Philippe Bey

5.5k citations

86 papers · 4.6k indexed · 1 hit paper · h-index 34

Impact in

Biochemistry top 0.1%
- Amino Acid Enzymes and Metabolism
Pharmaceutical Science top 0.5%
- Fluorine in Organic Chemistry

Papers in ⓘ

Molecular Biology 63
- Polyamine Metabolism and Applications 22
- Chemical Synthesis and Analysis 18
- Biochemical and Molecular Research 6
- Enzyme function and inhibition 6
Biochemistry 26
- Amino Acid Enzymes and Metabolism 26

Co-authors: Charles Danzin (11 shared papers)Patrick Casara (5 shared papers)Michael J. Jung (7 shared papers)Jean‐Paul Vevert (1 shared paper)Brian W. Metcalf (1 shared paper)Pierre S. Mamont (4 shared papers)Norton P. Peet (16 shared papers)Jeffrey Grove (2 shared papers)
Journals: Journal of Medicinal Chemistry (13 papers)Tetrahedron Letters (13 papers)Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Neurochemistry (5 papers)The Journal of Organic Chemistry (5 papers)
Partner nations: United States France United Kingdom

In The Last Decade

Philippe Bey

84 papers receiving 4.1k citations

Hit Papers

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Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C.4.1.1.17) by substrate and product analogs 1978 · 880 citations

Peers

Countries citing papers authored by Philippe Bey

Since Specialization

Citations

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Fields of papers citing papers by Philippe Bey

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philippe Bey. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philippe Bey. The network helps show where Philippe Bey may publish in the future.

