Molecular Neuroscience, Genetics and Molecular Biology, having authored 23 papers that have together received 506 indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (8 papers), Neuropeptides and Animal Physiology (6 papers) and Pharmacological Receptor Mechanisms and Effects (3 papers). The work is most often cited by research in Geriatrics and Gerontology (61 citations), Physiology (29 citations) and Organic Chemistry (161 citations). Timothy P. Burkholder has collaborated with scholars based in United States, Austria and Canada. Frequent co-authors include P. L. Fuchs, Gary A. Flynn, Elizabeth M. Kudlacz, Edward W. Huber, Michèle C. Smith, Sandaruwan Geeganage, Philippe Bey, Kenneth D. Roth, Karen Huss and James R. Gillig. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Blood.

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