Co-authors

The 25 scholars most cited alongside Philippe Bey, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Philippe Bey Line = papers co-authored together Philippe Bey links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 86 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C.4.1.1.17) by substrate and product analogs Journal of the American Chemical Society ·Brian W. Metcalf, Philippe Bey, Charles Danzin, Michael J. Jung, Patrick Casara, Jean‐Paul Vevert Hit paper breakdown →	1978	880
2	Anti-proliferative properties of DL-α-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase Biochemical and Biophysical Research Communications ·Pierre S. Mamont, Marie-Christine Duchesne, Jeffrey Grove, Philippe Bey	1978	367
3	Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis Nature Medicine ·Hikaru Sugimoto, Valerie S. LeBleu, Dattatreyamurty Bosukonda, Peter Keck, Gangadhar Taduri, Wibke Bechtel‐Walz, Hirokazu Okada, William D. Carlson, Philippe Bey, Mary Rusckowski, Björn Tampe, Désirée Tampe, Keizo Kanasaki, Michael Zeisberg, Raghu Kalluri	2012	183
4	Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites. Journal of Biological Chemistry ·R. Poulin, Li‐Fan Lu, Bradley L. Ackermann, Philippe Bey, Anthony E. Pegg	1992	179
5	Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture. Proceedings of the National Academy of Sciences ·Pierre S. Mamont, Peter Böhlen, Peter P. McCann, Philippe Bey, Francis Schuber, Chantal Tardif	1976	177
6	Stereospecific method to (E) and (Z) terminal fluoroolefins and its application to the synthesis of 2'-deoxy-2'-fluoromethylenenucleosides as potential inhibitors of ribonucleoside diphosphate reductase Journal of the American Chemical Society ·James R. McCarthy, Donald P. Matthews, David M. Stemerick, Edward W. Huber, Philippe Bey, Bruce Lippert, Ronald D. Snyder, Prasad S. Sunkara	1991	169
7	.alpha.-Diketone and .alpha.-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinases Journal of Medicinal Chemistry ·Michael R. Angelastro, Shujaath Mehdi, Joseph P. Burkhart, Norton P. Peet, Philippe Bey	1990	131
8	N-(2,3-Butadienyl)-1,4-butanediamine derivatives: potent irreversible inactivators of mammalian polyamine oxidase Journal of Medicinal Chemistry ·Philippe Bey, Frank N. Bolkenius, Nikolaus Seiler, Patrick Casara	1985	120
9	Enzyme-activated irreversible inhibitors of monoamine oxidase: phenylallylamine structure-activity relationships Journal of Medicinal Chemistry ·Ian A. McDonald, Jean Michel Lacoste, Philippe Bey, Michael G. Palfreyman, Monique Zreika	1985	110
10	Effect of α-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on polyamine levels in rat tissues Life Sciences ·Charles Danzin, Michel J. Jung, Jeffrey Grove, Philippe Bey	1979	106
11	Synthesis of peptidyl fluoromethyl ketones and peptidyl .alpha.-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G Journal of Medicinal Chemistry ·Norton P. Peet, Joseph P. Burkhart, Michael R. Angelastro, Eugène L. Giroux, Shujaath Mehdi, Philippe Bey, Michael Kolb, Bernhard Neises, Daniel Schirlin	1990	103
12	DL-.alpha.-(Difluoromethyl)arginine: a potent enzyme-activated irreversible inhibitor of bacterial arginine decarboxylases Biochemistry ·Arja Kallio, Peter P. McCann, Philippe Bey	1981	101
13	Direct synthesis of .alpha.-halogenomethyl-.alpha.-amino acids from the parent .alpha.-amino acids The Journal of Organic Chemistry ·Philippe Bey, Jean Paul Vevert, V. Van Dorsselaer, Michael Kolb	1979	96
14	Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain Biochemical and Biophysical Research Communications ·Shujaath Mehdi, Michael R. Angelastro, Jeffery S. Wiseman, Philippe Bey	1988	95
15	4',5'-Unsaturated-5'-fluoro adenosine nucleosides: potent mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase Journal of the American Chemical Society ·James R. McCarthy, Esa T. Jarvi, Donald P. Matthews, M. L. EDWARDS, Nellikunja J. Prakash, Terry L. Bowlin, Shujaath Mehdi, Prasad S. Sunkara, Philippe Bey	1989	85
16	.alpha.-(Fluoromethyl)dehydroornithine and .alpha.-(fluoromethyl)dehydroputrescine analogs as irreversible inhibitors of ornithine decarboxylase Journal of Medicinal Chemistry ·Philippe Bey, F. Gerhart, V. Van Dorsselaer, Charles Danzin	1983	83
17	Specific inhibition of polyamine oxidase in vivo is a method for the elucidation of its physiological role Biochimica et Biophysica Acta (BBA) - General Subjects ·Frank N. Bolkenius, Philippe Bey, Nikolaus Seiler	1985	78
18	Analogs of ornithine as inhibitors of ornithine decarboxylase. New deductions concerning the topography of the enzyme's active site Journal of Medicinal Chemistry ·Philippe Bey, Charles Danzin, V. Van Dorsselaer, Pierre S. Mamont, Michael J. Jung, Chantal Tardif	1978	75
19	Synthesis of 21,21-Difluoro-3β-hydroxy-20-methylpregna-5,20-diene and 5,16,20-Triene as potential inhibitors of steroid C17(20) lyase Bioorganic & Medicinal Chemistry ·Philip M. Weintraub, Amy K. Holland, Cynthia A. Gates, William R. Moore, Robert J. Resvick, Philippe Bey, Norton P. Peet	2003	72
20	An efficient synthesis of novel .alpha.-diketone and .alpha.-keto ester derivatives of N-protected amino acids and peptides The Journal of Organic Chemistry ·Michael R. Angelastro, Norton P. Peet, Philippe Bey	1989	56

About Philippe Bey

Philippe Bey is a scholar working on Molecular Biology, Biochemistry, Organic Chemistry, Pharmaceutical Science and Cell Biology, having authored 86 papers that have together received 4.6k indexed citations. Recurring topics across this work include Amino Acid Enzymes and Metabolism (26 papers), Polyamine Metabolism and Applications (22 papers), Chemical Synthesis and Analysis (18 papers), Fluorine in Organic Chemistry (10 papers), Metabolism and Genetic Disorders (7 papers), Biochemical and Molecular Research (6 papers), Peptidase Inhibition and Analysis (6 papers) and Enzyme function and inhibition (6 papers). The work is most often cited by research in Biochemistry (1.4k citations), Pharmaceutical Science (697 citations), Molecular Biology (3.1k citations), Organic Chemistry (1.2k citations) and Pharmacology (564 citations). Philippe Bey has collaborated with scholars based in United States, France and United Kingdom. Frequent co-authors include Charles Danzin, Patrick Casara, Michael J. Jung, Jean‐Paul Vevert, Brian W. Metcalf, Pierre S. Mamont, Norton P. Peet, Jeffrey Grove, Michael R. Angelastro and Shujaath Mehdi. Their work appears in journals such as Journal of Medicinal Chemistry, Tetrahedron Letters, Bioorganic & Medicinal Chemistry Letters, Journal of Neurochemistry and The Journal of Organic Chemistry.

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